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1Interventional radiology in living donor liver transplant显示文摘The shortage of deceased donor liver grafts led to the use of living donor liver transplant(LDLT).Patients who un-dergo LDLT have a higher risk of complications than those who undergo deceased donor liver transplantation(LT).Interventional radiology has acquired a key role in every LT program by treating the majority of vascular and nonvascular post-transplant complications,improving graft and patient survival and avoiding,in the majority of cases,surgical revision and/or re-transplant.The aim of this paper is to review indications,diagnostic modalities,technical considerations,achievements and potential complications of interventional radiology procedures after LDLT.Yu-Fan Cheng Hsin-You Ou Chun-Yen Yu Leo Leung-Chit Tsang Tung-Liang Huang Tai-Yi Chen Hsien-Wen Hsu Allan M Concerjero Chih-Chi Wang Shih-Ho Wang Tsan-Shiun Lin Yueh-Wei Liu Chee-Chien Yong Yu-Hung Lin Chih-Che Lin King-Wah Chiu Bruno Jawan Hock-Liew Eng Chao-Long Chen 2014World Journal of Gastroenterology2014,20,20:5
2Risk factors for de novo hepatitis B infection in pediatric living donor liver transplantation显示文摘AIM: To investigate the incidence of de novo hepatitis B virus(HBV) infection after pediatric living donor liver transplantation(LDLT) and to analyze the risk factors associated with this de novo HBV infection. METHODS: The clinical and laboratory data of children who underwent LDLT from June 2010 to September 2012 in First Center Hospital in Tianjin, China, were retrospectively included in the study. Intrahepatic HBV DNA in donors and recipients was quantified by realtime polymerase chain reaction using DNA extracted from formalin-fixed, paraffin-embedded tissues. RESULTS: Between June 2010 to September 2012, 32 consecutive pediatric patients underwent LDLT in our institute. Thirty LDLT patients(13 girls and 17 boys) were followed up for a median of 15 mo, of whom 53.3%(16/30) were hepatitis B core antibody(HBcAb) positive and 36.7%(11/30) were hepatitis B surface antibody(HBsAb)/HBcAb positive before transplantation. Sixteen of the children received HBcAb-positive allografts, and 43.7%(7/16) of the grafts were found to be intrahepatic HBV DNA positive. De novo HBV infection developed in 16.1%(5/30) of the children within a median of 11 mo after transplantation. All five of the HBV-infected children had received HBcAb-positive allografts, four of which were intrahepatic HBV DNA positive. Two of the children developed de novo HBV infection despite the preoperative presence of both HBsAb and HBcAb CONCLUSION: In pediatric recipients, positive intrahepatic HBV DNA in allografts could be a risk factor for de novo HBV infection from HBcAb-positive allografts. HBsAb/HBcAb positivity in pediatric LDLT patients before transplantation exhibited only weak effectiveness in protecting them against de novo HBV infection from HBcAb-positive allografts.Wei Rao Man Xie Tao Yang Jian-Jun Zhang Wei Gao Yong-Lin Deng Hong Zheng Cheng Pan Yi-He Liu Zhong-Yang Shen 2014World Journal of Gastroenterology2014,20,36:4
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