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| 1 | Effect of liver regeneration after partial hepatectomy and ischemia-reperfusion on expression of growth factor receptors显示文摘瞄准:在肝新生在四不同生长因素受体的表示的时间功课上调查试验性的部分肝切除术和 normothermic ischemia-reperfusion 损坏的效果。这由于在刺激肝新生的生长因素的潜在的治疗学的使用是相关的。方法:为部分肝切除术(PH ) , 80% 肝质量是在 Sprague Dawley 老鼠的 resected。局部缺血和灌注(I/R ) 被门静脉和肝的动脉的吸藏为 15 min 导致。表皮的生长因素受体,肝的生长因素受体,成纤维细胞生长因素受体和瘤坏死因素 receptor-1 被免疫组织化学在损害以后分析直到 72 h。量的 RT-PCR 在最小的受体表示(24 h ) 的时间点被执行。结果:在免疫组织化学, EGFR, HGFR, FGFR 和 TNFR1 与一座山峰在部分肝切除术以后给双性人看了局面的动力学直到 12 h,在 24 h 以后的一个天底和另一弱增加直到 72 h。在肝新生期间,在局部缺血和灌注以后,受体表示更低;在在灌注以后的 24 h 的天底是一样。评估这个天底是否被 mRNA 抄写的缺乏引起,或由于一根柱子翻译规定, RT-PCR 在 24 h 并且与放松肝相比被执行。在每根探针,为受体有特定的 mRNA。EGFR, FGFR 和 TNFR1 mRNA 表示比在放松肝相等或低,在 I/R 以后的 HGFR 表示比在控制强壮。结论:部分至少由于 post-transcriptional 处理,在分析受体的表达式有一个天底在肝损伤以后的 24 h。因此,到在损坏以后的 stimulate 肝新生 24 h 的生长因素的治疗学的使用可能不是成功的。 | P Baier G Wolf-Vorbeck S Hempel UT Hopt E von Dobschuetz | 2006 | World Journal of Gastroenterology2006，12，24： | 8 |
| 2 | Remote sensing and geographic information systems in the spatial temporal dynamics modeling of infectious diseases显示文摘Similar to species immigration or exotic species invasion,infectious disease transmis-sion is strengthened due to the globalization of human activities. Using schistosomiasis as an exam-ple,we propose a conceptual model simulating the spatio-temporal dynamics of infectious diseases. We base the model on the knowledge of the interrelationship among the source,media,and the hosts of the disease. With the endemics data of schistosomiasis in Xichang,China,we demonstrate that the conceptual model is feasible; we introduce how remote sensing and geographic information systems techniques can be used in support of spatio-temporal modeling; we compare the different effects caused to the entire population when selecting different groups of people for schistosomiasis control. Our work illustrates the importance of such a modeling tool in supporting spatial decisions. Our mod-eling method can be directly applied to such infectious diseases as the plague,lyme disease,and hemorrhagic fever with renal syndrome. The application of remote sensing and geographic informa-tion systems can shed light on the modeling of other infectious disease and invasive species studies. | GONG Peng 1,XU Bing 2 & LIANG Song 1、3 1. State Key Laboratory of Remote Sensing Science,Jointly Sponsored by the Institute of Remote Sensing Applications,Chi-nese Academy of Sciences and Beijing Normal University,Box 9718,Beijing 100101,China 2. Department of Geography,University of Utah,Salt Lake City,UT 84112,USA 3. School of Public Health,University of California,Berkeley,CA 94720,USA | 2006 | Science China(Life Sciences)2006，49，6： | 5 |
| 3 | Measurement of EBV‐IgG anti‐VCA avidity aids the early and reliable diagnosis of primary EBV infection显示文摘 | PeterRobertson SandyBeynon RossWhybin CatherineBrennan UtéVollmer‐Conna IanHickie AndrewLloyd | 2003 | J Med Virol2003，，4： | 2 |
| 4 | Malar implants for improvement of the facial appearance显示文摘 | Hinderer UT | 1975 | Plast Reconstr Surg1975，56，2： | 1 |
| 5 | Efficacy and tolerability of lornoxicam versus tramadol in postoperative pain 显示文摘 | Ovesen J Larsen UT | 1999 | J Clin Pharmacol1999，39，8： | 1 |
| 6 | Outcome of persistent vegetative state following hypoxic or traumatic brain injury in children and adolescents显示文摘 | LAUB MC | 1996 | Neuropediatric1996，27，2： | 1 |
| 7 | Hypoxia is a major stimulator of osteoclast formation and bone resorption显示文摘 | Arnett TR Gibbons DC Utting JC | 2003 | J Cell Physiol2003，196，1： | 1 |
| 8 | Myocardial velocity gradient assessed by a tissue Doppler imaging technique显示文摘 | Masaun UT Kunio MA | 1999 | Echocordiography1999，16，5： | 1 |
| 9 | Lysosomal involvement in apoptosis显示文摘 | Brunk UT Neuzil J Eaton JW | 2001 | Redox Rep2001，6，2： | 1 |
| 10 | Protein- and mRNA-based phenotype-genolype correlations in DMD/BMD with pointmutations and molecular basis for HMD with nonsense andframeshift mutations in the DMD gene显示文摘 | Oeburgravc N Daoud F Llense S ut al | 2007 | Hum Mutat2007，28，2： | 1 |
| 11 | Autophagy in cardiac myocyte homeostasis, aging, and pathology 显示文摘 | Terman A Brunk UT | 2005 | Cardiovasc Res2005，68，3： | 1 |
| 12 | New pocket echocardiography device is interchangeable with high-end portable system when performed by experienced examiners 显示文摘 | Frederiksen CA Juhl-Olsen P Larsen UT | 2010 | Acta Anaesthesiol Scand2010，54，10： | 1 |
| 13 | Hypoxia is a majorstimulator of osteoclast formation and bone resorption显示文摘 | Arnett TR Gibbon DC Utting JCe t al | | J Cell Physiol0，3196，1： | 1 |
| 14 | Current development of cardic imaging with multidetector-row CT显示文摘 | Becker CR Ohnesorge BM Schoepf UT | 2000 | EJR2000，36，2： | 1 |
| 15 | Microsatellite analysis of free tumor DNA in urine, serum, and plasma of patients: a minimally invasive method for the detection of bladder cancer显示文摘 | Utting M Werner W Dahse R | 2002 | Clin Cancer Res2002，8，1： | 1 |
| 16 | Cemid/lipofuscin formation in cultured human fibroblasts: the role of oxidative stress and lysosomal proteolysis 显示文摘 | Tennan A Brunk UT | 1998 | Mech Aging Dev1998，104，3： | 1 |
| 17 | Orientation tuning and receptive field structure in cat striate neurons during local blockade of intracortical inhibition 显示文摘 | Eysel UT Shevelev IA Lazareva NA | 1998 | Neuroscience1998，84，1： | 1 |
| 18 | The relevance of anxiety, depression,and coping in patients after liver transplanta- tion显示文摘 | Nickel R Wunsch A Egle UT | 2002 | Liver Transpl2002，8，1： | 1 |
| 19 | Electrochemical kinetics of the high entropy alloys in aqueous environments--a comparison with type304 stainless steel 显示文摘 | Chen YY Hong UT Shih HC | 2005 | Corrosion Science2005，47，11： | 1 |
| 20 | Autophagy and aging: the importance of maintaining ' clean' cells 显示文摘 | Cuervo AM Bergamini E Brunk UT | 2005 | Autophagy2005，1，3： | 1 |
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