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| 1 | Randomized controlled trial of bipolar diathermy vs ultrasonic scalpel for closed hemorrhoidectomy显示文摘AIM:To compare hemorrhoidectomy with a bipolar electrothermal device or hemorrhoidectomy using an ultrasonically activated scalpel.METHODS:Sixty patients with grade Ⅲ or Ⅳ hemorrhoids were prospectively randomized to undergo closed hemorrhoidectomy assisted by bipolar diathermy(group 1) or hemorrhoidectomy with the ultrasonic scalpel(group 2).Operative data were recorded,and patients were followed at 1,3,and 6 wk to evaluate complications.Independent assessors were assigned to obtain postoperative pain scores,oral analgesic requirement and satisfaction scores.RESULTS:Reduced intraoperative blood loss median 0.9 mL(95% CI:0.8-3.7) vs 4.6 mL(95% CI:3.8-7.0),P = 0.001 and a short operating time median 16(95% CI:14.6-18.2) min vs 31(95% CI:28.1-35.3) min,P < 0.0001 was observed in group 1 compared with group 2.There was a trend towards lower postoperative pain scores on day 1 group 1 median 2(95% CI:1.8-3.5) vs group 2 median 3(95% CI:2.6-4.2),P = 0.135.Reduced oral analgesic requirement during postoperative 24 h after operation median 1(95% CI:0.4-0.9) tablet vs 1(95% CI:0.9-1.3) tablet,P = 0.006 was observed in group 1 compared with group 2.There was no difference between the two groups in the degree of patient satisfaction or number of postoperative complications.CONCLUSION:Bipolar diathermy hemorrhoidectomy is quick and bloodless and,although as painful as closed hemorrhoidectomy with the ultrasonic scalpel,is associated with a reduced analgesic requirement immediately after operation. | Akira Tsunoda Haruki Sada Takuya Sugimoto Nobuyasu Kano Mariko Kawana Tadanori Sasaki Hideki Hashimoto | 2011 | World Journal of Gastrointestinal Surgery2011，3，10： | 6 |
| 2 | Clinical usefulness of endoscopic ultrasonography for the evaluation of ulcerative colitis-associated tumors显示文摘AIM:To evaluate the clinical usefulness of endoscopic ultrasonography(EUS) for the diagnosis of the invasion depth of ulcerative colitis-associated tumors.METHODS:The study group comprised 13 patients with 16 ulcerative colitis(UC)-associated tumors for which the depth of invasion was preoperatively estimated by EUS.The lesions were then resected endoscopically or by surgical colectomy and were examined histopathologically.The mean age of the subjects was 48.2 ± 17.1 years,and the mean duration of UC was 15.8 ± 8.3 years.Two lesions were treated by endoscopic resection and the other 14 lesions by surgical colectomy.The depth of invasion of UCassociated tumors was estimated by EUS using an ultrasonic probe and was evaluated on the basis of the deepest layer with narrowing or rupture of the colonic wall.RESULTS:The diagnosis of UC-associated tumors by EUS was carcinoma for 13 lesions and dysplasia for 3 lesions.The invasion depth of the carcinomas was intramucosal for 8 lesions,submucosal for 2,the muscularis propria for 2,and subserosal for 1.Eleven(69%) of the 16 lesions arose in the rectum.The macroscopic appearance was the laterally spreading tumor-non-granular type for 4 lesions,sessile type for 4,laterally spreading tumor-granular type for 3,semipedunculated type(Isp) for 2,type 1 for 2,and type 3 for 1.The depth of invasion was correctly estimated by EUS for 15 lesions(94%) but was misdiagnosed as intramucosal for 1 carcinoma with high-grade submucosal invasion.The 2 lesions treated by endoscopic resection were intramucosal carcinoma and dysplasia,and both were diagnosed as intramucosal lesions by EUS.CONCLUSION:EUS provides a good estimation of the invasion depth of UC-associated tumors and may thus facilitate the selection of treatment. | Kiyonori Kobayashi Kana Kawagishi Shouhei Ooka Kaoru Yokoyama Miwa Sada Wasaburo Koizumi | 2015 | World Journal of Gastroenterology2015，21，9： | 5 |
| 3 | Decrease in Serum Amyloid a Protein Levels Following Three-month Stays in Negatively Charged Particle-dominant Indoor Air Conditions显示文摘Objective The changes in serum adipokines and cytokines related to oxidative stress were examined during 3 months ‘Off to On' and ‘On to Off' periods using negatively charged particle-dominant indoor air conditions(NCPDIAC).Methods Seven volunteers participated in the study,which included ‘OFF to 3 months ON' periods(ON trials) for a total of 16 times,and ‘ON to 3 months OFF'(OFF trials) periods for a total of 13 times.Results With the exception of one case,serum amyloid A(SAA) levels decreased significantly during the ON trials.Conclusion Considering that SAA is an acute phase reactive protein such as C reactive protein(CRP),this observed decrease might indicate the prevention of cardiovascular and atherosclerotic changes,since an increase in high-sensitive CRP is associated with the subsequent detection of these events. | Suni Lee Shoko Yamamoto Yasumitsu Nishimura Hidenori Matsuzaki Kei Yoshitome Tamayo Hatayama Miho Ikeda YU Min Nagisa Sada Naoko Kumagai-Takei Takemi Otsuki | 2018 | Biomedical and Environmental Sciences2018，31，5： | 5 |
| 4 | 食品杀菌技术的现状及未来发展趋势显示文摘本文综述了食品杀菌技术的现状,对液体、固体食品的杀菌技术做了详细解释,并对新的杀菌技术做了说明。 | Sada Morihiro | 2018 | 中国洗涤用品工业2018，，11： | 2 |
| 5 | Tuning of fractional PID controllers with Ziegler-Nichols type rules显示文摘 | Valerio D Sada Costa J | 2006 | Signal Processing2006，86，10： | 1 |
| 6 | Anal function af- ter ligation of the intersphincteric fistula tract 显示文摘 | Tsunoda A Sada H Sugimoto T | 2013 | Dis Colon Rectum2013，56，7： | 1 |
| 7 | Good response of membranous lupus nephritis to tacrolimus显示文摘 | MARUYAMA M YAMASAKI Y SADA K | 2006 | Clini Nephrol2006，65，4： | 1 |
| 8 | Amygdalar hyperactivity, a fear-related link between panic disorder and mesiotemporal epilepsy 显示文摘 | GEREZ M SADA A TELLO A | 2011 | Clin EEG Neurosci2011，42，： | 1 |
| 9 | Numerical calculation of flow and stack-gas concentration fluctuation around a cubical building显示文摘 | SADA K SATO A | 2002 | Atmospheric Environment2002，36，35： | 1 |
| 10 | Evaluation of lipoarabinomannan for the serological diagnosis of tuberculosis显示文摘 | Brennan P J Herrera T | 1990 | J Clm Microbiol1990，28，： | 1 |
| 11 | Pharmacology of CS-866,a novel nonpeptide angiotension Ⅱ receptor antagonist显示文摘 | Mizuno M Sada T lkeda M | 1995 | Eur J Pharmacol1995，285，2： | 1 |
| 12 | Meta-analysis of the efficacy of aripiprazole in schizophrenia显示文摘 | Lieberman J Carson WH Sada AR | 2002 | Int J Neuropsychopharmcol2002，，： | 1 |
| 13 | Good response of membranous lupus nephritis to tacrolimus显示文摘 | Maruyama M Yamasaki Y Sada K | 2006 | Clin Nephrol2006，65，4： | 1 |
| 14 | Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells显示文摘 | Sada K Miah SM Maeno K | 2002 | Blood2002，100，6： | 1 |
| 15 | 显示文摘 | Sadek MI Sada E Toessi I | 1998 | Am J Respir Cell Mol Biol1998，19，3： | 1 |
| 16 | Factor X deficiency: An uncommon presentation of AL amyloidosis显示文摘 | Katsuyama T Sada KE Katayama A | 2012 | Ups J Med Sci2012，117，4： | 1 |
| 17 | Structure and function of Sykproteintyrosine kinase显示文摘 | Sada K Takano T Yanagi S | 2001 | J Biochem(Tokyo)2001，130，： | 1 |
| 18 | Antimierobial peptides in the innate immunity of infectious diseases 显示文摘 | Rivaa-Santiago B Sada E Hemandez-Pando R | 2006 | Salud Publiea Mex2006，48，1： | 1 |
| 19 | Chemical absorption in a bubble column loading concentrated slurry 显示文摘 | Sada E Kumazawa H Lee C H | 1983 | Chemical Engineering Science1983，38，12： | 1 |
| 20 | Good response of membranous lupus nephritis to tacrolimus 显示文摘 | MARUYAMA M YAMASAKI Y SADA K | 2006 | Clin Nephrol2006，65，4： | 1 |
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