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| 1 | PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix显示文摘Biofilms 是在细胞外的矩阵嵌入的微生物的联系表面的社区。Exopolysaccharide 是在维持 biofilm 建筑学并且保护居民 biofilm 细菌免受抗菌剂和主人免疫者攻击的伤害的细胞外的矩阵的一个批评部件。然而,指向矩阵 exopolysaccharides 的自我生产的因素,仍然糟糕被理解。这里,我们显示出那 PslG,在 Pseudomonas aeruginosa 涉及关键 biofilm 矩阵 exopolysaccharide Psl 的合成的蛋白质,阻止 biofilm 形成并且拆卸存在在外长地供应的在 nanomolar 集中的分钟以内的 biofilms。PslG 的水晶结构显示 endoglycosidase 的典型特征。PslG 主要破坏 Psl 矩阵从 biofilms 驱散细菌。PslG 处理显著地提高 biofilm 敏感到抗菌素和巨噬细胞房间,导致在一只老鼠的改进 biofilm 清理植入感染模型。而且, PslG 对大量 Pseudomonas 种类显示出 biofilm 抑制和拆卸活动,显示它在与 biofilm 相关的复杂并发症作斗争的大潜力。 | Shan Yu Tiantian Su Huijun Wu Shiheng Liu Di Wang Tianhu Zhao Zengjun Jin Wenbin Du Mei-Jun Zhu Song Lin Chua Liang Yang Deyu Zhu Lichuan Gu Luyan Z Ma | 2015 | Cell Research2015，25，12： | 13 |
| 2 | Potent antitumor efficacy of an E1B 55kDa-deficient adenovirus carrying murine endostatin in hepatocellular carcinoma显示文摘 | Li G Sham J Yang J Su C Xue H Chua D Sun L Zhang Q Cui Z Wu M Qian Q | 2005 | 第二军医大学学报2005，26，11： | 9 |
| 3 | The Surface Energy Balance System (SEBS) for estimation of turbulent heat fluxes显示文摘 | Su Z | 1999 | Hydrology and Earth System Sciences1999，，20： | 3 |
| 4 | The Surface Energy Balance System (SEBS) for estimation of turbulent heat fluxes显示文摘 | Su Z | 1999 | Hydrology and Earth System Sciences1999，，20： | 2 |
| 5 | The valence change from RE3+ (RE=Eu,Sm,Yb) in SrB4O7:RE prepared in air and the spectral properties of RE2+显示文摘 | PEI Z W SU Q ZHANG J Y | 1993 | Journal of Alloys and Compound1993，198，： | 2 |
| 6 | Study on scaling of mechanically alloyed and hot pressed NbCr2 Laves phase at 1 200 ℃ in air显示文摘 | ZHENG H Z LU S Q SU Q QUAN F J | 2008 | Int J Refr Metals Hard Mater2008，26，1： | 1 |
| 7 | Shrub facilitation of desert land restoration in the Horqin Sand Land of Inner Mongolia显示文摘 | ZHAO H L ZHOU R L SU Y Z | 2007 | Ecological Engineering2007，31，： | 1 |
| 8 | Study of polystyrene and acrylomtrile-styrene copolymer as special beta-nucleating agents to induce the crystallization of isotactic polypropylene 显示文摘 | SU Z Q DONG M GUO Z X | 2007 | Macromolecules2007，40，： | 1 |
| 9 | Long-term effect of fertilizer and manure application on soil-carbon sequestration and soil fertility under the wheat-wheat-maize cropping system in northwest China 显示文摘 | SU Y Z WANG F SUO D R | 2006 | Nutrient Cycling in Agroeeosystems2006，75，： | 1 |
| 10 | High level expression of human endostatin in Pichia pastoris using a synthetic gene construct 显示文摘 | Su Z Wu X Feng Y | 2007 | Appl MicrobiolBiotechnol2007，73，6： | 1 |
| 11 | Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis 显示文摘 | Sauane M Su Z Z Gupta P | 2008 | Proc Natl Acad Sci U S A2008，105，： | 1 |
| 12 | Effects of formulation parameters on encapsulation efficiency and release behavior of risperidone poly ( D, L-lactide-co-glycolide) microsphere 显示文摘 | SU Z SUN F SHI Y | 2009 | Chem Pharm Bull2009，57，11： | 1 |
| 13 | Cloning and expression of complementary DNA encoding an antigen of Trichinella spiralis显示文摘 | Su X Z Prestwood A K McGraw R A | 1991 | MolBiochemParasitol1991，45，： | 1 |
| 14 | Standardizing catch and effort data of the Taiwanese distant-water longline fishery in the western and central Pacific Ocean for bigeye tuna, Thunnus obesus显示文摘 | Su N J Yeh S Z Sun C L Punt A E Chen Y Wang S P | | Fisheries Research0，90，13： | 1 |
| 15 | Testing structural change in time-series nonparametric regression models 显示文摘 | Su L J and Xiao Z J | 2008 | Statistics and Its Interface2008，，1： | 1 |
| 16 | A machine vision system for on-line removal of contaminants in wool 显示文摘 | Su Z W Tian G Y Gao C H | 2006 | Mechatronics2006，16，3： | 1 |
| 17 | Methionine aminopeptidase (type-2)is the common target for angiogenesis inhibitors AGM-1470 and o-valicin显示文摘 | Griffith EC Su Z Turk BE | 1997 | Chem Biol1997，4，6： | 1 |
| 18 | mda-7(IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK显示文摘 | Sarkar D Su Z Z Lebedeva I V | 2002 | Proc Natl Acad Sci USA2002，99，10： | 1 |
| 19 | 2-Mercaptobenzothiazole-bonded silica gel as selective adsorbent for preconcentration of gold, platinum and palladium prior to their simultaneous inductively coupled plasma optical emission spectrometric determination显示文摘 | Pu Q S Su Z X Hu Z D | 1998 | J At Anal Spectrom1998，13，4： | 1 |
| 20 | Application of small angle neutron scattering to the in situ study of protein fouling on ceramic membranes 显示文摘 | Su T J Lu J R Cui Z R | 1998 | Langmuir1998，14，： | 1 |
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