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| 1 | Ultrasonographic Characteristics of Cortical Sulcus Development in the Human Fetus between 18 and 41 Weeks of Gestation显示文摘 | Sheng-Li Li Guo-Yang LUO Errol R Norwitz Shu-Yuan Ouyang Hua-Xuan Wen Ying Yuan Xiao-Xian Tian Jia-Min He Xi Chen | 2017 | Chinese Medical Journal2017，，8： | 15 |
| 2 | Transcriptomic landscape regulated by the 14 types of bone morphogenetic proteins(BMPs)in lineage commitment and differentiation of mesenchymal stem cells(MSCs)显示文摘Mesenchymal stem cells(MSCs)are ubiquitously-existing multipotent progenitors that can self-renew and differentiate into multiple lineages including osteocytes,chondrocytes,adipocytes,tenocytes and myocytes.MSCs represent one of the most commonly-used adult progenitors and serve as excellent progenitor cell models for investigating lineagespecific differentiation regulated by various cellular signaling pathways,such as bone morphogenetic proteins(BMPs).As members of TGFb superfamily,BMPs play diverse and important roles in development and adult tissues.At least 14 BMPs have been identified in mammals.Different BMPs exert distinct but overlapping biological functions.Through a comprehensive analysis of 14 BMPs in MSCs,we demonstrated that BMP9 is one of the most potent BMPs in inducing osteogenic differentiation of MSCs.Nonetheless,a global mechanistic view of BMP signaling in regulating the proliferation and differentiation of MSCs remains to be fully elucidated.Here,we conducted a comprehensive transcriptomic profiling in the MSCs stimulated by 14 types of BMPs.Hierarchical clustering analysis classifies 14 BMPs into three subclusters:an osteo/chondrogenic/adipogenic cluster,a tenogenic cluster,and BMP3 cluster.We also demonstrate that six BMPs(e.g.,BMP2,BMP3,BMP4,BMP7,BMP8,and BMP9)can induce ISmads effectively,while BMP2,BMP3,BMP4,BMP7,and BMP11 up-regulate Smad-independent MAP kinase pathway.Furthermore,we show that many BMPs can upregulate the expression of the signal mediators of Wnt,Notch and PI3K/AKT/mTOR pathways.While the reported transcriptomic changes need to be further validated,our expression profiling represents the first-of-its-kind to interrogate a comprehensive transcriptomic landscape regulated by the 14 types of BMPs in MSCs. | Linghuan Zhang Qing Luo Yi Shu Zongyue Zeng Bo Huang Yixiao Feng Bo Zhang Xi Wang Yan Lei Zhenyu Ye Ling Zhao Daigui Cao Lijuan Yang Xian Chen Bin Liu William Wagstaff Russell R*Reid Hue H*Luu Rex C*Haydon Michael J*Lee Jennifer Moriatis Wolf Zhou Fu Tong-Chuan He Quan Kang | 2019 | Genes & Diseases2019，6，3： | 11 |
| 3 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 4 | Systemic complement depletion diminishes perihematomal brain edema in rats显示文摘 | Xi G Hua Y Keep R F | 2001 | Stroke2001，32，1： | 2 |
| 5 | Self-evolution Neural Model 显示文摘 | Shuai J W Chen Z XI Liu R T | 1996 | Physics Letters-A1996，221，5： | 1 |
| 6 | Complement activation in the brain after esperimental intracerebral hemorrhage 显示文摘 | HUA Y XI G KEEP R F | 2000 | Neurosurg2000，92，： | 1 |
| 7 | Residual LifePredictions for Ball Bearings Based on Self-organ-izing Map and Back Propagation Neural NetworkMethods显示文摘 | Huang R Q Xi L F Li X L | 2007 | Mechanical Systems and Signal Pro-cessing2007，21，1： | 1 |
| 8 | Clinical significance of mi- crometastases detection in lymph nodes from head and neck squamous ceil carcinoma 显示文摘 | Ferris R Xi L Raja S | 2008 | Otolaryngol Head Neck Surg2008，139，3： | 1 |
| 9 | Evidence that wakefulness and REM sleep are controlled by a GABAergic pontine mechanism 显示文摘 | XI M C MORALES F R CHASE M H | 1999 | J Neurophysiol1999，82，4： | 1 |
| 10 | Climbing the walls显示文摘 | TUMMALA R L MUKHERJEE R XI N | 2002 | IEEE Robotics & Automation Magazine2002，9，4： | 1 |
| 11 | Ultrasonic pretreatment and acid hydrolysis of sugarcane bagasse for succinic acid production using Actinobacillus succinogenes显示文摘 | Xi YL Dai WY Xu R | 2013 | Bioprocess and Biosystems Engineering2013，36，11： | 1 |
| 12 | Ultra-early clot aspiration after lysis with tissue plasminogen activator in a porcine model of intracerebral hemorrhage: edema reduction and blood-brain barrier protection显示文摘 | Wagner K R Xi G Hua Y | 1999 | J Neurosurg1999，90，3： | 1 |
| 13 | Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling显示文摘 | Xi X Bodnar R J Li Z | 2003 | J Cell Biol2003，162，2： | 1 |
| 14 | Intraeerebral haemorrhage: mechanisms of in- jury and therapeutic targets显示文摘 | Keep R F Hua Y Xi G | 2012 | Lancet Neurol2012，11，8： | 1 |
| 15 | The condensin complexis essential for amitotic segregation of bulk chromosomes,but notnucleoli,in the ciliate Tetrahymena thermophila 显示文摘 | Cervantes M D Coyne R S Xi X | 2006 | Mol CellBiol2006，26，12： | 1 |
| 16 | Residual Life Predictions for Ball Bearings Based on Self-organizing Map and Back Propagation Neural Network Methods显示文摘 | Huang R Q Xi L F Li X L | 2007 | Mechanical Systems and Signal Processing2007，21，： | 1 |
| 17 | Modification of Wyoming montmorillonite surfaces using a cationic surfactant 显示文摘 | XI YUNFEI FROST R L HE HONGPING | 2005 | Langmuir2005，21，19： | 1 |
| 18 | Web service recommendation via exploiting location and QoS information显示文摘 | CHEN Xi ZHENG Zi-bin YU Qi LYU M R | 2014 | IEEE Transactions on Parallel and Distributed Systems2014，25，7： | 1 |
| 19 | Comprehensive evaluation of effects of straw-based electricity generation:A Chinese case显示文摘 | Liu H Polenske K R Xi Y | 2010 | Energy Policy2010，38，10： | 1 |
| 20 | Hydrosuction sediment removal systems (HSRS):Principles and field test显示文摘 | Hotchkiss R H Xi Huang | 1995 | Journal of Hydraulic Research1995，，6： | 1 |
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