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| 1 | Mitral peak early diastolic filling velocity to deceleration time ratio as a predictor of prognosis in patients with chronic heart failure and preserved or reduced ejection fraction显示文摘ObjectiveDoppler 导出僧帽形的山峰到减速时间比率(E/DT ) 的早心脏舒张的充满速度为在一般人口预言预后作为参数被建议了。这研究有希望地在就医的病人在临床的、常规 echocardiographic 和 mitral-Doppler 变量上调查 E/DT 的增长的预示的值因为患心脏代偿失调的心失败(HF ).MethodsWe 分析了 95 个 HF 病人(吝啬的年龄 64.8 ±12.2 年) 从 2010 年 1 月在我们的机构就医了到 2012 年 3 月。主要端点是心脏的死亡或住院,无论哪个首先发生了。考克斯回归分析被执行识别 outcomes.ResultsDuring 后续的重要预言者(中部 37.7 个月) 13 个病人死了, 44 为一个心脏的事件被就医。在 univariable 分析,纽约心协会(NYHA ) 功能的班, furosemide 剂量,侧面的有三尖的环形的飞机收缩旅行,减速时间和 E/DT 结果是预兆的。在 multivariable 分析, E/DT 是预后的唯一的预言者(危险比率 = 1.02, P = 0.018 ) ,把增长预示的信息给临床并且另外的 echocardio 图形的措施(从 15.4 ~ 25.2 的全球 chi 平方;P = 0.032 ).ConclusionsE/DT 在 HF 病人给独立、增长的预示的信息。 | Flora Pirozzi AntoneUa Paglia Laura Sasso Pasquale Abete Angelo Carlomagno Carlo G Tocchetti Domenico Bonaduce Mario Petretta | 2015 | Journal of Geriatric Cardiology2015，12，4： | 2 |
| 2 | Reversal of cardiac hy- pertrophy and fibrosis fi'om pressure overload by tetrahydrobiopterin: efficacy of reeoupling nitric oxide synthase as a therapeutic strategy 显示文摘 | Moans AL Takimoto E Tocchetti CG | 2008 | Circulation2008，117，20： | 1 |
| 3 | CCR5 inhibition prevents cardiac dysfunction in the SIV/Macaque model of HIV显示文摘 | Kelly K M Tocchetti C G Lyashkov A | 2014 | JAm Heart Assoc2014，3，00： | 1 |
| 4 | Oxidative and nitrosati- ve stress in the maintenance of myocardial function 显示文摘 | Zhang Y Tocchetti CG Krieg T | 2012 | Free Radic Biol Med2012，53，8： | 1 |
| 5 | PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin 1 phosphorylation显示文摘 | Lee DI Vahebi S Tocchetti CG | 2010 | Basic Res Cardiol2010，105，3： | 1 |
| 6 | Oxidative and nitrosative stress in the maintenance of myocardial function显示文摘 | Zhang Y Tocchetti CG Krieg T | 2012 | Free Radic Biol Med2012，53，： | 1 |
| 7 | Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies显示文摘 | Octavia Y Tocchetti C G Gabrielson K L | 2012 | Journal of Molecular and Cellular Cardiology2012，52，6： | 1 |
| 8 | Nitroxyl im- proves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2 + cycling显示文摘 | Tocchetti CG Wang W Froehlich JP | 2007 | Circ Res2007，100，1： | 1 |
| 9 | Doxorubicin - induced cardiomyopathy: from molecular mecha - nisms to therapeutic strategies 显示文摘 | Octavia Y Tocchetti CG Cabrielson KL | 2012 | J Mol Cellular Cardiol2012，52，6： | 1 |
| 10 | Assessment of in vitro-generated platelet microparticles using a modified flow cytometric strategy 显示文摘 | Tocchetti EV Flower RL Lloyd JV | 2001 | Thromb Res2001，103，1： | 1 |
| 11 | Doxorubicin-induced cardiomyopathy:from molecular mechanisms to therapeutic strategies 显示文摘 | OCTAVIA Y TOCCHETTI C G GABRIELSON K L | 2012 | J Mol Cell Cardiol2012，52，6： | 1 |
| 12 | Assessment of in vitro-generatod platelet microparticles using a modified flow cytometric strategy显示文摘 | Tocchetti E V Flower R L Loyd J V | 2001 | Thromb Res2001，103，： | 1 |
| 13 | Nitroxyl increases force development in rat cardiac muscle 显示文摘 | Dai T Tian Y Tocchetti CG | 2007 | J Physiol2007，580，3： | 1 |
| 14 | Assessment of in vitro-generated platelet microparrticles using a modified flow cytometric strategy显示文摘 | FLOWER RL LLOYD JV | 2001 | Thrombosis Research2001，103，： | 1 |
| 15 | Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling显示文摘 | Tocchetti CG Wang W Froehlich JP | 2007 | Circ Res2007，100，1： | 1 |
| 16 | Doxorubicin--in- duced cardiomyopathy: from molecular mechanisms to therapeutic strategies显示文摘 | Octavia Y Tocchetti CG Gabrielson KL | 2012 | J Mol Cellular Cardiol2012，52，6： | 1 |
| 17 | Assessment of in vit-ro-generated platelet microparticles using a modified flow cytometric strategy显示文摘 | Tocchetti EV Flower RL Lloyd JV | 2001 | Thromb Res2001，103，1： | 1 |
| 18 | Doxorubicin-induced cardiomyopa-thy:from molecular mechanisms to therapeutic strategies显示文摘 | Octavia Y Tocchetti CG Gabrielson KL Janssen S Crijns HJ Moens AL | 2012 | J Med Cell Cardiol2012，52，6： | 1 |
| 19 | Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge显示文摘 | Tocchetti CG1 Ragone G Coppola C | 2012 | Eur J Heart Fail2012，14，2： | 1 |
| 20 | Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric ox- ide synthase as a therapeutic strategy显示文摘 | Moens A L Takimoto E Tocchetti C G | 2008 | Circulation2008，117，20： | 1 |
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