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1Immunohisto chemical Study on the Effects of Pyrethroids on Gluta-mate and γ-Aminobutyric Acid in Rat Central Nervous System显示文摘Objective\ In order to study the effects of pyrethroids on glutamate (Glu) and gamma aminobutyric acid (GABA) in rat central nervous system. Methods\ Male SD rats were treated with permethrin (7 mg/kg, i.p) or cypermethrin (70 mg/kg, i.p) once a day for 3 days. Glu and GABA immunoreactive cells and transmitters in CNS were studied by immunohistochemical method. Results\ The total number, percentage of positive area and integral optical density of glutamate immunoreactive cell in cerebral cortex, hippocampus decreased significantly in permethrin or cypermethrin, while GABA was enhanced. Cypermethrin is more tent than permethrin on either Glu or GABA. Conclusion\ Disturbance of Glu and GABA is likely to play a role in the development of pyrethroids excitatory neurotoxicity.Wu Jianping, Lu Chun\+1, Wang Ying, et al. Wu Jianping, Lu Chun\+1, Wang Ying, et al. Institute of Toxicology, Nanjing Medical University, Nanjing\ 210029 Acta Universitatis Medicinalis Nanjing,19(6):450 1999The Journal of Biomedical Research1999,23,2:68
2Nerve Growth Factor Prevents the Apoptosis-associated Increase in Acetylcholinesterase Activity after Hydrogen Peroxide Treatment by Activating Akt显示文摘Acetylcholinesterase (疼痛) 被认为玩结果显示出的重要角色 duringapoptosis.Our 那 H_2O_2 导致了疼痛活动,功能的标记 inapoptosis,象 neuronal 一样 PC 12 房间的增加。谷胱甘肽,涉及细胞的氧化还原作用动态平衡,禁止了疼痛活动的增加,建议在这个过程的那个反应的氧种类(ROS ) 千盐湖钥匙角色。进一步的调查证明疼痛的举起在 Akt,从进 cytosol 的线粒体的细胞色素 c 的版本,和 caspase 家庭成员的激活的降级以后被观察。神经生长因素(NGF ) 什么时候是在场的,与 Akt 水平,疼痛的举起,细胞色素 c 散开,以及 apoptosis 的维护,显著地在对待 H_2O_2 的 PC12 细胞被稀释。然而, wortmannin, PI3K/Aktpathway 的一个禁止者,加速了 apoptosis 并且增加了疼痛活动。过去表示 ofconstitutively 激活 Akt,它是 NGF receptorTrkA,推迟的 mitochondrial 倒塌和疼痛活动的禁止的举起的一个下游的发信号元素。因此, NGF preventedapoptosis 和由激活 Akt 小径并且稳定线粒体的功能的疼痛活动的举起。Hua JIANG~(1,3) Jingya ZHANG~(1,3) Hui ZHU~(1,3) Hong LI~2 and Xuejun ZHANG~1 ~1Laboratory of Molecular Cell Biology,Institute of Biochemistry and Cell Biology,Shangha Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China ~2DEFEMA,Faculté de Medecine et de Pharmacie,University of Rouen,Rouen 76821,France ~3Graduate school of the Chinese Academy of Sciences,Beijing 100080,China 2007Acta Biochimica et Biophysica Sinica2007,39,1:9
3Schur convexity for a class of symmetric functions显示文摘The Schur convexity and concavity of a class of symmetric functions are discussed, and an open problem proposed by Guan in 'Some properties of a class of symmetric functions' is answered. As consequences, some inequalities are established by use of the theory of majorization.CHU YuMing 1, XIA WeiFeng 1 & ZHAO TieHong 2 1 Department of Mathematics, Huzhou Teachers College, Huzhou 313000, China 2 Institut de Mathmatiques, Universit Pierre et Marie Curie, Paris F-75252, France 2010Science China Mathematics2010,53,2:6
4广西地层之一──《广西的泥盆系》显示文摘广西地层之一──《广西的泥盆系》《广西的泥盆系》是根据地质矿产部“七五”科研项目《广西泥盆纪断代总结》的成果编纂而成,由中国地质大学出版社于1992年出版发行。参加该项目的研究人员有广西壮族自治区地质矿产局的钟铿、吴诒、殷保安、梁演林、姚肇贵、彭金兰...Zhong Keng et al.(China Geosciences University Publishing House,1992)(zhong Keng,Bareau of Oeolwg&Mineral Resources auangzi zhuang AutDnomous ffegfon,1 Jianzheng Road,Nanninq,ffeangxi,530023)ISBN 7-5625-0661-2P. 237 1994广西科学1994,1,1:2
5An Analysis of 100 Cases of Obstructive Jaundice by CT Scans显示文摘AnAnalysisof100CasesofObstructiveJaundicebyCTScans¥HuangQinjuan,etal.ACTAACADEMIAEMEDICINAENANJING,1994,14(1):62-64Abstract:T...Huang Qinjuan,et al. ACTA ACADEMIAE MEDICINAE NANJING,1994,14(1):62-64 1994The Journal of Biomedical Research1994,18,1:2
62010年美国风湿病学会关于类固醇性骨质疏松症的预防和治疗推荐显示文摘糖皮质激素(glucocorticoids,GCs)因能有效控制多种炎性反应而被广泛应用,但其与一些疾病的发生率和死亡率显著相关。骨质疏松症及相关性骨折是其合并症之一,可伴有剧痛并致残。JENNIFER M. GROSSMAN REBECCA GORDON VEENA K. RANGANATH 1 CHAD DEAL( et al) 徐蕙(摘译) 蒋颖(审校) 2011中华骨质疏松和骨矿盐疾病杂志2011,4,3:2
7Unusual small intestinal ob- struction in adolescent girls:the abdominal cocoon显示文摘FOO KT NG KC RAUFF A et a 1 1978Br J Surg1978,65,6:1
82显示文摘EVANS H K WYLIE A A MURPHY S K et akThe neuronatin gene resides in a micro-imprinted domain on human chromosome 20ql 1 2001Genomics2001,77,12:1
9Morbidity of en bloc rescetiens in the spine显示文摘Bofiani $ Bandiera 8 Donthineni P et a 1 2010Eur Spine J2010,19,:1
10Incremental value ofT2-we i gh t ed and d i f f us i on-weighted MRI for predictionof biochemical recurrenceafter radical prostatectomy inclinically localized prostatecancer 显示文摘N i sh ida K Yuen S Kamo i K et a 1 2011Acta Radiol2011,52,2:1
11Reproducibility of SELDI Speca Across Time and Laboratories显示文摘Diao L Clarke CH Coombes KR et o!1 2011Cancer In- form2011,10,3:1
12GRP78 expression inhibits insulin and ER stress-induced SREBP-lc activation and reduces hepatic steatosis in mice显示文摘Kammoun HL Chabanon H Hainault 1 et'al 2009J Clin Invest2009,119,:1
13Prostatecancer: role of pretreatmentM R in predicting outcomeafter externalbeam radiationtherapy-initial experience显示文摘McKennaDA Coak1ey FV Westphalen AC et a 1 2008Radiology2008,247,3:1
14Retinoic acids are potent inhibitors of spontaneous human eosinophil apoptosis显示文摘Ueki S Mahemuti G Oyamada H et a 1 2008J Imnm- nol2008,181,11:1
15Pathophysiology of acute pancre-atitis 显示文摘Bhatia M Wong FL Cao Y et a 1 2005Pancreatology2005,5,23:1
16显示文摘Ichimura T Bonventre JV Bailly V et aL Kidney injury molecule - ( KIM - 1 ) a putative epithelial eel1 adhesion molecule containing novel immunoglobulin domain is up- regulated in renal coils after it jury 1998J Biol Chem1998,273,7:1
17Relevance of microbial coculture fermentations in biotechnology显示文摘Bader J Mast -Gerlach E Popovic MK et (1/ 2010Journal of Applied Microbiology2010,109,2:1
18Pharmacologicalprofiles of opioid ligands at Kappa opioid receptors显示文摘Parha M Ezzat H Timothy MD et a 1 2006BMCPharmacol2006,95,6:1
199 Ga, continental margin, back-arc, felsic caldera province with diverse Zn-Pb-Ag-(Cu-Au) sulfide and Fe oxide deposits, Bergslagen re- gion, Sweden显示文摘Allen R L Lundstrom I PApa M et aL Facies analysis of a 1 1996Economic Geology1996,91,6:1
20Rivaroxaban attenuates leukocyte adhesion in the microvaseulature and thrombus formation in an experimental mouse model of type 2 diabetes mellitus 显示文摘Iba T Aihara K Yamada A et a 1 2014Thromb Res2014,133,2:1
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