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| 1 | Effect of corneal light scatter on vision: a review of the literature显示文摘The cornea is the transparent connective tissue window at the front of the eye.The physiological role of the cornea is to conduct external light into the eye,focus it,together with the lens,onto the retina,and to provide rigidity to the entire eyeball.Therefore,good vision requires maintenance of the transparency and proper refractive shape of the cornea.The surface structures irregularities can be associated with wavefront aberrations and scattering errors.Light scattering in the human cornea causes a reduction of visual quality.In fact,the cornea must be transparent and maintain a smooth and stable curvature since it contributes to the major part of the focusing power of the eye.In most cases,a simple examination of visual acuity cannot demonstrate the reduction of visual quality secondary light scattering.In fact,clinical techniques for examining the human cornea in vivo have greatly expanded over the last few decades.The measurement of corneal back scattering qualifies the degree of corneal transparency.The measurement of corneal forward-scattering quantifies the amount of visual impairment that is produced by the alteration of transparency.The aim of this study was to review scattering in the human cornea and methods of measuring it. | Leopoldo Spadea Giorgia Maraone Francesca Verboschi Enzo Maria Vingolo Daniele Tognetto | 2016 | International Journal of Ophthalmology(English edition)2016，9，3： | 7 |
| 2 | Photorefractive keratectomy after cataract surgery in uncommon cases: long-term results显示文摘AIM: To evaluate the efficacy and safety of the excimer laser correction of the residual refractive errors after cataract extraction with intraocular lens(IOL) implantation in uncommon cases.METHODS: Totally 24 patients with high residual refractive error after cataract surgery with IOL implantation were examined. Twenty-two patients had a history of phacoemulsification and IOL implantation, and two had extra-capsular cataract extraction with IOL implantation. Detailed examination of preoperative medical records was done to explain the origin of the post-cataract refractive errors. All patients underwent photorefractire keratectomy(PRK) enhancement. The mean outcome measures were refraction, uncorretted visual acuity(UCVA), best corrected visual acuity(BCVA) and corneal transparency and follow up ranged from 1 to 8 y.RESULTS: The principal causes of residual ametropia was inexact IOL calculation in abnormal eyes with high myopia and congenital lens abnormalities, followed by corneal astigmatism both suture induced and preexisting. After cataract surgery and before the laser enhancement the mean spherical equivalent(SE) was-0.56±3 D ranging from-4.62 to +2.25 D in high myopic patients, instead it was-1±1.73 D ranging from-3.25 to +3.75 D in the astigmatic eyes, with a mean cylinder of-3.75±0 ranging from-3 to +5.50 D. After laser refractive surgery the mean SE was 0.1±0.73, ranging from-0.50 to +1.50 in the myopic group, and it was-0.50±0.57 ranging from-1.25 to +0.50 in astigmatic patients, with a mean cylinder of-0.25±0.75. In myopic patients the mean UCVA and BCVA were 0.038±0.072 logMAR and 0.018±0.04 respectively, both ranging from 0.10 to 0.0. In astigmatic patients, the mean UCVA and BCVA were 0.213±0.132 and 0.00±0.0 respectively, UCVA ranging from 0.50 to 0.22 and BCVA was 0.00. All patients presented normal corneal transparency. No ocular hypertension was detected and no corneal haze was observed. All registered values remained stable also at the end line evaluation.CONCLUSION: The excimer laser treatment of residual refractive errors after cataract surgery with IOL implantation in abnormal eyes resulted in satisfactory and stable visual outcome with good safety and efficacy. | Anna Maria Roszkowska Mario Urso Giuseppe Alberto Signorino Leopoldo Spadea Pasquale Aragona | 2018 | International Journal of Ophthalmology(English edition)2018，11，4： | 4 |
| 3 | Long term results of no- alcohol laser epithelial keratomileusis and photorefractive keratectomy for myopia显示文摘AIM: To evaluate the long term clinical results of mechanical no-alcohol-assisted laser epithelial keratomileusis(LASEK) versus standard photorefractive keratectomy(PRK) for low-moderate myopia.METHODS: Twenty-five eyes treated with LASEK and twenty-five eyes treated with PRK were evaluated with a mean follow-up duration of 60 mo. Mechanical separation of the epithelium was performed with blunt spatula and without application of alcohol. Laser ablation was performed with the MEL-70 excimer laser. All patients were examined daily until epithelial closure; at 1, 3, 6,and 12 mo, and every year subsequently. Main outcome measures were uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA),manifest refraction, haze, efficacy and safety indexes.RESULTS: Twenty-one eyes and 22 eyes completed follow-up of 60 mo in LASEK and PRK group respectively. Manifest refraction at 60 mo follow-up was-0.01 and 0.26 in LASEK and PRK group respectively. In the LASEK group mean UDVA and mean CDVA after60 mo were 20/22 and 20/20 respectively(P >0.01). In the PRK group mean UDVA and mean CDVA at 60 mo follow-up were 20/20 and 20/20 after 60mo(P >0.01). The efficacy indexes were 0.87 and 0.95, and the safety indexes were1.25 and 1.4 respectively for LASEK group and PRK group.CONCLUSION: Both standard PRK and no-alcohol LASEK offer safe and effective correction of low-moderate myopia in the long term without any statistically significant difference between the two groups. | Leopoldo Spadea Francesca Verboschi Vittoria De Rosa Mariella Salomone Enzo Maria Vingolo | 2015 | International Journal of Ophthalmology(English edition)2015，8，3： | 3 |
| 4 | Excimer laserassisted lamellar keratoplasty for the surgical treatment of keratoconus 显示文摘 | Spadea L Giammaxia D Fiasca A Verrecchia V | 2009 | J Cataract Refract Surg2009，35，1： | 1 |
| 5 | Comparison of optical low coherence refractometry and ultrasound pachymetry in the measurement of central corneal thickness before and after photorefractive keratectomy显示文摘 | Spadea L Giammaria D Genova LD | 2007 | J Refract Surg2007，23，： | 1 |
| 6 | 显示文摘 | Spadea A Avvisati G | 1998 | Leukemia1998，12，6： | 1 |
| 7 | Mitoxantrone ,etoposide and intermediadose Ara-c(MEC):an effective regiment for poor risk acute myeloid leukemia显示文摘 | Petti M C Fazi P | 1993 | Leukemia1993，7，： | 1 |
| 8 | Strength and ductility of reinforced concrete beams externally reinforced with carbon fiber fabric显示文摘 | SPADEA G SWAMY R N | 2002 | Aci Structural Journal2002，99，2： | 1 |
| 9 | Role of the corneal epithelium in refractive changes following laser in situ keratomileusis for high myopia显示文摘 | Spadea L Fasciani R Necozione S | 2000 | J Refract Surg2000，16，2： | 1 |
| 10 | Corneal collagen cross-linking with riboflavin and UVA irradiation in pellucid marginal degeneration显示文摘 | Spadea L | 2010 | J Refract Surg2010，26，5： | 1 |
| 11 | Structure Behavior of Composite RC Beams with Externally Bonded CFRP 显示文摘 | Spadea G Bencardino F Swamy R N | 2000 | Journal of Composites for Construction2000，2，3： | 1 |
| 12 | Melphalan treatment in patients with myelofibrosis with myeloid metaplasia显示文摘 | Petti MC Latagliata R Spadea T | 2002 | Br J Haematol2002，116，： | 1 |
| 13 | Transepithelial corneal collagen cross- linking in ultrathin keratoconie corneas 显示文摘 | Spadea L Mencucci R | 2012 | Clln Ophthalmol2012，6，1： | 1 |
| 14 | Photorefractive keratectomy and laser in situ keratomileusis in refractive accommodative esotropia显示文摘 | Sabetti L Spadea L D'Alessandri L | 2005 | J Cataract Refract Surg2005，31，10： | 1 |
| 15 | Flap measurements with the Hansatome microkeratome显示文摘 | Spadea L Cerrone L Necozione S | 2002 | J Refract Surg2002，18，2： | 1 |
| 16 | Structural Behavior of Composite RC Beams with Externally Bonded CFRP显示文摘 | SPADEA G BENCARDINO F SWAMY R N | 1998 | Journal of Composites for Construction1998，2，3： | 1 |
| 17 | Structural behavior of composite RC beams with externally bonded CFRP 显示文摘 | Spadea G Bencardino F Swamy R N | 1998 | Journal of Composites for Construction1998，2，3： | 1 |
| 18 | Aspergillus flavus endophthalmitis after penetrating keratoplasty com- bined with cataract phacoemulsification and IOL implantation显示文摘 | SPADEA L ABBOUDA A ABICCA I | 2015 | Int Ophthalmol2015，35，： | 1 |
| 19 | Role of the corneal epithelium in refractive changes following laser in situ keratomileusis for high myopia显示文摘 | Fasciani R Necozione S | 2000 | J Refract Surg2000，16，2： | 1 |
| 20 | Shear Strength of RC Beams with Bonded Steel or FRP Plates 显示文摘 | Vincenzo Colotti Giuseppe Spadea | 2001 | ASCE Journal of Structural Englneering2001，127，4： | 1 |
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