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| 1 | Micro RNAs as lung cancer biomarkers显示文摘Lung cancer is the leading cause of cancer mortality worldwide. Its high mortality is due to the poor prognosis of the disease caused by a late disease presentation, tumor heterogeneities within histological subtypes, and the relatively limited understanding of tumor biology. Importantly, lung cancer histological subgroups respond differently to some chemotherapeutic substances and side effects of some therapies appear to vary between subgroups. Biomarkers able to stratify for the subtype of lung cancer, prognosticate the course of disease, or predict the response to treatment are in high demand. In the last decade, microR NAs(miR NAs), measured in resected tumor samples or in fine needle aspirate samples have emerged as biomarkers for tumor diagnosis, prognosis and prediction of response to treatment, due to the ease of their detection and in their extreme specificity. Moreover, miR NAs present in sputum, in plasma, in serum or in whole blood have increasingly been explored in the last five years as less invasive biomarkers for the early detection of cancers. In this review we cover the increasing amounts of datathat have accumulated in the last ten years on the use of miR NAs as lung cancer biomarkers. | Valerio Del Vescovo Margherita Grasso Mattia Barbareschi Michela A Denti | 2014 | World Journal of Clinical Oncology2014，5，4： | 11 |
| 2 | Preparation and Characterization of Flexible, Transparent and Thermally Stable Aromatic Co-polyamides显示文摘Two aromatic co-polyamides were synthesized combining two diacid monomers containing bulky pendant groups, 5-(9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximido)isophthalic acid(DEAIA) and 5-tert-butylisophthalic acid(TERT), with 4,4′-(hexafluoroisopropylidene)dianiline(HFA) or 2,3,5,6-tetramethyl-1,4-phenylenediamine(Durene) by direct polycondensation. The structures of the obtained aromatic co-polyamides were confirmed by FTIR, Raman and 1 H-NMR. The co-copolyamide films, DHTH and DDTD, exhibited rms-roughness values between 0.94 and 1.60 nm, respectively. Moreover, they presented good thermal stability up to300 °C. Young's moduli of the co-polyamide films were between 4.1 and 4.3 GPa. X-ray diffraction results showed that the co-polyamide films were amorphous due to the incorporation of both bulky pendant groups, tert-butyl and dibenzobarrelene. The combination of bulky pendant groups provided intrinsically transparent co-polyamide films with a transmittance higher than 88% in the range of 400-780 nm.Due to these outstanding film and optical properties, they are suggested to be flexible substrates in applications for solar cell and other portable electronic devices. | José Antonio Tec-Sánchez Andrés Iván Oliva Arias Manuel Aguilar-Vega Juan Valerio Cauich-Rodríguez José Luis Santiago-García | 2019 | Chinese Journal of Polymer Science2019，37，2： | 3 |
| 3 | Double-layer graphene for enhanced tunable infrared plasmonics显示文摘Graphene is emerging as a promising material for photonic applications owing to its unique optoelectronic properties.Graphene supports tunable,long-lived and extremely confined plasmons that have great potential for applications such as biosensing and optical communications.However,in order to excite plasmonic resonances in graphene,this material requires a high doping level,which is challenging to achieve without degrading carrier mobility and stability.Here,we demonstrate that the infrared plasmonic response of a graphene multilayer stack is analogous to that of a highly doped single layer of graphene,preserving mobility and supporting plasmonic resonances with higher oscillator strength than previously explored single-layer devices.Particularly,we find that the optically equivalent carrier density in multilayer graphene is larger than the sum of those in the individual layers.Furthermore,electrostatic biasing in multilayer graphene is enhanced with respect to single layer due to the redistribution of carriers over different layers,thus extending the spectral tuning range of the plasmonic structure.The superior effective doping and improved tunability of multilayer graphene stacks should enable a plethora of future infrared plasmonic devices with high optical performance and wide tunability. | Daniel Rodrigo Andreas Tittl Odeta Limaj F Javier García de Abajo Valerio Pruneri Hatice Altug | 2017 | Light(Science & Applications)2017，6，1： | 3 |
| 4 | Purification and characterization of novel antifungal compounds from the sourdough Lactobacillu plantarum strain 21B 显示文摘 | Lavermicocca P Valerio F Evidente A | 2000 | Applied and Environmental Microbiology2000，66，9： | 1 |
| 5 | TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents 显示文摘 | Valerio A Cardile A Cozzi V | 2006 | J Clin Invest2006，116，10： | 1 |
| 6 | Single Chain Ig/Gamma Gene-Redirected Human T lymphocytes Produce Cytokines, Specifically Lyse Tumor CeLls, and Recycle Lytic Capacity 显示文摘 | Weijtens M E Willemsen R A Valerio D | 1996 | J Immunol1996，157，2： | 1 |
| 7 | Low platinum loading electrodes for polymer electrolyte fuel cells fabricated using thermoplastic ionomers 显示文摘 | Wilson M S Valerio J A Gottesfeld S | 1995 | Eleetroehim Aeta1995，40，3： | 1 |
| 8 | An LP - based approach to a two -stage cutting stock problem 显示文摘 | VALERIO de CARVALHO J M GUIMARAES RODRIGUES A J | 1995 | European Journal of Operational Research1995，84，： | 1 |
| 9 | Purification and Characterization of Novel AntifungalCompounds from the Sourdough Lactobacillus plantarum Strain 21B 显示文摘 | Lavermicocca P Valerio F Evidente A | 2000 | Applied and Environmental Microbiology2000，66，9： | 1 |
| 10 | Influence of morphology on in vitro compatibility of bioactive glasses显示文摘 | ANDRADE A VALERIO P GOES A M | 2006 | J Non-Cryst Solids2006，352，： | 1 |
| 11 | Antifungal activity of phenyllactic acid against molds isolated from bakery products显示文摘 | Lavermicocca P Valerio F Visconti A | 2003 | Applied and Environmental Microbiology2003，69，1： | 1 |
| 12 | Antifungal activity of phenyllactic acid against molds isolated from bakery products 显示文摘 | Lavermicocca P Valerio F Visconti A | 2003 | Appl Environ Microbiol2003，69，1： | 1 |
| 13 | PEMFC reconfigured anodes for enhancing CO tolerance with air bleed显示文摘 | Uribe F A Valerio J A Gavzon F H | 2004 | Electrochemical and Solid-State Letters2004，7，10： | 1 |
| 14 | Antifungal activity of phenyllactic acid against molds isolated from bakery products 显示文摘 | Lavermicocca P Valerio F Visconti A | 2003 | Appl Environ Microbio12003，69，： | 1 |
| 15 | In vivo voltammetry:from wire to wireless measurements显示文摘 | Crespi F Dalessandro D Valerio A L | 2004 | Journal of Neuroscience Methods2004，，140： | 1 |
| 16 | Purification and characterization of novel antifungal conlpounds from the sourdough Lactobacillus plantarum strain 21B 显示文摘 | Lavermicocca P Valerio F Evidente A | 2000 | Appl Environ Microbiol2000，66，： | 1 |
| 17 | The water content dependence of electro-osmotic drag in proton-conducting polymer electrolytes显示文摘 | Awodzinski T A Davey J Valerio J | 1995 | Electrochimica Acta1995，40，3： | 1 |
| 18 | Purification and characterization of novel antifungal compounds from the sourdough Lactobacillus plantarum Strain 21B显示文摘 | LAVERMICOCCA P VALERIO F EVIDENTE A | 2000 | Applied and Environmental Microbiology2000，66，9： | 1 |
| 19 | The water content dependence of electro-osmotic drag in proton-conducting polymer electrolytes 显示文摘 | Zawodainski T A Davey J Valerio J | 1995 | Electrochemical Acta1995，40，3： | 1 |
| 20 | TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents 显示文摘 | Valerio A Cardile A Cozzi V | 2006 | J Clin Invest2006，116，10： | 1 |
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