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| 1 | Challenges in diagnosing adhesive small bowel obstruction显示文摘Adhesive small bowel obstruction(ASBO)is the most frequently encountered surgical disorder of the small intestine.Up to 80%of ASBO cases resolve spontaneously and do not require invasive treatment.It is important to identify such patients that will benefit from conservative treatment in order to prevent unnecessarily exposing them to the risks associated with surgical intervention,such as morbidity and further adhesion formation.For the remaining ASBO patients,timely surgical intervention is necessary to prevent small bowel strangulation,which may cause intestinal ischemia and bowel necrosis.While early identification of these patients is key to decreasing ASBO-related morbidity and mortality,the non-specific signs and laboratory findings upon clinic presentation limit timely diagnosis and implementation of appropriate clinical management.Combining the clinical presentation findings with those from other diagnostic imaging modalities,such as abdominal X-ray,computed tomography-scan and water-soluble contrast studies,will improve diagnosis of ASBO and help clinicians to better evaluate the potential of conservative management as a safe strategy for a particular patient.Nonetheless,patients who present with moderate findings by all these approaches continue to represent a challenge.A new diagnostic strategy is urgently needed to further improve our ability to identify early signs of strangulated bowel,and this diagnostic modality should be able to indicate when surgical management is required.A number of potential serum markers have been proposed for this purpose,including intestinal fatty acid binding protein andα-glutathione S transferase.On-going research is attempting to clearly define their diagnostic utility and to optimize their potential role in determining which patients should be managed surgically. | Thijs R van Oudheusden Bart AC Aerts Ignace HJT de Hingh Misha DP Luyer | 2013 | World Journal of Gastroenterology2013，19，43： | 7 |
| 2 | Microbleeds and the risk of recurrent stroke显示文摘 | Thijs V Lemmens R Schoofs C | 2010 | Stroke2010，41，： | 1 |
| 3 | Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients systolic hypertension显示文摘 | THIJS L FAGARD R | 1999 | JAMA1999，282，： | 1 |
| 4 | Lipoprotein (a) and Stroke:A Meta-Analysis of Observational Studies显示文摘 | Smolders B Lemmens R Thijs V | 2007 | Stroke2007，38，6： | 1 |
| 5 | Reducing prehospital delay in a- cute stroke显示文摘 | Bouckaert M Lemmens R Thijs V | 2009 | Nat Rev Neurol2009，5，9： | 1 |
| 6 | Lipoprotein (a) and stroke: A meta - analysis of observational studies 显示文摘 | Smolders B Lemmens R Thijs V | 2007 | Stroke2007，38，6： | 1 |
| 7 | Microbleeds and the risk of recurrent stroke显示文摘 | Thijs V Lemmens R Schoofs C | 2010 | Stroke2010，41，9： | 1 |
| 8 | Network meta-analysis: Simultaneous meta-analysis of common antiplatelet regimens after transient ischaemic attack or stroke 显示文摘 | Thijs V Lemmens R Fieuws S | 2008 | Eur Heart J2008，29，9： | 1 |
| 9 | Age at first introduction of cow milk products and other food products inrelation to infant atopie manifestations in the first 2 years of life:The koala birth cohort study 显示文摘 | Snijders BE Thijs C van Ree R etal | 2008 | Pediatrics2008，122，1： | 1 |
| 10 | Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension显示文摘 | Staessen JA Thijs L Fagard R | 1999 | JAMA1999，282，： | 1 |
| 11 | Randomized double-blind comparison of pllacebo and active treatment for older patients with isolated systolic hypertension显示文摘 | Staessen JA Fagard R Thijs L | 1997 | Lancet1997，350，： | 1 |
| 12 | Lipoprotein (a) and stroke : a meta-analysis of observational studies 显示文摘 | Smolders B Lemmens R Thijs V | 2007 | Stroke2007，38，6： | 1 |
| 13 | Randomised double-blind comparison of placebo and active treatment or older patients with isolated systolic hypertension显示文摘 | Staessen J A Fagard R Thijs L for the Systolic Hypertension in Europe (Syst-Eur) Trial investigators | 1997 | Lancet1997，350，： | 1 |
| 14 | Network meta-analysis: simuhaneous meta-analysis of common antiplatelet regimens after transient ischaemic attack or stroke 显示文摘 | THIJS V LEMMENS R FIEUWS S | 2008 | Eur Heart J2008，29，9： | 1 |
| 15 | Lipoprotein(a) and stroke: a meta-analysis of observational studies显示文摘 | Smolders B Lemmens R Thijs V | 2007 | Stroke2007，38，6： | 1 |
| 16 | Lipoprotein (a) and strok~:a meta- analysis of observational studies显示文摘 | Smolders B Lemmens R Thijs V | 2007 | Stroke2007，38，6： | 1 |
| 17 | Sudden unexpected death in epilepsy:People with nocturnal seizuresmay be at highest risk显示文摘 | Lamberts R Thijs RD Laffan A | 2012 | Epilepsia2012，53，2： | 1 |
| 18 | Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension显示文摘 | Staessen JA Fagard R Thijs L | 1997 | Lancet1997，350，： | 1 |
| 19 | Belgian Fabry study : prevalence of Fabry disease in a cohort of 1000 young patients with cerebrovascular disease 显示文摘 | Brouns R Thijs V Eyskens F | 2010 | Stroke2010，41，5： | 1 |
| 20 | Lipoprotein(a)and stroke:a Meta-analysis ofobservational studies显示文摘 | Smolders B Lemmens R Thijs V | 2007 | Stroke2007，38，： | 1 |
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