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| 1 | Immunological Effects of Total Flavones from Leaves of Choerospondias axillaris on Mice显示文摘Objective To investigate the effect of total flavones from the leaves of Choerospondias axillaris(TFLCA) on the immune function of normal mice and to provide the experimental basis for the reasonable application of C. axillaris.Methods The carbon clearance method, cutaneous delayed hypersensitivity reaction method, serum hemolysin method, and index of immune organs were used to study the effect of TFLCA on the immune function of mice. Results TFLCA could enhance the phagocytic function of mononuclear macrophage and the cutaneous delayed hypersensitivity reaction of mice, and increase the content of hemolysin antibody and the thymus index in mice.Conclusion TFLCA could improve the celiac macrophage activity and specific immunity of mice, and TFLCA,consisting with the total flavones of Choerospondiatis Fructus(TFCF), has the effect on the immune function of mice.So both TFLCA and TFCF have the regulatory effects on the immune function of mice. | LIU Xin-yuan YANG Yu-mei HAN Feng ZHANG Hao-nan DU Jian-xi HAO Xin-min | 2013 | Chinese Herbal Medicines2013，5，2： | 3 |
| 2 | Research on Characteristic Manifestations of Xiaochaihu Decoction Based on Association Rules Mining显示文摘Objective: The aim of this study is to explore the characteristic manifestations and contraindications of Xiaochaihu decoction(XD [It also stands for all the seven herbs in XD]) syndrome and to clarify the principle of using XD. Methods: By searching on the Encyclopedia of Traditional Chinese Medicine, 254 cases whose symptoms were relieved by XD and 48 cases who misused XD in ancient time were selected. Moreover, they are divided into two groups. Microsoft Excel 2016 was used as a storage tool. These two groups of cases were all treated with XD because of their similar manifestations, but therapeutic efficacies are reverse. The manifestations mislead doctors should be selected out to clarify the indications of using XD. Thus, the professional data mining software RapidMiner was used as a platform to do the frequent statistic and to create association rules between manifestations and herbs of both groups, respectively. After comparing the results of two groups, we can make a conclusion. Results: The characteristics of XD syndrome are alternative chills and fever, hypochondriac pain, and inflammatory swelling and pain(ear or breast). When any of these manifestations occur, XD can be used. Wiry pulse paired with alternative chills and fever, headache, thirst, or hypochondriac pain is also regarded as the indications of using XD. XD should not treat for fever paired with other manifestations, such as headache, delirium, or aversion to cold. In addition, the manifestations with high concurrence frequency do not mean the high correlation. Moreover, only according to the frequency, statistics cannot make correct conclusions. Conclusions:(1) XD is more fit for the excess syndrome such as excess fire in the liver or gallbladder meridians.(2) The medical records in which the XD is misused are also worth analyzing.(3) Association rules cannot be substituted with frequency statistics. | Li-Ying Zhu Chun-Hua Jia Eunhee Park | 2019 | World Journal of Traditional Chinese Medicine2019，5，1： | 0 |
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