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| 1 | Nutritional and medicinal characteristics of Chinese giant salamander (Andrias davidianus) for applications in healthcare industry by artificial cultivation: A review显示文摘Andrias davidianus,i.e.Chinese giant salamander(CGS),is one of the largest and oldest amphibians existing in the world and is also one of the valuable biological resources of China.Wild CGS has been threatened with extinction in the past decades due to over capturing,deterioration of natural environment,the slow breeding and growth of the wild species in nature.However,in the past twenty years,with the breakthrough and progress of artificial breeding technology by artificial insemination,the number of artificially cultivated CGS has increased rapidly.Artificially cultivated CGS can either be released to the CGS living environment to increase the population in nature or legally applied in food and medicinal industry as a feedstock due to the unique nutritional and medicinal values of CGS as recorded historically.In this review,the nutritional components,bioactive components and medicinal activities of the artificially cultivated CGS will be summarized.The mucus,skin,meat and bone of CGS contain many different bioactive substances thereby having various medicinal activities including anti-aging,anti-fatigue,anti-tumor,therapy of burn and anti-infection and other physiological functions.This paper will further discuss the potential applications of the artificially cultivated CGS in healthcare industry and prospects of future technological development. | Dong He Wenming Zhu Wen Zenga Jun Lin Yang Ji Yi Wang Chong Zhang Yuan Lu Daoquan Zhao Nan Su Xin-Hui Xing | 2018 | Food Science and Human Wellness2018，7，1： | 28 |
| 2 | Classification, Expression Pattern, and E3 Ligase Activity Assay of Rice U-Box-Containing Proteins显示文摘Ubiquitin ligases 玩在由为修正选择无数适当候选人蛋白质决定 ubiquitination 系统的特性的一个中央角色。U 盒子是一最近识别了,显示出更大的存在在的活动相关的蛋白质领域比在另外的有机体种的 ubiquitin ligase。在这研究,我们用一组整个染色体分析算法从米饭染色体识别了 77 通常认为的 U 盒子蛋白质。大多数 U 盒子蛋白质基因被表示,支持旁边他们的相应表示顺序标签(EST ) 的鉴定,全身的 cDNAs,或定序的大规模平行的签名(MPSS ) 标注。用一样的算法,我们从 Arabidopsis 染色体识别了 61 U 盒子蛋白质。米饭和 Arabidopsis U 盒子蛋白质基于他们的领域作文被分类进九个主要的班。在米饭和 Arabidopsis U 盒子蛋白质之间的比较显示米饭和 Arabidopsis U 盒子蛋白质的多数有一样的领域组织。推断的发展史建立了在米饭和 Arabidopsis U-box/ARM 蛋白质之间的相同。用米饭原物系统的房间死亡试金建议那一米饭 U 盒子基因, OsPUB51,可能充当房间死亡发信号的一个否定管理者。另外,选择 U 盒子蛋白质被发现是功能的 E3 ubiquitin ligases。在此,在 genomic,水平将机能上地帮助的米饭 U 盒子蛋白质的鉴定和分析以后描绘 E3 ubiquitin ligase 的这个班。 | Li-Rong Zenga Chan Ho Park R.C. Venu Julian Gough Guo-Liang Wang | 2008 | Molecular Plant2008，1，5： | 15 |
| 3 | Analysis of species-dependent hydrolysis and protein binding of esmolol enantiomers显示文摘The stereoselective hydrolysis of esmolol in whole blood and in its separated components from rat,rabbit and human was investigated.Blood esterase activities were variable in different species in the order of rat>rabbit>human.Rat plasma showed the high esterase activity and had no stereoselectivity to enantiomers.Rabbit red blood cell(RBC) membrane,RBC cytosol and plasma all hydrolyzed esmolol but with different esterase activity,whereas the hydrolysis in RBC membrane and cytosol showed significant stereoselectivity towards R-(+)-esmolol.Esterase in RBC cytosol from human blood mainly contributed to the esmolol hydrolysis,which was demonstrated with no stereoselctivity.Esterase in human plasma showed a low activity,but a remarkable stereoselectivity with R-(+)-esmolol.In addition,the protein concentration affected the hydrolysis behavior of esmolol in RBC suspension.Protein binding of esmolol enantiomers in human plasma,human serum albumin(HSA) and α_1-acid glycoprotein(AGP) revealed that there was a significant difference in bound fractions between two enantiomers,especially for AGP.Our results indicated that the stereoselective protein binding might play a role in the different hydrolysis rates of esmolol enantiomers in human plasma. | Yi-Hong Tanga,b,1,Jun-Yan Wanga,1,Hai-Hong Hua,Tong-Wei Yaoa,Su Zenga,n aDepartment of Pharmaceutical Analysis and Drug Metabolism,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,Zhejiang 310058,People’s Republic of China bShanghai Institute of Technology,Shanghai 201418,People’s Republic of China | 2012 | Journal of Pharmaceutical Analysis2012，2，3： | 3 |
| 4 | Simple and sensitive determination of sparfloxacin in pharmaceuticals and biological samples by immunoassay显示文摘Plasma quinolone concentrations are not routinely measured in clinical practice.However,in order to optimize quinolone treatment,monitoring of plasma concentrations could sometimes be useful particularly in critically ill patients.In this study,anti-sparfloxacin antibody was obtained by immunizing rabbits with sparfloxacin conjugated with bovine serum albumin using isobutyl chloroformate method.After the assay procedure was optimized,the standard curve of sparfloxacin was established.The practical measuring range of the competitive ELISA extended from 5 ng/mL to 2 mg/mL.The recovery rates and coefficients of variation for rat plasma,urine and tissues were 87.7-106.2% and 4.8-15.3%,respectively.To demonstrate the potential of the ELISA,a preliminary pharmacokinetics and tissue distribution study of sparfloxacin in rats and quantitative analysis of sparfloxacin in several pharmaceuticals were performed and compared with high-performance liquid chromatography(HPLC).The experimental data indicated that the proposed method would be a valuable tool in therapeutic drug monitoring(TDM) for sparfloxacin. | Hua-Jin Zenga,Ran Yangb,Bing Liub,Li-Fang Leib,Jian-Jun Lib,Ling-Bo Qub,c,n aSchool of Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China bDepartment of Chemistry,Zhengzhou University,Zhengzhou 450001,China cSchool of Chemistry & Chemical Engineering,Henan University of Technology,Zhengzhou 450001,China | 2012 | Journal of Pharmaceutical Analysis2012，2，3： | 2 |
| 5 | Effects of process variables on interfacial quality of laser cladding on aeroengine blade material GH4133 materials processing technology 显示文摘 | Zheng Xionga Guang-xia Chena Xiao-yan Zenga | 2009 | Journal of Materials Processing Technology2009，209，： | 1 |
| 6 | Degradation of phenol by ozone in the presence of Fenton reagent in a rotating packed bed显示文摘 | ZENGA Z ZOUB H LIC X | 2013 | Chemical Engineering Journal2013，229，： | 1 |
| 7 | Solid lipid nanoparticles: could they help to improve the efficacy of pharmaeologle treatments for brain tumors? 显示文摘 | Brioschi A Zenga F Zara GP | 2007 | Neurol Res2007，29，3： | 1 |
| 8 | Fibrinogen-bearing protein genes in the snail Biomphalaria glabrata : characterization of two novel genes and expression studies during ontogenesis and trematode infection 显示文摘 | Zhanga SM Niana H Zenga Y | 2008 | Dev Comp Immuno12008，32，3： | 1 |
| 9 | A semi-torsional spring analogy model for updating unstructured meshes in 3D moving domains 显示文摘 | Zenga D Ethier C | 2005 | Finite Elements in Analysis and Design2005，41，1： | 1 |
| 10 | Design and Characterization of GRC-1 : a Soil for Lunar Terra- mechanics Testing in Earth-ambient Conditions显示文摘 | Oraveca H A Zenga X Asnani V M | 2010 | Journal of Terramechanics2010，47，6： | 1 |
| 11 | A semi-torsional spring analogy model for updating unstructured meshes in 3D moving domains显示文摘 | Zenga D Ethier C R | 2005 | Finite Elements in Analysis and Design2005，41，1112： | 1 |
| 12 | Posttraumatic epilepsy with special emphasis on prophylaxis and prevention显示文摘 | Pagni CA Zenga F | 2005 | Acta Neuro-chir Suppl2005，93，： | 1 |
| 13 | Enhanced mechanical properties in an A1-Cu-Mg-Ag alloy by duplex aging 显示文摘 | YAO Li ZHIYI Liua SONG Baia XUANWEI Zhoua HENG Wanga SUMIN Zenga | 2011 | Materials Science and Engineering A2011，528，28： | 1 |
| 14 | Posttraumatic epilepsy with special emphasis on prophylaxis and prevention显示文摘 | Pagni CA Zenga F | 2005 | Acta Neurochir Suppl2005，93，： | 1 |
| 15 | High porosity and large pore size shape memory alloys fabricated by using poreforming agent(NH4 HCO3)and capsule-free hot isostatic pressing显示文摘 | ZHANG Y P YUANA B ZENGA M Q | 2007 | Journal of Materials Processing Technology2007，，： | 1 |
| 16 | Experimental study of heat transfer enhancement in narrow rectangular channel with longitudinal vortex generators显示文摘 | Wang Q Chena Q Wang L Zenga M | 2007 | Nuclear Engineering and Design2007，237，68： | 1 |
| 17 | Solid lipid nanoparticles:could they help to improve the efficacy of pharmacologic treatments for brain tumors?显示文摘 | BRIOSCHI A ZENGA F ZARA G P | 2007 | Neurol Res2007，29，3： | 1 |
| 18 | Data-driven predictive control for blast furnace iron making process显示文摘 | Zenga Jiu-sun Gaob Chuan-hou Sua Hong-ye | 2010 | Computers and Chemical Engineering2010，34，2： | 1 |
| 19 | Application of a fuzzy based de-cision making methodology to construction project risk as-sessment显示文摘 | Zenga J Ana M Smith N J | 2007 | International Journal of Project Management EI2007，25，6： | 1 |
| 20 | Controlled synthesis of α-Fe2O3 nanostructures and their size-dependent electrochemical properties for lithiumion batteries 显示文摘 | Yanna NuLl Rong Zenga Peng Zhanga | 2008 | Journal of Power Sources2008，184，： | 1 |
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