|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 男男性接触人群HIV感染趋势分析显示文摘目的为探索北京男男性接触(MSM)人群人类免疫缺陷病毒(HIV)感染率趋势,2004-2006年,在北京MSM人群中进行了连续3年的监测调查。方法使用同伴推动抽样法(Respondent Driven Samlpling,RDS)进行抽样调查及血清学检测,用RDSAT软件进行人群估计。结果2004-2006年分别调查325,427和540名MSM,HIV感染率分别为0.4%(95%CI=0.1-0.8),4.6%(95%CI=2.2-7.6),5.9%(95%CI=3.5-8.7)。伴随HIV感染率上升的还有多性伴、既往性病史和梅毒抗体阳性率及梅毒快速血浆反应素环状卡片试验(RPR)阳性率。结论男男性接触人群HIV感染率正在上升,应采取切实可行的预防措施。 | 马小燕 Mc Farland Willi 张启云 赵金扣 贺雄 李洋 徐敏 孙卫东 黑发新 张琴 杜辉 | 2007 | 中国公共卫生2007，23，11： | 61 |
| 2 | Current and future treatments for hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) represents a unique challenge for physicians and patients.There is no definitively curative treatment.Rather,many treatment and management modalities exist with differing advantages and disadvantages.Both current guidelines and individual patient concerns must be taken into account in order to properly manage HCC.In addition,quality of life issues are particularly complex in patients with HCC and these concerns must also be factored into treatment strategies.Thus,considering all the options and their various pros and cons can quickly become complex for both clinicians and patients.In this review,we systematically discuss the current treatment modalities available for HCC,detailing relevant clinical data,risks and rewards and overall outcomes for each approach.Surgical options discussed include resection,transplantation and ablation.We also discuss the radiation modalities:conformal radiotherapy,yttrium 90 microspheres and proton and heavy ion radiotherapy.The biologic agent Sorafenib is discussed as a promising new approach,and recent clinical trials are reviewed.We then detail currently described molecular pathways implicated in the initiation and progression of HCC,and we explore the potential of each pathway as an avenue for drug exploitation.We hope this comprehensive and forward-looking review enables both clinicians and patients to understand various options and thereby make more informed decisions regarding this disease. | Alexander Schlachterman Willie W Craft Jr Eric Hilgenfeldt Avir Mitra Roniel Cabrera | 2015 | World Journal of Gastroenterology2015，21，28： | 76 |
| 3 | Pathophysiology and prevention of postoperative peritoneal adhesions显示文摘Peritoneal adhesions represent an important clinical challenge in gastrointestinal surgery. Peritoneal adhesions are a consequence of peritoneal irritation by infection or surgical trauma, and may be considered as the pathological part of healing following any peritoneal injury, particularly due to abdominal surgery. The balance between fi brin deposition and degradation is critical in determining normal peritoneal healing or adhesion formation. Postoperative peritoneal adhesions are a major cause of morbidity resulting in multiple complications, many of which may manifest several years after the initial surgical procedure. In addition to acute small bowel obstruction, peritoneal adhesions may cause pelvic or abdominal pain, and infertility. In this paper, the authors reviewed the epidemiology, pathogenesis and various prevention strategies of adhesion formation, using Medline and PubMed search. Several preventive agents against postoperative peri-toneal adhesions have been investigated. Their role aims in activating fi brinolysis, hampering coagulation, diminishing the inflammatory response, inhibiting col-lagen synthesis or creating a barrier between adjacentwound surfaces. Their results are encouraging but most of them are contradictory and achieved mostly in animal model. Until additional fi ndings from future clinical researches, only a meticulous surgery can be recommended to reduce unnecessary morbidity and mortality rates from these untoward effects of surgery. In the current state of knowledge, pre-clinical or clini-cal studies are still necessary to evaluate the effective-ness of the several proposed prevention strategies of postoperative peritoneal adhesions. | Willy Arung Michel Meurisse Olivier Detry | 2011 | World Journal of Gastroenterology2011，17，41： | 46 |
| 4 | 生精障碍的遗传因素显示文摘大概10%-15%的夫妇患有不孕不育,其中,男性因素导致的不育约占一半。部分是由男方的生精障碍导致的,但其根本原因,包括遗传性变异,仍知之甚少。迄今为止,男性不育症诊断中使用的唯一基因测试的目的是检测是否存在Y染色体长臂的微缺失或者染色体异常。各种其他单基因和多基因缺陷也己被提出与男性生育能力相关。但其致病作用仍有待验证。最近,全基因组技术和小鼠模型的大规模分析方面所取得的巨大进步可能有助于这方面的研究。利用基因敲除小鼠模型,至少有388个基因与小鼠生精相关的基因被发现了。但当前的主要问题在于如何把这些研究成果从小鼠转移应用到人类。 | Annelien Massart Willy Lissens Herman Tournaye Katrien Stouffs | 2012 | Asian Journal of Andrology2012，14，1： | 36 |
| 5 | 非均衡劳动力市场的真实经济周期模型显示文摘真实经济周期(RBC)模型通常以市场出清的一般均衡为其理论框架。这使我们无法有效的将这一跨时期的动态优化模型应用于现实的经济环境,因为现实的世界里普遍存在着各种非均衡的状况。本文将劳动的供给和需求分离开来,从而允许非均衡的劳动力市场存在。利用美国的数据,我们对该模型进行了实证检验,结果表明该模型能够更好的解释劳动力市场的波动及消费和就业间的关系,同时说明该模型在数据的拟和上比标准RBC模型更好。 | 龚刚 Willi Semmler | 2003 | 经济学(季刊)2003，2，3： | 20 |
| 6 | Performance of liver stiffness measurements by transient elastography in chronic hepatitis显示文摘AIM:To compare results of liver stiffness measurements by transient elastography(TE) obtained in our patients population with that used in a recently published meta-analysis.METHODS:This was a single center cross-sectional study.Consecutive patients with chronic viral hepatitis scheduled for liver biopsy at the outpatient ward of our Infectious Diseases Department were enrolled.TE was carried out by using FibroScan(Echosens,Paris,France).Liver biopsy was performed on the same day as TE,as day case procedure.Fibrosis was staged according to the Metavir scoring system.The diagnostic performance of TE was assessed by using receiver operating characteristic(ROC) curves and the area under the ROC curve analysis.RESULTS:Two hundred and fifty-two patients met the inclusion criteria.Six(2%) patients were excluded due to unreliable TE measurements.Thus,246(171 men and 75 women) patients were analyzed.One hundred and ninety-five(79.3%) patients had chronic hepatitis C,41(16.7%) had chronic hepatitis B,and 10(4.0%) were coinfected with human immunodeficiency virus.ROC curve analysis identified optimal cut-off value of TE as high as 6.9 kPa forF ≥ 2;7.9 kPa forF ≥ 3;9.6 kPa for F = 4 in all patients(n = 246),and as high as 6.9 kPa for F ≥ 2;7.3 kPa for F ≥ 3;9.3 kPa for F = 4 in patients with hepatitis C(n = 195).Cut-off values of TE obtained by maximizing only the specificity were as high as 6.9 kPa for F ≥ 2;9.6 kPa for F ≥ 3;12.2 kPa for F = 4 in all patients(n = 246),and as high as 7.0 kPa forF ≥ 2;9.3 kPa forF ≥ 3;12.3 kPa forF = 4 in patients with hepatitis C(n = 195).CONCLUSION:The cut-off values of TE obtained in this single center study are comparable to that obtained in a recently published meta-analysis that included up to 40 studies. | Giovanna Ferraioli Carmine Tinelli Barbara Dal Bello Mabel Zicchetti Raffaella Lissandrin Gaetano Filice Carlo Filice Elisabetta Above Giorgio Barbarini Enrico Brunetti Willy Calderon Marta Di Gregorio Roberto Gulminetti Paolo Lanzarini Serena Ludovisi Laura Maiocchi Antonello Malfitano Giuseppe Michelone Lorenzo Minoli Mario Mondelli Stefano Novati Savino FA Patruno Alessandro Perretti Gianluigi Poma Paolo Sacchi Domenico Zanaboni Marco Zaramella | 2013 | World Journal of Gastroenterology2013，19，1： | 18 |
| 7 | 采用同伴推动抽样法进行男男性接触人群HIV/STD流行病学调查的探索显示文摘目的探索同伴推动抽样法(Respondent driven sampling,RDS)在我国男男性接触(MSM)人群调查的可行性。方法使用RDS对北京市MSM进行抽样调查及血清学检测,了解他们艾滋病病毒(HIV)、性病感染状况及行为特点;采用RDSAT软件进行统计分析,NETDRAW和EXCEL作图。结果共征募MSM 325人,其中35岁以下占90.5%,未婚占83.0%(95%CI:76.4~88.9),外地户籍为61.9%(95%CI:54.0~70.1);HIV感染率为0.4%(95%CI:0.1~0.5),梅毒抗体阳性率为13.7%(95%CI:9.1~19.0),梅毒RPR阳性率6.0%(95%CI:3.8~8.7);56.2%(95%CI:50.0~65.0)为男性性取向,88.9%首次性行为年龄≤24岁,56.3%(95%CI:49.5~64.0)半年内有≥2个性伴,近6个月无保护插入性肛交为51.8%(95%CI:44.0~59.4),无保护被插入性肛交为44.8%(95%CI:37.2~52.3)。结论RDS简便易行,无需过多凋查员投入前期准备工作,实为开展隐匿人群调查的行之有效的方法之一。北京市MSM人群HIV感染率可能处于低水平.但存在HIV行隐患。 | 马小燕 张启云 赵金扣 贺雄 杜辉 孙卫东 张琴 郭雅琦 Mac Farland Willi | 2007 | 中国艾滋病性病2007，13，4： | 18 |
| 8 | OLAND生物脱氮系统运行及其硝化菌群的分子生物学检测显示文摘采用两阶段限氧自养硝化 -反硝化生物脱氮系统 (oxygen limitedautotrophicnitrificationanddenitrificationsystem ,以下简称OLAND)处理高氨氮、低COD的废水 .应用内浸式多聚醚砜中空膜 ,实现了污泥的完全截留 ,阻止了生物量的大量洗脱 ,并通过控制溶氧在 0 .1~ 0 .3mgL-1之间 ,实现了硝化阶段出水中氨氮与亚硝态氮浓度的比例达到最适值〔1 (1.2± 0 .2 )〕 ,从而为第二阶段的厌氧氨氧化提供理想的进水 ,进而获得较高的脱氮率 .同时应用荧光原位杂交技术对硝化阶段不同时期硝化菌群的变化进行分子生物学检测 ,揭示了随溶氧浓度的降低 ,氨氧化菌的数量基本保持恒定、亚硝酸氧化菌的数量略有减少的变化规律 ,并且发现 ,在两阶段限氧自养硝化 -反硝化生物脱氮系统中氨氮的氧化主要是由Nitrosomonassp .完成 ,亚硝酸的氧化主要由Nitrobactersp .完成 .图 4表 2参 2 | 张丹 徐慧 刘耀平 张颖 陈冠雄 van Cleemput Oswald Verstraete Willy | 2003 | 应用与环境生物学报2003，9，5： | 17 |
| 9 | Endoscopic pancreatic sphincterotomy:indications,outcome,and a safe stentless technique显示文摘Endoscopicpancreaticsphincterotomy:indications,outcome,andasafestentlesstechniquericElton,MD,DouglasA.Howel,MD,WilisG.Parsons... | Eric Elton, MD, Douglas A. Howell, MD, Willis G. Parsons, MD, Tahir Qaseem, MD, Brian L. Hanson, MDPortland, MaineDivision of Gastroenterology, Maine Medical Center, Portland, Maine | 1998 | World Journal of Gastroenterology1998，4，3： | 16 |
| 10 | 空间规划的三个目标:可持续发展、社会福利、善治显示文摘当前.空间冲突不仅在数量上不断增加.而且也日益复杂.这是由于人口以及各种活动的增长不断加大了对空间的需求而导致的直接结果。因为空间(space)是不能被制造的.对于这一人类不可或缺的资源.我们应该特别关注,因此综合性和持续性的规划是必不可少的。 | Willy A.Schmid | 2006 | 国外城市规划2006，21，6： | 15 |
| 11 | 参与式新闻的兴起显示文摘本文详细介绍参与式新闻的特点,发生发展的过程,并具体分析了它兴起的原因和社会背景,着重从传播、媒介、受众这三个传播链上的环节来探讨参与性新闻的特性。 | Shayne Bowman Chris Willis 欧阳俊杰 | 2009 | 中华文化论坛2009，，S1： | 13 |
| 12 | 大气颗粒物中元素碳的直接测定显示文摘对原来用元素分析仪测定大气颗粒物样品中有机碳、元素碳的方法[1 ] 进行改进 ,将差减法间接测定元素碳改为一步直接测定元素碳。有机碳、元素碳的测量标准偏差的平均值分别为 0 35 %、0 34% ,提高了元素碳的测量精度 ,同时避免了误差传递 ,解决了差减法测定元素碳时出现负值的情况。 | 董树屏 刘咸德 祁辉 张烃 Willy Manhaunt | 2004 | 中国环境监测2004，20，3： | 12 |
| 13 | Free-breathing radial volumetric interpolated breathhold examination vs breath-hold cartesian volumetric interpolated breath-hold examination magnetic resonance imaging of the liver at 1.5T显示文摘AIM: To compare breath-hold cartesian volumetric interpolated breath-hold examination(cVIBE) and freebreathing radial VIBE(rVIBE) and determine whether rVIBE could replace cVIBE in routine liver magnetic resonance imaging(MRI).METHODS: In this prospective study, 15 consecutive patients scheduled for routine MRI of the abdomen underwent pre- and post-contrast breath-hold cVIBE imaging(19 s acquisition time) and free-breathing rVIBE imaging(111 s acquisition time) on a 1.5T Siemens scanner. Three radiologists with 2, 4, and 8 years post-fellowship experience in abdominal imaging evaluated all images. The radiologists were blinded to the sequence types, which were presented in a random order for each patient. For each sequence, the radiologists scored the cVIBE and rVIBE images for liver edge sharpness, hepatic vessel clarity, presence of artifacts, lesion conspicuity, fat saturation, and overall image quality using a five-point scale. RESULTS: Compared to rVIBE, cVIBE yielded significantly(P < 0.001) higher scores for liver edge sharpness(mean score, 3.87 vs 3.37), hepatic-vessel clarity(3.71 vs 3.18), artifacts(3.74 vs 3.06), lesion conspicuity(3.81 vs 3.2), and overall image quality(3.91 vs 3.24). cVIBE and rVIBE did not significantly differ in quality of fat saturation(4.12 vs 4.03, P = 0.17). The inter-observer variability with respect to differences between rVIBE and cVIBE scores was close to zero compared to random error and inter-patient variation. Quality of rVIBE images was rated as acceptable for all parameters. CONCLUSION: rVIBE cannot replace cVIBE in routine liver MRI. At 1.5T, free-breathing rVIBE yields acceptable, although slightly inferior image quality compared to breath-hold cVIBE. | Sireesha Yedururi HyunSeon C Kang Wei Wei Nicolaus A Wagner-Bartak Leonardo P Marcal R Jason Stafford Brandy J Willis Janio Szklaruk | 2016 | World Journal of Radiology2016，8，7： | 9 |
| 14 | Comparative short-term effects of sewage sludge and its biochar on soil properties, maize growth and uptake of nutrients on a tropical clay soil in Zimbabwe显示文摘Soil application of biochar from sewage could potentially enhance carbon sequestration and close urban nutrient balances. In sub-Saharan Africa, comparative studies investigating plant growth effect and nutrients uptake on tropical soils amended with sewage sludge and its biochar are very limited. A pot experiment was conducted to investigate the effects of sewage sludge and its biochar on soil chemical properties, maize nutrient and heavy metal uptake, growth and biomass partitioning on a tropical clayey soil. The study compared three organic amendments; sewage sludge(SS), sludge biochar(SB) and their combination(SS+SB) to the unamended control and inorganic fertilizers. Organic amendments were applied at a rate of 15 t ha^(–1) for SS and SB, and 7.5 t ha^(–1) each for SS and SB. Maize growth, biomass production and nutrient uptake were significantly improved in biochar and sewage sludge amendments compared to the unamended control. Comparable results were observed with F, SS and SS+SB on maize growth at 49 d of sowing. Maize growth for SB, SS, SS+SB and F increased by 42, 53, 47, and 49%, respectively compared to the unamended control. Total biomass for SB, SS, SS+SB, and F increased by 270, 428, 329, and 429%, respectively compared with the unamended control. Biochar amendments reduced Pb, Cu and Zn uptakes by about 22% compared with sludge alone treatment in maize plants. However, there is need for future research based on the current pot experiment to determine whether the same results can be produced under field conditions. | Willis Gwenzi Moreblessing Muzava Farai Mapanda Tonny P Tauro | 2016 | Journal of Integrative Agriculture2016，15，6： | 9 |
| 15 | Methods for discovery and characterization of cellulolytic enzymes from insects显示文摘 | Jonathan D. Willis Cris Oppert Juan L. Jurat-Fuentes | 2010 | Insect Science2010，17，3： | 8 |
| 16 | Endophytic species of Colletotrichum associated with mango in northeastern Brazil显示文摘Endophytic species of Colletotrichum associated with Mangifera indica(mango)are poorly understood.In this study,Colletotrichum species were isolated from mango in Pernambuco State,Brazil.There were significant differences in isolation frequencies of Colletotrichum species among sites and plant tissues.Mature leaf blades were colonized by most Colletotrichum isolates at the majority of sites.Partial sequences of glyceraldehyde-3-phosphate dehydrogenase(GAPDH)of 97 Colletotrichum isolates were amplified as an initial measure of genetic diversity.Phylogenetic analysis with a subset of 22 isolates were performed based on a multilocus dataset(ACT,TUB2,CAL,CHS-1,GAPDH,ITS)followed by Apn2/MAT IGS sequence-analysis for isolates within the C.gloeosporioides species complex.Molecular analysis associated with phenotypic characteristics revealed six previously described species[C.asianum,C.cliviae,C.dianesei(syn.C.melanocaulon),C.fructicola,C.karstii and C.tropicale]and one new species.This new species is introduced as C.endomangiferae.All species isolated were pathogenic on mango fruits but varied in their virulence.There was no distribution pattern of species among sites and plant tissues,although C.asianum was the most prevalent species at all sites and in all plant tissues studied.Five previously reported Colletotrichum species causing anthracnose in mango fruits in northeastern Brazil were also recovered as endophytes. | Willie A.S.Vieira Sami J.Michereff Marcos A.de Morais Jr Kevin D.Hyde Marcos P.S.Camara | 2014 | Fungal Diversity2014，，4： | 6 |
| 17 | 文化混搭对群体心理融合的影响:经验开放性的调节作用显示文摘心理融合是积极群际关系的表征,是构建和谐社会不可或缺的重要前提。基于群际接触理论,通过两个实验考察了文化混搭对心理融合的影响及其调节因素。实验采用4×2两因素组间设计,先测量被试经验开放性,然后操纵文化混搭,并使用双向社会距离量表(实验一、实验二)和街道距离投射测验(实验二)测量外显和内隐心理融合水平。结果表明,文化混搭不仅能促进外显心理融合也能提升内隐心理融合,经验开放性在其中起调节作用——文化混搭对高经验开放者心理融合有促进作用,对低经验开放者则无显著影响。该结果不仅丰富了心理融合研究,拓展了群际接触理论,也为实践中群体关系管理提供了一定的理论指导。 | 赵玉芳 包燕 肖子伦 李骐 Willie Njoroge 梁芳美 | 2020 | 辽宁师范大学学报(社会科学版)2020，43，4： | 6 |
| 18 | Developing crop specific area frame stratifications based on geospatial crop frequency and cultivation data layers显示文摘Area Sampling Frames(ASFs) are the basis of many statistical programs around the world. To improve the accuracy,objectivity and efficiency of crop survey estimates,an automated stratification method based on geospatial crop planting frequency and cultivation data is proposed. This paper investigates using 2008–2013 geospatial corn,soybean and wheat planting frequency data layers to create three corresponding single crop specific and one multi-crop specific South Dakota(SD) U.S. ASF stratifications. Corn,soybeans and wheat are three major crops in South Dakota. The crop specific ASF stratifications are developed based on crop frequency statistics derived at the primary sampling unit(PSU) level based on the Crop Frequency Data Layers. The SD corn,soybean and wheat mean planting frequency strata of the single crop stratifications are substratified by percent cultivation based on the 2013 Cultivation Layer. The three newly derived ASF stratifications provide more crop specific information when compared to the current National Agricultural Statistics Service(NASS) ASF based on percent cultivation alone. Further,a multi-crop stratification is developed based on the individual corn,soybean and wheat planting frequency data layers. It is observed that all four crop frequency based ASF stratifications consistently predict corn,soybean and wheat planting patterns well as verified by the 2014 Farm Service Agency(FSA) Common Land Unit(CLU) and 578 administrative data. This demonstrates that the new stratifications based on crop planting frequency and cultivation are crop type independent and applicable to all major crops. Further,these results indicate that the new crop specific ASF stratifications have great potential to improve ASF accuracy,efficiency and crop estimates. | Claire G. Boryan Zhengwei Yang Patrick Willis Liping Di | 2017 | Journal of Integrative Agriculture2017，16，2： | 5 |
| 19 | 零价钯催化下赤霉素A_3衍生物A环的反应显示文摘在 ( Ph3P) 4Pd( 0 )催化下 ,赤霉素 A3( GA3)衍生物的 A环在氢供体环己烯存在时发生氢解 ,形成 1,3-二烯主产物 ;而在无氢供体时则发生 A环的芳构化反应 .通过选择适当的反应条件 ,可以得到不同主要产物 . | 陈安齐 Christine L Willis | 2001 | 厦门大学学报(自然科学版)2001，40，1： | 4 |
| 20 | A Provable Secure ID-Based Explicit Authenticated Key Agreement Protocol Without Random Oracles显示文摘In this paper, we present an identity-based explicit authenticated key agreement protocol that is provably secure without random oracles. The protocol employs a new method to isolate a session key from key confirmation keys so that there is no direct usage of hash functions in the protocol. The protocol is proved secure without random oracles in a variant of Bellare and Rogaway style model, an exception to current proof method in this style model in the ID-based setting. We believe that this key isolation method is novel and can be further studied for constructing more effcient protocols. | 田海博 Willy Susilo 明洋 王育民 | 2008 | Journal of Computer Science & Technology2008，23，5： | 4 |
您所在的机构暂未开通此部分的功能，请联系管理员