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| 1 | Is endoscopic ultrasound examination necessary in the management of esophageal cancer?显示文摘Despite substantial efforts at early diagnosis, accurate staging and advanced treatments, esophageal cancer(EC) continues to be an ominous disease worldwide. Risk factors for esophageal carcinomas include obesity, gastroesophageal reflux disease, hard-alcohol use and tobacco smoking. Five-year survival rates have improved from 5% to 20% since the 1970 s, the result of advances in diagnostic staging and treatment. As the most sensitive test for locoregional staging of EC, endoscopic ultrasound(EUS) influences the development of an optimal oncologic treatment plan for a significant minority of patients with early cancers, which appropriately balances the risks and benefits of surgery, chemotherapy and radiation. EUS is costly, and may not be available at all centers. Thus, the yield of EUS needs to be thoughtfully considered for each patient. Localized intramucosal cancers occasionally require endoscopic resection(ER) for histologic staging or treatment; EUS evaluation may detect suspicious lymph nodes prior to exposing the patient to the risks of ER. Although positron emission tomography(PET) has been increasingly utilized in staging EC, it may be unnecessary for clinical staging of early, localized EC and carries the risk of false-positive metastasis(over staging). In EC patients with evidence of advanced disease, EUS or PET may be used to define the radiotherapy field. Multimodality staging with EUS, crosssectional imaging and histopathologic analysis of ER, remains the standard-of-care in the evaluation of early esophageal cancers. Herein, published data regarding use of EUS for intramucosal, local, regional and metastatic esophageal cancers are reviewed. An algorithm to illustrate the current use of EUS at The University of Texas MD Anderson Cancer Center is presented. | Tomas DaVee Jaffer A Ajani Jeffrey H Lee | 2017 | World Journal of Gastroenterology2017，23，5： | 11 |
| 2 | Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca2+ Control, and SR Ca2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy显示文摘 | Tomas O. St?len Morten Andre H?ydal Ole Johan Kemi Daniele Catalucci Marcello Ceci Ellen Aasum Terje Larsen Natale Rolim Gianluigi Condorelli Godfrey L. Smith Ulrik Wisl?ff | 2009 | Circulation Research2009，，6： | 2 |
| 3 | 大鼠垂体后叶多巴胺阳性纤维的起源显示文摘3%CT-HRP和3%WGA-HRP混合液注射入大鼠垂体后叶,用逆行追踪和免疫组织化学相结合的方法,研究垂体后叶多巴胺能神经纤维的起源。投射到大鼠垂体后叶-中间叶的多巴胺能细胞主要分布于第三脑室室周,即A14区,单个双标记神经元也在A15区腹侧部可以看到。A12区即弓状核内未见任何双标记TH阳性神经元。 | 鞠躬 刘少君 Tomas Hkfelt | 1990 | 解剖学报1990，21，3： | 2 |
| 4 | Nerve growth factor expression is up-regulated in the rat model of L-arginine-induced acute pancreatitis显示文摘 | Toma H Winston J Micci MA | 2000 | Gastroenterology2000，119，5： | 1 |
| 5 | Efficacy and tolerability of cancer pain management with controlled-release oxycodone tablets in opioid-naive cancer pain patients,stariing with Smg table显示文摘 | Koizumi W Toma H Watanabe K | 2004 | Jpn J Clin Oncol2004，34，10： | 1 |
| 6 | T cell infiltration into class Ⅱ MHC-disparate allografts and acute rejection is dependent on the IFN-gamma-induced chemokine Mig显示文摘 | Koga S Auerbach MB Engeman TM Novick AC Toma H Fairchild RL | 1999 | J Immunol1999，153，9： | 1 |
| 7 | Efficacy and tolerability of cancer pain management with controlled-release oxycodone tablets in opioid-naive cancer pain patients,starting with 5 mg tablets显示文摘 | Koizumi W Toma H Watanabe K | 2004 | Jpn J Clin 0ncol2004，34，： | 1 |
| 8 | Statin therapy prevents expansive remodeling in venous bypass grafts 显示文摘 | Qiang B Toma J Fujii H | 2012 | Atherosclerosis2012，223，1： | 1 |
| 9 | Statin therapy prevents expansive remodeling in venous bypass grafts显示文摘 | Qiang B Toma J Fujii H | | 0，，： | 1 |
| 10 | Immunohistoehemical distribution of c-Kit-positive cells and nitric oxide synthase-positive nerves in the guinea-pig small intestine显示文摘 | Toma H Nakamura K Emson PC | 1999 | J Auton Nerv Syst1999，75，23： | 1 |
| 11 | One versus two embryo transfer after IVF and ICSI: a randomized study显示文摘 | Martikainen H Tiitinen A Tomas C | 2001 | Hum Reprod2001，16，9： | 1 |
| 12 | Phase-only modulation using a twisted nematic liquid crystal televison显示文摘 | Barnes Tomas H Eiju Tomoaki Matusda Kiyofumi | 1989 | Applied Optics1989，28，22： | 1 |
| 13 | A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification显示文摘 | Saini SP Sonoda J Xu L Toma D Uppal H Mu Y | 2004 | Mol Pharmacol2004，65，2： | 1 |
| 14 | Persistence af human papillomavirus infection as a predictor for recurrence in carcinoma of the cervix after radiotherapy显示文摘 | Nagai Y Toma T Moromizato H | 2004 | Am J Obstet Gynecol2004，191，6： | 1 |
| 15 | Fine mapping of an immunodominant region of the transmembrane protein of the human immunodefieieney virus (HIV-1)显示文摘 | Sven-Holger D Tomas P Peter H | 1989 | J Virol Method1989，25，2： | 1 |
| 16 | Improved synthesis and characterization of pietet- spengler adducts of phenyl pyruvic acid and biogenie amines 显示文摘 | Tomas H | 1981 | Org Chem1981，46，： | 1 |
| 17 | Nerve growth factor regulates VR-1 mRNA levels in cultures of adult dorsal root ganglion neurons显示文摘 | Winston J Toma H Shenoy M | 2001 | Pain2001，89，23： | 1 |
| 18 | Rheological properties of rice starch at high moisture contents during twin screw extrusion 显示文摘 | Akdogan H Tomas R L Oliveira J C | 1997 | Lebensmittel - Wissenschaft Und - Technologies1997，30，： | 1 |
| 19 | The Oxidation Behavior of Sprayed MCrAlY Coatings显示文摘 | Brandl W Grabke H J Toma D | 1996 | SurCoat Technol1996，8687，： | 1 |
| 20 | Periprocedural hemodynamic instability with carotid angioplasty and stenting 显示文摘 | Taha MM Toma N Sakaida H | 2008 | Surg Neurol2008，70，3： | 1 |
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