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| 1 | Value of a comprehensive geriatric assessment for predicting one-year outcomes in patients undergoing transcatheter aortic valve implantation: results from the CGA-TAVI multicentre registry显示文摘Background In a three-month report from the CGA-TAVI registry, we found the Multidimensional Prognostic Index (MPI) and Short Physical Performance Battery (SPPB) to be of value for predicting short-term outcomes in elderly patients undergoing transcatheter aortic valve implantation (TAVI). In the present analysis, we examined the association of these tools with outcomes up to one year post-TAVI. Methods CGA-TAVI is an international, observational registry of geriatric patients undergoing TAVI. Patients were assessed using the MPI and SPPB. Efficacy of baseline values and any postoperative change for predicting outcome were established using logistic regression. Kaplan- Meier analysis was carried out for each comprehensive geriatric assessment tool, with survival stratified by risk category. Results One year after TAVI, 14.1% of patients deceased, while 17.4% met the combined endpoint of death and/or non-fatal stroke, and 37.7% the combined endpoint of death and/or hospitalisation and/or non-fatal stroke. A high-risk MPI score was associated with an increased risk of all-cause mortality (aOR = 36.13, 95% CI: 2.77–470.78, P = 0.006) and death and/or non-fatal stroke (aOR = 10.10, 95% CI: 1.48–68.75, P = 0.018). No significant associations were found between a high-risk SPPB score and mortality or two main combined endpoints. In contrast to a worsening SPPB, an aggravating MPI score at three months post-TAVI was associated with an increased risk of death and/or non-fatal stoke at one year (aOR = 95.16, 95% CI: 3.41–2657.01). Conclusions The MPI showed value for predicting the likelihood of death and a combination of death and/or non-fatal stroke by one year after TAVI in elderly patients. | Martijn S.van Mourik Nathalie van der Velde Giulio Mannarino Marie-Pierre Thibodeau Jean-Bernard Masson Gennaro Santoro Jan Baan Sofie Jansen Jana Kurucova Martin Thoenes Cornelia Deutsch ANDreas W.Schoenenberger ANDrea Ungar Peter Bramlage M Marije Vis | 2019 | Journal of Geriatric Cardiology2019，16，6： | 3 |
| 2 | Sleep, excessive daytime sleepiness and fatigue in Parkinson's disease显示文摘 | Hilten JJ Weggeman M Velde EA | 1993 | Neural Transm1993，5，： | 2 |
| 3 | Identification and characterization of the cps locus of Streptococcus suis serotype 2: the capsule protects against phagocytosis and is an important virulence factor显示文摘 | Smith HE Damman M van der Velde J | 1999 | Infect Immun1999，67，4： | 1 |
| 4 | Intrathecal sufentanil and fetal heart rate abnormalities:a double-blind,double placebo-controlled trial comparing two forms of combined spinal epidural analgesia with epidural analgesia in labor显示文摘 | VAN DE VELDE M TEUNKENS A HANSSENS M | 2004 | Anesth Analg2004，98，4： | 1 |
| 5 | Associ- ation of estimated glomerular filtration rate and albuminu- ria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis 显示文摘 | Matsushita K van tier Velde M Astor BC | 2010 | Lancet2010，375，9731： | 1 |
| 6 | Inflammatory signal transduction in Crohn's disease and novel therapeutic approaches显示文摘 | Van Montfrans C Peppelenbosch M Te Velde A A | 2002 | Biochem Pharmacol2002，64，： | 1 |
| 7 | Effects of formoterol (Oxis turbuhaler) and ipratopium on exercise capacity in patients with COPD显示文摘 | Liesker JJ De velde V Meysman M | 2002 | Respir Med2002，96，8： | 1 |
| 8 | An achaete-scute hom-ologue essential for neuroendocrine differentiation in the lung显示文摘 | Borges M Linnoila RI van de Velde HJ | 1997 | Na-ture1997，386，6627： | 1 |
| 9 | Remifentanil for fetal immobilization and maternal sedation during fetoscopic surgery : A randomized, double-blind comparison with diazepam 显示文摘 | Van de Velde M Schoubroeck D Lewi LE | 2005 | Anesth Analg2005，101，1： | 1 |
| 10 | Bringing a probiotic- containing functional food to the market: microbiological, product, regulatory and labeling issues显示文摘 | Sanders M Huis in' t Veld J | 1999 | Antonie van Leeuwenhoek1999，76，： | 1 |
| 11 | Efficient gene ration and amplification of high-capacity adeno-associated virus Padenovirus hybrid vectors显示文摘 | Goncalves M A vander Velde I Janssen J M | 2002 | J Virol2002，76，10： | 1 |
| 12 | Neuronspecific enolase as a marker of brain metastasis in patients with small-cell lung carcinoma显示文摘 | Van de Pol M Tgwijnstra A Ten Velde G P | 1994 | J Neurooncol1994，19，2： | 1 |
| 13 | A multicentre trial comparing different concentrations of ropivacaine plus sufentanil with bupivacaine plus sufentanil for patient-controlled epidural analgesia in labour显示文摘 | Gogarten W van de Velde M Soetens E | 2004 | Eur J Anaesthesiol2004，21，1： | 1 |
| 14 | Identification and charac-terization of the cps locus of Streptococcus suis serotype 2: the capsulcprotects against phagocytosis and is an important virulence factor显示文摘 | Smith H E Damman M van der Velde J | 1999 | Infect Immun1999，67，： | 1 |
| 15 | Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative recta- analysis显示文摘 | Matsushita K van der Velde M Astor BC | 2010 | Lancet2010，375，9731： | 1 |
| 16 | Association of estimated glomerular filtration rate and albuminuria with all cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis显示文摘 | Matsushita K van der Velde M Astor B C | 2010 | Lancet2010，375，9731： | 1 |
| 17 | Diagnosis of near - fatal pulmonary embolus - in - transit with focused eehoear- diography显示文摘 | Fischer Jl Huis in't Veld MA Orland M | 2013 | J Emerg Med2013，45，2： | 1 |
| 18 | Recombinant factor Ⅶa should be used in massive obstetric haemorrhage 显示文摘 | Van de Velde M | 2007 | Int J Obstet Anesth2007，16，4： | 1 |
| 19 | Psychological contract breach and job attitudes:A meta-analysis of age as a moderator 显示文摘 | Bal P M De Lange A H Jansen P G W Der Velde M E G V | 2008 | Journal of Vocational Behavior2008，72，1： | 1 |
| 20 | Influ- ence of age,comorbidity and performance status on the choice of treatment for patients with non- small cell lung cancer : re- sults of a population- based study 显示文摘 | De RIJKE J M SCHOUTEN L J Ten VELDE G P | 2004 | Lung Cancer2004，46，2： | 1 |
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