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| 1 | Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues显示文摘Reactive oxygen species (ROS) are produced under oxidative stress, such as high oxygen concentration and during the metabolic consumption of oxygen molecules. Male reproductive tissues appear to be continuously exposed to ROS produced by active metabolism. In addition, spermatozoa must pass through a high oxygen environ-ment during the mating process. Thus, to maintain viable reproductive ability, a protective mechanism against oxida-tive stress is of importance. Here, we overview our current understanding of the cooperative function of antioxidative and redox systems that are involved in male fertility. Superoxide dismutase and glutathione peroxidase are major enzymes that scavenge harmful ROS in male reproductive organs. In turn, glutathione and thioredoxin systems constitute the main redox systems that repair oxidized and damaged molecules and also play a role in regulating a variety of cellular functions. While glutathione functions as an antioxidant by donating electrons to glutathione peroxidase and thioredoxin donates electrons to peroxiredoxin as a counterpart of glutathione peroxidase. In addition,aldo-keto reductases, which detoxify carbonyl compounds produced by oxidative stress, are present at high levels in the epithelia of the genital tract and Sertoli cells of the testis. Since these systems are involved in cross-talk, a comprehensive understanding will be required to maintain the physiological functions of male reproductive system.( Asian J Andro12003 Sep; 5: 231-242) | Junichi Fujii Yoshihito Iuchi Shingo Matsuki Tatsuya Ishii | 2003 | Asian Journal of Andrology2003，5，3： | 19 |
| 2 | 霉菌毒素及其毒性效应的研究进展显示文摘霉菌毒素是霉菌在谷物的田间生长阶段、收获和储藏或加工过程中产生的次生代谢产物,对动物生产性能和人类健康有极大的危害。文章综述了霉菌毒素的结构特点、产生条件、毒素间的互作效应及毒素对动物的毒性效应等方面的最新研究进展,旨在增加对霉菌毒素及其危害的了解。 | 龙定彪 罗敏 肖融 刘作华 | 2015 | 黑龙江畜牧兽医2015，，6： | 7 |
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