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| 1 | Cytokines as biomarkers of inflammatory response after open versus endovascular repair of abdominal aortic aneurysms: a systematic review显示文摘一个腹的大动脉的动脉瘤(AAA ) 的修理是与有煽动性的串联的随后的激活的神经质、新陈代谢的压力相关的反应有关的一个高风险的外科的过程。与开的修理相对照(或) , endovascular 大动脉的动脉瘤修理(EVAR ) 由为更少提供广泛的切口,解剖,和织物操作似乎是手术后的压力到减少。然而,这些有益的效果可以是由代谢物在用在 endovascular 的导管的血栓的 intra 钠操作期间修理的 cytokines 和 arachidonic 酸的版本的偏移量,导致全身的煽动性的反应(先生) ,它是临床上叫的培植以后的症候群。在我们比较了的这系统的评论或与 EVAR,以 post-interventional,从改变导致传播 cytokine 的煽动性的反应铺平。我们寻求了在 EVAR 以后关于培植以后的症候群总结所有最近的证据。我们寻找了为临床的研究作为煽动性的反应的部分在 cytokines 的版本上报导在以后的 Medline (PubMed ) , ClinicalTrials.gov 和 Cochrane 图书馆开 / 常规并且 AAA 的 endovascular 修理。我们鉴别 17 学习检验 cytokine 层次在以后或对 EVAR。或似乎特别地比 EVAR 与一位更大的先生被联系,由增加的 cytokine 层次证实了 IL-6 和 IL-8 而 IL-1, IL-10 和 TNF- 出现了,冲突在二之间的结果或没有差别组织。聚酯 endografts 看起来断然在 EVAR 以后与培植以后的症候群的发生被相关。未来大未来的研究被保证位于在 surgical 以后的 cytokine 相互作用下面描出的机制煽动性的反应背景。 | Diamantis I TSILIMIGRAS Fragiska SIGALA Georgios KARAOLANIS Ioannis NTANASIS-STATHOPOULOS Eleftherios SPARTALIS Michael SPARTALIS Nikolaos PATELIS Alexandros PAPALAMPROS Chandler LONG Demetrios MORIS | 2018 | Acta Pharmacologica Sinica2018，39，7： | 5 |
| 2 | Diversity of endophytes across the soil-plant continuum for Atriplex spp. in arid environments显示文摘Endophytes are hypothesized to be transferred across the soil-plant continuum, suggesting both the transfers of endophytes from environment to plant and from plant to soil. To verify this hypothesis and to assess the role of locality, we evaluated the similarity of microbial communities commonly found both in soils and endophytic communities in three arid regions, i.e. the Jornada LTER(Long Term Ecological Research) site in New Mexico, USA, and the research station of Jordan University of Science and Technology(JUST) and Khanasri research station in Badia region of Jordan. Rhizosphere and non-rhizosphere soils, leaves and seeds of Atriplex spp. were sampled. Diversity and distribution of bacteria and fungi across the soil-plant continuums were assessed by tag-encoded FLX amplicon pyrosequencing and sequence alignment. Of the total bacterial OTUs(operational taxonomic units), 0.17% in Khanasri research station, 0.16% in research station of JUST, and 0.42% in Jornada LTER site were commonly found across all the plant and soil compartments. The same was true for fungi in two regions, i.e. 1.56% in research station of JUST and 0.86% in Jornada LTER site. However, in Khanasri research station, 12.08% of total fungi OTUs were found in at least one soil compartment and one plant compartment. Putative Arthrobacter, Sporosarcina, Cladosporium and members of Proteobacteria and Actinobacteria were found across all the soil-plant continuums. Ascomycota, mainly including Didymellaceae, Pleosporaceae and Davidiellaceae were present across all the soil-plant continuums. Microbial communities in two regions of Jordan were similar to each other, but both of them were different from the Jornada LTER site of USA. SIMPER(similarity percentage) analysis of bacterial and fungal taxa for both soil and endophyte communities revealed that dissimilarities of two bacterial genera(Arthrobacter and Sporosarcina) and two fungal genera(Cladosporium and Alternaria) are very high, so they play key roles in the soil-plant continuums. A weighed Pearson correlation analysis for the specific bacterial OTUs in the soil-plant continuums only showed high similarity between the two regions of Jordan. However, fungal groups showed higher similarities among all regions. This research supports the hypothesis of continuity of certain bacterial and fungal communities across the soil-plant continuums, and also explores the influences of plant species and geographic specificity on diversity and distribution of bacteria and fungi. | Mohammad E TAHTAMOUNI Sa'eb KHRESAT Mary LUCERO Jesus SIGALA Adrian UNC | 2016 | Journal of Arid Land2016，8，2： | 4 |
| 3 | Melatonin attenuates high fat diet-induced fatty liver disease in rats显示文摘AIM:To investigate melatonin's preventive action in oxidative stress in a rat model with high fat diet-induced non-alcoholic fatty liver disease(NAFLD).METHODS:NAFLD was induced by high fat diet(HFD)in adult,male,Wistar rats,weighing 180-230 g.After acclimatization for one week,they were randomly assigned to 6 experimental groups that comprised animals on regular diet plus 5 or 10 mg/kg melatonin,for 4 or 8 wk;animals on HFD,with or without 5 or 10 mg/kg melatonin,for 4 or 8 wk;and animals on HFD for 8 or 12 wk,with melatonin 10 mg/kg for the last 4 wk.Liver damage was assessed biochemically by the serum levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST),and histologically.Lipid peroxidation and oxidative stress were assessed by malondialdehyde and glutathione levels in liver tissue.Lipidemic indices and portal vein pressure were also measured.RESULTS:Compared to rats not receiving melatonin,rats on 5 or 10 mg/kg of melatonin had lower mean liver weight(-5.0 g and-4.9 g)(P < 0.001)and lower liver weight to body weight ratio(-1.0%)(P < 0.001),for the two doses,respectively.All rats fed HFD without melatonin developed severe,grade Ⅲ,steatosis.Rats on HFD with concurrent use of melatonin showed significantly less steatosis,with grade Ⅲ steatosis observed in 1 of 29(3.4%)rats on 10 mg/kg melatonin and in 3 of 27(11.1%)rats on 5 mg/kg melatonin.Melatonin was ineffective in reversing established steatosis.Melatonin also had no effect on any of the common lipidemic serum markers,the levels of which did not differ significantly among the rats on HFD,irrespective of the use or not of melatonin.Liver cell necrosis was significantly less in rats on HFD receiving melatonin than in those not on melatonin,with the AST levels declining by a mean of 170 U/L(P = 0.01)and 224 U/L(P = 0.001),and the ALT levels declining by a mean of 62.9 U/L(P = 0.01)and 93.4 U/L(P < 0.001),for the 5 and 10 mg/kg melatonin dose,respectively.Melatonin mitigated liver damage due to peroxidation and oxidative stress in liver tissue as indicated by a significant decline in MDA production by 12.7(P < 0.001)and 12.2(P < 0.001)μmol/L/mg protein/mg tissue,and a significant increase in glutathione by 20.1(P = 0.004)and 29.2(P < 0.001)μmol/L/mg protein/mg tissue,for the 5 and 10 mg/kg melatonin dose,respectively.CONCLUSION:Melatonin can attenuate oxidative stress,lessen liver damage,and improve liver histology in rats with high fat diet-induced NAFLD,when given concurrently with the diet. | Gregorios Hatzis Panayiotis Ziakas Nikolaos Kavantzas Aggeliki Triantafyllou Panagiotis Sigalas Ioanna Andreadou Konstantinos Ioannidis Stamatios Chatzis Konstantinos Filis Alexandros Papalampros Fragiska Sigala | 2013 | World Journal of Hepatology2013，5，4： | 4 |
| 4 | Band Structure of Elastic Waves in Two Dimensional Systems显示文摘 | Sigalas M Economou E N | 1993 | Solid State Communications1993，86，3： | 1 |
| 5 | Vascular endothelial cadherin expression in human carotid atherosclerotic plaque and its relationship with plaque morphology and clinical data 显示文摘 | Sigala F Vourliotakis G Georgopoulos S | 2003 | Eur J Vasc Endovasc Surg2003，26，5： | 1 |
| 6 | Elastic and acoustic wave band structure 显示文摘 | SIGALAS M ECONOMOU E N | 1992 | Journal of Sound and Vibra- tion1992，158，2： | 1 |
| 7 | Theoretical study of three dimensional elastic band gaps with the finite-difference time-domainmethod显示文摘 | Sigalas M M Garcia N | 2000 | Journal of Applied Physics2000，87，： | 1 |
| 8 | Different neurotransmitter systems are involved in the development of esophageal achalasia 显示文摘 | Missale G Missale C | 1995 | Life Sciences1995，56，16： | 1 |
| 9 | Band structure of elastic waves in two-dimensional systems 显示文摘 | SIGALAS M ECONOMOU E N | 1993 | Solid State Commun1993，86，3： | 1 |
| 10 | Evidence for thepresence of alpha 1 adrenoceptor subtypes in the human ureter显示文摘 | Sigala S Dellabella M Milanese G | 2005 | Neurourol Urodyn2005，24，2： | 1 |
| 11 | Effect of SPS consoli- dation parameters on submicron Cu and Cu-CNT composites for thermal management显示文摘 | Sule R Olubambi P A Sigalas I | 2014 | Powder Technol2014，258，： | 1 |
| 12 | Evidence for the presence of alphal adrenoceptor subtypes in the human ureter 显示文摘 | Sigala S Dellabella M Milanese G | 2005 | Neuronurol Urodyn2005，24，2： | 1 |
| 13 | Evidence for the presence of alpha1 adrenoceptor subtypes in the human ureter显示文摘 | Sigala S Dellabella M Milanese G | 2005 | Neurourol Urodyn2005，24，2： | 1 |
| 14 | Different neurotransmitter systems are involved in the development of esophageal achalasia显示文摘 | Sigala S Missale G Missale C | 1995 | Life Sciences1995，56，16： | 1 |
| 15 | Elastic and a- coustic wave band structure显示文摘 | SIGALAS M M ECONOMOU E N | 1992 | Journal of Sound and Vibration1992，158，2： | 1 |
| 16 | Frequency modulation in the transmitivity of wave guides in elastic-wave band-gap materials显示文摘 | Kafesaki M Sigalas M M García N | 2000 | Physical Review Letters2000，85，19： | 1 |
| 17 | Elastic and Acoustic Wave Band Structure显示文摘 | Sigalas M M Economou E N | 1992 | Journal of Sound and Vibration1992，158，2： | 1 |
| 18 | Angiopoietin-2 levels are elevated in exudative pleural effusions显示文摘 | Kalomenidis I Kollintza A Sigala I | 2006 | Chest2006，129，5： | 1 |
| 19 | Evidence for the presense of aipha 1-adrenocepter subtypes in the human ureter显示文摘 | Sigala S Dellabella M Milanese G | 2005 | Neuroural Uradyn2005，24，2： | 1 |
| 20 | The optical absorption of nanowire arrays显示文摘 | LAGOS N SIGALAS M M NIARCHOS D | 2011 | Photonics and Nanostructures- Fundamentals and Applications2011，9，： | 1 |
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