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| 1 | 2005年全国治超工作要点显示文摘 | Issued by Ministry of Communications of the People′s Republic of China,T he Ministry of Public Security of the People′s Republic of China,National Development and Reform Comm ission,the Ministry of Propaganda of the CPC Central Committee,General Administration of Qu ality Supervision Inspection and Quarantine of the PRC,State Administration of Work Safety,State Administration for Industry & Commerce,China Legislative | 2005 | 交通标准化2005，，5： | 34 |
| 2 | Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients显示文摘AIM: To investigate the effect of omega-3 fatty acid parenteral supplementation postoperatively on clinical outcomes and immunomodulation in colorectal cancer patients. METHODS: Forty-two patients undergoing radical colorectal cancer resection with an indication for total parenteral nutrition postoperatively were enrolled in this prospective, double-blind, randomized, controlled study. Patients received total parenteral nutrition supplemented with either soybean oil (LCT; Intralipid, Fresenius-Kabi, SO group, n = 21) or a combination of omega-3 fish oil and soybean oil (LCT:fish oil = 5:1, fish oil; Omegaven, Fresenius-Kabi, FO group, n = 21), up to a total of 1.2 g lipid/kg per day for 7 d postoperatively. A same volume calorie and nitrogen was administrated. Routine blood test, biochemistry, systemic levels of IL-6 and TNF-α, percentage of CD3+, CD4+, and CD8+ lymphocytes were evaluated preoperatively and on postoperative d 1 and 8. Patient outcome was evaluated considering mortality during the hospital stay, length of postoperative hospital stay, and occurrence of infectious complications. RESULTS: Both lipid regimens were well tolerated. No differences between the two groups were noticed in demographics, baseline blood test, biochemistry, serum levels of IL-6 and TNF-α, percentage of CD4+, CD8+ lymphocytes, and ratios of CD4+/CD8+. Compared with those on postoperative d 1, serum IL-6 levels onpostoperative d 8 were significantly depressed in the FO group than in the reference group (-44.43 ± 30.53 vs -8.39 ± 69.08, P = 0.039). Simultaneously, the ratios of CD4+/CD8+ were significantly increased in the FO group (0.92 ± 0.62 vs 0.25 ± 1.22, P = 0.035). In addition, depression of serum TNF-α levels (-0.82 ± 2.71 vs 0.27 ± 1.67, P = 0.125) and elevation of CD3+ and CD4+ lymphocyte percentage (12.85 ± 11.61 vs 3.84 ± 19.62, P = 0.081, 17.80 ± 10.86 vs 9.66 ± 17.55, P = 0.084, respectively) were higher in the FO group than in the reference group. Patients in the FO group trended to need a shorter postoperative hospital stay (17.45 ± 4.80 d vs 19.62 ± 5.59 d, P = 0.19). No statistically significant difference was found when stratified to mortality and occurrence of infectious complications. CONCLUSION: Postoperative supplementation of omega-3 fatty acids may have a favorable effect on the outcomes in colorectal cancer patients undergoing radical resection by lowering the magnitude of inflammatory responses and modulating the immune response. | Bin Liang, Shan Wang, Ying-Jiang Ye, Xiao-Dong Yang, You-Li Wang, Jun Qu, Qi-Wei Xie, Mu-Jun Yin, Division of Surgical Oncology and Division of Gastroenterological Surgery, Peking University People’s Hospital, Beijing 100044, China Author contributions: Liang B and Wang S contributed equally to this work Liang B and Wang S designed the research Liang B, Ye YJ, Yang XD, Wang YL, Qu J, Xie QW, Yin MJ performed the research and collected the data Wang S and Ye YJ supervised the research Liang B and Ye YJ analyzed the data Liang B wrote the paper and revised the manuscript. | 2008 | World Journal of Gastroenterology2008，14，15： | 31 |
| 3 | Influence of whole peptidoglycan of bifidobacterium on cytotoxic effectors produced by mouse peritoneal macrophages显示文摘INTRODUCTIONBifidobacteria are physiologically beneficial bacteria which are perdominant in human intestine ,and possess the most important functions .They play an important role in maintaining microbial balance of the intestine .Furthermore , their presence is thought to be an important indication of health of the body [1-4].Whole peptidoglycan ( WPG) is the major component in the cell wall of bifidobacterium ,which is also a biological responsemodifier with nontoxic side dffcets. | Li Sheng Wang~1 Hui Ming Zhu~1 Dian Yuan Zhou~2 Yu Lin Wang~1 Wan Dai Zhang~2 ~1Departrnent of Gastroenterology,Shenzhen Municipal People’s Hospital,Jinan University of Medical Sciences,Shenzhen 518020,Guangdong Province,China ~2Chinese PLA Institute of Digestion,the First Military Medical University,Guangzhou 510515,Guangdong Province,ChinaLi Sheng Wang graduated and obtained Ph.D,from the First Military Medical University in 1998,now working at Department of Gastroenterology,Shenzhen Municipal People’s Hospital.Jinan University of Medical Sciences.having 35 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 15 |
| 4 | 西班牙结核病人的治疗完成和病死率现状显示文摘目的:确定结核病人的完成治疗情况,并分析中断治疗和病死的相关因素。方法:在 SEPAR 结核病和呼吸道感染工作组成员工作的地区,对 1999 年 6 月 1 日至2000 年5 月 31 日期间开始接受治疗的结核病人进行前瞻性队列分析。利用 logistic 回归对与中断治疗和病死相关的诸因素进行了研究,并计算各因素的比数比(OR)及其 95%CI。结果:本项研究涉及 76 家医院 142 名医生提供的1515 例病例信息。82%的病人完成了全部治疗,14%中断治疗,5%死亡,0.5%治疗失败,8.7%由于迁出或其它原因中断了治疗。与中断治疗有关的变量是静脉吸毒(IVDU)(OR=6.00,95%CI:2.59-13.89和移民(OR=8.57,95%CI:3.78-19.45);性别、年龄、无家可归、监禁、DOT或住院治疗与中断治疗无关。病人病死率的预报因素有酗酒(OR=6.38,95%CI:2.09-19.48);HIV 感染(OR=7.08,95%CI:2.08-29.15)和年龄大于 64 岁(OR=10,95%CI:2.9-34.07),性别、吸毒、无家可归、DOT 和住院治疗与病人的病死率无关。结论:在发达国家应对吸毒和移民病人采用 DOT,另外,需要对酗酒、HIV 感染、年龄大于64 岁者实施严格监督以降低其病死率。 | J.A.Caylà J.A.Caminero R.Rey N.Lara X.Vallès H.Galdós-Tangüis Working Group on Completion of Tuberculosis Treatment in Spain 姜世闻 | 2004 | 结核与肺部疾病杂志2004，7，2： | 2 |
| 5 | Gross and microscopic morphology of lesions in Cnidaria from Palmyra Atoll, Central Pacific显示文摘 | WILLIAMS G J WORK T M AEBY G S | 2011 | Journal of Invertebrate Pathology2011，106，： | 1 |
| 6 | Small-cell lung cancer:ESMO clinical recommendations for diagnosis,treatment and follow-up显示文摘 | S(o)rensen M Felip E ESMO Guidelines Working Group | 2009 | Ann Oncol2009，204，： | 1 |
| 7 | The non-Hodgkin's lymphoma pathology classification project显示文摘 | National Cancer Institute sponsored study of classifications of non-Hodgkin's lymphomas:sunnary/and description of a working formulation for clinical usage | 1982 | Cancer1982，49，： | 1 |
| 8 | Theoretical accountsand applications for scholastic development 显示文摘 | Hitch G J Towse J N Hutton Uf What limitschildren’s working memory span | 2001 | Journal of Experimental Psychology: General2001，130，4： | 1 |
| 9 | Randomized study of initial versus late chest irradiation combined with chemotherapy in limited-stage small-cell lung cancer显示文摘 | Work E Nielsen O S Bentzen S M | 1997 | J Clin Oncol1997，15，9： | 1 |
| 10 | Replicating genotype-phenotype associations 显示文摘 | NCI-NHGRI Working Group on Replication in Asso- ciation Studies CHANOCK S J MANOLIO T | 2007 | Nature2007，447，： | 1 |
| 11 | The NIH human microbiome project显示文摘 | NIH HMP Working Group Peterson J Garges S Giovanni M McInnes P Wang L Schloss JA Bonazzi V McEwen JE Wetterstrand KA Deal C Baker CC Di Francesco V Howcroft TK Karp RW Lunsford RD Wellington CR Belachew T Wright M Giblin C David H Mills M Salomon R Mullins C Akolkar B Begg L Davis C Grandison L Humble M Khalsa J Little AR Peavy H Pontzer C Portnoy M Sayre MH Starke-Reed P Zakhari S Read J Watson B Guyer M | 2009 | Genome Res2009，19，12： | 1 |
| 12 | Thermal conductivity of ultem/earbon nanofiUer blends 显示文摘 | GHOSE S WORKING D C CONNELL J W | 2006 | High Perform Polym2006，18，6： | 1 |
| 13 | Standard preanalytical coding for biospeeimens: defining the sample PREanalytieal code 显示文摘 | Betsou F Lehmann S Ashton G International Society for Biological and Environmental Repositories(ISBER) Working Group on Biospecimen Science | 2010 | Cancer Epidemiol Biomarkers Prev2010，19，： | 1 |
| 14 | The NIH human microbiome project显示文摘 | NIH HMP Working Group Peterson J Garges S | 2009 | Genome Res2009，19，12： | 1 |
| 15 | organotypic models for the assessment/prediction of ocular irritation 显示文摘 | CHAMBERLAIN M GAD 1RAG working group 1 S C GAUTHERON P | 1997 | Food Chem Toxicol1997，35，： | 1 |
| 16 | Intensive care adult patients with severe respiratory failure caused by influenza A(H1N1)v in Spain显示文摘 | Rello J Rodríguez A Ibaez P Socias L Cebrian J Marques A Guerrero J Ruiz-Santana S Marquez E Del Nogal-Saez F Alvarez-Lerma F Martínez S Ferrer M Avellanas M Granada R Maraví-Poma E Albert P SierraR Vidaur L Ortiz P Prieto del Portillo I Galván B León-Gil C H1N1SEMICYUC Working Group | 2009 | Crit Care2009，13，5： | 1 |
| 17 | Proposed guidelines for image-based intracavitary brachytherapy for cervical carcinoma:report from Image-guided Brachytherapy Working Group显示文摘 | Nag S Cardenes H Chang S Image-guided Braehytherapy Working Group | 2004 | Int J Radiat Oncol Biol Phys2004，60，： | 1 |
| 18 | Hep- atocellular carcinoma: ESMO Clinical Practice Guidelines for diag- nosis, treatment and follow- up 显示文摘 | Jelic S Sotiropoulos GC ESMO Guidelines Working Group | 2010 | Ann Oncol2010，215，： | 1 |
| 19 | Thrombosis prevention trial:randomised trial of low-intensi- ty oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemie heart disease in men at increased risk显示文摘 | The Medical Research Council's General Practice Research Frame- work | 1998 | Lancet1998，351，9098： | 1 |
| 20 | UK Receptor Group, UK NEQAS, The Scottish Breast Cancer Pathology Group, and The Receptor and Biomarker Study Group of the EORTC 显示文摘 | Leake R Barnes D Pinder S detection of steroid receptors in breast cancer: a working protocol | 2000 | J Clin Pathol2000，53，8： | 1 |
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