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| 1 | Immune response to an indigenously developed r-Hepatitis B vaccine in mixed population: Study of an accelerated vaccination schedule显示文摘AIM: To establish the safety and efficacy of an indigenously developed r-hepatitis B vaccine using an accelerated schedule and to highlight the social awareness and commitment in preventing the spreading of hepatitis B virus infection.METHODS: The study was a multicentric, double blind,randomized (3:1) study using three doses of vaccine immunization schedule (20 μg for those above 10 years old and 10 μg for those below 10 years old) on d 0, 30and 60. One hundred and sixty-six subjects were enrolled(87 males and 76 females aged 5-35 years). The main outcome measure was assessment of immunogenicity and safety.RESULTS: A 100% seroconversion response was observed on the 30th d after the 1st injection in both the experimental groups. The sero-protection data reported a 41.2-65.6% response on the 30th d after the 1st injection and reached 100% on the 60th d. Descriptive statical analysis showed a geometric mean titer value of 13.77 mIU/mL in the test (BEVAC) group and 10.95 mIU/mL in the commercial control (ENGERIX-B) group on the 30th d after the 1st injection. The response on the 60th d showed a geometric mean titre value (GMT) of 519.84 mIU/mL in the BEVAC group and 475.46 mIU/mL in the ENGERIX-B group. On the 90th d, the antibody titer response was observed to be 2627.58 mIU/mL in the BEVAC group and 2272.72 mIU/mL in the ENGERIX-B group. Two subjects in each group experienced pains at injection site after the first vaccination. A total of six subjects in both groups experienced a solicited adverse reaction, which included pains, swelling and redness at the injection site, three subjects in the group-B had a pain at the injection site after the third dose. No other serious adverse events occurred and no dose-related local or general symptoms were observed during the study.CONCLUSION: The vaccine is safe, efficacious and immunogenic in comparison with the well documented ENGERIX-B. | A Chowdhury A Santra CM Habibullah AA Khan J Karunakaramaiah TSA Kishore AVR Raju S Lahiri | 2005 | World Journal of Gastroenterology2005，11，7： | 12 |
| 2 | Efficient Certificateless Aggregate Signature Scheme显示文摘In ubiquitous computing, data should be able to be accessed from any location, and the correctness of data becomes vital during the communication. Suppose that many users sign different messages respectively, before forwarding or sending these messages, then the verifier must spend a lot of computing time to verify their signatures. Consequently, the aggregate signature scheme is an effective method of improving efficiency in this kind of systems, which provides the convenience for the verifier. In this paper, we propose a new certificateless aggregate signature scheme which is efficient in generating a signature and verification. This scheme is provably secure under the extended computational Diffie-Hellman assumption. | Yu-Chi Chen Gwoboa Homg Chao-Liang Liu Yuan-Yu Tsa Chi-Shiang Chan | 2012 | Journal of Electronic Science and Technology2012，10，3： | 2 |
| 3 | Predictive factors of gefitinib antitumor in East Asian advanced non-small cell lung cancer patient显示文摘 | CHANG GC TSA I CM CHEN KC | 2006 | J Thorac Oncol2006，1，6： | 1 |
| 4 | Resuscitation fromhemorrhagic shock with Hydroxyethyl Starch and coagulation changes 显示文摘 | Cabrales P Tsa AG Intalieglietta M | 2007 | Shock2007，28，4： | 1 |
| 5 | Modified eddy viscosity model in fully devel- oped asymmetric channel flows显示文摘 | Tsa W Ettema R | 1994 | Journal of Engineering Me- chanics1994，120，4： | 1 |
| 6 | Model integration using SML 显示文摘 | Tsa Y C | 1998 | Decision Support Systems (S0167-9236)1998，22，4： | 1 |
| 7 | Low cost removal of disperse dye from aqueous solution using palm ash显示文摘 | TSA M Hasnain LANG Lee Siew ASAARI Faridah A H | 2007 | Dyes and Pigments2007，74，： | 1 |
| 8 | Using Fuzzy Signal Detection Theory to Determine Why Experienced and Trained Drivers Respond Faster Than Novices in A Hazard Perception Test 显示文摘 | Wallis TSA Horswill MS | 2007 | Accident Analysis & Prevention2007，39，6： | 1 |
| 9 | Effect of cordycepin on Hantaan virus 76 - 118 infection of primary human em- bryonic pulmonary fibroblasts - characterization of apop- totic effects 显示文摘 | Xu F L Lee Y L Tsa W Y | 2005 | Acta Virol2005，49，3： | 1 |
| 10 | Generalized predictive control using recurrent fuzzy neural networks for industrial process 显示文摘 | LU C H TSA I C C | 2007 | Journal of Process Control2007，17，1： | 1 |
| 11 | Application of real-time PCR, DGGE fingerprinting and culture-based method to evaluate the effectiveness of intrinsic bioremediation on the control of petroleum-hydrocarbon plume 显示文摘 | KAO C M CHEN C S TSA F Y | 2010 | Journal of Hazardous Materials2010，178，13： | 1 |
| 12 | Fast pyrolysis of rice straw,sug-arcane bagasse and coconut shell in an induction2heating reactor显示文摘 | TSA I W T LEE M K CHANG Y M | 2006 | Journal of Analytical and App lied Pyrolysis2006，76，12： | 1 |
| 13 | Posterior continuous curvilinear capsulorhexis;an experimental study with clinical ap- plications 显示文摘 | Castaneda VE Legler UFC Tsa JC | 2012 | Ophthalmology2012，99，： | 1 |
| 14 | Digital Image Watermarking Using Discrete Wavelet Transform and Singular Value De- composition显示文摘 | Lai Chih-Chin Tsa Cheng-Chih | 2010 | IEEE Transactions on Instrumentaion and Measurement2010，，30： | 1 |
| 15 | Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways显示文摘 | Huang W W Ko S W Tsa H Y | 2011 | Int J Oncology2011，38，4： | 1 |
| 16 | Celm:aliza- tion and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles显示文摘 | AUGUSTINACK JC SANDERS JL TSA | 2002 | J Neuropathol Exp Neurol2002，6，6： | 1 |
| 17 | Advanced trauma life support,8th editon,the evidence for change显示文摘 | Kortbeek JB Al TSA Ali J | 2008 | J Trauma2008，64，6： | 1 |
| 18 | Effect of TiO2 nanoparticles on the electropolymerization of polypyrrole显示文摘 | Liu Y C Huang J M Tsa C E | 2004 | Chem Phys Lett2004，387，： | 1 |
| 19 | Current status of ground source heat pumps and underground thermal energy storage in Europe显示文摘 | Sanner B Kary tsas C M endrinos D Rybach L | 2003 | Geothermies2003，3，2： | 1 |
| 20 | Trauma-hemorrhage activates signal transduction pathways in mouse splenic T cells显示文摘 | Samy TSA Ayala A Catania RA | 1998 | Shock1998，9，6： | 1 |
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