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| 1 | Blood platelet and monocyte activations and relation to stages of liver cirrhosis显示文摘AIM: Blood platelets (plt) and monocytes are the cells that play a crucial role in the pathogenesis of liver damage and liver cirrhosis (LC). In this paper, the analysis of mutual relationship between platelets and monocytes activation in LC was conducted.METHODS: Immunofluorescent flow cytometry was usedto measure the percentage of activated platelet populations(CD62P, CD63), the percentage of plt-monocyte aggregates (pma) (CD41/CD45), and activated monocytes (CD11b, CD14, CD16) in the blood of 20 volunteers and 40 patientswith LC. Platelet activation markers: sP-selectin, platelet factor 4 (PF4), beta-thromboglobulin (βTG) and monocyte chemotactic peptide-1 (MCP-1) were measured and compared in different stages of LC.RESULTS: Platelet activation with the increase in bothβTG serum concentration and elevation of plt population(CD62P and CD63 as well as MIF CD62P and CD63) is elevated as LC develops and thrombocytopenia rises. There is a positive correlation between medial intensityof fluorescence (MIF) CD62P and MIF CD63 in LC. We did not show any relationship between monocyte activation and pma level. SP-selectin concentration correlates positively with plt count and pma, and negatively with stage of plt activation and MIF CD62P and MIF CD63. There was no correlation between MCP-1 concentration andpit, monocyte activation as well as pma level in LC. CD16 monocytes and MIF CD16 populations are significantlyhigher in the end stage of LC. A positive correlation occurs between the value of CD11b monocyte population andMIF CD14 and MIF CD16 on monocytes in LC.CONCLUSION: Platelet and monocyte activation plays an important role in LC. Platelet activation stage does not influence monocyte activation and production of plt aggregates with monocytes in LC. With LC development, thrombocytopenia may be the result of plt consumption in platelet-monocyte aggregates. | Anatol Panasiuk Janusz Zak Edwina Kasprzycka Katarzyna Janicka Danuta Prokopowicz | 2005 | World Journal of Gastroenterology2005，11，18： | 11 |
| 2 | WS2 nanoflakes from nanotubes for electrocatalysis显示文摘为切开的水的下一代的催化剂向可更新的氢经济是关键的。MoS2 和 WS2 在边地点与高催化的活动代表地球丰富的、高贵金属阴极选择。在他们的开发的一挑战是这些材料到 nanostructure 以便通过另外的边地点的创造完成增加的性能。在这个工作,我们表明一条简单线路用 sonochemical 脱落形成 nanostructured-WS2 在 WS2 nanotubes 打破夹层和 intralayer 契约。产生很少层 nanoflakes 是与边地点的高密度宽的 100 nm。WS2 nanoflakes 为氢进化反应作为阴极被利用(她的) 并且展览上级性能到 WS2 nanotubes 和体积粒子与一个更低的发作潜力,更浅的 Tafel 斜坡和增加的当前的密度。未来工作可以采用进一步改进 electrocatalytic 活动的极端小的 nanoflakes,掺杂物原子,或 graphene 混血儿。 | Charina L. Choi Ju Feng Yanguang Li Justin Wu Alia Zak Reshef Tenne Hongjie Dai | 2013 | Nano Research2013，6，12： | 11 |
| 3 | Combination therapy using evening primrose oil and electrical stimulation to improve nerve function following a crush injury of sciatic nerve in male rats显示文摘Peripheral nerve injuries with a poor prognosis are common.Evening primrose oil(EPO) has beneficial biological effects and immunomodulatory properties.Since electrical activity plays a major role in neural regeneration,the present study investigated the effects of electrical stimulation(ES),combined with evening primrose oil(EPO),on sciatic nerve function after a crush injury in rats.In anesthetized rats,the sciatic nerve was crushed using small haemostatic forceps followed by ES and/or EPO treatment for 4 weeks.Functional recovery of the sciatic nerve was assessed using the sciatic functional index.Histopathological changes of gastrocnemius muscle atrophy were investigated by light microscopy.Electrophysiological changes were assessed by the nerve conduction velocity of sciatic nerves.Immunohistochemistry was used to determine the remyelination of the sciatic nerve following the interventions.EPO + ES,EPO,and ES obviously improved sciatic nerve function assessed by the sciatic functional index and nerve conduction velocity of the sciatic nerve at 28 days after operation.Expression of the peripheral nerve remyelination marker,protein zero(P0),was increased in the treatment groups at 28 days after operation.Muscle atrophy severity was decreased significantly while the nerve conduction velocity was increased significantly in rats with sciatic nerve injury in the injury + EPO + ES group than in the EPO or ES group.Totally speaking,the combined use of EPO and ES may produce an improving effect on the function of sciatic nerves injured by a crush.The increased expression of P0 may have contributed to improving the functional effects of combination therapy with EPO and ES as well as the electrophysiological and histopathological features of the injured peripheral nerve. | Omid Badri Parviz Shahabi Jalal Abdolalizadeh Mohammad Reza Alipour Hadi Veladi Mehdi Farhoudi Mohsen Sharif Zak | 2017 | Neural Regeneration Research2017，12，3： | 7 |
| 4 | WC-Co硬质合金表面渗碳强化工艺研究与应用显示文摘研究开发了一种WC-Co硬质合金的表面渗碳强化处理工艺,对WC-Co硬质合金经过表面渗碳处理后的性能进行了对比评价,结果显示,WC-Co硬质合金齿经过表面渗碳处理后,可获得1 mm以上厚度的硬化层。按开发的表面渗碳工艺处理后的硬质合金齿,耐磨性有明显改善,抗压缩疲劳能力和抗冲击能力均有显著提高。经表面渗碳强化处理的硬质合金齿在牙轮钻头上进行了钻井现场试验,显示了更好的进尺能力和更高的钻速。 | 张烈华 Zhigang Zak Fang 许林 | 2016 | 金属热处理2016，41，2： | 6 |
| 5 | Phagocytic and oxidative burst activity of neutrophils in the end stage of liver cirrhosis显示文摘AIM: To evaluate the phagocytic activity and neutrophil oxidative burst in liver cirrhosis.METHODS: In 45 patients with advanced postalcoholic liver cirrhosis (aged 45±14 years) and in 25 healthy volunteers (aged 38±5 years), the percentage of phagocytizing cells after in vitro incubation with E. coli (Phagotest Kit), phagocytic activity (mean intensity of fluorescence, MIF) and the percentage of neutrophil oxidative burst (Bursttest Kit), and the level of free oxygen radical production (MIF of Rodamine 123)were analyzed by flow cytometry. The levels of soluble sICAM-1, sVCAM-1, sP-selectin, sE-selectin, sL-selectin,and TNF-α were determined in blood serum.RESULTS: The percentage of E. coli phagocytizing neutrophils in liver cirrhosis patients was comparable to that in healthy subjects. MIF of neutrophil - ingested E. coli was higher in patients with liver cirrhosis. The oxidative burst in E. coli phagocytizing neutrophils generated less amount of active oxygen compounds in liver cirrhosis patients (MIF of R123:24.7±7.1 and 29.7±6.6 in healthy,P<0.01). Phorbol myristate acetate (PMA) - stimulated neutrophilsproduced less reactive oxidants in liver cirrhosis patients than in healthy subjects (MIF of R123: 42.7±14.6 vs 50.2±13.3, P<0.01). A negative correlation was observed between oxidative burst MIF of PMA-stimulated neutrophils and ALT and AST levels (r -0.35, P<0.05;r-0.4, P<0.03). sVCAM-1, sICAM-1, sE-selectin concentrations correlated negatively with the oxygen free radical production (MIF of R123) in neutrophils after PMA stimulation in liver cirrhosis patients (r-0.45, P<0.05;r-0.41, P<0.05; r-0.39, P<0.05, respectively).CONCLUSION: Neutrophil metabolic activity diminishes together with the intensification of liver failure. The metabolic potential of phagocytizing neutrophils is significantly lower in liver cirrhosis patients, which can be one of the causes of immune mechanism damage. The evaluation of oxygen metabolism of E. coli-stimulated neutrophils reveals that the amount of released oxygen metabolites is smaller in liver cirrhosis patients than in healthy subjects. | Anatol Panasiuk Jolanta Wysocka Elzbieta Maciorkowska Bozena Panasiuk Danuta Prokopowicz Janusz Zak Karol Radomski | 2005 | World Journal of Gastroenterology2005，11，48： | 4 |
| 6 | 应用MRI形态学和T2图成像生化区域带评估并比较髌骨与股骨内侧髁关节软骨修复组织显示文摘本研究的目的是利用先进的MR技术评价并比较自体软骨细胞移植(MACT)术后髌骨与股骨内侧髁软骨的修复情况。34例MACT治疗后的病人行膝关节3TMRI检查,其中髌软骨17例,股骨内侧髁软骨17例,且年龄和术后间隔时间相匹配。形态学评估采用三维真实稳态自由进动序列对关节软骨修复组织进行MRI评分(MOCART)。生物化学评估采用多回波自旋回波方法行R图成像,并重点分析关节软骨区域带结构。应用方差分析进行统计学评估。 | G.H. Welsch T.C. Mamisch S. Quirbach L. Zak S. Marlovits S. Trattnig 刘艳杰(译) 李威(校) | 2009 | 国际医学放射学杂志2009，32，4： | 4 |
| 7 | 基质诱导自体软骨细胞移植术临床及放射学远期结果——术后至少10年前瞻性随访显示文摘关节软骨损伤后愈合潜能有限,治疗一直具有挑战性。有关基质诱导自体软骨细胞移植(matrixassociated autologous chondrocyte transplantation,MACT)技术,既往有报道显示其对中度至重度有症状关节软骨缺损患者的治疗安全有效,临床和放射学结果良好,尤其是在术后5年内疼痛、功能以及活动水平等方面均有明显改善。影像学结果亦表明,MACT治疗后患者组织修复好,与附着物结合紧密。 | Aldrian S Zak L Wondrasch B 沈洪园 尹庆水 | 2014 | 中国骨科临床与基础研究杂志2014，6，6： | 4 |
| 8 | Computer analysis of reinforced concrete section under biaxial bending and longitudinal loading显示文摘 | ZAK M L | 1993 | ACI Structural Journal1993，90，2： | 2 |
| 9 | Preparation, characterization, and antibacterial activity of γ-irradiated silver nanoparticles in aqueous gelatin显示文摘Colloidal silver nanoparticles (Ag-NPs) were obtained through γ-irradiation of aqueous solutions containing AgNO 3 and gelatin as a silver source and stabilizer, respectively. The absorbed dose of γ-irradiation influences the particle diameter of the Ag-NPs, as evidenced from surface plasmon resonance (SPR) and transmission electron microscopy (TEM) images. When the γ-irradiation dose was increased (from 2 to 50 kGy), the mean particle size was decreased continuously as a result of γ-induced Ag-NPs fragmentation. The antibacterial properties of the Ag-NPs were tested against Methicillinresistant Staphylococcus aureus (MRSA) (Gram-positive) and Pseudomonas aeruginosa (P.a) (Gram-negative) bacteria. This approach reveals that the γ-irradiation-mediated method is a promising simple route for synthesizing highly stable Ag-NPs in aqueous solutions with good antibacterial properties for different applications. | Majid Darroudi Mansor B. Ahmad Mohammad Hakimi Reza Zamiri Ali Khorsand Zak Hasan Ali Hosseini Mohsen Zargar | 2013 | International Journal of Minerals,Metallurgy and Materials2013，20，4： | 2 |
| 10 | New reactor for production of tungsten disulfide hollow onion-like (inorganic fullerene-like) nanoparticles显示文摘 | Zak A Popovita-Biro R | 2000 | Solid State Sci2000，2，： | 1 |
| 11 | Synergistic effects between 561A> C and 98G > T polymorphisms of E-selectin gene and hypercholesterolemia in determining the susceptibility to coronary artery disease 显示文摘 | Zak I Sarecka B Krauze J | 2008 | Heart Vessels2008，23，4： | 1 |
| 12 | Atmospheric nitrate deposition, microbial community composition, and enzyme activity in northern hardwood forests 显示文摘 | DEFOREST J L ZAK D R PREGITZER K S | 2004 | Soil Science Society of America Journal2004，68，： | 1 |
| 13 | Enzymatic catalysis in nonaqeous solvents显示文摘 | Zaks A Klibanov AM | 1988 | Biol Chem1988，263，： | 1 |
| 14 | Output feedback variable structure controllers and state estimators for uncertain/nonlinear dynamic systems 显示文摘 | Zak H S Hui S | 1993 | IEE Proc on D1993，140，1： | 1 |
| 15 | Elevated atmospheric CO2, fine roots and the response of soil microorganisms: a review and hypothesis显示文摘 | Zak D R Pregiter U A Luscher A | 2000 | New Phytologist2000，147，： | 1 |
| 16 | Plant functional traits, ecosystem structure, and land-use history along a climatic gradient in central western Argentina显示文摘 | Diaz S Cabido M Zak M | 1999 | Journal of Vegetation Science1999，10，： | 1 |
| 17 | Grain growth during the early stage of sinterlng of nanosized WC-Co powder显示文摘 | Xu Wang Zhi gang Zak Fang Hong Yong Sohn | 2007 | International Journal of Refractory Metals & Hard Materials2007，20，4： | 1 |
| 18 | Plant species richness, elevated CO2 and atmospheric nitrogen decomposition alter soil microbial community composition and function显示文摘 | CHUNG H ZAK D R REICH P B | 2007 | Global Change Biology2007，13，： | 1 |
| 19 | Prostaglandins and the myometrium and cervix显示文摘 | Hertelendy F Zakár T | | 0，，： | 1 |
| 20 | The effect of centrifugal force on the transcription levels of collagen type I and collagenase in cultured canine gingival fibroblasts显示文摘 | Redlich M Palmon A Zaks B | 1998 | Archives of Oral Biology1998，43，4： | 1 |
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