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| 1 | Role of quorum sensing in bacterial infections显示文摘Quorum sensing(QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate that QS enhances virulence of bacterial pathogens in animal models as well as in human infections; however, its relative importance for bacterial pathogenesis is still incomplete. In this review, we discuss the present evidence from in vitro and in vivo experiments in animal models, as well as from clinical studies, that link QS systems with human infections. We focus on two major QS bacterial models, the opportunistic Gram negative bacteria Pseudomonas aeruginosa and the Gram positive Staphylococcus aureus, which are also two of the main agents responsible of nosocomial and wound infections. In addition, QS communication systems in other bacterial, eukaryotic pathogens, and even immune and cancer cells are also reviewed, and finally, the new approaches proposed to combat bacterial infections by the attenuation of their QS communication systems and virulence are also discussed. | Israel Castillo-Juárez Toshinari Maeda Edna Ayerim Mandujano-Tinoco María Tomás Berenice Pérez-Eretza Silvia Julieta García-Contreras Thomas K Wood Rodolfo García-Contreras | 2015 | World Journal of Clinical Cases2015，3，7： | 15 |
| 2 | 口服抗栓药物预防非瓣膜性房颤患者的卒中:美国心脏协会/美国卒中协会的科学建议显示文摘成年房颤患者的卒中发生率,依据合并症和既往脑血管事件史,为每年1%~20%不等(平均每年为4.5%)。对卒中风险的分层非常重要,因为用抗栓药降低房颤导致卒中的主要风险是出血。如华法令在减少缺血性事件风险的同时,每年有1%~12% | 戴若莲 糜建华 华驾略 董荃 苏爱萍 李焰生 Furie KL Goldstein LB Albers GW Khatri P Neyens R Turakhia MP Turan TN Wood KA | 2012 | 神经病学与神经康复学杂志2012，9，3： | 12 |
| 3 | Safety of epinephrine for anaphylaxis in the emergency setting显示文摘BACKGROUND:While epinephrine is the recommended first-line therapy for the reversal of anaphylaxis symptoms,inappropriate use persists because of misunderstandings about proper dosing and administration or misconceptions about its safety.The objective of this review was to evaluate the safety of epinephrine for patients with anaphylaxis,including other emergent conditions,treated in emergency care settings.METHODS:A MEDLINE search using PubMed was conducted to identify articles that discuss the dosing,administration,and safety of epinephrine in the emergency setting for anaphylaxis and other conditions.RESULTS:Epinephrine is safe for anaphylaxis when given at the correct dose by intramuscular injection.The majority of dosing errors and cardiovascular adverse reactions occur when epinephrine is given intravenously or incorrectly dosed.CONCLUSION:Epinephrine by intramuscular injection is a safe therapy for anaphylaxis but training may still be necessary in emergency care settings to minimize drug dosing and administration errors and to allay concerns about its safety. | Joseph P Wood Stephen J Traub Christopher Lipinski | 2013 | World Journal of Emergency Medicine2013，4，4： | 7 |
| 4 | DNA polymerase zeta (pol ζ) in higher eukaryotes显示文摘 | Gregory N Gan John P Wittschieben Birgitte ф Wittschieben Richard D Wood | 2008 | Cell Research2008，18，1： | 2 |
| 5 | A wind erosion equation显示文摘 | Wood ruff N P Siddoway F H | 1965 | Proc Soil Sci Soc Am1965，，29： | 1 |
| 6 | Extraction of high-viscosty gums from oats显示文摘 | WOOD P J SIDDIQUI L R PATON 19 | 1978 | Cereal Chem1978，55，6： | 1 |
| 7 | Specificity in the interaction of direct dyes with polysaccharides显示文摘 | Wood P J | 1980 | Carbohydr Res1980，85，： | 1 |
| 8 | Identication of pecan cultivars and their genetic relatedness as determined by randomly amplied polymorphic DNA analysis显示文摘 | CONNER P WOOD B | 2001 | J Am Soc Hortic Sci2001，126，： | 1 |
| 9 | Starch biosynthesis in developing wheat grain: evidence against the direct involvemg-at of triose phosphates in the metabolic pathway显示文摘 | Keeling P L Wood J R Tyson R H | 1988 | Plant Physiology1988，87，： | 1 |
| 10 | Corporate Social Responsibility and Stock Market Performance 显示文摘 | Cochran P Wood R | 1984 | Academy of Management Journal1984，27，： | 1 |
| 11 | Film formation and detachment during anodizing of Al-Mg alloys显示文摘 | ZHOU X THOMPSON G E SKELDON P WOOD G C SHIMIZU K HABAZAKI H | 1999 | Corrosion Science1999，41，8： | 1 |
| 12 | 显示文摘 | Rieke P C Marsh B D Wood M L | 1995 | Langmuir1995，11，1： | 1 |
| 13 | Application of MATLAB Functions for Time Domain Simulation of Systems with Lines with Fluid Transients显示文摘 | Wongputorn P Hullender D Woods R | 2005 | Journal of Fluids Engineering2005，127，1： | 1 |
| 14 | Adipokines:inflammation and the pleiotropic role of white adipose tissue显示文摘 | TRAYHURN P WOOD I S | 2004 | Br J Nuti2004，92，3： | 1 |
| 15 | Bilateral sprea- ding cerebral hypoperfusion during spontanesous mi- graine headache显示文摘 | Woods R P Iacoboni M Mazziotta J C | 1994 | N Engl J Med1994，331，25： | 1 |
| 16 | Long- term neuroblast migration along blood vessels in an area with transient angio- genesisand increased vaseularization after stroke显示文摘 | Thored P Wood J Arvidsson A | 2007 | Stroke2007，38，11： | 1 |
| 17 | Pulmonary blasto- ma:a rare childhood malignancy显示文摘 | Senac M O Jr Wood B P Isaacs H | 1991 | Radiology1991，179，3： | 1 |
| 18 | Development of industrial-medium-required elimination of the 2,3-butanediol fermentation pathway to maintain ethanol yield in an ethanologenic strain of Klebsiella oxytoca显示文摘 | WOOD B E YOMANO L P YORK S W | 2005 | Biotechnology Progress2005，21，5： | 1 |
| 19 | Glucose transporters (GLUT and SGLT):expanded families of sugar transport proteins显示文摘 | WOOD I S TRAYHURN P | 2003 | Br J Nutr2003，89，1： | 1 |
| 20 | Algebraic models of the lactation curves for milk, fat and protein production, with estimates of seasonal variation显示文摘 | Wood P D P | 1976 | Animal Production1976，22，： | 1 |
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