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| 1 | 热处理豆粕饲喂生长猪的氨基酸消化率显示文摘为测定热处理对豆粕(SBM)表观回肠消化率和标准回肠消化率(SID)的影响,本试验将常规去壳豆粕(48.5%蛋白)分成4组,一份未经额外热处理,一份在125℃下高压蒸汽处理15 min,一份在125℃下高压蒸汽处理30 min,另一份在125℃下烘箱烘干30 min。制定四种豆粕-玉米淀粉型日粮配方,且每个配方只能使用上述四种豆粕中的一种,作为每种日粮中唯一氨基酸来源。用无氮日粮配方来估算基础内源性氨基酸损失。分别在初始体重为(25.3±2.0)kg的10头阉公猪回肠末端安装一个T-型瘘管。采用5×5拉丁方设计法,将试验猪分成5个日粮处理组,5个重复处理周期。每个处理周期持续7 d,在第6天和第7天收集回肠食糜。试验结果表明,随着高压蒸汽处理时间(0~30 min)的延长,蛋白质和所有氨基酸的表观回肠消化率和标准回肠消化率呈线性降低(P<0.01)。糠氨酸含量和豆粕样品的颜色表明高压蒸汽处理导致豆粕产生美拉德反应。然而,125℃烘箱干燥30min并未改变豆粕中蛋白和氨基酸标准回肠消化率,也没有改变SBM的糠氨酸含量(P>0.10),且烘箱处理的样品颜色表明该样品并未受到热处理破坏。总之,热蒸汽处理时间从0 min增至30 min,高压蒸汽处理豆粕的氨基酸消化率呈线性降低,降低原因很可能是由于125℃高压蒸汽处理导致豆粕产生美拉德反应。 | González-Vega J C Kim B G Htoo J K Lemme A Stein H H | 2015 | 中国饲料2015,,24: | 8 |
| 2 | Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer显示文摘gonadal 睾丸激素合成的抑制首先代表标准为变形前列腺癌症的治疗的线治疗。在得阉割抵抗的前列腺癌症(CRPC ) 的病人的多数,然而,通过自己在肾上腺或在肿瘤以内生产的雄激素检测雄激素受体(AR ) 的坚持的激活是可能的。Abiraterone 醋酸盐作为 17 α 与活动作为双功能的细胞色素 P450 酶 CYP17 的一个不可逆的禁止者被开发; -hydroxylase 和 17,20-lyase。CYP17 为从胆固醇的 nongonadal 雄激素的生产是必要的。基于与 abiraterone 和泼尼松对泼尼松在全面幸存(OS ) 显示出重要改进的阶段 III 试用,在 2011 的 abiraterone 的规章的赞同代表了指向 AR 为与 CRPC 在人改进结果是必要的原则的证明。 17 α 的抑制;由 abiraterone 的 -hydroxylase 由于垂体的调停皮质醇的抑制的损失导致在上游的 mineralocorticoids 的累积促肾上腺皮质的荷尔蒙( ACTH ),为 17,20-lyase 为 CYP17 禁止者的开发向一个基本原理提供增加的特性( orteronel , galeterone 和 VT-464 )没有外长的 corticosteroids ,那能潜在地被管理。在这篇文章,我们考察 abiraterone 和另外的 CYP17 禁止者的发展;有 abiraterone 的最近的研究在 quality-of-life,反应的潜在的早预言者,并且关于另外的代理人的 abiraterone 的最佳的定序上通知我们的理解象药效果那样的临床的参数;并且提供卓见进抵抗机制给导致临床的试用,药联合设计了延长 abiraterone 利益或恢复 abiraterone 活动的 CYP17 禁止者的翻译研究结果。 | Mark N Stein | 2014 | Asian Journal of Andrology2014,16,3: | 3 |
| 3 | Formation of macrodefects in SiC 显示文摘 | STEIN R A | 1993 | Physica B1993,185,: | 2 |
| 4 | Comparison of the efficacy and safety of rosuvastatin versus atorvastatin , simvastatin , and pravastatin across doses (STELLAR * * STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)显示文摘 | Peter H Jones Michael H Davidson Evan A Stein Harold E Bays James M McKenney Elinor Miller Valerie A Cain James W Blasetto | 2003 | The American Journal of Cardiology2003,,2: | 2 |
| 5 | Formation, derivatization and applications of bacterial cellulose 显示文摘 | Geyer U Heinze T Stein A | 1994 | Int J Biol Macromol1994,16,6: | 1 |
| 6 | Avian adipose lipoprotein lipase: cDNA sequence and reciprocal regulation of mRNA levels in adipose and heart显示文摘 | Cooper D A Stein J C Strieleman P J | 1989 | Biochim Biophys Acta1989,1008,1: | 1 |
| 7 | Banks as liquidity pr oviders: An explanation for the co-existence of lending and deposit taking 显示文摘 | Kashy A K Rajan R Stein J C | 2002 | Journal of Finance2002,57,1: | 1 |
| 8 | Constrained optimization of spatial sampling using continuous simulated annealing 显示文摘 | Van Groenigen J W Stein A | 1998 | Journal of Environmental Quality1998,27,5: | 1 |
| 9 | Chemistry of Grain Boundaries and Its Re- lation to Intergranular Corrosion of Austenitlc Stainless Steel 显示文摘 | Joshi A Stein D F | 1972 | Corrosion1972,28,9: | 1 |
| 10 | Pneumoniae of Swines Cost and Value of Control显示文摘 | Leman A D T Stein B Straw H D Hilley | 1982 | Mod Vet Pract1982,63,: | 1 |
| 11 | Structure and properties of ovalbumin显示文摘 | HUNTINGTON J A STEIN P E | 2001 | Journal of Chromatography B2001,756,: | 1 |
| 12 | Hybrid thin wire external fixation : an effective, mini- mally invasive,modular surgical tool for the stabilization of periarticular fractures 显示文摘 | Lemer A Stein H | 2004 | Orthopedics2004,27,2: | 1 |
| 13 | Assessing the representativeness of the wet tropics of Queensland World heritage property显示文摘 | Mackey B G Nix H A Stein J A | 1989 | Biological Conservation1989,50,: | 1 |
| 14 | Sentinel lymph node mapping in gastric and esophageal carcinomas显示文摘 | Burian M Stein HJ Sendler A | 2004 | Chirurg2004,75,8: | 1 |
| 15 | APRIL modulates B and T cell immunity显示文摘 | STEIN J V LOPEZ-FRAGA M ELUSTONDO F A | 2002 | J Clin Invest2002,109,12: | 1 |
| 16 | Computational analysis of stall and separation control in compressors 显示文摘 | STEIN A NIAZI S SANKAR L | 2000 | Journal of Propulsion and Power2000,16,1: | 1 |
| 17 | Struc-ture of the FoxMl DNA-recognition domain bound to a pro-moter sequence显示文摘 | Little D R Alvarez Fernandez M Stein A | 2010 | Nucl Acids Res2010,38,13: | 1 |
| 18 | ESMO Consensus Guidelines for management of patients with colon and rectal cancer, a personalized approach to 'clinical decision making 显示文摘 | Schmoll HJ Van Cutsem E Stein A | 2012 | Ann 0ncol2012,23,10: | 1 |
| 19 | High serum and cerebrospinal fluid Ca/Mg ratio in recently hospitalized acutely depressed patients 显示文摘 | Levine J Stein D Rapoport A | 1999 | Neuropsychobiology1999,39,2: | 1 |
| 20 | COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease显示文摘 | Wayne A Ray C Michael Stein James R Daugherty Kathi Hall Patrick G Arbogast Marie R Griffin | 2002 | The Lancet2002,,9339: | 1 |