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| 1 | Trisomy 3 may predict a poor response of gastric MALT lymphoma to Helicobacter pylori eradication therapy显示文摘AIM: To investigate the relation of the response to Helicobacter pylori eradication therapy to the depth of tumor invasion and chromosome abnormalities in patients with mucosaassociated lymphoid tissue (MALT) lymphoma and to determine the clinical value of aneuploidy.METHODS: We studied 13 patients with localized gastric MALT lymphoma of stage E1. Before eradication therapy,the depth of tumor invasion was assessed by endoscopic ultrasonography in 8 patients and by endoscopic examination and gastrointestinal series in the remaining patients. To detect chromosomal abnormalities, paraffin-embedded tissue sections of diagnostic biopsy specimens underwent tissuefluorescence in situ hybridization (FISH), using chromosomespecific α-satellite DNA probes for chromosomes 3,7,12,and 18 and YAC clones for t(11;18)(q21;q21).RESULTS: Seven of the 13 patients had complete regression(CR) in response to H pylori eradication therapy. No patient with CR had submucosal tumor invasion. Trisomy 18 was seen in 1 patient with CR, and both trisomies 12 and 18 were present in another patient with CR. All patients with no response or progressive disease had deep submucosal tumor invasion and showed t(11;18)(q21;q21) or trisomy 3. Trisomy 7 was not detected in this series of patients.CONCLUSION: The depth of tumor invasion is an accurate predictor of the response of stage E1 MALT lymphoma to H pylori eradication therapy and is closely associated with the presence of chromosomal abnormalities. Trisomy 3 may predict the aggressive development of MALT lymphoma. | Sawako Taji Kenichi Nomura Yosuke Matsumoto Hideaki Sakabe Naohisa Yoshida Shoji Mitsufuji Kazuhiro Nishida Shigeo Horiike Shigeo Nakamura Masuji Morita Masafumi Taniwaki | 2005 | World Journal of Gastroenterology2005，11，1： | 6 |
| 2 | Diagnosis of follicular lymphoma of the gastrointestinaltract:A better initial diagnostic workup显示文摘Due to an increasing incidence and more frequent recognition by endoscopists, gastrointestinal follicular lymphoma has been established as a variant of follicular lymphoma. However, due to its rarity, there are no established guidelines on the optimal diagnostic strategy for patients with primary gastrointestinal follicular lymphoma or secondary gastrointestinal involvement of systemic follicular lymphoma. This review offers an overview and pitfalls to avoid during the initial diagnostic workup of this disease entity. Previously reported case reports, case series, and retrospective studies are reviewed and focus on the disease's endoscopic and histological features, the roles of computed tomography and positron emission tomography scanning, the clinical utility of the soluble interleukin-2 receptor, and the possible pathogenesis. | Masaya Iwamuro Eisei Kondo Katsuyoshi Takata Tadashi Yoshino Hiroyuki Okada | 2016 | World Journal of Gastroenterology2016，22，4： | 3 |
| 3 | 钢琴练习中引发的思考与探索——圣彼得堡音乐学院访问学习之有感显示文摘关于钢琴的演奏技巧和练习方法是很多钢琴演奏者探索和研究的主要话题之一,也是我们所需要准确掌握的主要方面。在许多关于钢琴演奏的文章和书籍中,钢琴练习方法更多是从手型(手指、手腕、手臂)、音型(单音、音程、三连音、跳音等)、踏板、音色等方面的被阐述,如约瑟夫·霍夫曼所著的《论钢琴演奏》、赵晓生所著的《钢琴演奏之道》、周广仁所编著的《钢琴演奏基础训练》以及卡尔·莱默尔与瓦尔特·吉泽金所著的《现代钢琴演奏技巧》等。而本文从新的角度出发,对于钢琴作品的演奏层次、音乐元素的异同和音的分组、分段练习过程中所引发的一些思考,来与大家探讨和分享。 | 印慧媛 | 2014 | 乐府新声(沈阳音乐学院学报)2014，32，1： | 0 |
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