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| 1 | 德国屋顶花园绿化显示文摘介绍了德国屋顶花园的类型、构造、工作原理、政府的政策支持。屋顶花园是必需品,而不是奢侈品。 | 渥尔纳·皮特·库斯特 Werner Peter Kuesters | 2005 | 中国园林2005，21，4： | 83 |
| 2 | 多功能目标下的近自然森林经营作业法研究显示文摘基于海南省热带人工林近自然化改造的实例,介绍在森林生态系统多功能可持续经营目标指导下的近自然森林作业法设计的理论基础和实现技术。作业级是一个自然性质、动态特征和经营目标基本一致的经营空间类型,而立地条件和功能类型是用于界定和划分作业级的技术指标。森林发展类型是在作业级层次上应用的长期稳定的目标森林设计模式;林分抚育作业方法是在发展类型目标导向下规定本经理期内对当前林分执行具体抚育、采伐或补植(造林)等具体作业技术的模式方法;垂直结构导向的经营周期计划给出了从森林发生发展到最终利用全过程的经营规划,这些技术要素的有机组合构成多功能目标的森林作业法的基本内容。期望通过这个在'作业级'层面的近自然森林作业法实例介绍,为多功能经营目标下的新型森林作业法研究提供启发和案例。 | 陆元昌 Werner Schindele 刘宪钊 包源 雷相东 栾慎强 孟京辉 | 2011 | 西南林学院学报2011，31，4： | 64 |
| 3 | 住宅郊区化背景下门禁社区与周边邻里关系--以广州丽江花园为例显示文摘作为'破碎城市'的典型表征,西方学者对门禁社区持负面态度,然而门禁社区在不同区域的出现受制于当地的社会文化要素,并可能对当地产生不同的影响。本文试图探讨在中国特殊的社会文化背景下,门禁社区与周边社会经济地位较低邻里的联系和社会关系,并通过分析门禁社区居民的活动范围和围墙内外居民彼此间的态度和社会交往来探讨门禁社区的影响。以广州番禺南浦岛丽江花园为案例地,结合问卷调查、深度访谈和参与式观察等研究方法,研究发现:与南非、阿根廷等国家不同的是,我国门禁社区与周边邻里存在功能性互动,并未给周边邻里造成被隔离和被歧视的心理,地理空间上的临近性反而为不同阶层和不同生活背景的居民之间的相互了解、融合和沟通提供了机会和可能。 | 封丹 Werner Breitung 朱竑 | 2011 | 地理研究2011，30，1： | 34 |
| 4 | 门禁社区边界和家的构建关系研究显示文摘门禁社区作为一种全球现象引起了学界的广泛关注。当前研究中,空间、制度、经济和社会维度是学者们关注的焦点,对门禁社区的文化分析则相对薄弱。研究基于我国社会情境,从'边界'和'家'这两个不同,却又相互交织的理论视角出发,探讨围墙的意义和家的构建,对国际范围内关于门禁社区的争论提供文化的视角。采用实地调查和深度访谈方法,研究发现,'家'的构建是通过创建'边界'来实现的。门禁社区的围墙和大门不仅仅是物质性的边界,更是一种社会和文化建构,它构建了'家',同时也成为围墙内外居民争夺'家园'的象征。 | 封丹 朱竑 Werner Breitung | 2014 | 世界地理研究2014，23，3： | 29 |
| 5 | 几种药用真菌粗提物对多种人体肿瘤细胞株增殖的抑制作用显示文摘本项研究直接采用各种人体肿瘤细胞株作为供试体 ,检测了几种药用真菌粗提物在体外对不同人体肿瘤细胞增殖的抑制作用 ,建立了一套筛选抗肿瘤药物的体外检测系统。检测样品对肿瘤细胞增殖的抑制作用采用比利时 Biosource公司的 AlamarBlue Assay试剂盒。本项研究检测了云芝、灵芝、猴头和灰树花四种药用真菌的粗提物( YZ、LZ、HT和 HSH)对五种人体肿瘤细胞株 :慢性骨髓性白血病细胞株 ( K562 )、大肠腺癌细胞株 ( SW62 0 )、乳腺腺癌细胞株 ( MCF7)、急性 T淋巴白血病细胞株 ( Jurkat)和大肠腺癌细胞株 ( L S180 )增殖的抑制作用。结果显示 ,四种药用真菌粗提物对 K562、SW62 0和 Jurkat的增殖都有不同程度的抑制作用。相比之下 ,YZ对 K562和 SW62 0的抑制作用最强。而 HT对 Jurkat的抑制作用最强 ,只有 YZ和 L Z对 L S180的增殖有明显的抑制作用。L Z在高浓度下不仅对 K562、SW62 0和 Jurkat,而且对 L S180的增殖抑制作用显著。四种药用真菌粗提物对 MCF7都没有明显的抑制作用。本项研究表明 ,不同的药用真菌粗提物对不同的肿瘤细胞株的增殖有不同的抑制作用 ,显示出抗肿瘤真菌具有一定的专效性。这对有目的地进行新的抗肿瘤药物的筛选和进一步在分子水平上研究抗肿瘤真菌的药理具有重要的意义。 | 张劲松 樊华 李玉详 潘迎杰 Werner Reutter | 2000 | 天然产物研究与开发2000，12，2： | 25 |
| 6 | On the combined effect of soil fertility and topography on tree growth in subtropical forest ecosystems—a study from SE China显示文摘Aims The aim of our research was to understand small-scale effects of topography and soil fertility on tree growth in a forest biodiversity and ecosystem functioning(BEF)experiment in subtropical SE China.Methods Geomorphometric terrain analyses were carried out at a spatial resolution of 5×5 m.Soil samples of different depth increments and data on tree height were collected from a total of 566 plots(667 m2 each).The soils were analyzed for carbon(soil organic carbon[SOC]),nitrogen,acidity,cation exchange capacity(CEC),exchangeable cations and base saturation as soil fertility attributes.All plots were classified into geomorphological units.Analyses of variance and linear regressions were applied to all terrain,soil fertility and tree growth attributes.Important Findings In general,young and shallow soils and relatively small differences in stable soil properties suggest that soil erosion has truncated the soils to a large extent over the whole area of the experiment.This explains the concurrently increasing CEC and SOC stocks downslope,in hollows and in valleys.However,colluvial,carbon-rich sediments are missing widely due to the convexity of the footslopes caused by uplift and removal of eroded sediments by adjacent waterways.The results showed that soil fertility is mainly influenced by topography.Monte-Carlo flow accumulation(MCCA),curvature,slope and aspect significantly affected soil fertility.Furthermore,soil fertility was affected by the different geomorphological positions on the experimental sites with ridge and spur positions showing lower exchangeable base cation contents,especially potassium(K),due to leaching.This geomorphological effect of soil fertility is most pronounced in the topsoil and decreases when considering the subsoil down to 50 cm depth.Few soil fertility attributes affect tree height after 1-2 years of growth,among which C stocks proved to be most important while pH_(KCl)and CEC only played minor roles.Nevertheless,soil acidity and a high proportion of Al on the exchange complex affected tree height even after only 1-2 years growth.Hence,our study showed that forest nutrition is coupled to a recycling of litter nutrients,and does not only depend on subsequent supply of nutrients from the mineral soil.Besides soil fertility,topography affected tree height.We found that especially MCCA as indicator of water availability affected tree growth at small-scale,as well as aspect.Overall,our synthesis on the interrelation between fertility,topography and tree growth in a subtropical forest ecosystem in SE China showed that topographic heterogeneity lead to ecological gradients across geomorphological positions.In this respect,small-scale soil-plant interactions in a young forest can serve as a driver for the future development of vegetation and biodiversity control on soil fertility.In addition,it shows that terrain attributes should be accounted for in ecological research. | Thomas Scholten Philipp Goebes Peter Kühn Steffen Seitz Thorsten Assmann Jürgen Bauhus Helge Bruelheide Francois Buscot Alexandra Erfmeier Markus Fischer Werner Härdtle Jin-Sheng He Keping Ma Pascal A.Niklaus Michael Scherer-Lorenzen Bernhard Schmid Xuezheng Shi Zhengshan Song Goddert von Oheimb Christian Wirth Tesfaye Wubet Karsten Schmidt | 2017 | Journal of Plant Ecology2017，10，1： | 22 |
| 7 | Crown and leaf traits as predictors of subtropical tree sapling growth rates显示文摘Aims Growth rates of plants are driven by factors that influence the amount of resources captured and the efficiency of resource use.In trees,the amount of light captured and the efficiency of light use strongly depends on crown characteristics and leaf traits.Although theory predicts that both crown and leaf traits affect tree growth,few studies have yet to integrate these two types of traits to explain species-specific growth rates.Using 37 broad-leaved tree species of subtropical forests in SE China,we investigated how interspecific differences in wood volume growth rates were affected by crown and leaf traits.We tested the hypotheses that(i)larger crown dimensions promote growth rates,(ii)species-specific growth rates are positively related to leaf stomatal conductance,leaf water potential and leaf chemical components,and negatively related to leaf C/N and leaf toughness and(iii)the two sets of traits better explain growth rates in combination than either alone.Methods Our study was conducted in a large-scale forest Biodiversity and Ecosystem Functioning experiment in China(BEF-China),located in a mountainous region in Jiangxi Province.We related 17 functional traits(two crown dimension and three crown structure traits;six physiological and six morphological leaf traits)to the mean annual growth rate of wood volume of young trees of the studied species.Interrelationships between crown and leaf traits were analyzed using principal component analysis.Simple linear regression analysis was used to test the effect of each trait separately.We used multiple regression analysis to establish the relationship of growth rate to each set of traits(crown traits,physiological and morphological leaf traits)and to the combination of all types of traits.The coefficients of determination(R^(2)_(adj))of the best multiple regression models were compared to determine the relative explanatory power of crown and leaf traits and a combination of both.Important Findings The species-specific growth rates were not related to any of the single crown traits,but were related positively to leaf stomatal conductance and leaf water potential individually,and negatively to leaf toughness,with approximately 13%variance explained by each of the traits.Combinations of different crown traits did not significantly explain the species-specific growth rates,whereas combinations of either physiological or morphological leaf traits explained 24%and 31%,respectively.A combination of both crown and leaf traits explained 42%of variance in species-specific growth rates.We concluded that sets of traits related to carbon assimilation at the leaf-level and to overall amount of leaves exposed at the crown-level jointly explained species-specific growth rates better than either set of traits alone. | Ying Li Wenzel Kröber Helge Bruelheide Werner Härdtle Goddert von Oheimb | 2017 | Journal of Plant Ecology2017，10，1： | 18 |
| 8 | Interspecific and intraspecific variation in specific root length drives aboveground biodiversity effects in young experimental forest stands显示文摘Aims Although the net biodiversity effect(NE)can be statistically partitioned into complementarity and selection effects(CE and SE),there are different underlying mechanisms that can cause a certain partitioning.Our objective was to assess the role of resource partitioning and species interactions as two important mechanisms that can bring about CEs by interspecific and intraspecific trait variation.Methods We measured tree height of 2493 living individuals in 57 plots and specific root length(SRL)on first-order roots of 368 of these individuals across different species richness levels(1,2,4,8 species)in a large-scale forest biodiversity and ecosystem functioning experiment in subtropical China(BEF-China)established in 2009.We describe the effects of resource partitioning between species by a fixed component of interspecific functional diversity(RaoQ)and further effects of species interactions by variable components of interspecific and intraspecific functional diversity(community weighted trait similarity and trait dissimilarity,CWS and CWD).Finally,we examined the relationships between biodiversity effects on stand-level tree height and functional diversity(RaoQ,CWS and CWD)in SRL using linear regression and assessed the relative importance of these three components of functional diversity in explaining the diversity effects.Important Findings Our results show that species richness significantly affected SRL in five and tree height in ten out of 16 species.A positive NE was generally brought about by a positive CE on stand-level tree height and related to high values of RaoQ and CWS in SRL.A positive CE was related to high values of all three components of root functional diversity(RaoQ,CWS and CWD).Our study suggests that both resource partitioning and species interactions are the underlying mechanisms of biodiversity effects on stand-level tree growth in subtropical forest. | Wensheng Bu Bernhard Schmid Xiaojuan Liu Ying Li Werner Härdtle Goddert von Oheimb Yu Liang Zhenkai Sun Yuanyuan Huang Helge Bruelheide Keping Ma | 2017 | Journal of Plant Ecology2017，10，1： | 18 |
| 9 | 西藏班公湖—怒江缝合带白垩系沉积特征及其构造意义显示文摘班公湖—怒江位于西藏中部 ,西起班公湖日土 (33.5°N ,79°E) ,向东经由措勤、尼玛、那曲至东部怒江带 ,走向近东西、其中部大致平行于北纬 32°线 ,延长大于 15 0 0km。该带蛇绿岩发育 ,是中生代板块缝合线 ,是南部拉萨地块与北部羌塘地块的分界线。其中段班戈地区白垩系地层发育 ,包括下白垩统底部川巴组 (K1c)、多巴组 (K1d)、郎山组 (K1l)和上白垩统江巴组 (K2 j)。川巴组为浅海相黑色页岩、泥岩、粉砂岩、砂岩、煤层和火山岩 ;多巴组为含有海侵夹层的陆相碎屑岩建造 ,海侵层为含园笠虫 (Orbitolinasp .)钙质砂岩 ;郎山组为浅海相—泻湖相台地型碳酸盐岩沉积 ;江巴组以陆相、厚层块状的砂砾岩红层为特征。本区白垩系层序的总体特征 ,是以海相火山岩—细碎屑岩为先导、经海陆过渡相碎屑岩和海相碳酸盐岩到陆相红层 ,形成于与B型俯冲作用有关的活动大陆边缘构造背景. | 王璞珺 Frank Mattern Werner Schneider 刘万洙 田纹全 李才 | 2003 | 世界地质2003，22，2： | 18 |
| 10 | Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial显示文摘AIM: To investigate efficacy and safety of cetuximab combined with two chemotherapy regimens in patients with unresectable metastatic colorectal cancer (mCRC). METHODS: Randomized patients received cetuximab with 5-fluorouracil (5-FU), folinic acid (FA) and oxaliplatin (FOLFOX) 6 (arm A, n = 74) or 5-FU, FA and irinotecan (FOLFIRI) (arm B, n = 77). KRAS mutation status was determined retrospectively in a subset of tumors (n = 117). RESULTS: No significant difference was found between treatment arms A and B in the progression-free survival (PFS) rate at 9 mo, 45% vs 34%; median PFS, 8.6 mo vs 8.3 mo [hazard ratio (HR) = 1.06]; overall response rate (ORR) 43% vs 45% [odds ratio (OR) = 0.93] and median overall survival (OS), 17.4 mo vs 18.9 mo (HR = 0.98). Patients with KRAS wild-type tumors demonstrated improved PFS (HR = 0.55, P = 0.0051), OS, (HR = 0.62, P = 0.0296) and ORR (53% vs 36%) and in arm A, improved PFS (HR = 0.49, P = 0.0196), OS (HR = 0.48, P = 0.0201) and ORR (56%vs 30%), compared with patients with KRAS mutated tumors. In arm B no significant differences were found in efficacy by KRAS mutation status. Treatment in arms A and B was generally well tolerated. CONCLUSION: This study confirms that combinations of cetuximab with FOLFOX6 or FOLFIRI are effective and significantly improve clinical outcome in KRAS wild-type compared with KRAS mutated mCRC. | Janja Ocvirk Thomas Brodowicz Fritz Wrba Tudor E Ciuleanu Galina Kurteva Semir Beslija Ivan Koza Zsuzsanna Pápai Diethelm Messinger Ugur Yilmaz Zsolt Faluhelyi Suayib Yalcin Demetris Papamichael Miklós Wenczl Zrinka Mrsic-Krmpotic Einat Shacham-Shmueli Damir Vrbanec Regina Esser Werner Scheithauer Christoph C Zie-linski | 2010 | World Journal of Gastroenterology2010，16，25： | 17 |
| 11 | Value of three-dimensional reconstructions in pancreatic carcinoma using multidetector CT:Initial results显示文摘AIM:To evaluate the use of three-dimensional imaging of pancreatic carcinoma using multidetector computed tomography(CT)in a prospective study.METHODS:Ten patients with suspected pancreatic tumors were examined prospectively using multidetec-tor CT(Somatom Sensation 16,Siemens,Erlangen,Germany).The images were evaluated for the pres-ence of a pancreatic carcinoma and invasion of the peripancreatic vessels and surrounding organs.Using the isotropic CT data sets,a three-dimensional image was created with automatic vascular analysis and semi-automatic segmentation of the organs and pancreatic tumor by a radiologist.The CT examinations and the three-dimensional images were presented to the sur-geon directly before and during the patient's operation using the Medical Imaging Interaction Toolkit-based software 'ReLiver'.Immediately after surgery,the value of the two images was judged by the surgeon.The operation and the histological results served as the gold standard.RESULTS:Nine patients had a pancreatic carcinoma(all pT3),and one patient had a serous cystadenoma.One tumor inf iltrated the superior mesenteric vein.The inf iltration was correctly evaluated.All carcinomas were resectable.In comparison to the CT image with axial and coronal reconstructions,the three-dimensional image was judged by the surgeons as better for operation planning and consistently described as useful.CONCLUSION:A 3D-image of the pancreas repre-sents an invaluable aid to the surgeon.However,the 3D-software must be further developed in order to be integrated into daily clinical routine. | Miriam Klauβ Max Schbinger Ivo Wolf Jens Werner Hans-Peter Meinzer Hans-Ulrich Kauczor Lars Grenacher | 2009 | World Journal of Gastroenterology2009，15，46： | 16 |
| 12 | 多重聚合酶链反应检测环境中产气荚膜杆菌显示文摘产气荚膜杆菌根据产生 4种主要毒素 (α、β、ε、ι 毒素 )可分为 5种类型A E型。在该研究中依据产气荚膜杆菌的 5种毒素基因的序列 ,设计了 5对PCR引物 ,建立了多重PCR方法 ,该方法可以快速区分 5种类型的产气荚膜杆菌。并对 68份环境样品 (生活污水、生物肥料 )进行检测和基因分型 ,共检出 55株产气荚膜杆菌 ,其中A型产气荚膜杆菌 50株 ,占总数的 90 %以上 ,B型、C型、D型只占 5 % ,未检出E型产气荚膜杆菌 ,所有的分离株没有发现带有肠毒素。结果表明 ,目前环境中主要存在的菌型为A型菌 ,其他菌型的产气荚膜杆菌很少 。 | 文其乙 刘秀梵 Werner Phillip Reinhard Boehm | 2002 | 畜牧兽医学报2002，33，6： | 14 |
| 13 | 回顾性分析中对计算机化压力-流率测定数据的质量控制及其效果显示文摘目的 在回顾性分析中对计算机化的压力 流率测定数据进行质量控制 ,比较质控前后数据以说明各种赝像对结果分析的影响 ,阐明回顾性质量控制的必要性。 方法 对 5 82条计算机制作的压力 流率曲线进行人工抹平更正 ,并读出最大尿流率 (Qmax)及其对应的逼尿肌压力(Pdet.Qmax) ,应用梗阻系数 (OCO)检测尿道阻力、国际尿控协会 (ICS)列线图分类和诊断梗阻、Sch fer列线图对梗阻进行分级。人工阅读结果与计算机读取结果进行统计学比较。 结果 人工更正后Qmax呈现一致性降低 (P <0 .0 0 1) ,平均降低 1.17ml/s,83.1%曲线的人工阅读值Qmax降低范围在 0 .1~ 1.9ml/s;Pdet.Qmax呈非显著性下降 (P >0 .0 5 ) ,平均降低 0 .75cmH2 O(1cmH2 O =0 .0 98kPa) ;OCO呈显著性增高 (P <0 .0 5 ) ,平均增高 0 .0 6 7。人工更正后 ,梗阻分布与程度出现显著性差别 ,ICS列线图梗阻百分数由 6 9.8%增至 73.9% (P <0 .0 5 ) ,非梗阻由 8.8%降至 5 .3% (P <0 .0 5 ) ;Sch fer列线图梗阻百分数由 72 .5 %增至 77.3% (P <0 .0 1) ,非梗阻由 9.1%降至 5 .5 % (P <0 .0 1)。使用ICS列线图及Sch fer列线图 ,人工更正后分别有 11.0 %和 2 8.9%的曲线改变了在列线图中的分类或分级 ;分别有 6 .9%及 7.2 | 廖利民 Werner Schfer | 2002 | 中华泌尿外科杂志2002，23，5： | 13 |
| 14 | High precision magnetometer for geomagnetic exploration onboard of the China Seismo-Electromagnetic Satellite显示文摘The China Seismo-Electromagnetic Satellite(CSES) is the first platform of China's earthquake observation system in space and the first satellite of China's geophysical field detection missions. The high precision magnetometer(HPM), which contains two fluxgate sensors and a coupled dark state magnetometer(CDSM), measures the vector of the Earth's magnetic field with a bandwidth from DC to 15 Hz. The two fluxgate sensors are in a gradiometer configuration in order to reduce satellite interferences. Additionally, the CDSM sensor measures the scalar value of the magnetic field with higher accuracy and stability.Several data processing and calibration methods have been prepared to get accurate vector magnetic field data. This includes the calibration of each of the three sensors, the absolute vector correction algorithm, the spacecraft magnetic interference elimination and the coordinate transformation method. Also the instrument performances based on ground calibration activities are shown in this article. | CHENG BingJun ZHOU Bin MAGNES Werner LAMMEGGER Roland POLLINGER Andreas | 2018 | Science China(Technological Sciences)2018，61，5： | 13 |
| 15 | 抑郁症的中医治疗显示文摘目的 :观察中药舒郁散治疗抑郁症的疗效及安全性 ,并与西药帕罗西汀进行对比研究。方法 :采用美国 1994年心理精神病学会的抑郁症诊断标准 ,对确诊为抑郁症的患者采用汉密尔顿抑郁量表 (HAMD) ,积分≥ 17分 ,临床表现综合评分 (CGI S)≥ 4 0的 6 5例患者纳入临床观察 ,随机分为中药舒郁散治疗组及西药帕罗西汀治疗组进行对比研究 ,观察治疗前后的汉密尔顿抑郁量表 ,临床表现综合评分 (CGI S)的积分变化来评定疗效 ;同时观察两组治疗后患者临床不良反应的发生率 ,以评定两种药物治疗的安全性。结果 :两组治疗前、后的自身积分变化比较差异有显著性意义 ,中医治疗组的有效率为 6 8 75 % ,西医治疗组的有效率为 78 78% ,两组间有效率的比较差异无显著性意义 ,西医治疗组有 36 4 %的患者出现副作用 ,中医治疗组有 12 5 %的患者出现副作用 ,两组间不良反应发生率的比较差异有显著性意义。结论 :舒郁散治疗抑郁症有效 ,虽然帕罗西汀比中药舒郁散治疗抑郁症有效率高 ,两组间统计差异无显著性意义 。 | 陈利平 张雷 Herbert Werner Ali Soltanzade | 2003 | 军医进修学院学报2003，24，2： | 13 |
| 16 | 几种药用真菌粗提物免疫调节和肿瘤抑制作用的筛选显示文摘运用高通量筛选技术检测了几种药用真菌粗提物对人体肿瘤细胞增殖的抑制作用和对小鼠巨噬细胞的激活作用,并与粗提物透析袋外的小分子成分的活性进行比较。结果显示,灵芝、猴头、云芝和灰树花粗提物对人肠腺癌细胞株SW620有很明显的抑制作用,并有显著激活小鼠巨噬细胞的作用。粗提物经过透析后,透析袋外的小分子成分对SW620的抑制作用与粗提物相似,但对小鼠巨噬细胞没有明显的激活作用。本研究所采用的高通量筛选技术为进一步筛选药用真菌的有效成分奠定了基础。 | 唐庆九 张劲松 潘迎捷 Werner Reutter 樊华 | 2003 | 食用菌学报2003，10，3： | 12 |
| 17 | 针灸并用舒郁散治疗抑郁症的效果分析显示文摘目的:观察针灸及中药舒郁散治疗抑郁症的疗效及安全性,并与西药帕罗西汀进行对比研究。方法:采用美国1994年心理精神病学会抑郁症的诊断标准,将确诊为抑郁症的患者采用汉密顿抑郁量表(Hamiltonratingscalefordepression,HAMD)积分≥17分,临床表现的综合评分(clinicalglobalimpres-sions-severityofillnessscale,CGI-S)≥4.0分的70例患者随机分为中医治疗组43例(采用针灸及中药舒郁散治疗)及西药治疗组35例(口服帕罗西汀治疗),观察治疗前后两组的HAMD,CGI-S的积分变化;同时观察治疗后两组患者临床不良反应的发生率。结果:两组治疗前HAMD评分分别为(20.4±7.2)、(21.2±6.8)、治疗后分别为(9.6±5.8)、(8.9±6.2)。治疗前后自身比较(t=7.5704,7.7939,P<0.01)。两组治疗前CGI-S评分分别为(4.2±0.8)、(4.4±0.7)、治疗后分别为(1.9±1.2)、(1.8±1.4)。治疗前后自身比较(t=10.3352,9.6857,P<0.05)。中医组治疗抑郁症的有效率为4.29%(27/42),西医组的有效率为73.53%(25/34),两组有效率比较(χ2=0.7431,P>0.05),西医治疗组38.2%(13/34)的患者出现不良反应,中医治疗组11.9%(5/42)的患者出现不良反应,两组不良反应发生率比较(χ2=7.2071,P<0.01)。结论:针灸及中药舒郁散治疗抑郁症疗效与西药帕罗西汀相同,且更? | 陈利平 王发渭 Herbert Werner | 2004 | 中国临床康复2004，8，21： | 12 |
| 18 | Transforming growth factor-β1 induces intestinal myofibroblast differentiation and modulates their migration显示文摘AIM:To investigate the effects of transforming growth factorβ1(TGF-β1)on the differentiation of colonic lamina propria fibroblasts(CLPF)into myofibroblasts in vitro. METHODS:Primary CLPF cultures were incubated with TGF-β1 and analyzed for production ofα-smooth muscle actin(α-SMA),fibronectin(FN)and FN isoforms.Migration assays were performed in a modified 48-well Boyden chamber.Levels of total and phosphorylated focal adhesion kinase(FAK)in CLPF were analyzed after induction of migration.RESULTS:Incubation of CLPF with TGF-β1 for 2 d did not changeα-SMA levels,while TGF-β1 treatment for 6 d significantly increasedα-SMA production. Short term incubation(6 h)with TGF-β1 enhanced CLPF migration,while long term treatment(6 d)of CLPF with TGF-β1 reduced migration to 15%-37% compared to untreated cells.FN and FN isoform mRNA expression were increased after short term incubation with TGF-β1(2 d)in contrast to long term incubation with TGF-β1 for 6 d.After induction of migration, TGF-β1-preincubated CLPF showed higher amounts of FN and its isoforms and lower levels of total and phosphorylated FAK than untreated cells. CONCLUSION:Long term incubation of CLPF with TGF-β1 induced differentiation into myofibroblasts with enhancedα-SMA,reduced migratory potential and FAK phosphorylation,and increased FN production.In contrast,short term contact(6 h)of fibroblasts with TGF-β1 induced a dose-dependent increase of cell migration and FAK phosphorylation without induction ofα-SMA production. | Julia Brenmoehl Sandra Nicole Miller Claudia Hofmann Daniela Vogl Werner Falk Jrgen Schlmerich Gerhard Rogler | 2009 | World Journal of Gastroenterology2009，15，12： | 12 |
| 19 | Transgenerational Inheritance and Resetting of Stress, Induced Loss of Epigenetic Gene Silencing in Arabidopsis显示文摘作为无柄的有机体,植物需要察觉到并且适应异构的环境并且由改变他们的细胞的生理学,基因规定,和染色体稳定性开发了复杂回答。最近的工作在被建议具有 epigenetic 自然的 plantsa 现象在染色体稳定性的控制上表明了可继承的压力效果。这里,我们证明温度和 UV-B 应力在 Arabidopsis 在沉默记者基因的 epigenetic 控制引起立即、可继承的变化。基因 silencing 的这个调停压力的版本在 histone 占有并且在 histone H3 acetylation 与显著改变相关但是没在 DNA methylation 包含调整。我们在记者基因 silencing 上观察了压力效果的传播到非强调的子孙,但是这效果被限制为由房间的一个小数字组成的区域并且限制了到一些非强调的子孙代。而且,基因 silencing 的导致压力的版本在种子老化期间被反对并且重设。这现象的短暂性质加亮工厂的能力限制 epigenetic 控制机制的导致压力的松驰,它多半贡献保卫染色体完整。 | Christina Lang-Mladek Olga Popova Kathrin Kiok Marc Berlinger Branislava Rakic Werner Aufsatz Claudia Jonak Marie-Theres Hauser Christian Luschnig | 2010 | Molecular Plant2010，3，3： | 11 |
| 20 | 边界融合理论视角下的同城化研究——以广佛为例显示文摘同城化融合发展是实现区域协调发展战略的重要支撑和突破口。广佛同城化作为粤港澳大湾区发展战略的重要引领和举措,仍然面临诸多的问题与挑战。以边界融合理论为视角,选取广佛重点融合地区金沙洲为案例,从市场力量与联系流、不同层级政府治理、社会团体影响以及边界社区的独特文化四个维度进行研究。研究发现:在联系流方面,广佛边界区域居民存在很强的跨界往来行为,其主要的活动目的为休闲娱乐、购物和工作,但是广佛边界在医保就医、交通出行、子女教育和购房资格等方面仍然有很强的障碍效应。在政府治理方面,同城化基层治理机制尚未构建,镇街政府间的行政壁垒严重,其同城化作用薄弱。在文化层面上,边界区域居民一定程度上产生了'广佛人'的文化身份认同,即认同自己既是广州人又是佛山人,但不同户籍人口的认同存在差异。在社会团体力量方面,产业协会和镇街商会的同城化作用有待加强。研究有利于加深我们对跨界区域协调发展的认识,能为我国其他地区的同城化发展提供借鉴与参考。 | 廖开怀 符蓝 Breitung Werner 蔡云楠 谭肖红 | 2021 | 城市发展研究2021，28，7： | 11 |
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