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| 1 | 卵巢原发性子宫内膜间质肉瘤27例临床病理分析:形态学和生物学行为特征类似于子宫低级别子宫内膜间质肉瘤显示文摘原发性子宫外的子宫内膜间质肿瘤非常罕见,作者报道27例卵巢原发性子宫内膜间质肉瘤的临床病理特征。患者年龄38—76岁,平均56岁。20例为单侧卵巢病变,7例累及双侧卵巢。肿瘤直径1—20cm,平均9.5cm。实性区域切面呈典型的黄褐色,6例伴出血和(或)坏死, | Oliva E Egger J F Young R H 康锶鹏 余英豪 | 2014 | 临床与实验病理学杂志2014，30，7： | 11 |
| 2 | Dementia and osteoporosis in a geriatric population: Is there a common link?显示文摘AIM To determine the existence of a common pathological link between dementia and osteoporosis through reviewing the current evidence base. METHODS This paper reviews the current literature on osteoporosis and dementia in order to ascertain evidence of a common predisposing aetiology. A literature search of Ovid MEDLINE(1950 to June 2016) was conducted. The keywords 'osteoporosis', 'osteoporotic fracture', 'dementia' and 'Alzheimer's disease'(AD) were used to determine the theoretical links with the most significant evidence base behind them. The key links were found to be vitamins D and K, calcium, thyroid disease, statins, alcohol and sex steroids. These subjects were then searched in combination with the previous terms and the resulting papers manually examined. Theoretical, in vitro and in vivo research were all used to inform this review which focuses on the most well developed theoretical common causes for dementia(predominantly Alzheimer's type) and osteoporosis.RESULTS Dementia and osteoporosis are multifaceted disease processes with similar epidemiology and a marked increase in prevalence in elderly populations. The existence of a common link between the two has been suggested despite a lack of clear pathological overlap in our current understanding. Research to date has tended to be fragmented and relatively weak in nature with multiple confounding factors reflecting the difficulties of in vivo experimentation in the population of interest. Despite exploration of various possible mechanisms in search for a link between the two pathologies, this paper found that it is possible that these associations are coincidental due to the nature of the evidence available. One finding in this review is that prior investigation into common aetiologies has found raised amyloid beta peptide levels in osteoporotic bone tissue, with a hypothesis that amyloid beta disorders are systemic disorders resulting in differing tissue manifestations. However, our findings were that the most compelling evidence of a common yet independent aetiology lies in the APOE4 allele, which is a well-established risk for AD but also carries an independent association with fracture risk. The mechanism behind this is thought to be the reduced plasma vitamin K levels in individuals exhibiting the APOE4 allele which may be amplified by the nutritional deficiencies associated with dementia, which are known to include vitamins K and D. The vitamin theory postulates that malnutrition and reduced exposure to sunlight in patients with AD leads to vitamin deficiencies. CONCLUSION Robust evidence remains to be produced regarding potential links and regarding the exact aetiology of these diseases and remains relevant given the burden of dementia and osteoporosis in our ageing population. Future research into amyloid beta, APOE4 and vitamins K and D as the most promising aetiological links should be welcomed. | Candice L Downey Adam Young Emily F Burton Simon M Graham Robert J Macfarlane Eva-Maria Tsapakis Eleftherios Tsiridis | 2017 | World Journal of Orthopedics2017，8，5： | 6 |
| 3 | The oxidative dehydrogenation of ethane over catalysts containing mixed oxides of molybdenum and vanadium显示文摘 | Thorsteinson E M Wilson T P Young F G | 1978 | J Catal1978，52，： | 2 |
| 4 | A method for rapid determination of lactose显示文摘 | Teles F F Young C K Stull J W | 1978 | J Dairy Sci1978，61，： | 2 |
| 5 | Laser Induced Periodic Surface Damage and Radiation Remnants 显示文摘 | YOUNG J F SIPE J E PRESTON J S | 1982 | Appl Phys Lett1982，41，： | 1 |
| 6 | Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community based study显示文摘 | Nieto F J Young TB Lind BK Shahar E Samet JM Redline S D’ Agostino RB Newman AB Lebowitz MD Picketing TG | 2000 | JAMA2000，283，： | 1 |
| 7 | More than folding:localized functions of cytosolic chapemmes显示文摘 | YOUNG J C BARRAL J M HARD U F | 2003 | Trends Biochem Sci2003，28，： | 1 |
| 8 | Aplastic anaemia in the Orient 显示文摘 | Young NS Issaragrisil S Chieh CW Takaku F | 1986 | Br J Haematol1986，62，1： | 1 |
| 9 | B-type natriuretic peptide exerts broad functional opposition to transforming growth factor beta in primary human cardiac frbroblasts: fi- brosis,myofibroblast conversion,proliferation, and inflamma- tion显示文摘 | Kapoun AM Liang F ()'Young G | 2004 | Circ Res2004，94，4： | 1 |
| 10 | Reactiva-tion of peroxi-some proliferator- activated receptora is associat-ed with contractile dysfunction in hypertrophied rat heart 显示文摘 | YOUNG M E LAWS F A GOODWIN G W | 2001 | JBiol Chem2001，276，44： | 1 |
| 11 | Boron nitride substrates for high-quality graphene electronics显示文摘 | Dean C R Young A F Meric I | 2010 | Nat Nnotechn2010，5，10： | 1 |
| 12 | Transformation and transfection in lysogenic strains of Bacillus subtilis 168显示文摘 | Yasbin R E Wilson G A Young F E | 1973 | Journal of Bacteriology1973，113，2： | 1 |
| 13 | HMM based architecture for faceidentification 显示文摘 | SAMARIA F YOUNG S | 1994 | Image and Computer Vision1994，12，8： | 1 |
| 14 | Toll(TLR4)expression in cardiac myocytes in normal and failing myocardium显示文摘 | Stefan F Lester K Young DK | 1999 | J Clin Invest1999，104，： | 1 |
| 15 | A Three-dimensional Analysis of Marine Radar Images for the Determination of Ocean Wave Directionality and Surface Currents 显示文摘 | YOUNG I R ROSENTHAL W ZIEMER F | 1985 | Journal of Geophysical Research1985，90，1： | 1 |
| 16 | Relativistic Hartree condition for magnetrons:Theory and comparison with experiments显示文摘 | Lovelace R V Young T F T | 1985 | Phys Fluids1985，28，8： | 1 |
| 17 | Treatment of fractures of the head and neck of the radius and slipped radial epiphysis in children显示文摘 | Schwartz RP Young F | 1933 | Surg Gynecol Obstet1933，57，： | 1 |
| 18 | B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts : fibrosis, myoflbroblast conversion, proliferation, and inflammation显示文摘 | Kapoun AM Liang F O'Young G | 2004 | Circ Res2004，94，4： | 1 |
| 19 | Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response显示文摘 | Young D F Didcock L Goodbourn S | 2000 | Virology2000，269，： | 1 |
| 20 | Degradations in Gbit/s DFB lasertransmission systems due to phase-to-intensity noise conversion by multiple reflectionpoints 显示文摘 | 22,GIMLETT J L YOUNG J SPICER R F | 1988 | Electronics Lett1988，24，7： | 1 |
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