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| 1 | 桡骨远端骨折掌侧钢板固定后尺骨茎突骨折是否需要固定?显示文摘背景:尺骨茎突骨折常伴发于桡骨远端骨折。本研究的目的是确定桡骨远端骨折牢固内固定后伴发的尺骨茎突骨折对腕关节功能或远期下尺桡关节不稳定的发展是否有影响。方法:138例不稳定的桡骨远端骨折手术治疗病例纳入本研究。手术过程中伴发的尺骨茎突骨折未进行内固定。患者尺骨茎突骨折被分为未骨折组、非基底部骨折组和基底部骨折组,根据受伤时尺骨茎突骨折移位程度分为未骨折组、轻度移位组(≤2mm)和明显移位组(〉2mm)。术后评估包括握力和腕关节活动范围的测量;改良Mayo腕关节评分和臂、肩、手不稳定(DASH)评分系统,以及在平均术后19个月的测试下尺桡关节的不稳定。结果:138例中76例(55%)存在尺骨茎突骨折。47例(62%)为尺骨茎突非基底部骨折,29例(38%)为尺骨茎突基底部骨折。34例(45%)轻度移位,42例(55%)明显移位(〉2mm)。我们没有发现尺骨茎突骨折位置或移位程度与腕关节功能有显著相关性。2例腕关节(1.4%)出现下尺桡关节慢性不稳。结论:桡骨远端骨折稳定内固定后伴发的尺骨茎突骨折对腕关节功能或下尺桡关节的稳定性没有明显的不利影响。 | Jae Kwang Kim Young-Do Koh Nam-Hoon Do 朱丹杰(译) 夏冰(译) | 2010 | 中华骨科杂志2010，30，6： | 42 |
| 2 | 经桡动脉穿刺的冠状动脉介入治疗显示文摘目的 探讨经桡动脉穿刺行冠状动脉介入治疗的可行性和安全性。方法 116例冠心病患者 (男 96例 ,女 2 0例 ,平均年龄 5 7 44± 9 40岁 )经桡动脉穿刺行冠状动脉介入治疗。结果 5例桡动脉穿刺失败改行股动脉穿刺 ,2例桡动脉穿刺虽成功但试行球囊扩张失败 ,其余患者均取得穿刺和介入治疗成功。共扩张病变血管 135支 (前降支 6 9支 ,回旋支 2 6支 ,右冠状动脉 39支 ,静脉桥血管1支 ) ,治疗病变 148处 (A型 15处 ,B型 10 6处 ,C型 2 7处 )。 98例患者的 10 5支血管植入支架共 110个 ,1例行旋磨术 ,1例行冠状动脉内超声检查。 2 5例患者术中须更换导引导管。术后穿刺局部大量出血需输血者 1例 ,局部较大血肿 2例 ,肘动脉分支穿孔 1例。结论 经桡动脉穿刺行冠状动脉介入治疗在临床上可行 ,但穿刺较困难 ,导引导管支撑力较差 ,应警惕局部血管损伤的可能。 | 洪涛 Koh Tian Hai Charles Chan Lim Yean-Leng | 2002 | 中国介入心脏病学杂志2002，10，3： | 39 |
| 3 | Neuroinflammation in neurodegenerative disorders:the roles of microglia and astrocytes显示文摘Neuroinflammation is associated with neurodegenerative diseases,such as Alzheimer's disease,Parkinson's disease,ancamyotrophic lateral sclerosis.Microglia and astrocytes are key regulators of inflammatory responses in the central nervous system.The activation of microglia and astrocytes is heterogeneous and traditionally categorized as neurotoxi(M1-phenotype microglia and A1-phenotype astrocytes)or neuroprotective(M2-phenotype microglia and A2-phenotype astrocytes).However,this dichotomized classification may not reflect the various phenotypes of microgliaand astrocytes.The relationship between these activated glial cells is also very complicated,and the phenotypic distribution can change,based on the progression of neurodegenerative diseases.A better understanding of the rolesof microglia and astrocytes in neurodegenerative diseases is essential for developing effective therapies.In this review,we discuss the roles of inflammatory response in neurodegenerative diseases,focusing on the contributions of microglia and astrocytes and their relationship.In addition,we discuss biomarkers to measure neuroinflammation andstudies on therapeutic drugs that can modulate neuroinflammation. | Hyuk Sung Kwon Seong-Ho Koh | 2020 | Translational Neurodegeneration2020，9，4： | 40 |
| 4 | 中国东北地区水稻主要栽培品种的遗传多样性分析显示文摘利用68对SSR引物对91份粳稻品种进行了遗传多样性分析。研究结果共检测到293个等位基因,平均4.3个;平均多态信息含量(PIC)为0.313,变动范围为0.022~0.825。RM333和RM206的等位基因数最多,分别为14、10;且PIC也最高,分别为0.825、0.805。聚类和群体差异分析结果表明,东北三省水稻品种的遗传基础狭窄。黑龙江省和吉林省、黑龙江省和日本、吉林省和日本的水稻品种间遗传距离都很小,分别为0.083、0.084、0.090,而辽宁省与吉林省、黑龙江省的水稻品种遗传基础有一些差异。9个地理来源的品种聚类结果,可分为5个大类群,黑龙江省、吉林省、日本和韩国形成第Ⅰ类群;北京和辽宁省归为第Ⅱ类群;中国台湾、云南省、美国分别为第Ⅲ、第Ⅳ和第Ⅴ类群。东北三省是重要的粳稻生产基地,但遗传基础非常狭窄,要克服遗传脆弱性应从地理位置较远的国家或地区收集更丰富的遗传资源。 | 玄英实 姜文洙 刘宪虎 程正海 Hee-Jong Koh 元东林 | 2010 | 植物遗传资源学报2010，11，2： | 27 |
| 5 | 基于二维磁特性测量的电工钢片矢量磁滞模型显示文摘提出一种模拟电工钢片复杂磁特性的矢量磁滞模型。该模型考虑频率、磁化历史等因素对磁滞特性的影响,模型中磁滞系数与磁阻系数的确定是基于双激励二维磁特性测量实验获得的,在实验中通过对磁通密度变化轨迹的控制实现对磁场强度波形的测量。所提出的模型既避免了传统磁滞模型数学表达的复杂性,又提高了模拟的准确度,更适用于工程应用。通过与传统模型及实验测量结果的比较,证明了所提出的模型能更有效、更准确地模拟电工钢片的复杂磁特性。 | 张艳丽 何厚键 谢德馨 KOH Chang-seop | 2010 | 中国电机工程学报2010，30，3： | 25 |
| 6 | 移动车辆荷载作用下大跨径连续梁桥动力响应研究显示文摘针对移动车辆荷载作用下公路桥梁动力性能设计与评价方法不足的问题,以依兰松花江公路大桥为例,运用自编程序,分析不同车辆荷载工况下桥梁冲击系数与振动加速度等动力响应指标的变化规律。结果表明,冲击系数随车辆纵向间距与车速的变化规律一致,均呈波动上升趋势;多车道时,若桥面不平整度沿横向变化不明显则冲击系数与车道数基本无关;大跨径桥梁不同部位的冲击系数有别,现行规范所采用单一断面的冲击系数计算全桥设计荷载方法的合理性值得商榷;在固定车距下,冲击系数随着加载效率的增大而呈下降趋势;振动加速度与冲击系数具有高度相关性。本文所得结论为移动车辆荷载作用下桥梁动力性能设计与评价提供了一定的依据。 | 王宗林 高庆飞 KOH Chan Ghee 陈闯 郭斌强 | 2015 | 桥梁建设2015，45，2： | 21 |
| 7 | Predictive findings forHelicobacter pylori-uninfected, -infected and -eradicated gastric mucosa: Validation study显示文摘AIM:To validate the usefulness of screening endoscopy findings for predictingHelicobacter pylori (H. pylori) infection status. METHODS:H. pylori infection status was determined by histology, serology, and the urea breast test in 77 consecutive patients who underwent upper endoscopy. Based on the findings, patients were categorized as H. pylori -uninfected, -infected, or -eradicated cases. Using six photos of certain sites in the stomach per case, we determined the presence or absence of the following endoscopic findings:regular arrangement of collecting venules (RAC), linear erythema, hemorrhage, fundic gland polyp (FGP), atrophic change, rugal hyperplasia, edema, spotty erythema, exudate, xanthoma, and mottled patchy erythema (MPE). The diagnostic odds ratio (DOR) and inter-observer agreement (Kappa value) for these 11 endoscopic findings used in the determination of H. pylori infection status were calculated. RESULTS:Of the 77 patients [32 men and 45 women; mean age (SD), 39.7 (13.4) years] assessed, 28 were H. pylori uninfected, 28 were infected, and 21 were eradicated. DOR values were significantly high (< 0.05) for the following H. pylori cases:uninfected cases with RAC (11.5), linear erythema (24.5), hemorrhage (4.1), and FGP (34.5); for infected cases with atrophic change (8.67), rugal hyperplasia (15.8), edema (14.2), spotty erythema (11.5), and exudate (3.52); and for eradicated cases with atrophic change (32.4) and MPE (103.0). Kappa values were excellent for FGP (0.93), good for RAC (0.63), hemorrhage (0.79), atrophic change (0.74), and MPE (0.75), moderate for linear erythema (0.51), rugal hyperplasia (0.49), edema (0.58), spotty erythema (0.47), and exudate (0.46), and poor for xanthoma (0.19). CONCLUSION:The endoscopic findings of RAC, hemorrhage, FGP, atrophic change, and MPE will be useful for predicting H. pylori infection status. | Kazuhiro Watanabe Naoyoshi Nagata Ryo Nakashima Etsuko Furuhata Takuro Shimbo Masao Kobayakawa Toshiyuki Sakurai Koh Imbe Ryota Niikura Chizu Yokoi Junichi Akiyama Naomi Uemura | 2013 | World Journal of Gastroenterology2013，19，27： | 17 |
| 8 | 欧美国家胃癌手术并发症的诊断标准及风险评估显示文摘术后并发症是手术质量和安全控制的重要标准,然而由于国内外对并发症的认识、诊断缺乏共识,导致并发症的登记问题一直备受争议。为此,我们通过4个电话会议.了解西方国家单中心数据登记系统、国家数据登记系统以及国际多中心临床登记系统的实际操作情况。其中采访了澳大利亚皇家艾尔弗莱德王子医院消化道外科的Koh教授,了解其单中心的经验;同时还分别采访了STOMACH研究的vander Wielen医生和IMIGASTIC国际研究小组的Desiderio医生,以及荷兰上消化道癌国家级数据库的Wijnhoven教授.以了解其多中心研究情况。我们采访的问题主要包括以下几个方面:哪些并发症需要上报。上报并发症的定义.由谁完成并发症登记以及如何对并发症进行评估。在相关数据库中,DUCA和IMIGASTRIC给出了主要并发症的定义.其中DUCA的定义是在国际专家们经过4年商讨及共识会议后得出的LOW分类标准的基础上进一步完善的。然而,没有任何一个登记系统强制要求在参与中心以及外科医生实行统一诊断标准。相反,所有的登记系统均要求详细记录并发症的诊断策略并使用Clavien.Dindo评分系统完成并发症分类。大多数的数据登记是由外科医生或数据管理员在患者住院期间、或者出院后立即完成。登记系统中数据的质量控制由相关研究人员或第三方审查完成。从西方的经验我们可以看到,在不同的中心实现并发症诊断的标准化是一个艰巨的任务,需要花费大量的人力、物力和财力。目前,各中心在登记并发症的同时应记录诊断方法及相应的干预措施,以便后续各中心根据Clavien—Dindo分级标准对并发症进行分级。该分级系统现已被中西方大多数中心采纳.可作为未来胃癌术后并发症的标准评估体系。 | 吴舟桥 王琦 石晋瑶 Cherry Koh Desiderio Jacopo 李子禹 季加孚 | 2017 | 中华胃肠外科杂志2017，20，2： | 17 |
| 9 | Tenofovir rescue therapy for chronic hepatitis B patients after multiple treatment failures显示文摘AIM:To evaluate the efficacy and safety of tenofovir disoproxil fumarate(TDF) for chronic hepatitis B(CHB) patients after multiple failures.METHODS:A total of 29 CHB patients who had a suboptimal response or developed resistance to two or more previous nucleoside/nucleotide analogue(NA) treatments were included.Study subjects were treated with TDF alone(n = 13) or in combination with lamivudine(LAM,n = 12) or entecavir(ETV,n = 4) for ≥ 6 mo.Complete virologic response(CVR) was defined as an achievement of serum hepatitis B virus(HBV) DNA level ≤ 60 IU/mL by real-time polymerase chain reaction method during treatment.Safety assessment was based on serum creatinine and phosphorus level.Eleven patients had histories of LAM and adefovir dipivoxil(ADV) treatment and 18 patients were exposed to LAM,ADV,and ETV.Twenty-seven patients(93.1%) were hepatitis B e antigen(HBeAg) positive and the mean value of the baseline serum HBV DNA level was 5.5 log IU/mL ± 1.7 log IU/mL.The median treatment duration was 16 mo(range 7 to 29 mo).RESULTS:All the patients had been treated with LAM and developed genotypic and phenotypic resistance to it.Resistance to ADV was present in 7 patients and 10 subjects had a resistance to ETV.One patient had a resistance to both ADV and ETV.The cumulative probabilities of CVR at 12 and 24 mo of TDF containing treatment regimen calculated by the Kaplan Meier method were 86.2% and 96.6%,respectively.Although one patient failed to achieve CVR,serum HBV DNA level decreased by 3.9 log IU/mL from the baseline and the last serum HBV DNA level during treatment was 85 IU/mL,achieving near CVR.No patients in this study showed viral breakthrough or primary non-response during the follow-up period.The cumulative probability of HBeAg clearance in the 27 HBeAg positive patients was 7.4%,12%,and 27% at 6,12,and 18 mo of treatment,respectively.Treatment efficacy of TDF containing regimen was not statistically different according to the presence of specific HBV mutations.History of prior exposure to specific antiviral agents did not make a difference to treatment outcome.Treatment efficacy of TDF was not affected by combination therapy with LAM or ETV.No patient developed renal toxicity and no cases of hypophosphatemia associated with TDF therapy were observed.There were no other adverse events related to TDF therapy observed in the study subjects.CONCLUSION:TDF can be an effective and safe rescue therapy in CHB patients after multiple NA therapy failures. | Yu Jin Kim Dong Hyun Sinn Geum-Youn Gwak Moon Seok Choi Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo Joon Hyeok Lee | 2012 | World Journal of Gastroenterology2012，18，47： | 16 |
| 10 | Perfusion magnetic resonance imaging of the liver显示文摘Perfusion magnetic resonance imaging (MRI) studies quantify the microcirculatory status of liver parenchyma and liver lesions, and can be used for the detection of liver metastases, assessing the effectiveness of antiangiogenic therapy, evaluating tumor viability after anticancer therapy or ablation, and diagnosis of liver cirrhosis and its severity. In this review, we discuss the basic concepts of perfusion MRI using tracer kinetic modeling, the common kinetic models applied for analyses, the MR scanning techniques, methods of data processing, and evidence that supports its use from published clinical and research studies. Technical standardization and further studies will help to establish and validate perfusion MRI as a clinical imaging modality. | Choon Hua Thng Tong San Koh David J Collins Dow Mu Koh | 2010 | World Journal of Gastroenterology2010，16，13： | 15 |
| 11 | 考虑硅钢片二维矢量磁特性的复数E&S模型显示文摘电工材料电磁特性的精细模拟是决定电工装备电磁场分析与损耗计算正确与否的关键因素之一。提出了一种能够描述硅钢片二维矢量磁特性的复数E&S模型,该模型既能够考虑交变磁化,又能够考虑旋转磁化的影响。基于硅钢片二维磁特性测量实验,提出了利用1个周期内磁能密度平均值计算模型中有效磁阻系数,利用磁滞损耗密度计算有效磁滞系数的方法。推导了结合复数E&S模型的磁场有限元分析公式,并以环形铁心模型为例,将复数E&S模型与传统E&S模型的计算结果进行了对比研究,指出复数E&S模型与有限元结合时既能够节省计算时间又能够保证材料特性模拟的准确性,是一种更适用于工程应用的矢量磁特性模型。 | 刘洋 张艳丽 谢德馨 白保东 KOH Chang Seop | 2012 | 中国电机工程学报2012，32，3： | 15 |
| 12 | Postoperative bleeding in patients on antithrombotic therapy after gastric endoscopic submucosal dissection显示文摘AIM To investigated the relationship between postoperative bleeding following gastric endoscopic submucosal dissection(ESD) and individual antithrombotic agents.METHODS A total of 2488 gastric neoplasms in 2148 consecutive patients treated between May 2001 and June 2016 were studied. The antithrombotic agents were categorized into antiplatelet agents, anticoagulants, and other antithrombotic agents, and we included combination therapies [e.g., dual antiplatelet therapy(DAPT)]. The risk factors associated with post-ESD bleeding, namely, antithrombotic agents overall, individual antithrombotic agents, withdrawal or continuation of antithrombotic agents, and bleeding onset period(during the first six days or thereafter), were analyzed using univariate and multivariate analyses.RESULTS The en bloc resection and complete curative resection rates were 99.2% and 91.9%, respectively. Postoperative bleeding occurred in 5.1% cases. Bleeding occurred in 10.3% of the patients administered antithrombotic agents. Being male(P = 0.007), specimen size(P < 0.001), and antithrombotic agent used(P < 0.001) were independent risk factors for postoperative bleeding. Heparin bridging therapy(HBT)(P = 0.002) and DAPT/multidrug combinations(P < 0.001) were independent risk factors associated with postoperative bleeding. The bleeding rate of the antithrombotic agent continuation group was significantly higher than that of the withdrawal group(P < 0.01). Bleeding within postoperative day(POD) 6 was significantly higher in warfarin(P = 0.015), and bleeding after POD 7 was significantly higher in DAPT/multidrug combinations(P = 0.007). No thromboembolic events were reported.CONCLUSION We must closely monitor patients administered HBT and DAPT/multidrug combinations after gastric ESD, particularly those administered multidrug combinations after discharge. | Chiko Sato Kingo Hirasawa Ryonho Koh Ryosuke Ikeda Takehide Fukuchi Ryosuke Kobayashi Hiroaki Kaneko Makomo Makazu Shin Maeda | 2017 | World Journal of Gastroenterology2017，23，30： | 14 |
| 13 | Intrahepatic biliary cystadenoma:Is there really an almost exclusively female predominance?显示文摘Biliary cystic tumors,such as cystadenomas and cystadenocarcinomas,are rare cystic tumors of the liver,accounting for less than 5% of all intrahepatic cysts of biliary origin.Biliary cystadenomas have been known to occur predominantly in women (> 85%),and 38%-44% of biliary cystadenocarcinomas have occurred in males.We wrote this letter to comment on a brief article (World J Gasteroenterol 2011 January 21;17(3):361-365) regarding a case of intrahepatic biliary cystic neoplasm treated with surgery.The adenoma-carcinoma sequence is the possible mechanism of carcinogenesis.If the carcinogenesis of biliary cystadenocarcinoma occurs in the adenoma-carcinoma sequence,we believe that the male-to-female ratio of cystadenoma should be higher than the incidence rate that has been reported to date. | Ho Hyun Kim Young Hoe Hur Yang Seok Koh Chol Kyoon Cho Jin Woong Kim | 2011 | World Journal of Gastroenterology2011，17，25： | 12 |
| 14 | Poor performance of the modified early warning score for predicting mortality in critically ill patients presenting to an emergency department显示文摘BACKGROUND:This study was undertaken to validate the use of the modified early warning score(MEWS) as a predictor of patient mortality and intensive care unit(ICU)/ high dependency(HD)admission in an Asian population.METHODS:The MEWS was applied to a retrospective cohort of 1 024 critically ill patients presenting to a large Asian tertiary emergency department(ED) between November 2006 and December2007.Individual MEWS was calculated based on vital signs parameters on arrival at ED.Outcomes of mortality and ICU/HD admission were obtained from hospital records.The ability of the composite MEWS and its individual components to predict mortality within 30 days from ED visit was assessed.Sensitivity,specificity,positive and negative predictive values were derived and compared with values from other cohorts.A MEWS of ≥4 was chosen as the cut-off value for poor prognosis based on previous studies.RESULTS:A total of 311(30.4%) critically ill patients were presented with a MEWS ≥4.Their mean age was 61.4 years(SD 18.1) with a male to female ratio of 1.10.Of the 311 patients,53(17%)died within 30 days,64(20.6%) were admitted to ICU and 86(27.7%) were admitted to HD.The area under the receiver operating characteristic curve was 0.71 with a sensitivity of 53.0%and a specificity of 72.1%in addition to a positive predictive value(PPV) of 17.0%and a negative predictive value(NPV)of 93.4%(MEWS cut-off of ≥4) for predicting mortality.CONCLUSION:The composite MEWS did not perform well in predicting poor patient outcomes for critically ill patients presenting to an ED. | Le Onn Ho Huihua Li Nur Shahidah Zhi Xiong Koh Papia Sultana Marcus Eng Hock Ong | 2013 | World Journal of Emergency Medicine2013，4，4： | 12 |
| 15 | 从分子水平探讨中国东北狍的分类地位显示文摘国内外对中国狍的分类地位意见不一。本文测定了来自中国东北完达山、小兴安岭、大兴安岭、三江和吉林向海等 5个地区的 15只野生狍的线粒体DNACytb基因 (4 15bp)和来自完达山、三江和吉林向海等 3个地区的 6只野生狍的线粒体控制区部分序列 (76 4bp) ,分析了中国东北狍与西伯利亚狍、欧洲狍的系统进化关系 ,得出中国东北狍与欧洲狍之间mtDNACytb和mtDNA控制区序列差异平均值分别为 4 12 %和 4 89% ,达到了鹿类动物的种间差异水平 ;而与西伯利亚狍的mtDNACytb和mtDNA控制区序列差异平均值仅为 1 6 1%和 2 4 4 % ,只达到亚种水平。结合形态学的差异 ,本文认为中国东北的狍与欧洲狍为两个独立的物种 ,与西伯利亚狍为同种。并提出中国东北狍与欧洲狍的分歧时间约在 2 0 0万年前 ,与西伯利亚狍的分歧时间约在 | 张明海 肖朝庭 Koh Hungsun | 2005 | 兽类学报2005，25，1： | 12 |
| 16 | Long-term outcome in patients with obscure gastrointestinal bleeding after negative capsule endoscopy显示文摘AIM:To investigate long-term outcome in obscure gastrointestinal bleeding(OGIB) after negative capsule endoscopy(CE) and identify risk factors for rebleeding.METHODS:A total of 113 consecutive patients underwent CE for OGIB from May 2003 to June 2010 at Seoul National University Hospital.Ninety-five patients(84.1%) with a subsequent follow-up after CE of at least 6 mo were enrolled in this study.Follow-up data were obtained from the patients' medical records.The CE images were reviewed by two board-certified gastroenterologists and consensus diagnosis was used in all cases.The primary outcome measure was the detection of rebleeding after CE,and factors associated with rebleeding were evaluated using multivariate analysis.RESULTS:Of the 95 enrolled patients(median age 61 years,range 17-85 years),62 patients(65.3%) were male.The median duration of follow-up was 23.7 mo(range 6.0-89.4 mo).Seventy-three patients(76.8%) underwent CE for obscure-overt bleeding.Complete examination of the small bowel was achieved in 77 cases(81.1%).Significant lesions were found in 38 patients(40.0%).The overall rebleeding rate was 28.4%.The rebleeding rate was higher in patients with positive CE(36.8%) than in those with negative CE(22.8%).However,there was no significant difference in cumulative rebleeding rates between the two groups(log rank test;P = 0.205).Anticoagulation after CE examination was an independent risk factor for rebleeding(hazard ratio,5.019;95%CI,1.560-16.145;P = 0.007),regardless of CE results.CONCLUSION:Patients with OGIB and negative CE have a potential risk of rebleeding.Therefore,close observation is required and alternative modalities should be considered in suspicious cases. | Seong-Joon Koh Jong Pil Im Ji Won Kim Byeong Gwan Kim Kook Lae Lee Sang Gyun Kim Joo Sung Kim Hyun Chae Jung | 2013 | World Journal of Gastroenterology2013，19，10： | 12 |
| 17 | 亚洲近视管理共识显示文摘指南的目标本指南是从国际近视研究所(IMI)白皮书中提取出来的有关近视管理方面的建议[1,2]。本指南所提供的内容都是根据现有最新数据(截至2022年3月)而来,其治疗可行性和执业范围因地区而异,应根据实际情况做调整。眼保健专家组通过对现有最优科学数据进行分析诠释,从而形成了本指南。在工作中,近视管理从业者应该将患者需求放在首位,全面考虑患者具体情况后再提出合适的处理意见。 | Monica Jong Serge Resnikoff Kah Ooi Tan 吕帆 Kah Meng Chung 胡楚南 Ian Morgan Oliver Kam Tong Woo 蓝卫忠 齐备 瞿佳 杨智宽 樊志诚 吴佩昌 Ian Flitcroft Murphy Hian Kee Chan Thok Chuan Tan Charlie Ho David Chai Wong Chong Liang Hwee Koh Olivia Qian Ru Cheng | 2022 | 中华眼视光学与视觉科学杂志2022，24，3： | 11 |
| 18 | 耦合改进型矢量磁滞模型的变压器磁场分析及实验研究显示文摘为了准确分析变压器、电机等电工设备的磁性能,在基于传统Chua-type模型的基础上,提出了一种直接描述电工钢片磁场强度H与磁通密度B数学关系的改进型矢量磁滞模型,其中模型参数由单片电工钢片磁特性测量系统获得;推导了不同轧制方向磁滞模型的数学表达式,讨论了耦合该磁滞模型的时步有限元计算的收敛性,并通过对单相变压器铁心模型磁场的实验测试,验证了耦合磁滞模型有限元分析的有效性。 | 张艳丽 刘洋 谢德馨 KOH Chang-Seop | 2010 | 中国电机工程学报2010，30，21： | 10 |
| 19 | Systematic review of the outcomes of surgical resection for intermediate and advanced Barcelona Clinic Liver Cancer stage hepatocellular carcinoma:A critical appraisal of the evidence显示文摘AIM To perform a systematic review to determine the survival outcomes after curative resection of intermediate and advanced hepatocellular carcinomas(HCC).METHODS A systematic review of the published literature was performed using the PubM ed database from 1 st January 1999 to 31 st Dec 2014 to identify studies that reported outcomes of liver resection as the primary curative treatment for Barcelona Clinic Liver Cancer(BCLC) stage B or C HCC. The primary end point was to determine the overall survival(OS) and disease free survival(DFS) of liver resection of HCC in BCLC stage B or C in patients with adequate liver reserve(i.e., Child's A or B status). The secondary end points were to assess the morbidity and mortality of liver resection in large HCC(defined as lesions larger than 10 cm in diameter) and to compare the OS and DFS after surgical resection of solitary vs multifocal HCC.RESULTS We identified 74 articles which met the inclusion criteria and were analyzed in this systematic review. Analysis of the resection outcomes of the included studies were grouped according to(1) BCLC stage B or C HCC,(2) Size of HCC and(3) multifocal tumors. The median 5-year OS of BCLC stage B was 38.7%(range 10.0-57.0); while the median 5-year OS of BCLC stage C was 20.0%(range 0.0-42.0). The collective median 5-year OS of both stages was 27.9%(0.0-57.0). In examining the morbidity and mortality following liver resection in large HCC, the pooled RR for morbidity [RR(95%CI) = 1.00(0.76-1.31)] and mortality [RR(95%CI) = 1.15(0.73-1.80)] were not significant. Within the spectrum of BCLC B and C lesions, tumors greater than 10 cm were reported to have median 5-year OS of 33.0% and multifocal lesions 54.0%.CONCLUSION Indication for surgical resection should be extended to BCLC stage B lesions in selected patients. Further studies are needed to stratify stage C lesions for resection. | Ye Xin Koh Hwee Leong Tan Weng Kit Lye Juinn Huar Kam Adrian Kah Heng Chiow Siong San Tan Su Pin Choo Alexander Yaw Fui Chung Brian Kim Poh Goh | 2018 | World Journal of Hepatology2018，10，6： | 10 |
| 20 | 智慧城市评价体系研究显示文摘智慧城市建设是全球城市建设的新趋势,中国于2010年开始了智慧城市的建设。但相对于实践建设的如火如荼,学术界对于智慧城市的理论研究却明显滞后。本研究对智慧城市进行了理论探讨,对推动智慧城市建设具有一定的意义。 | Dan Koh | 2014 | 城市建筑2014，11，2： | 8 |
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