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| 1 | A chronic ulcerative colitis model in rats显示文摘INTRODUCTIONIn recent years,there have been many reports aboutanimal model to investigate drugs for inflammatorybowel diseases (IBD).The experimental animalmodel often used is acetic acid-induced damage ofcolonic muscosa.In the present study,this animalmodel was investigated by administering variousconcentrations of TNBS. | Zheng L Gao ZQ Wang SX | 2000 | World Journal of Gastroenterology2000，6，1： | 37 |
| 2 | The value of postoperative hepatic regional chemotherapy in prevention of recurrence after radical resection of primary liver cancer显示文摘INTRODUCTIONIn China,primary liver cancer (PLC) ranks secondin cancer mortality since the 1990s.In the field ofPLC treatment,surgical resection remains the best,which includes large PLC resection,small PLCresection,re-resection of subclinical recurrence,aswell as cytoreduction and sequential resection forunresectable PLC.However,recurrence | Wu ZQ Fan J Qiu SJ Zhou J Tang ZY | 2000 | World Journal of Gastroenterology2000，6，1： | 19 |
| 3 | Hepatocellular carcinoma HepG2 cell apoptosis and caspase-8 and Bcl-2 expression induced by injectable seed extract of Coix lacryma-jobi显示文摘BACKGROUND:Many Chinese herbs,especially herbal injections,have been shown to have anti-tumor effects in recent years.However,since most reports focus on the clinical effectiveness of these herbs,their mechanisms of action are not well understood.In this study,we assessed apoptosis in the hepatocellular carcinoma (HCC) cell line HepG2 induced by an injectable extract from the seed of Coix lacryma-jobi (Semen coicis,SC),and monitored the expression of Bcl-2 and caspase-8.METHODS:Injectable SC was applied to HepG2 cells at different concentrations and the cells were collected 12,24 and 48 hours later.5-fluorouracil was used as a positive control group,and fluorescence-activated cell-sorting cytometry was used to measure the apoptosis rate of HepG2 cells and the expression of Bcl-2 and caspase-8 proteins.RESULTS:SC induced apoptosis in HepG2 cells in a concentration and time-dependent manner,and the expression of caspase-8 was elevated and prolonged.However,it did not significantly influence the expression of Bcl-2.CONCLUSION:Injectable SC may induce apoptosis in HCC cells by regulating the expression of caspase-8. | Department of General Surgery (Lu Y and Zhang BY),Department of Bio-Information (Jia ZX),Affiliated Medical College Hospital,Qingdao University,Qingdao 266003,China Shanghai Jiaotong University School of Medicine,Shanghai 200025,China (Wu WJ) Department of Medicine,Heze Medical College,Heze 274000,China (Lu ZQ) | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 17 |
| 4 | Age of the Shahewan rapakivi granite in the Qinling Orogen, China, and its constraints on the end time of the main erogenic stage of this orogen显示文摘the Qinling Mountains in central China are a joint orogenic zone between the Sino-Korean (or North China) and the Yangtze (or South China) craton blocks, the two major tectonic units of eastern Asia. On the end time of the main orogenic stage in this orogenic | Zhang, ZQ Zhang, GW Tang, SH Lu, XX | 1999 | Chinese Science Bulletin1999，44，21： | 15 |
| 5 | Anachronistic facies in the Lower Triassic of South China and their implications to the ecosystems during the recovery time显示文摘The end-Permian mass extinction not only severely distressed the Paleozoic ecosystems but also dramatically changed the sedimentary systems, resulting in a peculiar Early Triassic ecosystem and submarine environment during the recovery time following the mass extinction. The Lower Triassic is characteristic of the wide occurrence of various distinctive sediments and related sedimentary structures, such as flatpebble conglomerates, vermicular limestone, subtidal wrinkle structures, microbialite, carbonate seafloor fans, thin-bedded limestone and zebra limestone-mudstone. These sediments were common in the Precambrian to Early Ordovician marine settings, and then they occurred only in some extreme and unusual environments with the expansion of metazoan faunas. However, the Early Triassic witnessed an 'anachronistic' reappearance of some distinctive sedimentary records in normal shallow marine settings. The study of these anachronistic facies should be of great importance for the understanding of the unique ecosystem and marine environment through the great Paleozoic-Mesozoic transition. The anachronistic facies characterized by vermicular limestone have been documented in many localities in South China and occur at various horizons of the Lower Triassic. Most types of re- ported distinctive sediments over the world have been observed in the Lower Triassic of South China. This provides an excellent opportunity for understanding the Early Triassic environment and its co- evolution with the biotic recovery. Among the anachronistic facies the vermicular limestone is the most characteristic and common distinctive sediments in the Lower Triassic of South China but has received relatively few investigations. Taking it as a case study, we will detail the variation of vermicular limestone and its stratigraphic distribution in the Three Gorges area, Hubei Province. The investigation on the vermicular limestone and other distinctive sediments from the Lower Triassic of South China further indicates that the appearance of anachronistic facies immediately following the mass extinction and the elimination from normal shallow marine facies with the radiation of Mesozoic marine faunas imply the natural response of the sedimentary systems and ecosystems to the great Paleozoic-Mesozoic transitional events and their induced harsh environments. Therefore, the ups and downs of the anachronistic facies may act as a proxy for the evolution of ecosystems independent of fossil analyses. | XiaoMing Zhao (1) (2) JinNan Tong (1) HuaZhou Yao (2) KeXin Zhang (1) Chen Zq (3) | 2008 | Science China Earth Sciences2008，51，11： | 14 |
| 6 | Carbide Behavior during High Temperature Creep in DZ40M Co-base Superalloy显示文摘The carbide behavior of a directionalIy solidified Co-base superalloy DZ40M has been investigatedafter creep at 700° and 900°. During the high temperature creep, a great amount of secondary carbide, M3C6 precipitated in alloy matrix. At 700℃, the M23C6 precipitation occurred in slip bands, indicating that it was stress-induced, while at 900℃, M23C6 formed surrounding the primary carbides, which is a characteristic of thermally aged alloy. The M23C6 particles pinned up dislocations and subgrain boundaries, strengthening the alloy matrix effectively. The creep crack initiation of DZ40M alloy was exclusively related to the primary carbides. The fracture of the primary carbide and the crack at the interface between them and matrix resulted in the crack formation. Furthermore, it was found that at 900℃, the surface of specimens was oxidized severely and the preferentially oxidized primary carbides acted as crack initiation sites. | Jiang, WH Yao, XD Guan, HR Hu, ZQ | 1999 | Journal of Materials Science & Technology1999，15，6： | 6 |
| 7 | On abiogenic natural gas显示文摘NATURAL gases usually refer to the inflammable gases dominated by methane from the angle of research on energy gases. Three genetic types of natural gases can be recognized according to the process of methane generation: (ⅰ) biogenic (bacterial) gas, mainly the gas formed by the decomposition of organic matter in sediments under the action of anaerobic bacteria; (ⅱ) thermogenic gas, mainly the gas formed by the degradation of organic matter in sediments under the action of certain temperature and pressure; (ⅲ) abiogenic gas, mainly the | Wang, XB Li, CY Chen, JF Xia, XY Guo, ZQ Xie, HS | 1997 | Chinese Science Bulletin1997，42，16： | 5 |
| 8 | A CRACK CLOSURE MODEL FOR BRITTLE ROCK SUBJECTED TO COMPRESSIVE-SHEAR LOADING显示文摘1INTRODUCTIONCompressionshearfractureofrockwasinvestigatedbymanyresearchers,Raoetal[1]studiedthisfailuremodeusingfourpointb... | Chen, F Sun, ZQ Xu, JC | 1999 | 中国有色金属学会会刊:英文版1999，9，2： | 4 |
| 9 | Self-organization of Gold Nanoparticles Protected by 9-(5-Thiopentyl)-carbazole显示文摘Through the reduction of [AuCl4]- by aqueous sodium borohydride in the presence of 9-(5-thiopentyl)-carbazole, the gold nanoparticles has been prepared and characterized. | Wang, S Li, YL Du, CM Shi, ZQ Xiao, SX Fang, HJ Zhu, DB | 2001 | Chinese Chemical Letters2001，12，12： | 4 |
| 10 | Discovery of virus pathogen from soft-shelled turtle Trionyx sinesis显示文摘THE soft-shelled turtle Trionyx sinesis, because of its nutritional and medicinal values, | Zhang, QY Li, ZQ Jiang, YL Liang, SC Gui, JF | 1997 | Chinese Science Bulletin1997，42，6： | 3 |
| 11 | Morphology Characteristics of Nd-rich Phase Particles in Melt-quenched Ti-5Al-4Sn-2Zr-1Mo-0.25Si-1Nd Alloy显示文摘The morphology of the melt-equenched Ti-5Al-4Sn-2Zr-1Mo-9.25Si-1Nd alloy is uniformly distributed Nd-rich phase particles in matrix. The particles within grains are spherical, and the particles at grain boundaries are elliptical. The Nd-rich phase particle calculated is 6.6 nm in diameter, which is within the 6-15 nm range of average particle diameter experimentally ob served in the alloy The practical interfsce velocity (0.5 m/s) is much greater than the critical velocity (0.15 m/s), hence the Nd-rich phase particles are trapped by the liquid-solid | LI, GP LI, D LIU, YY HU, ZQ | 1995 | Journal of Materials Science & Technology1995，11，6： | 3 |
| 12 | Powder Microstructure and Overlay Coating Property ofNiCrAlY Alloy显示文摘这被显示出更好(20-30 亩 m ) 粉末粒子经历快速的复辉和热抽取到导致微细胞的结构的环境,而更粗糙(40-50 亩 m ) 因为慢冷却跟随的复辉,粉末粒子展出粗糙的细胞、树枝状的混合结构。另外,这也被显示越好粉末粒子尺寸,越 higher 机械性质并且冶金热稳定性过分,涂层由把同样分裂成原子的粉末扔了,它大概为粉末的好尺寸部分被归因于稠密的好谷物结构和氧化物层的形成。(编辑作者摘要) 9 个裁判员。 | Chang, XC Wang, JQ Hao, YY Hou, WL Hu, ZQ | 1998 | Journal of Materials Science & Technology1998，14，4： | 3 |
| 13 | Simultaneous multi-tear exclusion:an optimal strategy for type B thoracic aortic dissection initially proved by a single center's 8 years experience显示文摘背景 Endovascular 接枝stent 广泛地被用来对待胸的大动脉的 dissection.However ,很少信息都不关于跟随八年用为斯坦福的治疗的同时的多眼泪排除的经验打 B 胸的大动脉的解剖导致到1月2006,29日类型 B 胸的大动脉的解剖病人的从1998年9月的没有不利 events.Methods 的成功的大动脉的改变的多重 tears.This 报告细节的同时的排除的结果是可得到的( 24 个人, 5 | YUAN Liang-xi BAO Jun-min ZHAO Zhi-qing FENG Xiang OU Le-feng FENG Rui LU Qing-sheng MEI Zhi-jun JING Zai-ping Department of Vascular Surgery,Changhai Hospital,Second Military Medical University Institute of Vascular Surgery of Chinese People’s Liberation Army Clinic Center of Vascular Diseases of Shanghai National Key Department of Vascular Surgery of China Shanghai 200433,China (Yuan LX,Bao JM,Zhao ZQ,Feng X,Ou LF,Feng R,Lu QS,Mei ZJ and Jing ZP) | 2007 | Chinese Medical Journal2007，，24： | 3 |
| 14 | Expression of gap junctions and inhibition of cell growth in communication-defected cells after transfection with gap junction gene Cx43 cDNA显示文摘Gap junctions form intercellular channels for direct exchange of metabolites and second messengers between adjacent cells. The existence of a multi-gene family encoding gap junction proteins, i. e. the connexins (Cx), has been recently demonstrated. Despite the overall sequence homologies and a similar predicted structural motif, their functional properties differ in various tissues. Because of coexpression of two or more connexin proteins in one tissue, determination of properties specific for each connexin is complicated. The regulation of expression of gap junctions and their roles in cellular activities remain mostly unelucidative. Controlled manipulation of connexin molecules in Xenopus oocyte expression system has been use- | Zhang, ZQ Lin, ZX Wang, NQ Han, YL | 1997 | Chinese Science Bulletin1997，42，5： | 3 |
| 15 | Ischemic brain injury is mediated by the activation of poly (ADP- ribose)polymerase显示文摘 | ENDRES M Wang ZQ Namura S | | 0，，： | 2 |
| 16 | Changing trends of surgical treatment of hilar bile duct cancer:clinical and experimental perspectives显示文摘HISTORICAL POINT OF VIEWCarcinoma of the confluence of the hepatic ductshas been thought to be a rare disease until recently.Carcinoma of the large hepatic ducts was rarelydiagnosed correctly premorterned.Because of itsdeeply seated location,resection was once thoughtto be impossible.In 1957,Altemeier reported | Huang ZQ Zhou NX Wang DD Lu JG Chen MY | 2000 | World Journal of Gastroenterology2000，6，6： | 2 |
| 17 | PHASE TRANSFORMATION OF Al-Ti COATINGS ON Co-BASE SUPERALLOY DZ40M DURING HIGH TEMPERATURE OXIDATION显示文摘INTRODUCTIONThereisaseriousproblemofhightemperatureoxidationonturbinecomponents,hence,variouscoatingswithaluminidearemanufac... | Liu, PS Sun, XF Jin, T Guan, HR Hu, ZQ | 1998 | 中国有色金属学会会刊:英文版1998，8，4： | 2 |
| 18 | Chromosomal aberrations andsister-chromatid exchanges of lymphocytes of workers exposed to sulphur dioxide显示文摘 | Meng ZQ Zhang LZ | 1990 | Mutat Res1990，241，： | 2 |
| 19 | Observation of frequenciesof lymphocytes with micronuclei in human peripheral blood cultures from workers in a sulphuric acid factory显示文摘 | Meng ZQ Zhang LZ | 1990 | Environ Mol Mutagen1990，15，： | 2 |
| 20 | Reperfusion induces myocardial apoptotic cell death显示文摘 | Zhao ZQ Nakamura M Wang NP | 2000 | Cardiovasc Res2000，45，3： | 2 |
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