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| 1 | XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks显示文摘 | Julie K Horton Mary Watson Donna F Stefanick Daniel T Shaughnessy Jack A Taylor Samuel H Wilson | 2008 | Cell Research2008,18,1: | 17 |
| 2 | Age distribution,polyps and rectal cancer in the Egyptian population-based cancer registry显示文摘AIM:To describe the clinical and epidemiologic profiles of the disease and to compare the findings with those generated from the previous hospital-based studies.METHODS:The Gharbiah cancer registry is the only population-based cancer registry in Egypt since 1998.We analyzed the data of all colorectal cancer patients included in the registry for the period of 1999-2007.All medical records of the 1364 patients diagnosed in Gharbiah during the study period were retrieved and the following information abstracted:age,residence,diagnosis date,grade,stage,topology,clinical characteristics,and histology variables.Egyptian census data for 1996 and 2006 were used to provide the general population's statistics on age,sex,residence and other related demographic factors.In addition to age-and sex-specific incidence rate analyses,we analyze the data to explore the incidence distribution by rural-urban differences among the 8 districts of the province.We also compared the incidence rates of Gharbiah to the rates of the Surveillance Epidemiology and End Results(SEER) data of the United States.RESULTS:Over the 9 year-period,1364 colorectal cancer cases were included.The disease incidence under age 40 years was relatively high(1.3/10 5) while the incidence in the age groups 40 and over was very low(12.0/10 5,19.4/10 5 and 21.2/10 5 in the age groups 40-59 years,60-69 years and > 70 years,respectively).The vast majority of tumors(97.2%) had no polyps and 37.2% of the patients presented with primary lesions in the rectum.Colorectal cancer was more common in patients from urban(55%) than rural(45%) areas.Regional differences in colon and rectal cancer incidence in the 8 districts of the study province may reflect different etiologic patterns in this population.The registry data of Egypt shows a slightly higher incidence of colorectal cancer than the United States in subjects under age 40 years.The results also shows significantly lower incidence of colorectal cancer in subjects over age 40 years compared to the same age group in the United States SEER.CONCLUSION:Low rate of polyps,low incidence in older subjects,and high rate of rectal cancer in Egypt.Future studies should explore clinical and molecular disease patterns. | Darlene Veruttipong Amr S Soliman Samuel F Gilbert Taylor S Blachley Ahmed Hablas Mohamed Ramadan Laura S Rozek Ibrahim A Seifeldin | 2012 | World Journal of Gastroenterology2012,18,30: | 12 |
| 3 | The role of the N-methyl-D-aspartate receptor in the proliferation of adult hippocampal neural stem and precursor cells显示文摘New neurons are continuously generated from resident pools of neural stem and precursor cells(NSPCs)in the adult brain.There are multiple pathways through which adult neurogenesis is regulated,and here we review the role of the N-methyl-D-aspartate receptor(NMDAR)in regulating the proliferation of NSPCs in the adult hippocampus.Hippocampal-dependent learning tasks,enriched environments,running,and activity-dependent synaptic plasticity,all potently up-regulate hippocampal NSPC proliferation.We first consider the requirement of the NMDAR in activity-dependent synaptic plasticity,and the role the induction of synaptic plasticity has in regulating NSPCs and newborn neurons.We address how specific NMDAR agonists and antagonists modulate proliferation,both in vivo and in vitro,and then review the evidence supporting the hypothesis that NMDARs are present on NSPCs.We believe it is important to understand the mechanisms underlying the activation of adult neurogenesis,given the potential that endogenous stem cell populations have for repopulating the hippocampus with functional new neurons.In conditions such as age-related memory decline,neurodegeneration and psychiatric disease,mature neurons are lost or become defective;as such,stimulating adult neurogenesis may provide a therapeutic strategy to overcome these conditions. | TAYLOR Chanel J HE RongQiao BARTLETT Perry F | 2014 | Science China(Life Sciences)2014,57,4: | 6 |
| 4 | 热浸镀锌超高强钢板钒微合金化技术研究显示文摘对超高强度钢板进行热处理,模拟热浸镀锌和合金化镀锌工艺的热循环,并考察获得的力学性能和微观组织。研究用钢含有适量的碳(~0.2%)、锰(1.2%)和铬(0.4%),保证钢板在奥氏体化后在镀锌前的连续退火线上进行快速冷却时能够完全转变成马氏体。采用不同的钒含量(0~0.1%)和氮含量(0.002%~0.012%),研究这些微合金化元素对回火马氏体强度的影响。尤其与高氮相配合情况下,钒有助于抵抗回火效应,因此在镀锌后大部分原始强化贡献被保留下来,使得钢的抗拉强度超过1 000 MPa。使用铝或硅进行不同脱氧试验,发现在同一碳含量下两者具有相同的强度水平,但是Si镇静钢的弯曲性能明显优异。对退火钢板进行微观组织观察,但是钒产生有益作用的原因还未完全掌握。通过研究得出这样结论:钒微合金化对耐腐蚀超高强度钢板的开发而言是一种极具前景的途径。 | Hutchinson B Martin D Karlsson O Lindberg F Thoors H Marceau R K W Taylor A S | 2016 | 钢铁钒钛2016,37,6: | 2 |
| 5 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017,25,5: | 2 |
| 6 | 日粮磷脂对大西洋鲑鱼早期发育和生长性能的影响显示文摘研究旨在证实大西洋鲑鱼对日粮磷脂的需求,更好地确定其需要水平和时期。因此,通过给大西洋鲑鱼提供磷虾或大豆卵磷脂探讨磷脂对其的影响。首先饲喂鱼苗含蛋白质55%和脂肪17%的饲粮,通过添加磷虾油或大豆磷脂补充脂肪.根据回归分析设计5个水平,分别为总磷脂1.5%(未添加)、2.6%、3.2%、3.6%和4.2%。在1g(受精后1400°dpf)、2.5g(1990°ape)、5g(2350°dpf)、10-20g(2850°dpf)和二龄鲑(3800°dpf)时进行取样。整体存活率高,说明存活率和饲粮磷脂添加水平呈正相关(r2=0.59—0.72)。磷脂促进了鱼苗的生长,且饲喂磷虾磷脂2.6%和大豆磷脂3.6%的鱼增长最快。鱼苗达到2.5g之前与之后生长模式不同,0-2.5g鱼补充磷虾磷脂2.6%和大豆磷脂3.6%后的生长速率(SGR)显著高于基础日粮(P〈0.05),而2.5g-二龄鲑期间,各处理之间没有差异。饲喂未补充磷脂的日粮,2.5g时发现鱼肠道脂肪变性,患病率达20%,饲喂低水平大豆磷脂日粮的鱼肠道脂肪变性患病率达10%,而喂食磷虾油和高水平大豆磷脂(≥3.2%)后以及在后期阶段,肠邋脂肪变性情况开始消失。在生命早期阶段,鲑鱼对日粮磷脂的要求是一致的。 | Taylor J F Martinez-Rubio L Pozo J D Walton J M Tinch A E Migaud H Tocher D R | 2015 | 饲料博览2015,0,8: | 2 |
| 7 | Gold on titania catalysts for the oxidation of carbon monoxide : Control of pH during preparation with various gold contents显示文摘 | MOREAU F BOND G C TAYLOR A O | 2005 | Journal of Catalysis2005,231,1: | 1 |
| 8 | Determination of wood density in standing white spruce using Pilodyn tester显示文摘 | MICKO M M WANG E I C TAYLOR F W | 1982 | The Forestry Chronicle1982,58,4: | 1 |
| 9 | Isolation of protein products from chromium containing leather waste using two consecutive enzymes and purification of final chromium product: pilot plant studies 显示文摘 | Brown E M Cabeza L F Taylor M M | 1999 | JSL TC1999,,83: | 1 |
| 10 | Crystal structures of some double hydroxide minerals 显示文摘 | Taylor H F W | 1973 | Mineralogical Magazine1973,39,304: | 1 |
| 11 | 显示文摘 | Rancourt J D Taylor L T | 1998 | JMS-Pure Appl Chem1998,35,4: | 1 |
| 12 | Fluorescent microsphere-based readout technology for multiplexed human single nueleotide polymorphism analysis and bacterial identification 显示文摘 | Ye F Li M S Taylor J D | 2001 | Hum Murat2001,17,4: | 1 |
| 13 | Active shape models: Their training and application 显示文摘 | Cootes T F Cooper D Taylor C J | 1995 | Computer Vision and Image Understanding1995,61,1: | 1 |
| 14 | Comparison of broiler performance when fed diets containing grain from Roundup Ready ( NK603 ) , YieldGardxRoundup Ready( MON810xNK603 ) , non-transgenic control, or commercia corn显示文摘 | Taylor M L Hartnell G F Riordan S G | 2003 | Poultry Science2003,82,: | 1 |
| 15 | Nitrogen and phos- phorus remediation by three floating aquatic macrophytes in green- house-based laboratory-scale subsurface constructed wetlands 显示文摘 | Polomski R F Taylor M D Bielenberg D G | 2009 | Water Air Soil Pollution2009,197,14: | 1 |
| 16 | The equilibration of Deuterium in the Jovian atmosphere显示文摘 | Beer R Taylor F W | 1973 | Astrophys J1973,182,3: | 1 |
| 17 | Is Z- disk degradation responsible for postmortem tenderiza- tion显示文摘 | Taylor R G Geesink G H Thompson V F | 1995 | Journal of Animal Science1995,73,4: | 1 |
| 18 | Active shape models-their training and application显示文摘 | Cootes T F Taylor C J Cooper D H | 1995 | Computer Vision and Image Understanding1995,61,1: | 1 |
| 19 | A Model for the Mechanics of Jointed Rock显示文摘 | Goodman R F Taylor R L Brekke T L | | 0,,03: | 1 |
| 20 | Active Ap- pearance Models 显示文摘 | Cootes T F Edwards G J Taylor C J | 2001 | IEEE Trans on PAMI2001,23,6: | 1 |