| 1 | Necessity and indications of invasive treatment for Budd-Chiari syndrome显示文摘BACKGROUND:The development of collaterals in Budd-Chiari syndrome has been described and these collaterals play an important role in the presentation of this disease.These collaterals are diagnostic and their use in management strategy has never been evaluated.This study aimed to investigate the indications,feasibility and necessity of invasive treatment for patients with Budd-Chiari syndrome and to determine whether such a strategy is necessary for optimal management.METHODS:Twenty-nine patients who had been treated at our unit were enrolled in this study.Based on physical and biochemical examination,and hemodynamic compensation by collaterals,18 patients underwent radiological intervention (group A),while the other 11 had no invasive treatment (group B).The related hemodynamic parameters were acquired when percutaneous angiography was performed.RESULTS:In group A,all patients underwent successfully inferior vena cava (IVC) balloon angioplasty with or without stenting.Four patients also underwent hepatic vein angioplasty.In these patients,the mean IVC pressure before and after treatment was statistically different (29.3±9.2 vs 15.1±4.6 mmHg,P<0.01).The mean IVC pressure was much lower in group B than in group A (12.9±2.4 vs 29.3±9.2 mmHg,P<0.01),but there was no difference from that of the patients after radiological treatment (12.9±2.4 vs 15.1±4.6 mmHg,P>0.05).Median follow-up was 32.3 months (mean 21.3 months;range 3-61 months).In the course of follow-up,the patients in group A survived with good systemic status except for re-stenosis in one patient who underwent re-canalization of the IVC.In group B,10 patients had good systemic status except one patient who had a meso-caval shunt because of deterioration.CONCLUSIONS:The rationale of 'early diagnosis and early treatment' is not suitable for all patients with Budd-Chiari syndrome.Satisfactory survival can be achieved in some patients without invasive treatment,who are completely compensated by rich collaterals.Nonetheless,a positive treatment procedure should be performed if the patient's situation worsens in the course of regular follow-up. | Department of General Surgery (Fu Y,Sun YL,Ma XX,Xu PQ,Feng LS,Tang Z and Luo CH),Institute of Hepatic Vascular Disease (Sun YL),Department of Radiological Intervention (Guan S and Wang ZW),First Affiliated Hospital,Zhengzhou University School of Medicine,Zhengzhou 450052,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 10 |
| 2 | B超引导下肝静脉型布加综合征的介入治疗体会显示文摘目的探讨B超引导下经皮肝穿联合经颈内静脉入路肝静脉扩张成形术治疗肝静脉型布加综合征的方法和疗效。方法对于确诊肝静脉型布加综合征的17例患者采用B超引导下经皮肝穿肝静脉造影,经颈内静脉入路肝静脉球囊扩张成形术治疗,其中扩张肝右静脉8例,肝中静脉5例,副肝静脉4例,未放置支架。结果全组病例无手术死亡,全部痊愈出院,出院时腹水消退,脾脏明显缩小。随访524个月,2例复发,右肝静脉狭窄至2 mm,再次球囊扩张后痊愈。结论重视肝静脉型布加综合征的诊断,采用B超引导下经皮肝穿联合经颈内静脉入路肝静脉扩张成形术治疗肝静脉型布加综合征具有成功率高、肝脏损伤小、创伤小。 | 陈世远 高涌 聂中林 孙医学 | 2011 | 中华全科医学2011，9，5： | 4 |
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