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| 1 | Information processing in microtubules 显示文摘 | Hameroff S R Watt R C | 1982 | J Theor Biol1982，98，： | 2 |
| 2 | Origin and therapy for hypertriglyceridaemia in type 2 diabetes显示文摘Hypertriglyceridaemia(HTG) is a risk factor for cardiovascular disease(CVD) in type 2 diabetes and is caused by the interaction of genes and non-genetic factors, specifically poor glycaemic control and obesity. In spite of statin treatment, residual risk of CVD remains high in type 2 diabetes, and this may relate to HTG and atherogenic dyslipidemia. Treatment of HTG emphasises correcting secondary factors and adverse lifestyles, in particular, diet and exercise. Pharmacotherapy is also required in most type 2 diabetic patients. Statins are the first-line therapy to achieve recommended therapeutic targets of plasma low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol. Fibrates, ezetimibe and n-3 fatty acids are adjunctive treatment options for residual and persistent HTG. Evidence for the use of niacin has been challenged by non-significant CVD outcomes in two recent large clinical trials. Further investigation is required to clarify the use of incretin-based therapies for HTG in type 2 diabetes. Extreme HTG, with risk of pancreatitis, may require insulin infusion therapy or apheresis.New therapies targeting HTG in diabetes need to be tested in clinical endpoint trials. The purpose of this review is to examine the current evidence and provide practical guidance on the management of HTG in type 2 diabetes. | Jing Pang Dick C Chan Gerald F Watts | 2014 | World Journal of Diabetes2014，5，2： | 2 |
| 3 | Improved reflectometry facility at the national institute of standards and technology显示文摘 | TARRIO C WATTS R N LUCATORTO T B | 1994 | SPIE1994，2011，： | 2 |
| 4 | Reduced striatal volumes in Parkinson’s disease:a magnetic resonance imaging study显示文摘Background:The presence and extent of structural changes in the brain as a consequence of Parkinson’s disease(PD)is still poorly understood.Methods:High-resolution 3-tesla T1-weighted structural magnetic resonance images in sixty-five PD and 27 age-matched healthy control participants were examined.Putamen,caudate,and intracranial volumes were manually traced in the axial plane of 3D reconstructed images.Striatal nuclei volumes were normalized to intracranial volume for statistical comparison.Disease status was assessed using the Unified Parkinson’s Disease Rating Scale and Hoehn and Yahr scale.Cognitive status was assessed using global status tests and detailed neuropsychological testing.Results:Both caudate and putamen volumes were smaller in PD brains compared to controls after adjusting for age and gender.Caudate volumes were reduced by 11%(p=0.001)and putamen volumes by 8.1%(p=0.025).PD striatal volumes were not found to be significantly correlated with cognitive or motor decline.Conclusion:Small,but significant reductions in the volume of both the caudate and putamen occur in PD brains.These reductions are independent of the effects of age and gender,however the relation of these reductions to the functional loss of dopamine,which is characteristic of PD,remains unclear. | Toni L Pitcher Tracy R Melzer Michael R MacAskill Charlotte F Graham Leslie Livingston Ross J Keenan Richard Watts John C Dalrymple-Alford Tim J Anderson | 2012 | Translational Neurodegeneration2012，1，1： | 2 |
| 5 | Capture and processing of exogenous antigens for presentation on MHC molecules显示文摘 | WATTS C | | 0，，： | 2 |
| 6 | Growing Multihydroxyl Hyperbranched Polymers on the Surfaces of Carbon Nanotubes by in Situ Ring-Opening Polymerization显示文摘 | Xu Y Y Gao C Watts P C P | 2004 | Macromolecules2004，37，： | 1 |
| 7 | Trends in imprint lithography for biological applications显示文摘 | Truskett V N Michael P C Watts | 2008 | Trends in Biotechnology2008，24，7： | 1 |
| 8 | Vltratructural evidence of axonal shearing as a result of lateral acceleration of the head in non - human primates显示文摘 | Maxwell WL Watt C Graham DI | 1993 | Acta Neuropathol1993，86，2： | 1 |
| 9 | Behaviors of embedded carbon nanotubes during film cracking显示文摘 | Watts P C P Hsu W K | 2003 | Nanotechnology2003，14，5： | 1 |
| 10 | Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism 显示文摘 | Chan D C Watts G F Ng T W | 2005 | Clin Chem2005，51，： | 1 |
| 11 | Laser imprint reduction using a low density foam buffer as a thermal smoothing layer at 351 nm wavelength显示文摘 | Watt R G Duke J Fontes C J | 1998 | Phys Redo Lett1998，81，21： | 1 |
| 12 | Activities of three digestive enzymes during development in the crayfish Procambarus clarkii (Decapoda) 显示文摘 | Hammer H S Bishop C D Watts S A | 2000 | J Crustac Biol2000，20，： | 1 |
| 13 | Linking purchasing to corporate competitive strategy显示文摘 | Kim K Y Hahn C K | 1992 | International Journal of Purchasing and Materials Management1992，18，4： | 1 |
| 14 | Behaviours of embedded carbon nanotubes during film cracking显示文摘 | Hsu W K | 2003 | Nanotechnology2003，，5： | 1 |
| 15 | Alow resistance boron-doped carbon nanotube-polystyrene composite显示文摘 | Paul C P Watts Wen Kuang Hsu George Z Chen | 2001 | J Mater Chem2001，11，： | 1 |
| 16 | The Aldol Reaction of Silyl Enol Ethers within a Micro Reactor显示文摘 | Wiles C Watts P Haswell S J | 2001 | Lab Chip2001，1，2： | 1 |
| 17 | Isolation and partial characterisation of immunoglobulin from southern bluefin tuna Thunnus maccoyii Castelnau显示文摘 | Watts M Munday B L Burke C M | | 0，，06： | 1 |
| 18 | Mafic dikes displacing Witwatersrand gold reefs: evidence against metamorphic-hy drothermal ore formation显示文摘 | Meier D L Heinrich C A Watts M A | 2009 | Geology2009，37，7： | 1 |
| 19 | Degradation of perchloroethylene by Fenton's reagent: speciation and pathway显示文摘 | LEUNG S W WATTS R J MILLER G C | 1992 | J Environtal Quality1992，21，： | 1 |
| 20 | Treatment of unstable distal radial fraetures with the volar loeking plating system 显示文摘 | Chung K C Watt A J Kotsis S V | 2006 | J Bone Joint Surg Am2006，88，12： | 1 |
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