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| 1 | 茶叶的抗过敏功效与机理显示文摘从过敏反应的概念、过敏症的群体分布、不同茶类及不同茶叶功能成分的抗过敏功效和抗过敏茶制品开发等方面进行了论述。重点介绍了茶多酚、儿茶素、甲基化儿茶素、茶皂素、茶黄素等茶叶功能成分对过敏反应尤其是速发型过敏具有显著预防与治疗效果,其中茶叶中儿茶素的甲基化产物展现了更为显著的抗过敏功效。一些发酵茶抗过敏能力优于绿茶,这可能与茶叶加工过程中生成除儿茶素外的其他抗过敏活性成分有关,如茶黄素等。茶叶功能成分主要通过以下途径起到抗过敏作用:抑制化学物质诱导的过敏反应;抑制组胺及过敏介质的释放;抑制活性因子如抗体、肾上腺素、酶等引起的过敏反应;促进肾上腺、垂体的活动而有消炎作用。 | 林勇 黄建安 王坤波 陈美艳 刘仲华 | 2019 | 中国茶叶2019，41，3： | 4 |
| 2 | Carpobrotus edulis(L.) N.E.Br. extract as a skin preserving agent: From traditional medicine to scientific validation显示文摘Objective:Carpobrotus edulis(L.)N.E.Br.is a succulent perennial plant native to South Africa and grows invasively in the Mediterranean basin.It is commonly used for the treatment of various diseases,including skin wound healing and regeneration,for which experimental validation is lacking.We therefore evaluated the skin healing properties by testing a C.edulis aqueous leaf extract(CAE)on cell cultures and in enzymatic assays.Methods:Micro-morphological analysis of leaves was carried out using scanning electron microscopy and light microscopy.Phytochemical features and antioxidant activity of CAE were evaluated by reversed-phase liquid chromatography coupled with diode array detection and electrospray ion trap mass spectrometry(RP-LC-DAD-ESI-MS),and in vitro cell-free assays.Biological activities were evaluated using keratinocytes and fibroblasts,as well as elastase,collagenase,and hyaluronidase.Results:CAE showed high carbohydrates(28.59%±0.68%),total phenols([101.9±6.0]g gallic acid equivalents/kg dry extract[DE]),and flavonoids([545.9±26.0]g rutin equivalents/kg DE).RP-LC-DAD-ESI-MS revealed the predominant presence of hydroxycinnamic acids(51.96%),followed by tannins(14.82%)and flavonols(11.32%).The extract was not cytotoxic,had a strong and dose-dependent antioxidant activity,and inhibited collagenase(>90%at 500 mg/m L)and hyaluronidase(100%at 1000 mg/m L).In cell culture experiments,CAE increased wound closure and collagen production,which was consistent with its high polyphenol content.Conclusion:Our data support the use of the C.edulis for skin care and the treatment of skin problems.Moreover,use of C.edulis for skin care purposes could be an eco-friendly solution to reduce its invasiveness in the environment. | Miriam Bazzicalupo Laura Cornara Bruno Burlando Alberta Cascini Marcella Denaro Antonella Smeriglio | 2021 | Journal of Integrative Medicine2021，19，6： | 0 |
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