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| 1 | Silent diabetic nephropathy显示文摘AIM: To examine the risk of renal events in patients with biopsy-proven diabetic nephropathy(DN) and its possible associated factors.METHODS: Clinical and histological data of 60 patients diagnosed with diabetic nephropathy were retrospectively collected. Patients with evidence or suspicion of other nephropathies were excluded from the study. The final event was defined as renal replacement therapy(RRT) initiation or progression of chronic kidney disease(CKD), according to the KDIGO 2012 definition of a decrease in CKD category and a decrease in GFR of 25% or more. RESULTS: A total of 45 patients with a follow-up of at least 3 mo were included. Most of the patients presented type 2 DM, with a median age of 58.3 years old. The time of evolution of DM was 9.6 ± 7.8 years, although in 13 patients, it was less than 5 years. A total of 62% of patients reached the final event in a mean period of 3.4 years(95%CI: 2.1-4.7), with 21 of them requiring dialysis. The factors that were independently associated with renal survival were estimated glomerular filtration rate(e GFR) at the time of biopsy, cardiovascular disease(CVD) history and Hb A1 c less than 7%. Therefore, for each 10 m L/min per 1.73 m2 reduction in e GFR, we obtained a DN progression risk of HR = 2(1.3-3.0)(P = 0.001); patients with CVD were at greater risk for DN progression(HR = 2.8, 1.1-7.1, P = 0.032), and CKD patients with Hb A1 c < 7% demonstrated greater renal risk than patients with Hb A1 c ≥ 7%, with an HR of 2.9(1.0-8.4)(P = 0.054).CONCLUSION: A past history of CVD is a risk factor for DN progression. Levels of Hb A1 c less than 7% could favor an e GFR decrease in these patients. | Katia López-Revuelta Patricia Pea Galdo Ramona Stanescu Leticia Parejo Carmen Guerrero Elia Pérez-Fernández | 2014 | World Journal of Nephrology2014，3，1： | 2 |
| 2 | Dysembryoplastic neuroepithelial tumowurs: CT, MR finding and imaging fol- low-up: a study of 53 cases 显示文摘 | Stanescu CR Varlet P Beuron F | 2001 | J Neuroradiol2001，28，4： | 1 |
| 3 | Epidemiological survey of workers exposed to cobalt oxides,cobalt salts,and cobalt metal显示文摘 | Swennen B Buchet JP Stanescu D | 1993 | Br J Ind Med1993，50，9： | 1 |
| 4 | A spatial watermarking algorithm fordigital images显示文摘 | Burdescu D D Stanescu L | 2004 | Journal of Control Engineering and AppliedInformatics2004，6，3： | 1 |
| 5 | The Optimal Spacing Between Horizontal Cylinders in a Fixed Volume Cooled by Natural Convection 显示文摘 | Bejan A Fowler A J Stanescu G | 1995 | International Journal of Heat and Mass Transfer1995，38，11： | 1 |
| 6 | Airway obstruction, chronic expectoration and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils显示文摘 | Stanescu D Fournier M Lebargy F | 1996 | Thoax1996，51，3： | 1 |
| 7 | Bipolar plasma enucleation of the prostate vs open prostatectomy in large benign prostatic hyperplasia cases-a medium term, prospective,randomized comparison 显示文摘 | Geavlete B Stanescu F Iacoboaie C | 2013 | BJU Int2013，111，5： | 1 |
| 8 | Novel presentations of con- genital hyperinsulinism due to mutations in the MODY genes:HNF1A and HNF4A显示文摘 | Stanescu DE Hughes N Kaplan B | 2012 | 97(10) :E2026 - E20302012，97，10： | 1 |
| 9 | Risk HLA -DQAI and PLA(2) R1 alleles in idiopathic membranous ne phropathy显示文摘 | Stanescu HC Arcos - Burgos M Medlar A | 2011 | N Engl J Med2011，364，7： | 1 |
| 10 | Subungual exostosis of the big toe显示文摘 | Stanescu L Popescu CF Niculescu CE | 2009 | Rom J Morphol Embryol2009，50，3： | 1 |
| 11 | Hydrophilictoriccontactlensesinthecorrectionofastigmatism显示文摘 | FilipM StanescuS | 1998 | Ophthalmologia1998，42，1： | 1 |
| 12 | Airways obstruc- tion, chronic expecto - ration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neu- trophils显示文摘 | Stanescu D Sanna A Veriter C | 1996 | Thorax1996，1，3： | 1 |
| 13 | Airways obstruction, chronic ex-pectoration and rapid decline of FEV 1 in smokers are associated with in-creased levels of sputum neutrophils显示文摘 | Stanescu D Sanna A Venter C | 1996 | Thorax1996，51，1： | 1 |
| 14 | Dysembryoplastic neuroepithelial tumors: CT, MR findings and imaging follow up: A study of 53 cases显示文摘 | Stanescu Cosson R Varlet P Beuvon F | 2001 | J Neuroradiol2001，28，： | 1 |
| 15 | Perioperative mana- gement difficulties in parathyroidectomy for primary versus secon- dary and tertiary hyperparathyroidism 显示文摘 | Comeci M Stanescu B Trifanescu R | 2012 | Maediea (Buchar)2012，7，2： | 1 |
| 16 | Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration显示文摘 | Grimm C Wenzel A Stanescu D | 2004 | J Neurosci2004，24，： | 1 |
| 17 | Preparation and properties of novel slow-release NPK agroehemical formulations based on poly (acrylic acid ) hydrogels and liquid fertilizers 显示文摘 | Teodorescu M Lungu A Stanescu P O Neamt C | 2009 | Industrial Engineering Chemistry Research2009，48，14： | 1 |
| 18 | Risk HLA- DQA1 and PLA (2)R I alleles in idiopathic membranous ne- phropathy显示文摘 | Stanescu HC ArcoBurgos M Medlar A | 2011 | N Engl J Med2011，364，61： | 1 |
| 19 | Dysembryoplastic neuroepithelial tumors: CT, MR findings and imaging follow-up: a study of 53 cases显示文摘 | Stanescu Cosson R Varlet P Beuvon F | 2001 | J Neuroradiol2001，28，4： | 1 |
| 20 | Pulmonary hypertension secondary to chronic obstructive pulmonary disease显示文摘 | Gologanu D Stanescu C Bogdan MA | 2012 | Rom J Intern Med2012，50，4： | 1 |
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