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| 1 | Biomarkers in triple negative breast cancer:A review显示文摘Breast cancer is an intrinsically heterogeneous disease. In the world about 1 million cases of breast cancer are diagnosed annually and more than 170000 are triplenegative. Characteristic feature of triple negative breast cancer(TNBC) is that it lacks expression of oestrogen,progesterone and human epidermal growth factor receptor-2/neu receptors. They comprise 15%-20% of all breast cancers. We did a systematic review of Pub Med and conference databases to identify studies published on biomarkers in TNBC. We included studies with biomarkers including: Epidermal growth factor receptor,vascular endothelial growth factor,c-Myc,C-kit and basal cytokeratins,Poly(ADP-ribose) polymerase-1,p53,tyrosinase kinases,m-TOR,heat and shock proteins and TOP-2A in TNBC. We also looked for studies published on synthetic lethality and inhibition of angiogenesis,growth,and survival pathways. TNBC is a complex disease subtype with many subclasses. Majority TNBC have a basal-like molecular phenotype by gene expression profiling. Their clinical and pathologic features overlap with hereditary BRCA1 related breast cancers. Management of these tumours is a challenge to the clinician because of its aggressive behaviour,poor outcome,and absence of targeted therapies. As the complexity of this disease is being simplified over time new targets are also being discovered for the treatment of this disease. There are many biomarkers in TNBC being used in clinical practice. Biomarkers may be useful as prognostic or predictive indicators as well as suggest possible targets for novel therapies. Many targeted agents are being studied for treatment of TNBC. | Budhi S Yadav Priyanka Chanana Swaty Jhamb | 2015 | World Journal of Clinical Oncology2015，6，6： | 13 |
| 2 | Triple plating of tibia in a complex bicondylar tibial plateau fracture显示文摘高精力的胫骨的高原骨折为整形外科的外科医生提出重要挑战和困难。胫骨的高原的骨折包含主要重量适用连接并且可以改变膝 kinematics。近似胫骨的关节的表面,手足轴(手足排列) 的恢复和允许早联合的运动的稳定的固定的解剖重建是处理的目标。在胫骨的高原折断的复杂 bicondylar 的情况下,孤立侧面的 plating 经常与内翻足 malalignment 被联系,更好的结果通过双切口与双边的 plating 被获得了。然而,有时,胫骨的高原折断的 bicondylar 的一种复杂类型在中间的高原在哪个让 biplaner 象 sagittal 飞机一样在以后的花冠飞机断裂被遇到。在如此的破裂,与在两架飞机支持修理中间的高原是必要的。近似胫骨的一个如此的破裂模式通过双 posteromedial 由三倍的 plating 设法,在前面偏一边的切口在这类损害,外科的途径和管理的机制上与强调在这份情况报告被讨论。 | Atin Jaiswal Naiman Deepak Kachchhap Yashwant S Tanwar Birendra Kumar Sachin K Yadav | 2014 | Chinese Journal of Traumatology2014，17，3： | 10 |
| 3 | Evidence for a disease-resistance pathway in rice similar to the NPR1-mediated signaling pathway in Arabidopsis显示文摘 | Chern M S Fitzgerald H A Yadav R C | 2001 | Plant J2001，27，2： | 2 |
| 4 | Carotid stent-supported angioplasty: a neurovascular intervention to prevent stroke显示文摘 | Roubin G S Yadav S Lyer S S | 1996 | Am J Cardiol1996，78，10： | 2 |
| 5 | Interventional advances in long-term stroke prevention显示文摘 | Yadav J S | 2001 | J Stroke Cerebrovascular Disease2001，10，2： | 2 |
| 6 | Improved dielectric and electro-optical parameters of nematic liquid crystal doped with magnetic nanoparticles显示文摘This study investigates the effect of magnetic nanoparticles(NPs) on the weakly polar nematic liquid crystal(NLC).Different parameters of dielectric data were measured for both the homeotropic and planar aligned samples as a function of frequency and temperature and the substantial changes have been noticed for the doped systems. Dielectric permittivity has been increased after the dispersion of magnetic NPs in the pure NLC. Dielectric anisotropy has also been influenced by incorporating the magnetic NPs with the NLC molecules. These results were attributed to the dipole–dipole interaction between the magnetic nanoparticles and nematic liquid crystal molecules. Electro-optical study indicated the faster rise time and fall time of the doped systems as compare to pure NLC. Threshold voltage has been calculated and found to be decreased for the doped systems. Moreover, we have also calculated the rotational viscosity and the splay elastic constant for pure and the doped systems. Both the rotational viscosity and splay elastic constant of the doped systems are found to be considerably lower than those of pure NLC. Change in these properties has been explained on the basis of molecular disturbances created by the interaction between the magnetic nanoparticle and LC director. This study reveals that the inclusion of magnetic NPs in weakly polar NLC can be useful to enhance the basic properties of the weakly polar NLC and make it a promising material for many display applications. | Geeta Yadav Govind Pathak Kaushlendra Agrahari Mahendra Kumar Mohd Sajid Khan V S Chandel Rajiv Manohar | 2019 | Chinese Physics B2019，28，3： | 2 |
| 7 | Protection against radiation induced chromsome damage by Emblica of ficinalis fruit extract显示文摘 | Yadav S K | 1987 | Caryologia1987，40，3： | 1 |
| 8 | Antidiabetie effect of probiotie dalai containing Laetobaeillus aeidophilus and Laetobaeillus casei in high fructose fed rats显示文摘 | YADAV H JAIN S | 2006 | Nutrition2006，41，6： | 1 |
| 9 | Recent developments in the synthesis of prostaglandins and analogues 显示文摘 | Das S Chandrasekhar S Yadav JS | 2007 | Chem Rev2007，107，7： | 1 |
| 10 | Transgenic tobacco over- expressing glyoxalase pathway enzymes grow and set viable seeds in zinc- spiked soils显示文摘 | SINGLA P S L YADAV S K PAREEK A | 2006 | Plant Physiology2006，140，2： | 1 |
| 11 | Indium(llI) chloride/2-iodoxybenzoic acid: a novel reagent system for the conversion of indoles into isatins显示文摘 | Yadav JS Reddy B V S Reddy C h S | 2007 | Synthesis2007，5，： | 1 |
| 12 | The development of an adaptive decision support system显示文摘 | Ta-Tao Chuang Yadav S B | 1998 | Decision Support Systems1998，24，2： | 1 |
| 13 | 显示文摘 | YADAV J S REDDY B V S REDDY K B | 2002 | Tetrahedron Lett2002，43，39： | 1 |
| 14 | Prevalence&risk factors of pre-hy-pertension&hypertension in an affluent north Indian population显示文摘 | Yadav S Boddula R Genitta G | 2008 | In-dian J Med Res2008，128，6： | 1 |
| 15 | InCl3-cata-lyzed regioselective opening of aziridines with heteroaro-matics显示文摘 | Yadav J S Reddy B V S Abraham S | 2002 | Tetrahedron Lett2002，43，8： | 1 |
| 16 | Dentoskeletal and soft tis- sue effects of mini-implants in Class Ⅱ division 1 patients显示文摘 | Upadhyay M Yadav S Nagaraj K | 2009 | An- gle Orthod2009，79，2： | 1 |
| 17 | An empirical investigation of consumer satisfaction after service failure and recovery显示文摘 | McCullough M A Berry L L Yadav M S | | 0，，02： | 1 |
| 18 | Overexpression of a tea flavanone 3- hydroxylase gene confers tolerance to salt stress and Ahernaria solani in transgenic tobacco 显示文摘 | Mahajan M Yadav S K | 2014 | Plant Molecular Biology2014，85，6： | 1 |
| 19 | Purification and Characterization of α -L -rhamnosidase from Penicillium corylopholum MTCC - 2011 显示文摘 | Yadav S Yadava S Yadav K D S | 2013 | Process Biochemistry2013，48，9： | 1 |
| 20 | Hybrid connection algorithm:A strategy for efficient restoration in WDM optical networks显示文摘 | Yadav D Rana S Prakash S | 2010 | Optical Fiber Technology2010，16，2： | 1 |
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