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| 1 | Autoimmunity in acute ischemic stroke and the role of bloodbrain barrier: the dark side or the light one?显示文摘This article presents a synopsis of the current data on the mechanisms of blood-brain barrier (BBB) alteration and autoimmune response in acute ischemic stroke. Most researchers confirm the relationship between the severity of immunobiochemical changes and clinical outcome of acute ischemic stroke. Ischemic stroke is accompanied by aseptic inflammation, which alters the brain tissue and exposes the co-stimulatory molecules of the immune system and the neuronal antigens. To date, BBB is not considered the border between the immune system and central nervous system, and the local immune subsystems are found within and behind the BBB. BBB disruption contributes to the leakage of brain autoantigens and induction of secondary autoimmune response to neuronal antigens and long-term inflammation. Glymphatic system function is altered and jeopardized both in hemorrhagic and ischemic stroke types. The receptors of innate immunity (toll-like receptor-2 and toll-like receptor-4) are also involved in acute ischemia-reperfusion injury. Immune response is related to the key processes of blood clotting and fibrinolysis. At the same time, the stroke-induced immune activation may promote reparation phenomena in the brain. Subsequent research on the reduction of the acute ischemic brain injury through the target regulation of the immune response is promising. | Nikolay V. Tsygan Alexandr P. Trashkov Igor V. Litvinenko Viktoriya A. Yakovleva Alexandr V. Ryabtsev Andrey G. Vasiliev Leonid P. Churilov | 2019 | Frontiers of Medicine2019，13，4： | 7 |
| 2 | Iterative Bayesian Monte Carlo for nuclear data evaluation显示文摘In this work,we explore the use of an iterative Bayesian Monte Carlo(iBMC)method for nuclear data evaluation within a TALYS Evaluated Nuclear Data Library(TENDL)framework.The goal is to probe the model and parameter space of the TALYS code system to find the optimal model and parameter sets that reproduces selected experimental data.The method involves the simultaneous variation of many nuclear reaction models as well as their parameters included in the TALYS code.The‘best’model set with its parameter set was obtained by comparing model calculations with selected experimental data.Three experimental data types were used:(1)reaction cross sections,(2)residual production cross sections,and(3)the elastic angular distributions.To improve our fit to experimental data,we update our‘best’parameter set—the file that maximizes the likelihood function—in an iterative fashion.Convergence was determined by monitoring the evolution of the maximum likelihood estimate(MLE)values and was considered reached when the relative change in the MLE for the last two iterations was within 5%.Once the final‘best’file is identified,we infer parameter uncertainties and covariance information to this file by varying model parameters around this file.In this way,we ensured that the parameter distributions are centered on our evaluation.The proposed method was applied to the evaluation of p+^(59)Co between 1 and 100 MeV.Finally,the adjusted files were compared with experimental data from the EXFOR database as well as with evaluations from the TENDL-2019,JENDL/He-2007 and JENDL-4.0/HE nuclear data libraries. | Erwin Alhassan Dimitri Rochman Alexander Vasiliev Mathieu Hursin Arjan JKoning Hakim Ferroukhi | 2022 | Nuclear Science and Techniques2022，33，4： | 3 |
| 3 | Widely tunable 2.3μm III-V-on-silicon Vernier lasers for broadband spectroscopic sensing显示文摘Heterogeneously integrating III-V materials on silicon photonic integrated circuits has emerged as a promising approach to make advanced laser sources for optical communication and sensing applications. Tunable semiconductor lasers operating in the 2–2.5 μm range are of great interest for industrial and medical applications since many gases(e.g., CO_2, CO, CH_4) and biomolecules(such as blood glucose) have strong absorption features in this wavelength region. The development of integrated tunable laser sources in this wavelength range enables low-cost and miniature spectroscopic sensors. Here we report heterogeneously integrated widely tunable III-V-on-silicon Vernier lasers using two silicon microring resonators as the wavelength tuning components. The laser has a wavelength tuning range of more than 40 nm near 2.35 μm. By combining two lasers with different distributed Bragg reflectors, a tuning range of more than 70 nm is achieved. Over the whole tuning range, the side-mode suppression ratio is higher than 35 dB. As a proof-of-principle, this III-V-on-silicon Vernier laser is used to measure the absorption lines of CO. The measurement results match very well with the high-resolution transmission molecular absorption(HITRAN) database and indicate that this laser is suitable for broadband spectroscopy. | RUIJUN WANG STEPHAN SPRENGEL ANTON VASILIEV GERHARD BOEHM JORIS VAN CAMPENHOUT GuY LEPAGE PETER VERHEYEN ROEL BAETS MARKUS-CHRISTIAN AMANN GUNTHER ROELKENS | 2018 | Photonics Research2018，6，9： | 3 |
| 4 | Heat Storage Device for Pre-heating Internal Combustion Engines at Start-up显示文摘 | L L Vasiliev A G Burak A G Kulakov D A Miskinis P V Bohan | 1999 | Int J Therm Sci1999，，38： | 2 |
| 5 | Structural and functional properties of Yersinia pestis Cafl capsular antigen and their possible role in fulminant development of primary pneumonic plague显示文摘 | Abramov VM Vasiliev AM Khlebnikov VS | 2002 | J Proteome Res2002，1，： | 1 |
| 6 | Incorporation of fluorine ions into hydroxyapatite by a pH cycling method 显示文摘 | Qu H Vasiliev A L Aindow M | 2005 | J Mater Sci: Mater Med2005，16，5： | 1 |
| 7 | Polymorphism in the Laves-phase precipitates of a quinternary Nb-Mo-Cr-A1-Si alloy显示文摘 | Hu Y L Vasiliev A Zhang L C | 2009 | Scr Mater2009，60，： | 1 |
| 8 | A 3-D Monte-Carlo (Potts) model for recrystallization and grain growth in polycrystalline materials 显示文摘 | Ivasishin O M Shevchenko S V Vasiliev N L | 2006 | Materials Science and Engineering A2006，433，12： | 1 |
| 9 | 显示文摘 | Wei X Z Vasiliev A L Padture N P | 2005 | J Mater Res2005，20，： | 1 |
| 10 | Surface oxida- tion effects on the optical properties of silicon nanocrystals 显示文摘 | Vasiliev I Chelikowsky J R Martin R M | 2002 | Physical Review2002，65，12： | 1 |
| 11 | Cardioprotective effects of trimetazidine and a combination of succinic and malic acids in acute myocardial ischemia显示文摘 | Khazanov VA Kiseliova AA Vasiliev KY | 2008 | Bull Exp Biol Med2008，146，2： | 1 |
| 12 | Single-wall carbon nanotubes at ceramic grain boundaries显示文摘 | Vasiliev A L Poyato R Padture N P | 2007 | Scripta Materialia2007，56，6： | 1 |
| 13 | Improved interracial mechanical properties of Al2O3-13% TiO2 plasma-sprayed coatings derived from nanocrystalline powders显示文摘 | Bansal P Padture N P Vasiliev A | 2003 | Acta Materialia2003，51，1011： | 1 |
| 14 | Waste heat driven solid sorption coolers containing heat pipes for thermo control显示文摘 | Vasiliev L L Kanonchik L E Antuh A A | 1995 | Adsorption1995，1，4： | 1 |
| 15 | Effect of inter- nal radiation on the solid-liquid interface shape in low and high thermal gradient Czochralski oxide growth显示文摘 | Budenkova O Vasiliev M Yuferev V | 2007 | J Cryst Growth2007，303，1： | 1 |
| 16 | Loop heat pipe for cooling of high-power electronic components显示文摘 | Vasiliev L Lossouarn D Romestant C | 2009 | International Journal of Heat and Mass Transfer2009，52，12： | 1 |
| 17 | Influence of temperature and concentration on the sintering behavior and mechanical properties of hydroxyapatite 显示文摘 | Kothapalli C Wei M Vasiliev A | 2004 | Acta Materialia2004，52，19： | 1 |
| 18 | Anisogrid composite lattice structures development and aerospace applications显示文摘 | Vasiliev V V Barynin V A Razin A F | 2012 | Composite Structures2012，94，3： | 1 |
| 19 | lnvestigation of wear particles generated in human knee joints using atomic force microscopy显示文摘 | Wang M Peng Z Vasiliev K | 2013 | TribologyLetters2013，5，1： | 1 |
| 20 | New Generation of Filament-wound Composite Pressure Vessels for Commercial Applications显示文摘 | Vasiliev V V Krikanov A A Razin A F | 2003 | Composite Structure2003，62，： | 1 |
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