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| 1 | Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization显示文摘最近的 epigenomic 研究在人的染色体预言了几千潜在的 enhancers。然而,没有为这些潜在的 enhancers 的目标倡导者的系统的描述。为活跃 enhancers 把 H3K4me2 用作一个标记,我们在人的 CD4 + T 房间识别了染色体宽的 EP 相互作用。在 6 520 个长途的染色质相互作用之中,我们识别 2 067 enhancers 与 1 619 个倡导者一起交往并且提高他们的表示。这些 enhancers 在可存取的染色质区域存在并且与各种各样的 histone 修正和聚合酶 II 绑定被联系。没有交往的 enhancers,有交往的 enhancers 的倡导者比那些在高水平被表示,并且他们的表示层次断然与交往的 enhancers 的数字被相关。有趣地,交往倡导者们以一种织物特定的方式被共同表示。我们也发现染色体被组织成交往的领域的多重层次。我们的结果定义 EP 相互作用的一个全球看法并且提供一个数据集合进一步理解 enhancer 指向和远程的染色质组织的机制。为未加工、分析的染色质相互作用数据的基因表示选集就职数字是 GSE32677。 | Iourl Chepelev Gang Wei Dara Wangsa Qingsong Tang Keji Zhao | 2012 | Cell Research2012，22，3： | 6 |
| 2 | Thestudiesontheprinciplesofstressresistancetechniquesofwin-terwheatcultivation.I.Theeffectofbreakingploughpanontherootgrowthandthestressresistanceinwheatplant[J]显示文摘 | WangSA(王树安) LiuXH(刘兴海) JinLs(金连胜) | 1986 | 华北农学报1986，1，2： | 1 |
| 3 | Cellular exposure to muscle relaxants and propofol could lead to genomic instabilityin vitro显示文摘Anesthesia is widely used in several medical settings and accepted as safe.However,there is some evidence that anesthetic agents can induce genomic changes leading to neural degeneration or apoptosis.Although chromosomal changes have not been observed in vivo,this is most likely due to DNA repair mechanisms,apoptosis,or cellular senescence.Potential chromosomal alterations after exposure to common anesthetic agents may be relevant in patients with genomic instability syndromes or with aggressive treatment of malignancies.In this study,the P388 murine B cells were cultured in vitro,and spectral karyotyping (SKY) was utilized to uncover genomewide changes.Clinically relevant doses of cisatracurium and propofol increased structural and numerical chromosomal instability.These results may be relevant in patients with underlying chromosomal instability syndromes or concurrently being exposed to chemotherapeutic agents.Future studies may include utilization of stimulated peripheral blood lymphocytes to further confirm the significance of these results. | Allen Edward Coleman Nicole McNeil Alexander Leonidovich Kovalchuck Dara Wangsa Thomas Ried Hong Wang | 2012 | The Journal of Biomedical Research2012，26，2： | 1 |
| 4 | Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal Pap smears显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | Am J Pathol2009，175，5： | 1 |
| 5 | Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormalPap smears 显示文摘 | ANDERSSON S SOWJANYA P WANGSA D | 2009 | The American Journal of Pathology2009，175，5： | 1 |
| 6 | Detection of genomic amplification of the haman telomerase gene TERC, a potential marker for triage of women with HPV - positive, abnormal Pap smears 显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | Am J Pathol2009，175，5： | 1 |
| 7 | Comparative genomic hybridization analysis of tonsillar cancer reveals a different pattern of genomic imbalances in human papillomavirus-positive and-negative tumor 显示文摘 | Dahlgren L Mellin H Wangsa D | 2003 | Int J Cancer2003，107，2： | 1 |
| 8 | Detection of genomic amplification of the human telomerase gene TERC,a potential marker for triage of women with HPV-positive,abnormal Pap smears显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | Am J Pathol2009，175，5： | 1 |
| 9 | Detection of genomic amplification of the human telomerase gene TERC,a potential marker for triage of women with HPV-positive,abnormal Pap smears显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | Am J Pathol2009，175，5： | 1 |
| 10 | Comparative genome hybridization reveals specific genomic imbalances during the genesis from benign through borderline to malignant ovarian tumors显示文摘 | Helou K Padilla-Hash H Wangsa D | 2006 | Cancer Genet Cytogenet2006，170，1： | 1 |
| 11 | Detection of genomic amplication of the human telomerase TERC,a potential marker for triage of women with HPV-positive,abnormal Pap smesrs显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | Am J Pathol2009，175，5： | 1 |
| 12 | Detection of genomic aplificationof the haman telomerase gene TERC, a potential mark- er for triage of women with HPV-positive, abnormal Pap smears 显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | Am J Pathol2009，175，： | 1 |
| 13 | Expression of p16INK4a in relation to histopathology and viral load of‘ high - risk' HPV types in cervical neoplastic lesi显示文摘 | ANDERSSON S WANGSA D CARMEN Flores - Staino | 2006 | European journal of cancer2006，42，： | 1 |
| 14 | Detection of genomic amplification of the human telomerase gene TERC,a potential marker for triage of women with HPV-Positive,abnormal pap smears显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | The American Journal of Pathology2009，175，5： | 1 |
| 15 | Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal pap smears显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | Am JPathol2009，175，2： | 1 |
| 16 | Detection of genomic amplification of the human telomerase gene TERC,a potential marker for triage of women with HPV-positive,abnormal Pap smears显示文摘 | Andersson S Sowjanya P Wangsa D | 2009 | Am J Pathol2009，175，5： | 1 |
| 17 | Expression of p16(INK4a) in relation to histopathology and viral load of 'high-risk' HPV types in cervical neoplastic lesions显示文摘 | Andersson S Wangsa D Flores-Staino C | 2006 | Eur J Cancer2006，42，： | 1 |
| 18 | Comparativegenome hybridization reveals specific genomic imbalancesduring the genesis from benign through borderline to ma-lignant ovarian tumors 显示文摘 | Helou K Padilla-Nash H Wangsa D | 2011 | Cancer Genet Cytogenet2011，170，1： | 1 |
| 19 | Fluorescence in situ hy-bridization markers for prediction of cervical lymph node metastases显示文摘 | Wangsa D Heselmeyer-Haddad K Ried P | 2009 | The American journal of pathology2009，175，6： | 1 |
| 20 | Crystallization and pre- liminary X-ray crystallographic analysis of tyrosinase from the mush- room Agaricus bporus 显示文摘 | Wangsa T I Henfiette J R Marloes S | 2011 | Structural Biology and Crystallization Communications2011，67，： | 1 |
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