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| 1 | Drug-induced liver injury: Do we know everything?显示文摘Interest in drug-induced liver injury(DILI) has dramatically increased over the past decade, and it has become a hot topic for clinicians, academics, pharmaceutical companies and regulatory bodies. By investigating the current state of the art, the latest scientific findings, controversies, and guidelines, this review will attempt to answer the question: Do we know everything? Since the first descriptions of hepatotoxicity over 70 years ago, more than 1000 drugs have been identified to date, however, much of our knowledge of diagnostic and pathophysiologic principles remains unchanged. Clinically ranging from asymptomatic transaminitis and acute or chronic hepatitis, to acute liver failure, DILI remains a leading causes of emergent liver transplant. The consumption of unregulated herbal and dietary supplements has introduced new challenges in epidemiological assessment and clinician management. As such, numerous registries have been created, including the United States Drug-Induced Liver Injury Network, to further our understanding of all aspects of DILI. The launch of Liver Tox and other online hepatotoxicity resources has increased our awareness of DILI. In 2013, the first guidelines for the diagnosis and management of DILI, were offered by the Practice Parameters Committee of the American College of Gastroenterology, and along with the identification of risk factors and predictors of injury, novel mechanisms of injury, refined causality assessment tools, and targeted treatment options have come to define the current state of the art, however, gaps in our knowledge still undoubtedly remain. | Tamara Alempijevic Simon Zec Tomica Milosavljevic | 2017 | World Journal of Hepatology2017，9，10： | 13 |
| 2 | 通过轧制纯铝箔和阳极铝箔制备多层铝基复合材料(英文)显示文摘介绍了一种以商业纯铝箔为基体的多层复合材料的加工过程、组织结构和力学性能。采用热轧制交替排布的纯铝和阳极铝箔制备多层复合材料;此外,采用同样的工艺制备纯铝箔多层复合材料。在这两种情况下,均得到紧实致密的多层复合材料。为了研究复合材料的微观组织演变和力学性能,分别进行了光学和扫描电镜(SEM)、能谱(EDS)、X射线衍射(XRD)分析以及硬度、拉伸和三点弯曲试验。微观组织表征显示,阳极铝复合材料铝基体中平行分布着棒状Al_2O_3颗粒,而且铝箔界面间生成少量粗大颗粒。两种复合材料的硬度、强度、弹性模量和抗弯强度均高于纯铝材料的,而延展性明显降低。与纯铝箔多层复合材料相比,阳极铝箔多层复合材料具有较高的强度和弹性模量以及较低的延展性。材料的断裂失效方式与延展性的变化一致。 | Milan T.JOVANOVI? Nenad ILI? Ivana CVIJOVI?-ALAGI? Vesna MAKSIMOVI? Slavica ZEC | 2017 | Transactions of Nonferrous Metals Society of China2017，27，9： | 2 |
| 3 | A novel application of the principles of linear elastic fracture mechanics (LEFM) to the fatigue behavior of tendon tissue显示文摘 | Adeeb S M Zec M L Thornton G M | 2004 | J Biomech Eng2004，126，5： | 1 |
| 4 | Alzheimer disease assessment scale:a subtest analysis 显示文摘 | Zec R F Landreth E S Vicari S K | 1992 | Alzheimer Dis Assoc Disord1992，6，3： | 1 |
| 5 | The effect of temperature on the properties of hdroxyapatite precipitated form calcium hdroxide and phosphoric acid 显示文摘 | IAZIC S ZEC S MILIEVIC N | 2001 | Thermochimica Acta2001，37，4： | 1 |
| 6 | TiAl-A new high temperature material for turbocharger rotors显示文摘 | DIMCIC B JOVANOVIC M T BOBIC I ZEC S TADIC S | 2004 | Materials Science Forum2004，，： | 1 |
| 7 | The impact of lem- poral variability of biochemical markers PAPP-A and free beta-hCG on the specificity of the first-trimester Down syndrome screening: d Croa- tian retrospective study显示文摘 | Tislaric-Medenjak D Zec 1 Simundic AM | 2010 | BMC Res Notes2010，3，： | 1 |
| 8 | Anatomic relationships of the human nucleus paragigantocellularis lateralis: a Dil labeling study显示文摘 | Zec N Kinney H C | 2001 | Auton Neurosci2001，89，： | 1 |
| 9 | Transition of gamma-Al203 into alpha-Al203 during vibro milling 显示文摘 | KOSTIC E KISS S J ZEC S BOSKOVIC S | 2000 | Powder Technology2000，107，12： | 1 |
| 10 | Anatomic relationships of the human arcuate nucleus of the medulla: a DiI-labeling study显示文摘 | Zec N Filiano J J Kinney H C | 1997 | J Neuropathol Exp Neurol1997，56，： | 1 |
| 11 | Anatomic relationships of the human nucleus of the solitary tract in the medulla oblongata: a DiI labeling study显示文摘 | Zec N Kinney H C | 2003 | Auton Neurosci2003，105，： | 1 |
| 12 | Auxiliary Reduction without Empty Categories:A Prosodic Account显示文摘 | INKELAS SHARON and ZEC DRAGA | 1993 | Working Papers of the Cornell Phonetics Laboratory1993，，8： | 1 |
| 13 | SeaWinds beam and slice balance using data over Amazonian rainforest显示文摘 | Zec J Jones W L Long D G | 2000 | IGARSS2000，5，： | 1 |
| 14 | Phase-transformation kinetic in triphasic cordierite gel 显示文摘 | PETROVIC R JANACHOVIC D ZEC S | 2001 | J Mater Res2001，16，2： | 1 |
| 15 | BSD Network stack virtualization显示文摘 | Zec M | 2002 | BSDCon Europe Amsterdam Nov2002，，： | 1 |
| 16 | The effect of temperature on theproperities of hydroxyapatite precipitated from calcium hydroxide and phosphoric acid显示文摘 | Lazic S Zec S Miljevie N | 2001 | Thermochimica Acta2001，374，1： | 1 |
| 17 | The Effect of Temperature on the Properities of Hydroxyapatite Precipitated from Calcium Hydroxide and Phosphoric Acid显示文摘 | Lazic S Zec S Miljevic N | 2001 | Thermochimica Acta2001，374，： | 1 |
| 18 | The effect of temperature on the properties of hdroxyapatite precipitated form calcium hdroxide and phosphoric acid 显示文摘 | LAZIC S ZEC S MILJEVIC N | 2001 | Thermochimica Acta2001，37，4： | 1 |
| 19 | The impact of temporal variability of biochemical markers PAPP-A and free beta-hCG on the specificity of the first-trimester Down syndrome screening:a Croatian retrospective study显示文摘 | Tislaric-Medenjak D Zec I Simundic AM | 2010 | BMC Res Notes2010，14，3： | 1 |
| 20 | Orbital Swelling as a Sign of Live Dirophilaria repens in Subconjunctival Tissue显示文摘 | Mirjana P. Dujic Bora S. Mitrovic Ivanka M. Kranjcic Zec | 2003 | Scandinavian Journal of Infectious Diseases2003，，6： | 1 |
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