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| 1 | 尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。 | Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 29 |
| 2 | Lancet:世界心脏联盟全球心血管疾病预防展望显示文摘动脉粥样硬化性心血管疾病是世界头号致死致残因素,不成比例地影响着中低收入国家(LMIC)的居民。二十世纪六七十年代,心血管疾病被视为高收入国家的常见病,此后通过采取更好的预防措施(如改变生活方式、控制风险因素等),并广泛应用简单有效的紧急事件处理和二级预防措施,心血管疾病的年龄标准化死亡率得以减半。然而,即便在发达国家,所采取的这些行之有效的策略仍远远不够,如果在大多数高收入国家中推广,未来二十年心血管疾病的发生率将进一步降低。 | Yusuf S Wood D Ralston J Reddy KS | 2015 | 疾病监测2015，30，5： | 14 |
| 3 | Non-classical phenotypes of autoimmune hepatitis and advances in diagnosis and treatment显示文摘Non-classical manifestations of autoimmune hepatitis can delay diagnosis and treatment.Our aims were to describe the clinical phenotypes that can confound the diagnosis,detail scoring systems that can ensure their recognition,and outline advances in treatment that can improve their outcome.Prime source and review articles in English were selected through Medline from 1970-2008 and assimilated into personal libraries spanning 32 years.Acute severe or asymptomatic presentations and atypical histological findings,including centrilobular zone 3 necrosis and concurrent bile duct changes,are compatible with the diagnosis.Cholangiographic abnormalities may be present in children and adults with the disease,and autoimmune hepatitis must be considered in patients without autoantibodies or with antimitochondrial antibodies and no other cholestatic features.Asymptomatic patients frequently become symptomatic;mild disease can progress;and there are no conf ident indices that justify withholding treatment.Two diagnostic scoring systems with complementary virtues have been developed to evaluate patients with confusing features.Normal liver tests and tissue constitute the optimal end point of treatment,and the f irst relapse is an indication for long-term azathioprine therapy.Cyclosporine,tacrolimus and mycophenolate mofetil are promising salvage therapies,and budesonide with azathioprine may be a superior frontline treatment.We conclude that the non-classical phenotypes of autoimmune hepatitis can be recognized promptly,diagnosed accurately,and treated effectively. | Albert J Czaja Yusuf Bayraktar | 2009 | World Journal of Gastroenterology2009，15，19： | 4 |
| 4 | 血脂、脂蛋白和载脂蛋白作为心肌梗死风险标志物(INTER-HEART研究):在52个国家进行的一项病例对照研究显示文摘背景载脂蛋白作为冠心痛的标志物是否优于血脂和脂蛋白,目前存在广泛争议。本研究旨在对载脂蛋白和胆固醇作为急性心肌梗死风险指标进行比较.
方法在52个国家的12461例急性心肌梗死患者和14637例年龄(±5岁)、性别匹配的对照者中进行了一项有关急性心肌梗死的大型、标准化病例对照研究。获得了9345例急性心肌梗死患者和12120例对照者的非空腹血液样本。测定了血脂、脂蛋白和载脂蛋白浓度,并计算了胆固醇和栽脂蛋白比值通过比较五分位数的上四位与最低位,计算每一总体测值和每一种族组的优势比(0R)及其95%CI以及人群归因危险度(PAR)。
结果载脂蛋白B100(ApoB)/载脂蛋白A1(ApoA1)比值的PAR最高(54%),其每一标准差差别的OR最高(1.59,95%CI1.53~1.64)。LDL胆固醇/HDL-胆固醇比值的PAR为37%;总胆固醇/HDL-胆固醇的PAR为32%,其显著低于ApoB/A1比值的PAR(P〈0.0001)。这些结果在所有种族组、男女两性组及所有年龄组均一致。
结论在所有种族组、男女两性组及所有年龄组,非空腹ApoB/A1比值在评估急性心肌梗死风险方面优于任何胆固醇比值,其应当被引入全世界的临床实践中。 | Matthew J McQueen Steven Hawken Xingyu Wang Stephanie Ounpuu Allan Sniderman Jeffrey Probstfield Krisela Steyn John E Sanderson Mahammad Hasani Emilia Volkova Khawar Kazmi Salim Yusuf 郭战宏(译) | 2008 | 世界临床医学2008，2，6： | 3 |
| 5 | Effect of PSC 833,an in-hibitoRof P-glycoprotein on N-methyl-N-nitrosourea induced mammary carcinogenesis in rats显示文摘 | Kankesan J Vanama R Yusuf A | 2004 | Carcinogenesis2004，25，3： | 1 |
| 6 | Overcoming the limitations of current meta-analysis of randomized controlled trials显示文摘 | Yusuf S | 1998 | Lancet1998，351，： | 1 |
| 7 | Telmisartan, ramipril, or both in patients at high risk for vascular events显示文摘 | Yusuf S Teo KK Pogue J | 2008 | N Engl J Med2008，358，15： | 1 |
| 8 | Dabigatran versus warfarin in patients with atrial fibrillation 显示文摘 | Connolly S J Ezekowitz MD Yusuf S | 2009 | N Engl J Med2009，361，12： | 1 |
| 9 | Bata blockade during and after myocardial infarction:an overview of the randomized trials显示文摘 | Yusuf S Peto R Lewis J | 1985 | Prog Cardiovasc Dis1985，27，5： | 1 |
| 10 | Prevention of Heart Failure in Patients in the Heart Outcomes Prevention Evaluation (HOPE) Study显示文摘 | LinksArnold JM Yusuf S Young J | 2003 | Circulation2003，107，9： | 1 |
| 11 | Renal insuf- ficiency as a preditor of cardiovascular outcomes and the impact of ramipril~ the HOPE radomized trial显示文摘 | Mann J F Gerstein H C Pogue J Bosch J Yusuf S | 2001 | Ann Intern Med2001，134，： | 1 |
| 12 | Vitamin E supplementation and cardiovascular events in high-risk patients:the Heart Outcomes Prevention Evaluation Study Investigators显示文摘 | Yusuf S Dagenais G Pogue J | 2000 | N Engl J Med2000，342，： | 1 |
| 13 | Telmisartan, ramipril, or both in patients at high risk for vascular events显示文摘 | Yusuf S Teo KK Pogue J etal | 2008 | N Engl J Med2008，358，15： | 1 |
| 14 | Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes(RIVAL):a randomised,parallel group,multicentre trial显示文摘 | Jolly SS Yusuf S Cairns J | 2011 | Lancet2011，377，9775： | 1 |
| 15 | Homocysteine lowering with folio acid B vitamins in vascular disease显示文摘 | Lonn E Yusuf S Arnold M J | 2006 | N Engl J Med2006，354，15： | 1 |
| 16 | Effects of pretreatment with clo- pidogrel and aspirin followed by long-term therapy in patients undergo- ing percutaneous coronary intervention :the PCI-CURE study显示文摘 | Mehta SR Yusuf S Peters R J | 2001 | Lan- cet2001，358，9281： | 1 |
| 17 | Radial versus femoral access for cor-onary angiography and intervention in patients with acute coronary syn-dromes (RIVAL) ; a randomized, parallel group, multicenter trail显示文摘 | Jolly SS Yusuf S Caims J | 2011 | Lancet2011，377，： | 1 |
| 18 | Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose:randomised controlled trial 显示文摘 | Gerstein HC Yusuf S Bosch J | 2006 | Lancet2006，368，9541： | 1 |
| 19 | Radial versus femoral access for coronary angiography and intervention in patients with acute cornary syndromes (RIVAL):a randomised,parallel group, muhicentre trial 显示文摘 | Jolly SS yusuf Cairns J | 2011 | Lancet2011，577，： | 1 |
| 20 | Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial 显示文摘 | Jolly SS Yusuf S Cairns J | 2011 | Lancet2011，377，9775： | 1 |
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