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| 1 | Isolation of the mucilages from Hibiscus rosasinensis linn.and Okra(Abelmoschus esculentus linn.) and studies of the binding effects of the mucilages显示文摘Objective:To isolate and evaluate comparatively the binding efficacy of the mucilages obtained from the plants of Hibiscus rosasinensis and Okra(Abelmoschus esculentus).Methods:Extraction of mucilages from the leaves of Hibiscus and pods of Okra(Ladies finger) was carried out by a cold maceration process.The extracted mucilages were subjected to various physicochemical properties for its suitability as an excipient in the formulation of tablet dosage form.Different concentrations(10,8,5,2 and 1%w/v) of binder solutions of Hibiscus and Okra were used for the formulation of tablets and the formulated tablets were evaluated by studying the standard parameters like diameter,thickness,weight variation,hardness,friability,disintegration and in vitro dissolution.Stability studies of the formulated tablets were conducted for four weeks. Results:The formulated tablets prepared using the mucilages of both Hibiscus and Okra had good appearance.The in vitro drug release profile of the tablets prepared using Okra mucilage had an optimum of 90%at a mucilage concentration of 1%w/v concentration mucilage itself within 4 h.Conclusions:According to the observations,the lower concentration levels of Okra can be used as an alternative binder to starch.The higher concentration levels of Okra mucilage show a slow and sustained release,and can be considered as an alternative natural excipient in the modified drug delivery systems.At the same time,the above natural excipient of Hibiscus mucilage could be used as a platform for prolonged release if its binder concentrations are increased. | Ameena K Dilip C Saraswathi R Krishnan PN Sankar C Simi SP | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 8 |
| 2 | Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery显示文摘 | C K Simi T Emilia Abraham | 2007 | Bioprocess and Biosystems Engi- neering2007，30，： | 1 |
| 3 | Autostereoscopie three-dimensional viewer evaluation through comparison with conventional interfaces in laparoseopie surgery 显示文摘 | Silvestri M Simi M Cavallotti C | 2011 | Surg Innov2011，18，3： | 1 |
| 4 | The acute effects of 3,4-methylenedioxy- methamphetamine on oxidative stress in rat brain 显示文摘 | Simi c I Malicevic Z | 2008 | Med Pregl2008，61，56： | 1 |
| 5 | An eval- uation of algorithms for the remote sensing of eyanobacterial biomass 显示文摘 | Ruiz-Verdu A Simis S G H de Hoyos C | 2008 | Remote Sensing of Environment2008，112，： | 1 |
| 6 | Design, fabrication, and testing of a capsule with hybrid locomotion for gastrointestinal tract exploration 显示文摘 | Simi M Valdastri P Quaglia C | 2010 | IEEE/ASME Transactions on Mechatronics2010，15，2： | 1 |
| 7 | Chemoprevention of colon carcinogenesis by sulindac,a nonsteroidal anti-inflammatory agent显示文摘 | Rao C V Rivenson A Simi B | 1995 | Cancer Res1995，55，7： | 1 |
| 8 | Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery 显示文摘 | SIMI C K EM1LIA T | 2007 | Bioprocess Biosyst Eng2007，30，3： | 1 |
| 9 | Top management team diversity,group process and strategic consensus显示文摘 | Knight D Pearce C I Smith K Golan J D Sims H P Simi J H K A Flood P | 1999 | Strategic Management Jamal1999，20，3： | 1 |
| 10 | Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis,administered alone or in combination with celecoxib,a selective cyclooxygenase-2 inhibitor显示文摘 | Rao CV Indranie C Simi B | 2002 | Cancer Res2002，62，1： | 1 |
| 11 | 显示文摘 | Simi ci c M V Zduji c M Dimitrijevi c R | 2006 | J Power Sources2006，158，： | 1 |
| 12 | Thin film interdiffusion of Au and Sn at room temperature 显示文摘 | Marinkovi (′)/(c) | 1977 | Journal of Less-Common Metals1977，51，： | 1 |
| 13 | Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with Celecoxib, a selective Cyclooxygenase-2 inhibitor 显示文摘 | Rao CV Indranie C Simi B | | Cancer Res0，20，： | 1 |
| 14 | Towards a spectral theory of graphs based on the signless Laplacian显示文摘 | CVETKOVI'C D SIMI'C S | 2010 | Linear Algebra Appl2010，，432： | 1 |
| 15 | Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase - 2 inhibitor 显示文摘 | Rao CV Indranie C Simi B | 2002 | Cancer Res2002，62，1： | 1 |
| 16 | Chemoprevention of colon carcinogenesis by dietary curcumin,a naturally occurring plant phenolic compound显示文摘 | Rao C V Rivenson A Simi B | 1995 | Cancer Res1995，55，： | 1 |
| 17 | Hydrophobic grafted and cross-linked starch nan oparticles for drug delivery 显示文摘 | Simi C K Abraham Emilia T | 2007 | Bioprocess Biosyst Eng2007，30，3： | 1 |
| 18 | Kinetics and mechanism of reaction at room temperature in thin Au/metal couples 显示文摘 | Simi(′)/(c) V | 1988 | Thin Solid Films1988，156，： | 1 |
| 19 | Hydrogen absorption and electrochemical properties of Mg2 Ni-type alloys synthesized by mechanical alloying显示文摘 | Simi(c)i(c) M V Zduji(c) M Dimitrijevi(c) R | 2006 | J Power Sources2006，158，1： | 1 |
| 20 | Towards a spectral theory of graphs based on the signless Laplacian II 显示文摘 | CVETKOVI C D M SIMI C S K | 2010 | Linear Algebra Appl2010，432，9： | 1 |
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