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| 1 | Coarctation of the aorta:Management from infancy to adulthood显示文摘Coarctation of the aorta is a relatively common form of congenital heart disease, with an estimated incidence of approximately 3 cases per 10000 births. Coarctation is a heterogeneous lesion which may present across all age ranges, with varying clinical symptoms, in isolation, or in association with other cardiac defects. The first surgical repair of aortic coarctation was described in 1944, and since that time, several other surgical techniques have been developed and modified. Additionally, transcatheter balloon angioplasty and endovascular stent placement offer less invasive approaches for the treatment of coarctation of the aorta for some patients. While overall morbidity and mortality rates are low for patients undergoing intervention for coarctation, both surgical and transcatheter interventions are not free from adverse outcomes. Therefore, patients must be followed closely over their lifetime for complications such as recoarctation, aortic aneurysm, persistent hypertension, and changes in any associated cardiac defects. Considerable effort has been expended investigating the utility and outcomes of various treatment approaches for aortic coarctation, which are heavily influenced by a patient's anatomy, size, age, and clinical course. Here we review indications for intervention, describe and compare surgical and transcatheter techniques for management of coarctation, and explore the associated outcomes in both children and adults. | Rachel D Torok Michael J Campbell Gregory A Fleming Kevin D Hill | 2015 | World Journal of Cardiology2015,7,11: | 27 |
| 2 | Clinical significance of lymphadenectomy in patients with gastric cancer显示文摘Approximately thirty percent of patients with gastric cancer undergo an avoidable lymph node dissection with a higher rate of postoperative complication. Comparing the D1 and D2 dissections,it was found that there is a significant difference in morbidity,favoured D1 dissection without any difference in overall survival. Subgroup analysis of patients with T3 tumor shows a survival difference favoring D2 lymphadenectomy,and there is a better gastric cancer-related death and non-statistically significant improvement of survival for node-positive disease in patients with D2 dissection. However,the extended lymphadenectomy could improve stage-specific survival owing to the stage migration phenomenon. The deployment of centralization and application of national guidelines could improve the surgical outcomes. The Japanese and European guidelines enclose the D2 lymphadenectomy as the gold standard in R0 resection. In the individualized,stageadapted gastric cancer surgery the Maruyama computer program(MCP) can estimate lymph node involvement preoperatively with high accuracy and in addition the Maruyama Index less than 5 has a better impact on survival,than D-level guided surgery. For these reasons,the preoperative application of MCP is recommended routinely,with an aim to perform 'low Maruyama Index surgery'. The sentinel lymph node biopsy(SNB) may decrease the number of redundant lymphadenectomy intraoperatively with a high detection rate(93.7%) and an accuracy of 92%. More accurate stage-adapted surgery could be performed using the MCP and SNB in parallel fashion in gastric cancer. | dezso tóth jános plósz miklós torok | 2016 | World Journal of Gastrointestinal Oncology2016,8,2: | 8 |
| 3 | Ternary Ni-Co-Fe oxyhydroxide oxygen evolution catalysts:Intrinsic activity trends,electrical conductivity,and electronic band structure显示文摘Nickel-,cobalt-,and iron-based(oxy)hydroxides comprise the most-commonly studied electrocatalysts for the oxygen-evolution reaction(OER)in alkaline solution.A fundamental understanding of composition-structure-activity relationships for mixed-metal Ni-Co and Ni-Co-Fe(oxy)hydroxides is important to guide the design of advanced OER catalysts.Here we use cyclic voltammetry,chronopotentiometry,inductively-coupled plasma-optical emission spectroscopy,and in situ electrical conductivity measurements to characterize the properties and activity of various compositions of Ni-Co-Fe(oxy)hydroxides prepared by cathodic co-electrodeposition.Consistent with previous studies,we find Fe is essential for the mixed-metal(oxy)hydroxides to achieve high OER activity.In the rigorous absence of Fe(achieved by using specially cleaned electrolytes),the most-active Ni-Co(oxy)hydroxide composition has an OER turn-over frequency only twice that ofpure Co(oxy)hydroxide,suggesting minimal synergism between the two metals.The addition of Co to Ni-Fe(oxy)hydroxides shifts the onset of electrical conductivity to lower potentials,but has little effect on the intrinsic OER activity,with the most-active Ni-Co-Fe(oxy)hydroxide having an OER turn-over frequency only -1.5 times that of the Ni-Fe(oxy)hydroxides.The magnitudes of the electrical conductivities are similar for all the compositions measured.Density-functional-theory-calculated projected density of states show a significant contribution of all chemical elements at the valence band edge of the mixed-metal oxyhydroxide electronic structure,demonstrating significant electronic hybridization between the elements.The calculations suggest the involvement of all the elements in modulating the electronic structure at putative Fe-based active sites that are probably located at edges or defects in the two-dimensional oxyhydroxide sheets. | Michaela Burke Stevens Lisa J. Enman Ester Hamal Korkus Jeremie Zaffran Christina D. M. Trang James Asbury Matthew G. Kast Maytal Caspary Toroker Shannon W. Boettcher | 2019 | Nano Research2019,12,9: | 5 |
| 4 | Comparison of different lymph node staging systems in prognosis of gastric cancer:a bi-institutional study from Hungary显示文摘Objective: The Union for International Cancer Control(UICC) Node(N) classification is the most common used staging method for the prognosis of gastric cancer. It demands adequate, at least 16 lymph nodes(LNs) to be dissected; therefore different staging systems were invented.Methods: Between March 2005 and March 2010, 164 patients were evaluated at the Department of General Surgery in the Kenézy Gyula Hospital and at the Department of General, Thoracic and Vascular Surgery in the Kaposi Mór Hospital. The 6th, 7th and 8th UICC N-staging systems, the number of examined LNs, the number of harvested negative LNs, the metastatic lymph node ratio(MLR) and the log odds of positive LNs(LODDS) were determined to measure their 5-year survival rates and to compare them to each other.Results: The overall 5-year survival rate for all patients was 55.5% with a median overall survival time of 102 months. The tumor stage, gender, UICC N-stages, MLR and the LODDS were significant prognostic factors for the 5-year survival with univariate analysis. The 6th UICC N-stage did not follow the adequate risk in comparing N2 vs. N0 and N3 vs. N0 with multivariate investigation. Comparison of performances of the residual N classifications proved that the LODDS system was first in the prediction of prognosis during the evaluation of all patients and in cases with less than 16 harvested LNs. The MLR gave the best prognostic prediction when adequate(more than or equal to 16) lymphadenectomy was performed.Conclusions: We suggest the application of LODDS system routinely in western patients and the usage of MLR classification in cases with extended lymphadenectomy. | dezso tóth adrienn bíró zsolt varga miklós torok péterárkosy | 2017 | Chinese Journal of Cancer Research2017,29,4: | 4 |
| 5 | 显示文摘 | Péter Antal Torok Gabriella Tóth Géza | 1998 | Journal of Chromatography A1998,797,: | 2 |
| 6 | 显示文摘 | Péter Antal Torok Gabriella Armstrong Daniel W | 2000 | Journal of Chromatography A2000,904,: | 2 |
| 7 | Toll - like receptor (TLR)2 and 4 mutations in periodontal disease显示文摘 | FOLWACZNY M GLAS J TOROK H P | 2004 | Clin Exp Immunol2004,135,2: | 1 |
| 8 | The use of Gauss-Laguerre vector beams in STED microscopy显示文摘 | TOROK P MUNRO P R T | 2004 | Opt Express2004,12,15: | 1 |
| 9 | Myocardial injuries mediated by free oxygen radicals 显示文摘 | Torok B Roth E Matkovics B | 1986 | Acta Physiol Hung1986,68,1: | 1 |
| 10 | Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis显示文摘 | Torok HP Glas J Tonenchi L | 2004 | Clin Immunol2004,112,1: | 1 |
| 11 | Numerical solution of linear stochastic differential epuations显示文摘 | Torok C | 1994 | Computers and Mathematics with Applications1994,27,4: | 1 |
| 12 | Natural history of hydatidiform mole after primary evacuation显示文摘 | Lurain JR Brewer Jl Torok EE | 1983 | Am J Obstet Gyneeol1983,145,5: | 1 |
| 13 | The possible role of anaerobic bacteria in chronic prostatitis显示文摘 | Szoke I Torok L Dosa E et a1 | 1998 | Int J Androl1998,21,3: | 1 |
| 14 | Evaluation of the MODS CultureTechnique for the Diagnosis of Tuberculous Meningitis显示文摘 | Caws M Ha D Torok E et a1 | 2007 | PLOS 0NE2007,2,: | 1 |
| 15 | Comparative study in the Ames test of benzo pyrene and 2-aminoanthra- cene metabolic activation using rat hepatic $9 and hep- atocytes following in vivo or in vitro induction 显示文摘 | Jenmitz K Veres Z Torok G | 2004 | Mu- tagenesis2004,19,3: | 1 |
| 16 | Response to combination therapy with interferon aifa-2a and ribavirin in chronic hepatitis C according to a TNF-αpromoter polymorphism显示文摘 | Schiemann U Glas J Torok P | 2003 | Digestion2003,68,1: | 1 |
| 17 | Whole-genome sequencing for analysis of an outbreak of meticillin-resistant Staphylococcus aureus : a descriptive study显示文摘 | Harris SR Cartwright EJ Torok ME | 2013 | Lancet Infect Dis2013,13,2: | 1 |
| 18 | Functional cartilage MRI T2 mapping: evaluating the effeet of age and training on knee car- tilage response to running 显示文摘 | Mosher TJ Liu Y Torok CM | 2010 | Osteoarthritis Cartilage2010,18,3: | 1 |
| 19 | Grape marc reduc met- hane emissions when fed to dairy cows显示文摘 | Moate P J Williams S R O Torok V A | 2014 | Dairy Sci2014,97,: | 1 |
| 20 | High-performance liquid chromatographic separation of enantiomers of unusual amino acids on a teicoplanin chiral stationary phase 显示文摘 | Peter A Torok G Armstrong DW | 1998 | J Chromatogr A1998,793,2: | 1 |