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| 1 | 如何将小胶质细胞向有益功能重编程显示文摘小胶质细胞是一种非神经起源的脑细胞,它可以协调对各种损伤的炎症反应,包括围产期脑中的缺氧/缺血或母体/胎儿感染。实验研究已经证明小胶质细胞能够识别病原体或受损细胞,从而激活细胞毒性反应,从而加剧脑损伤。然而,小胶质细胞在对损伤的反应中显示出巨大的可塑性,并且还可以促进炎症和组织再生的消退。尽管小胶质细胞在脑病理学中起着关键作用,对于控制小胶质细胞不同表型的细胞机制的研究却才刚刚崭露头角。这篇文章回顾了推动小胶质细胞向有益功能发展的新兴策略,总结了涉及表型转换潜在的分子机制的研究。这些方法包括使用药理学试剂,细胞因子,脂质信使或微小RNA,以及免疫调节细胞的营养方法或疗法来处理小胶质细胞。对小胶质细胞向促再生功能重编程相关的分子机制的分析指出,能量代谢在塑造小胶质细胞功能中起到核心作用。因此,可以通过调控代谢途径,来预防炎性小胶质细胞的有害作用并控制脑病症中的过度炎症反应。 | Fumagalli M Lombardi M Gressens P Verderio C 聂昊 | 2018 | 神经损伤与功能重建2018，13，10： | 10 |
| 2 | Synaptic and intrinsic mechanisms shape synchronous oscillations in hippocampal neurons in culture显示文摘 | Bacci A Verderio C Pravettoni E Matteoli M | 1999 | Eur J Neurosci1999，11，： | 1 |
| 3 | Predictors of perinatal survival in a cohort of pregnancies with severe oligohydramnios due to premature rupture of membranes at 《 26 weeks managed with serial amnioinfusions显示文摘 | Locatelli A Ghidini A Verderio M | 2006 | Eur J Obstet Gynecol Reprod Biol2006，128，12： | 1 |
| 4 | ATP mediates calcium singnaling between astrocytes and microglial cells: modulation by IFN-γ显示文摘 | Verderio C Matteoli M | 2001 | J Immunol2001，166，： | 1 |
| 5 | Premature rupture of the membranes at <26 weeks'gestation:role of amnioinfusion in the man- agement of oligohydramnios 显示文摘 | Vergani P Locatelli A Verderio M | 2004 | Acts Biomed2004，75，11： | 1 |
| 6 | Prognostic value of intratumoral microvessel density, a measure of tumor angio- genesis,in node - negative breast carcinoma - - results of a muhiparametric study 显示文摘 | Bevilacqua P Barbareschi M Verderio P | 1995 | Breast Cancer Res Treat1995，36，2： | 1 |
| 7 | Vesicular transmitter release from astrocytes 显示文摘 | Montana V Malarkey EB Verderio C Matteoli M Parpura V | 2006 | Glia2006，54，7： | 1 |
| 8 | Prognostic value of intratumoral microvessel density,a measure of tumor angiogenesis in node-negative breast carcinoma,results of a multiparametric study 显示文摘 | Bevilacqua P Barbareschi M Verderio P | 1995 | Breast Cancer Res Treat1995，36，2： | 1 |
| 9 | Quality of surgery and neo- adjuvant combined therapy in the ISG-GEIS trial on soft tissue sarco- mas of limbs and trunk wall显示文摘 | Groncbi A Verderio P De Paoh A | 2013 | Ann Oncol2013，24，3： | 1 |
| 10 | Predictors of perinatal survival in a cohort of pregnancies with severe oligohydramnios due to premature rupture of membranes at < 26 weeks managed with serial amnioinfusions 显示文摘 | Locatelli A Ghidini A Verderio M | 2006 | Eur J Obstet Gynecol Reprod Biol2006，128，12： | 1 |
| 11 | Premature rupture of the membranes at < 26 weeks' gestation : role of amnioinfusian in the management of oligohydramnios显示文摘 | Verqani P Loeatelli A Verderio M | 2004 | Acta Biomed2004，75，： | 1 |
| 12 | Block of Glutamate-Glutamine Cycle Between Astrocytes and Neurons Inhibits Epileptiform Activity in Hippocampus显示文摘 | Alberto Bacci Giulio Sancini Claudia Verderio | 2002 | J Neurophysiol2002，88，： | 1 |
| 13 | Cyto toxicity of Some Calalysts Commonly Used in the Synthe sis of Copolymers for Biomedical Use显示文摘 | Tanzi M C Verderio P Lampugmani M G | 1994 | J Mater Sci Mater Med1994，5，67： | 1 |
| 14 | Intemalization and mecha- nism of action of clostridial toxins in neurons 显示文摘 | Grumelli C Verderio C Pozzi D | 2005 | Neurotoxicology2005，26，5： | 1 |
| 15 | PI3KCA mutation sta- tus is of limited prognostic relevance in ER-positive breast cancer pa- tients treated with hormone therapy 显示文摘 | Cuorvo L V Verderio P Ciniselli C M | 2014 | Virchows Archiv2014，464，1： | 1 |
| 16 | Preparation of Poly(D, L-lactide-co-glycolide) Latex for Surface-modifying Material by a Double Coacervation Method显示文摘 | Tanzi C Verderio P | 1994 | J Mater Sci1994，，5： | 1 |
| 17 | Microglia-oligodendrocyte intercellular communication: role of extracellular vesicle lipids in functional signalling显示文摘The term microglia refers to the group of resident brain immune-cells that are responsible,mainly,for the immune response and the homeostasis of the brain.Unlike monocyte-derived macrophages that infiltrate the brain,microglia are longlived cells which arise exclusively from the embryonic yolk sac(Stratoulias et al.,2019).Impairment in microglia functions is at the basis for the development of multiple brain diseases,including multiple sclerosis and neurodegenerative diseases.In the last decade,the number of research articles and reviews dealing with the role of microglia in the pathogenesis of brain disorders has exponentially increased. | Alice Gualerzi Marta Lombardi Claudia Verderio | 2021 | Neural Regeneration Research2021，16，6： | 1 |
| 18 | The role of glialcells in sgnaptic function 显示文摘 | Bacci A Verderio C Pravettoni E | 1999 | Phitos Trans R SocLond B Bi- ol Sci1999，354，1381： | 1 |
| 19 | Preparation ofpoly (D,L-lactide-co-glycolide)latex for surface-modifying material by a double coacervation method显示文摘 | Verderio P | 1994 | J Mater Sci1994，，5： | 1 |
| 20 | Premature rupture of membranes at《26 weeks management with serial amioinfusions显示文摘 | Locatel i A Ghidini A verderio M | | 0，，1： | 1 |
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