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| 1 | Exercise training in hypertension:Role of microRNAs显示文摘Hypertension is a complex disease that constitutes an important public health problem and demands many studies in order to understand the molecular mechanisms involving his pathophysiology. Therefore, an increasing number of studies have been conducted and new therapies are continually being discovered. In this context, exercise training has emerged as an important non-pharmacological therapy to treat hypertensive patients, minimizing the side effects of pharmacological therapies and frequently contributing to allow pharmacotherapy to be suspended. Several mechanisms have been associated with the pathogenesis of hypertension, such as hyperactivity of the sympathetic nervous system and renin-angiotensin aldosterone system,impaired endothelial nitric oxide production, increased oxygen-reactive species, vascular thickening and stiffening, cardiac hypertrophy, impaired angiogenesis, and sometimes genetic predisposition. With the advent of microRNAs(miRNAs), new insights have been added to the perspectives for the treatment of this disease, and exercise training has been shown to be able to modulate the miRNAs associated with it. Elucidation of the relationship between exercise training and miRNAs in the pathogenesis of hypertension is fundamental in order to understand how exercise modulates the cardiovascular system at genetic level. This can be promising even for the development of new drugs. This article is a review of how exercise training acts on hypertension by means of specific miRNAs in the heart, vascular system, and skeletal muscle. | Vander Josédas Neves Tiago Fernandes Fernanda Roberta Roque Ursula Paula RenóSoci Stéphano Freitas Soares Melo Edilamar Menezes de Oliveira | 2014 | World Journal of Cardiology2014,6,8: | 9 |
| 2 | High Q-factor controllable phononic modes in hybrid phononic–dielectric structures显示文摘Phonon polariton resonances in the mid-infrared spectral range demonstrate properties superior to noble metal-based plasmonics,owing to smaller dissipative loss and better field confinement.However,a conventional way to excite the localized phonon resonance involves ion etching,which reduces the attainable quality factors(Q-factors)of the resonators.We show that by introducing a deep subwavelength layer of dielectric gratings on a phononic substrate,localized dipolar resonance and higher order modes with high Q-factors 96 and 195,respectively,can be excited.We further demonstrate,via experiments and simulations,that the resonant wavelength and field confinement can be controlled by coupling the localized hybrid mode with propagating surface phonon-polaritons.We also observed for the first time the coupling between a localized dipolar mode and a propagating higher-order surface phonon-polariton mode.The results will be useful in designing on-chip,low-loss,and highly integrated phononic devices in the infrared spectral domain. | Bo Qiang Alexander M.Dubrovkin Harish N.S.Krishnamoorthy Qian Wang Cesare Soci Ying Zhang Jinghua Teng Qi Jie Wang | 2019 | Advanced Photonics2019,1,2: | 4 |
| 3 | A critical plane approach to multiaxial fatigue damage including out-of-phase loading显示文摘 | Fatemi A Socie D F | 1988 | Fatigue and Fracture of Engineering Materials and Structures1988,11,: | 1 |
| 4 | A critical plane approach to muhiaxial fatigue damage including out-of phase loading显示文摘 | FATEMI A SOCIE D F | 1988 | Fatigue and Fracture of Engineering Materials and Structures1988,11,3: | 1 |
| 5 | Multiaxial fatigue damage models显示文摘 | Socie D F | 1987 | Journal of Engineering Materials and Technology Transactions of ASME1987,109,: | 1 |
| 6 | A randomized con- trolled study in patients with newly diagnosed severe aplastic anemia receiving antithymocyte globulin (ATG), cyelosporine, with or without G-CSF: a study of the SAA Working Party of the European Group for Blood and Marrow Transplantation 显示文摘 | Tichelli A Schrezenmeier H Socie G | 2011 | Blood2011,117,17: | 1 |
| 7 | Nanowire photodetectors显示文摘 | Soci C Zhang A Bao X Y | 2010 | J Nanosci Nanotechn2010,10,3: | 1 |
| 8 | Clinical practice guidlelines for the treatment of unresectable non -mall-cell lung Cancer显示文摘 | American Sociely of Clinical Oncology (Asco) | 1997 | Clin Oncol1997,15,9: | 1 |
| 9 | Chronic graft-versus- host disease: long-term results from a randomized trial on graft- versus-host disease prophylaxis with or without anti-T-cell globulin ATG-Fresenius 显示文摘 | Socie G Schmoor C Bethge WA | 2011 | Blood2011,117,23: | 1 |
| 10 | Multiaxial fatigue: Damage mechanisms and life predictions显示文摘 | Fatemi A Socie D F | 1989 | Nato Asi1989,159,: | 1 |
| 11 | A Critical Plane Approach to Multiaxial Fatigue Damage Including Out-of-phase Loading显示文摘 | FATEMI A SOCIE D F | 1988 | Fatigue and Fracture of Engineering Materials and Structures1988,11,3: | 1 |
| 12 | Multiaxial fatigue damage models显示文摘 | Socie D | 2009 | Journal of Engineering Materials and Teclmology2009,109,4: | 1 |
| 13 | Pregnancy outcomes after peripheral blood or bone marrow transplantation: A retrospective study显示文摘 | Salooja N Szydlo R Socie G | 2001 | Lancet2001,358,: | 1 |
| 14 | Simple rainflow counting algorithms显示文摘 | DOWNING S D SOCIE F D | 1982 | International Journal of Fatigue1982,4,1: | 1 |
| 15 | Nanowire photo- detectors 显示文摘 | SOCI C ZHANG A BAO X Y | 2010 | Journal of Nanoscience and Nanotechnolo- gy2010,10,3: | 1 |
| 16 | A critical plane approach to multiaxial fatigue damage including out-of-phase loading 显示文摘 | FATEMI A SOCIE D F | 1988 | Fatigue and Fracture of Engineering Materials and Structures1988,11,: | 1 |
| 17 | Silicon nanowire detec-tors showing phototransistive gain显示文摘 | ZHANG A YOU S F SOCI C | 2008 | Appl Phys Lett2008,93,12: | 1 |
| 18 | ZnO nanowire UV photo-detectors with high internal gain显示文摘 | Soci C Zhang A Xiang B | 2007 | Nano Lett2007,7,4: | 1 |
| 19 | ZnO nanowirc UV photodetectors with high Schottky internal gain 显示文摘 | SOCI C ZHANG A XIANG B | 2007 | Nano Lett2007,7,4: | 1 |
| 20 | Nanowire photodetec-tors显示文摘 | SOCI C ZHANG A BAO X Y | 2010 | Journal of Nanoscience and Nanotechnology2010,10,3: | 1 |