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| 1 | IDH突变的弥漫性和间变性星形细胞瘤具有相同的发病年龄和极小的生存期差异:一个WHO分级的问题显示文摘WHO(2007)中枢神经系统肿瘤分类中列出WHOⅡ级的弥漫性星形细胞瘤(A Ⅱ WHO 2007)和WHOⅢ级的间变性星形细胞瘤( AA Ⅲ WHO 2007)之间的区别。 A Ⅱ WHO (2007)的患者与AA Ⅲ WHO (2007)的患者相比显著年轻、生存期明显较长。迄今为主,分级和分类仅仅依靠形态学而未考虑IDH这一预后相关分子标记的状态。作者发现,对于IDH突变的星形细胞瘤而言,WHO(2007)的分级系统对预后的提示意义较差。检测来自3个独立的病例系列共1360例成人弥漫性星形细胞肿瘤的年龄分布和生存时间,其中包括683例Ⅱ级IDH突变型星形细胞瘤( A Ⅱ IDHmut)、562例IDH突变型的间变性星形细胞瘤( AA Ⅲ IDHmut)和115例IDH 突变的胶质母细胞瘤( GBM IDHmut )。 A ⅡIDHmut和 AA Ⅲ IDHmut的患者显示具有相同的发病年龄(36~37岁),而两级别之间的生存时间差异小于 WHO (2007)的报道(A Ⅱ IDHmut 中位生存时间为10.9年,AAⅢIDHmut为9.3年)。作者分析提示AⅡWHO2007与AAⅢ WHO2007年龄分布和生存时间的差异主要取决于 IDH非突变型肿瘤所占的比例。这些数据结果对目前实行的星形细胞瘤分级和危险分层提出了重大挑战,并可能对 IDH突变型星形细胞瘤的治疗管理产生深远的影响。 | David E Yasin M Daniel S 李晓玲 王行富 | 2015 | 临床与实验病理学杂志2015，31，7： | 17 |
| 2 | MUC4 and ErbB2expression in squamous cell carcinoma of the upperaerodigestivetract:correlation with clinical outcomes显示文摘 | Weed DT Gomez-Fernandez C Yasin M | 2004 | Laryngoscope2004，14，82101： | 1 |
| 3 | Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R显示文摘 | Sivarajah A Collino M Yasin M | 2009 | Shock2009，31，3： | 1 |
| 4 | Synthetic pyrethroid insecticides analysis by gas chromatography/ mass spectrometry operated in negative-ion chemical ionization mode in soil, moss and fish tissue显示文摘 | Yasin M Baugh P J Hancock P | 1995 | Rapid Communications in Mass Spectrometry1995，9，： | 1 |
| 5 | Advanced Manufacturing Technology:Implementation Policy and Performance显示文摘 | Small M H Yasin M M | 1997 | Journal of Operations Management1997，15，： | 1 |
| 6 | mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis 显示文摘 | Yasin SA Ali AM Tata M et at | 2013 | Acta Neuropathol2013，126，2： | 1 |
| 7 | Microbial- enhanced selenium and iron biofortification of wheat (Triticum aetivum L ) - Applications in phyt_oremediation and biofortification 显示文摘 | Yasin M Mehdawi A F E Anwa A | 2015 | International Journal of Phytoremediation2015，17，4： | 1 |
| 8 | Advanced Manufacturing Technology:Implementation Policy and Performance显示文摘 | YASIN M M | 1997 | Journal of Operations Management1997，15，4： | 1 |
| 9 | Analytical method development for the determination of synthetic pyrethroid insecticides in soil by gas chromatographmass spectrometry operated in negative-ionization mode显示文摘 | Yasin M Baugh P J Bonwick G A | 1996 | J Chromatogr A1996，754，： | 1 |
| 10 | Techniques of EMG signal analysis: detection, processing, classification and applications显示文摘 | REAZ M B I HUSSAIN M S MOHDYASIN F | 2006 | Biological Procedures Online2006，8，1： | 1 |
| 11 | Stress history-dependent deformation characteristics of dense sand in plane strain 显示文摘 | Yasin S J M Tatsuoka F | 2000 | Soils and Foundations2000，40，2： | 1 |
| 12 | Leptin in pediatrics: a hormone from adipocyte that wheels several functions in children显示文摘 | Soliman AT Yasin M Kassem A | 2012 | Indian J Endocrinol Metab2012，16，3： | 1 |
| 13 | Anti-apoptptic and anti- inflammatory effects of hydrogen sulfide in a rat model of region- gal myocardial I/R显示文摘 | Sivarajah A Collino M Yasin M | 2009 | Shock2009，31，3： | 1 |
| 14 | An energy saving atmospheric evaporator utilizing low grade thermal or waste energy显示文摘 | Aboabboud M M Horvath L Mink G Yasin M and Kudish A I | 1996 | Energy1996，21，12： | 1 |
| 15 | Are immediate early genes involved in gonadotropin-releasing hormone receptor gene regulation? Characterization of changes in GnRH receptor (GnRH-R), c-fos, and c- jun messenger ribonucleic acids during the ovine estrous cycle 显示文摘 | Padmanabhan V Dalkin A Yasin M | 1995 | Biol Reprod1995，53，2： | 1 |
| 16 | Synthesis and characterization of linear low-density polyethylene/sepiolite nanocompos- ites 显示文摘 | Shafiq M Yasin T | 2012 | Journal of Applied Polymer Science2012，123，3： | 1 |
| 17 | Simultaneous Wave and Particle knowledge in a Neutron Interferometer显示文摘 | GREENBERGER D M YASIN A | 1988 | Phys LettA1988，128，8： | 1 |
| 18 | Stress history-dependent deformation characteristics of danse sand in plane arain显示文摘 | YASIN S J M TATSUOKA F | 2000 | Soils and Foundations2000，40，2： | 1 |
| 19 | Active vibration control of piezoelectric laminated beams with electroded actuators and sensors using an efficient finite element involving an electric node显示文摘 | KAPURIA S YASIN M Y | 2010 | Smart Materials and Structures2010，19，： | 1 |
| 20 | Inappropriate use of proton pump inhibitors among medical inpatients: a questionnaire-based observational study 显示文摘 | Haroon M Yasin F Gardezi S K | 2013 | JRSM ShortRep2013，4，20： | 1 |
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