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| 1 | Comparison of hyaluronidase expression, invasiveness and tubule formation promotion in ER (-) and ER (+) breast cancer cell lines in vitro显示文摘背景玻尿酸酵素(Hyase ) 是酶哪个 hydrolyses hyaluronan (哈) ,大 nonsulfated glycosaminoglycan。几基因在人为玻尿酸酵素被识别了到代码。它的角色仅仅最近在前列腺癌症,结肠的癌症,和乳癌的侵略被加重了。而且,调查结果与证明哈导出 oligosaccharides 有支持 angiogenesis 的一些试验性的结果一致活动。所有这些调查结果提示了我们调查在不同的人的胸作为通常认为的侵略因素被描绘了的因素我们选择了的导出癌症的房间 lines.Methods 雌激素受体的表示的导出癌症的房间排队的人的胸的二个系列(嗯) 以前被出版。在文化媒介和矩阵 metallo 朊酶(MMP ) 的表示的玻尿酸酵素分泌物 -9, cathepsin-D (cath-D ) 和由房间的脉管的 endothelial 生长因素(VEGF ) 被决定。我们也在 Matrigel 侵略试金调查了房间侵略,并且学习了癌症房间的能力由 endothelial cells.Results 在小管的 vitro 形成支持嗯(-)房间显著地分泌了更多的玻尿酸酵素( P < 0.001 )并且显著地表示了更多的 VEGF ( P < 0.01 ), MMP-9 ( P < 0.05 )并且 cath-D ( P < 0.0001 )比嗯(+)房间。通过 Matdgel 由的侵略嗯(-) Hyase (+) 房间比那显著地高由嗯(+) Hyase (-) 房间(P < 0.05 ) 。在两个盒子中,侵略被肝磷脂减少(P < 0.05 ) 。当 ECV-304 endothelial 房间与癌症房间在 millicell 房间被共同栽培时, ECV-304 房间被导致形成小管。小管形成被表明更突出与嗯(-) Hyase (+)房间比与嗯(+) Hyase (-)房间( P < 0.05 ) .Conclusion 侵略特征嗯(-)乳癌房间能被侵略 Matrigel 试金在 vitro 描绘,作为由 ECV-304 endothelial 房间,玻尿酸酵素的更高的分泌物,和支持因素 VEGF 的朊酶 MMP-9 , cath-D ,和 angiogenesis 的更高的表示的小管形成的正式就职。 | WANG Xiao-yi TAN Jin-xiang Marc Vasse Bertrand Delpech REN Guo-sheng | 2009 | Chinese Medical Journal2009，，11： | 3 |
| 2 | Frequency and prognostic role of mucosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy显示文摘AIM:To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatment after stopping the biologicals in patients with Crohn’s disease(CD)and ulcerative colitis(UC).METHODS:The data from 41 patients with CD and 22 patients with UC were assessed.Twenty-four CD patients received infliximab,and 17 received adalimumab.The endoscopic severity of CD was quantified with the simplified endoscopic activity score for Crohn’s disease in CD and with the Mayo endoscopic subscore in UC.RESULTS:Mucosal healing was achieved in 23 CD and7 UC patients.Biological therapy had to be restarted in78%of patients achieving complete mucosal healing with CD and in 100%of patients with UC.Neither clinical remission nor mucosal healing was associated with the time to restarting the biological therapy in either CD or UC.CONCLUSION:Mucosal healing did not predict sustained clinical remission in patients in whom the biological therapies had been stopped. | Klaudia Farkas Péter László Lakatos Mónika Szcs va Pallagi-Kunstár Anita Bálint Ferenc Nagy Zoltán Szepes Noémi Vass Lajos S Kiss Tibor Wittmann Tamás Molnár | 2014 | World Journal of Gastroenterology2014，20，11： | 2 |
| 3 | 艾滋病已成为世界第四大杀手显示文摘 | Alex Vass 付晓霞 | 2002 | 英国医学杂志中文版2002，5，3： | 2 |
| 4 | Regulation of fibrinogen biosynthesis by cytokines, conse- quences on the vascular risk 显示文摘 | VASSE M PAYSANT J SORIA J COLLET JP VANNIER JP SO- RIA C | 1996 | Haemostasis1996，26，： | 1 |
| 5 | Demethylation of the MCJ gene in stage Ill/IV epithelial ovarian cancer and re- sponse to chemotherapy 显示文摘 | Strathdee G Vass JK Oien KA | 2005 | Gynecol Oncol2005，97，： | 1 |
| 6 | In-house validation of an ELISA method for screening of semicarbazide in eggs 显示文摘 | Vass M Diblikova L Kok E | 2008 | Food Ad- di Conta2008，25，8： | 1 |
| 7 | ELISA for semicarbazide and its application for screening in food contamination 显示文摘 | Vass M Diblikova I Cernoch I | 2008 | Anal Chim Acta2008，608，1： | 1 |
| 8 | Step-and-shoot data acquisition and reconstruction for cardiac X-ray computed tomography显示文摘 | Hsieh J Londt J Vass M | 2006 | Med Phys2006，33，11： | 1 |
| 9 | What's a good doctor and how can you make one?显示文摘 | | 2002 | BMJ2002，325，： | 1 |
| 10 | Significance-linked connected component analysis for very low Bit-rate wavelet video coding显示文摘 | Jozsef Vass Chai Bingbing | 1999 | IEEE Transactions on Circuits and Systems for Video Technology1999，9，6： | 1 |
| 11 | Significance-linked connected component analysis for wavelet image coding显示文摘 | ChaiBB Vass J | 1999 | IEEE Trans Image Processing1999，8，6： | 1 |
| 12 | differential Requirements for MCM proteins in DNA replication in drosophila S2 cell显示文摘 | Grevel G Hashimoto R Vass S | 2007 | PLoS ONE2007，2，9： | 1 |
| 13 | Thrombocytosis of liv- er metastasis from colorectal cancer as predictive factor显示文摘 | Josa V Krzystanek M Vass T | 2015 | Pathol Oncol Res2015，21，4： | 1 |
| 14 | Implementation of Technology and Relationships to Supply Chain Performance:Apparel Manufac-turers'Perspectives显示文摘 | Vass D Cassill N L | 2001 | The International Review of Retail Distil-bution and Consumer Research2001，11，3： | 1 |
| 15 | Frequency of proteinZ deficiency in patients with ischaemic stroke显示文摘 | Vasse M Guegan-Massardier E Borg J Y | 2001 | Lancet2001，357，9260： | 1 |
| 16 | Hypertrophic chronic pachymeningitis as a localized immune process in the craniocervical region显示文摘 | Voller B Vass K Wanschitz J | 2001 | Neurology2001，56，1： | 1 |
| 17 | Frequency of protein Z deficiency in patients with ischaemic stroke显示文摘 | Vasse M Guegan-Massardier E Borg JY | 2001 | Lancet2001，357，9260： | 1 |
| 18 | Decomposition chemistry of human remains:A new methodology for determining the postmortem interval 显示文摘 | Vass AA Barshick SA Sega G | 2002 | J Forensic Sci2002，47，3： | 1 |
| 19 | Modifying subsceral fluid pressure in an experimental model of mitomycin C diffusion显示文摘 | Georgopoulos M Vass C Vatanparast Z | 2002 | Exp Eye Res2002，75，6： | 1 |
| 20 | Production and characterisation of monoclonal antibodies for the detection of AOZ,a tissue bound metabolite of furazolidone显示文摘 | VASS M KOTKOVA L DIBLIKOVA I | 2005 | Vet Med Czech2005，50，7： | 1 |
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