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| 1 | Staged angioplasty versus regular carotid artery stenting in patients with carotid artery stenosis at high risk of hyperperfusion:a randomised clinical trial显示文摘Background and purpose Hyperperfusion(HP)is a devastating complication associated with carotid artery stenting(CAS)or endarterectomy.The efficacy and safety of staged angioplasty(SAP)in patients with CAS at high risk of HP remains unclear.We sought to determine whether SAP is superior to regular CAS in patients with high risk of HP.Methods A randomised,multicentre open-label clinical trial with blinded outcome assessment(STEP)was conducted.Patients with severe carotid stenosis at high risk of HP were randomly assigned(1:1)to the SAP or regular CAS group.The primary endpoint was hyperperfusion syndrome(HPS)and intracerebral haemorrhage(ICH)within 30 days after the procedure.Results From November 2014 to January 2017,a total of 64 patients were enrolled in 11 centres.33 patients were allocated to the SAP group and 31 to the regular CAS group.At 30 days,the rate of primary endpoint was 0.0%(0/33)in the SAP group and 9.7%(3/31)in the regular CAS group(absolute risk reduction(ARR),9.7%;95%CI−20.1% to 0.7%;p=0.11).As one of the secondary endpoints,the incidence of HP phenomenon(HPP)was lower in the SAP group than the regular CAS group(0.0%vs 22.6%,ARR,−22.6%;95% CI−36.8%to−10.2%;p=0.04).Conclusion The rate of HPS and ICH was not significantly lower in SAP group;the extended secondary endpoint of HPP,however,significantly reduced,which suggested that SAP may be a safe and effective carotid revascularisation procedure to prevent HP. | Dapeng Mo Baixue Jia Huaizhang Shi Yaxuan Sun Qingan Liu Chengzhe Fan Jianping Deng Jinglin Yuan Wei Wu Changchun Jiang Guilian Zhang Hanjun Du Ning Ma Feng Gao Xuan Sun Ligang Song Lian Liu Guangge Peng Yongjun Wang Yilong Wang Zhongrong Miao the STEP Study Group | 2021 | Stroke & Vascular Neurology2021，6，1： | 3 |
| 2 | 裸芯片的可靠性与老化工艺显示文摘从移动电话到 PDA 到数字音乐播放器,消费者对这些新的可移动电子设备的要求有两个共同点:(1)要求迅速增加的新特性和功能;(2)愿意为更小更轻而支付额外费用。这通常要用到多片裸芯片封装技术,如多芯片模块(MCM)和系统封装(SIP)等。 | Steve Steps 刘明 | 2003 | 中国集成电路2003，12，52： | 2 |
| 3 | The small footprint waste-water treatment process显示文摘 | STEP HENSON T MAN A UPTON J | 1993 | Chemistry & Industry1993，19，： | 1 |
| 4 | Object-oriented systems analysis modeling software in frame 显示文摘 | Sallu S Step J Mellor | 1996 | Journal of System and Software1996，32，2： | 1 |
| 5 | Algorithm of treatment of glucocorticoid induced osteoporosis-search for criteria显示文摘 | Stepán J | 2009 | Vnitr Lek2009，55，5： | 1 |
| 6 | equation actice:A review and recommended two- 显示文摘 | Anderson J C Gerbing D W modeling in pr step approach 103:411-423 | 1988 | Psychological Bulletin1988，，： | 1 |
| 7 | 显示文摘 | Haisong Qi Quanling Yang Lina Zhang eteThe dissolution of ceUu- lose in NaOH - based aqueous system by two - step process | 2011 | Cel- lulose2011，18，2： | 1 |
| 8 | Evaluation of health status of calves and impact on {eedlot performance: Assessment of retained ownership program for postweaning calves显示文摘 | Fulton R W Cook B J Step D L | 2002 | Can J Vet Res2002，66，3： | 1 |
| 9 | ESC guidelines for the management of acute myocardial infarction in patents presenting with STsegment elevation显示文摘 | Step PG James SK Atar D | 2012 | Eur Heart J2012，33，20： | 1 |
| 10 | Zinc treatment effects on corrosion behavior of alloy 600 in high temper- ature, hydrogenated water 显示文摘 | Step Hen E Ziemniak Michael Hanson | 2006 | Corrosion Science2006，48，： | 1 |
| 11 | Origin,characterization and fertility potential of abnormal sperm phenotypes in infertile men显示文摘 | Chemes EH Rawe YV Sperm pathology:a step beyond de- scriptive morphology | 2003 | Hum Reprod Update2003，9，5： | 1 |
| 12 | Wide-Stopband Microstrip Filters Using Dissimilar Quarter-Wavelength Impedance Resonators显示文摘 | LIN S C Bandpas Stepped 1011-10 DENG P H LIN Y S | 2006 | IEEE MTT2006，54，03： | 1 |
| 13 | Atomistic Monte Carlo simulations of three-dimensional polycrystal- line thin fihns显示文摘 | Step Motion on crystal sur- Physics 1966 37 (10) : Rubio J E Jaraiz M Martin-Bragado I | 2003 | Journal of Applied Physics2003，94，1： | 1 |
| 14 | ESC guidelines for the management of acute myocardial infarction in patents presenting with STsegment elevation显示文摘 | Step PG James SK Atar D | 2012 | Eur Heart J2012，33，20： | 1 |
| 15 | Ovulation induction increases pregnancy rate during intrauterine insemination compared with natural cycles显示文摘 | Streda R Stepán J Zadrobllková I | | 0，，06： | 1 |
| 16 | Effects of exposure to calves persistently infected with bovine viral diarrhea virus type I b and subsequent in- fection with Mannheima haemolytica on clinical signs and immune variables:model for bovine respiratory dis- ease via viral and bacterial interaction显示文摘 | Burciaga-Robles L O Step D L Krehbiel C R | 2010 | J Anita Sci2010，88，： | 1 |
| 17 | Structure-kinetics relationships of thermodestruction of some framework nitramines显示文摘 | Step anov R S Kruglyakova L A | 2010 | Russ J Gen Chem2010，80，： | 1 |
| 18 | Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study):a double-blind,randomised,placebo-controlled,test-of-concept trial显示文摘 | Buchbinder SP Mehrotra DV Duerr A Fitzgerald DW Mogg R Li D Gilbert PB Lama JR Marmor M Del Rio C McElrath MJ Casimiro DR Gottesdiener KM Chodakewitz JA Corey L Robertson MN Step Study Protocol Team | 2008 | Lancet2008，372，9653： | 1 |
| 19 | The influence of low job control on ambulatory blood pressure and perceived stress over the working day in men and women from the whitehall Ⅱ cohort 显示文摘 | Step toe A Willem sen G | 2004 | J Hypertens2004，22，： | 1 |
| 20 | A communication model of shared decision - making: Accounting for cancer treatment decisions 显示文摘 | Siminoff LA Step MM | 2005 | Health Psy- chol2005，，24： | 1 |
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