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94篇 您的检索式：作者名="Sirignano"

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	题名	作者	年代	出处	被引量
1	The potential of natural products for targeting PPARα显示文摘Peroxisome proliferator activated receptors(PPARs) α,-γ and-β/δ are ligand-activated transcription factors and members of the superfamily of nuclear hormone receptor. These receptors play key roles in maintaining glucose and lipid homeostasis by modulating gene expression. PPARs constitute a recognized druggable target and indeed several classes of drugs used in the treatment of metabolic disease symptoms, such as dyslipidemia(fibrates, e.g. fenofibrate and gemfibrozil) and diabetes(thiazolidinediones, e.g. rosiglitazone and pioglitazone) are ligands for the various PPAR isoforms. More precisely, antidiabetic thiazolidinediones act on PPARγ, while PPARα is the main molecular target of antidyslipidemic fibrates. Over the past few years, our understanding of the mechanism underlying the PPAR modulation of gene expression has greatly increased. This review presents a survey on terrestrial and marine natural products modulating the PPARα system with the objective of highlighting how the incredible chemodiversity of natural products can provide innovative leads for this 'hot' target.	Daniela Rigano Carmina Sirignano Orazio Taglialatela-Scafati	2017	Acta Pharmaceutica Sinica B2017，7，4：	9
2	Cavitation in anorifice flow显示文摘	Dabiri S Sirignano W A Joseph D D	2007	Physics of Fluids2007，19，7：	1
3	Performance increases for gas-tur bine engines through combustion inside the turbine显示文摘	Sirignano W A Liu F		J ou rnal of Propulsion and Power0，15，1：	1
4	On the equation for spherical-particle motion: Effect of Reynolds and acceleration numbers 显示文摘	Kim I Elghobashi S Sirignano W A	1998	Journal of Fluid Mechanics1998，367，：	1
5	Acute aortic dissection:natural history and classification显示文摘	Setacci F Sirignano P de-Donato G	2010	J Cardiovasc Surg(Torino)2010，51，5：	1
6	One dimensional analysis of liquid fueled combustion instability 显示文摘	Bhatia R Sirignano W A	1991	J Propulsion and Power1991，7，6：	1
7	Synthesis, characterization and cytotoxicity studies of methoxy al- kyl substituted metallocenes 显示文摘	Napoli M Saturnino C Sirignano E	2011	European Journal of Medicinal Chemistry2011，46，1：	1
8	Oscillatory Vaporization of Fuel Droplets in an Unstable Combustor显示文摘	Tong A Y Sirignano W A	1989	Journal of Propulsion and Power1989，5，3：	1
9	Fluid dynamics and transport of droplets and sprays 显示文摘	Sirignano W A	2000	J of Fluids Engineering2000，122，1：	1
10	Performance Increases for Gas-Turbine Engines Through Combustion Inside the Turbine显示文摘	Sirignano W A Liu F	1999	Journal of Propulsion and Power1999，15，1：	1
11	Droplet vaporization model for spray combustion calculations显示文摘	ABRAMZON B SIRIGNANO W A	1989	International Journal of Heat andMassTransfer1989，32，：	1
12	Performance increases for gas-turbineengines through combustion inside the turbine 显示文摘	Sirignano W A Liu F	1999	Journal ofPropulsion and Power1999，15，1：	1
13	Unsteady Droplet Combustion With Droplet Heating-Ⅱ: Conduction Limit 显示文摘	Law C K Sirignano W A	1977	Combustion and Flame1977，28，：	1
14	Droplet Vaporization Model for Spray Combustion Calculations 显示文摘	Abramzon B Sirignano W A	1989	International Journal of Heat and Mass Transfer1989，32，：	1
15	Performance increase for gas tur-bine engines through combustion inside the turbine显示文摘	Sirignano W A Liu F	1999	Journal of Propulsion and Power1999，15，1：	1
16	Performance increases for gas turbine engines through combustion inside the turbine 显示文摘	Sirignano W A Liu F	1999	Journal of Propulsion and Power1999，15，1：	1
17	The role of hybridprocedures in the treatment of critical limb ischemia 显示文摘	Setacci C Galzerano G Sirignano P	2013	JCardiovasc Surg (Torino)2013，54，6：	1
18	Ten years' experience in endovascular repair of popliteal artery aneurysm using the Viabahn endoprosthesis: a report from two Italian vascular centers显示文摘	Speziale F Sirignano P Menna D	2015	Ann Vase Surg2015，29，5：	1
19	Intera- ction between a cavitation bubble and shear flow显示文摘	DABIRI S SIRIGNANO W A JOSEPH D D	2010	Journal of Fluid Mechanics2010，651，：	1
20	Disintegration of planar liquid film impacted by two - dimensional gas jets显示文摘	Mehring C Sirignano W A	2003	Physics of Fluids2003，15，5：	1

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