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292篇 您的检索式:作者名="TASHKIN DP"
    题名 作者 年代 出处 被引量
1为期四年的临床试验对噻托溴铵在慢性阻塞性肺疾病中的疗程评价显示文摘背景和目的:进一步观察噻托溴铵治疗COPD的长期效果。方法:通过随机、双盲试验,比较为期4年的噻托溴铵治疗COPD患者的疗效,4年期间允许患者使用除吸入抗胆碱能药物以外的任何呼吸科常用药物。要求患者年龄在40岁以上,使用支气管舒张剂后FEV1占预计值%≤70%,且FEV,/FVC占预计值%70%。主要终点是从第30天开始使用支气管舒张剂前后FEV1平均下降率。次要终点包括FVC测量值、圣乔治呼吸问卷(SGRQ)结果的变化、COPD急性加重以及病死率。结果:共入组5993例,Tashkin DP Celli B Senn S 金建敏 孙永昌 2009中华结核和呼吸杂志2009,32,3:2
2A 4-year trial of tiotropium in chronic obstructive pulmonary disease显示文摘Tashkin DP Celli B Senn S 2008N Engl J Med2008,359,15:1
3A 4-year trial oftiotropium in chronic obstructive pulmonary disease 显示文摘Tashkin DP Celli B Senn S 2008NEngl J Med2008,359,15:1
4Cyclophosphamide versus placebo in scleroderma lung disease显示文摘Tashkin DP Elashoff R Clements PJ 0,,25:1
5A 4-year trial of tiotropium in chronic obstructive pulmonary disease显示文摘Tashkin DP Celli B Senn S 2008N Engl J Med2008,359,15:1
6Bronchodilator respon- siveness in patients with COPD显示文摘Tashkin DP Celli B Decramer M 2008Eur Respir J2008,31,4:1
7Frequent exacerbations of chronic obstructive pulmo- nary disease--a distinct phenotype? 显示文摘Tashkin DP 2010N Engl J Med2010,363,12:1
8Formoterol and Tiotropium Compared With Tiotropium Alone for Treatment of COPD显示文摘Tashkin DP Pearle J Iezzoni D 2009COPD2009,6,1:1
9A 4-year trial of tiotropium in chronic obstructive pulmonary disease显示文摘Tashkin DP CeUi B Senn S 2008N Engl J Med2008,359,15:1
10The role of small air- ways in the lung disease显示文摘Shaw RJ Djukanovic R Tashkin DP 2002Respir Med2002,96,2:1
11A 4-year trial of tiotropium in chronic obstructive pulmonary disease 显示文摘Tashkin DP Celli B Senn S 2008N Engl J Med2008,359,15:1
12Eficacy and safety of budesonide and formoterul in one pressurized metered, dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trial显示文摘Tashkin DP Rennard SI Matin P 2008Drugs2008,68,6:1
13All - trans retinoic acid modulates the balance of matrix metalloproteinase - 9 and tissue inhibitor of metalloproteinase - 1 in patients with emphysema 显示文摘Mao JT Tashkin DP Belloni PN 2003CHEST2003,124,5:1
14Defining disease modification in chronic ob- structive pulmonary disease 显示文摘Halpin DM Tashkin DP 2009COPD2009,6,3:1
15Is a long-acting inhaled bronchodilator the first agent to use in stable chronic obstructive pulmonary disease ? 显示文摘Tashkin DP 2005Curr Opin Pulm Med2005,11,2:1
16Effects of arformoterol twice daily, tiotropium once daily, and their combination in patients with COPD显示文摘Tashkin DP Donohue JF Mahler DA 2009Respir Med2009,103,4:1
17Pharmacologic therapy : Novel approaches for chronic obstructive pulmonary disease显示文摘Bailey WC Tashkin DP 2007Proc Am Thorac Soc2007,4,7:1
18The role of small airway inflammation in asthma 显示文摘Tashkin DP 2002Allergy Asthma Proc2002,23,4:1
19Combination of formoterol and tiotropium in the treatment of COPD:effects on lung function显示文摘Cazzola M Tashkin DP 2009COPD2009,10,3:1
20Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease显示文摘Tashkin DP Elashoff R Clements PJ 2007Am J Respir Crit Care Med2007,176,10:1
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