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| 1 | Impact of primary tumour location on colorectal liver metastases: A systematic review显示文摘BACKGROUND Colorectal cancer(CRC)is the third most common cause of cancer-related death worldwide.Despite significant advances in screening,surgical management and adjuvant therapies,average 5-year survival seldom exceeds 60%in most developed nations.Metastatic disease represents the primary cause of mortality in patients with CRC,and the liver is the most common location for distant tumour spread.Up to 25%of patients are found to have synchronous liver metastases at the time of diagnosis and a further 30%-40%will develop metachronous disease in the course of follow-up.It has been suggested that primary tumour location[right side versus left side,primary tumour location(PTL)]can influence oncological outcomes in this patient group and that this should be considered in prognostic models and therapeutic decision-making algorithms.This suggestion is not universally accepted and there have been conflicting reports in the literature to date.AIM To provide a comprehensive summary of the available evidence regarding the impact of PTL on oncological outcomes in patients with colorectal cancer liver metastases(CRCLM).METHODS MEDLINE,EMBASE and COCHRANE were searched for relevant publications using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology.Data on oncological outcomes was then extracted from full text articles that met the predefined inclusion criteria.RESULTS A total of 41 studies were identified that met predefined inclusion criteria for this review.In 21 out of 38 studies that provided data on overall survival,a statistically significant improvement in overall survival was reported in patients with left sided primary tumours.These studies included a total of 13897 patients compared with 4306 patients in the studies that did not show a significant difference.Eight studies noted a similar trend towards improved disease-free or progression-free survival.Several authors observed distinct patterns of relapse after treatment of hepatic metastases according to PTL;for example hepatic recurrence after treatment of CRCLM appears to occur more aggressively with right-sided CRC.CONCLUSION Taken together,the findings of the present review indicate that PTL may have a role as an independent prognostic factor when determining treatment and disease surveillance strategies in CRC.The mechanisms responsible for this variation remain poorly understood,but are likely to relate to molecular,histological and embryological differences,as well as inherent differences in therapeutic sensitivity. | George Bingham Alysha Shetye Reena Suresh Reza Mirnezami | 2020 | World Journal of Clinical Oncology2020，11，5： | 3 |
| 2 | Global myocardial strain assessment by different imaging modalities to predict outcomes after ST-elevation myocardial infarction:A systematic review显示文摘AIM: To conduct a systematic review relating myocardial strain assessed by different imaging modalities for prognostication following ST-elevation myocardial infarction(STEMI).METHODS: An online literature search was performed in Pub Med and OVID® electronic databases to identify any studies that assessed global myocardial strain parameters using speckle-tracking echocardiography(STE) and/or cardiac magnetic resonance imaging(CMR) techniques [either myocardial tagging or feature tracking(FT) software] in an acute STEMI cohort(days 0-14 post-event) to predict prognosis [either development of major adverse cardiac events(MACE)] or adverse left ventricular(LV) remodelling at follow-up(≥ 6 mo for MACE,≥ 3 mo for remodelling). Search was restricted to studies within the last 20 years. All studies that matched the pre-defined search criteria were reviewed and their results interpreted. Due to considerable heterogeneity between studies,metaanalysis was not performed.RESULTS: A total of seven studies(n = 7) were identified that matched the search criteria. All studies used STE to evaluate strain parameters- five(n = 5) assessed global longitudinal strain(GLS)(n = 5),one assessed GLS rate(GLS-R)(n = 1) and one assessed both(n = 1). Three studies showed that GLS independently predicted the development of adverse LV remodelling by multivariate analysis- odds ratio between 1.19(CI: 1.04-1.37,P < 0.05) and 10(CI: 6.7-14,P < 0.001) depending on the study. Four studies showed that GLS predicted the development of MACE- hazard ratio(HR) between 1.1(CI: 1-1.1,P = 0.006) and 2.34(1.10-4.97,P < 0.05). One paper found that GLS-R could significantly predict MACEHR 18(10-35,P < 0.001)- whilst another showed it did not. GLS <-10.85% had sensitivity/specificity of 89.7%/91% respectively for predicting the development of remodelling whilst GLS <-13% could predict the development of MACE with sensitivity/specificity of 100%/89% respectively. No suitable studies were identified that assessed global strain by CMR tagging or FT techniques.CONCLUSION: GLS measured acutely post-STEMI by STE is a predictor of poor prognosis. Further research is needed to show that this is true for CMR-based techniques. | Abhishek Shetye Sheraz A Nazir Iain B Squire Gerald P McCann | 2015 | World Journal of Cardiology2015，7，12： | 2 |
| 3 | Variability of Nonionellina labradorica Dawson in Surface Sediments from Kongsfjorden,West Spitsbergen显示文摘Kongsfjorden 是在邻近北极和大西洋的谎言浇的 Spitsbergen (Svalbard 群岛) 的峡湾集中并且因此是一个合适的地点理解气候的效果在生态系统上变化。译解转变大西洋水的侧面的移流的效果(打) 在峡湾,有孔虫目的测试的空间变化,他们的测试尺寸变化和马厩以内,在表面沉积的同位素的作文(13C 和 18O ) 被学习。全部的器官的碳并且组织上,分析也被执行。主导的 benthic 有孔虫类包括了 Nonionellina labradorica, Elphidium excavatum, Cassidulina reniforme, Quinqueloculina stalkeri 和 Islandiella islandica。Nonionellina labradorica 是在外部峡湾的占优势的种类,而 Elphidium excavatum 和 Cassidulina reniforme 在内部峡湾是主导的。全部的器官的碳和在峡湾以内的 Nonionellina labradorica 的测试尺寸高度被相关(r= 0.97 )并且两个都向象温度侧面一样基于分发和许多 Nonionellina labradorica 的内部峡湾显示出一个减少的趋势,我们建议在侧面的移流有很少或没有主要变化在立即的过去在峡湾以内打。 | Suhas SHETYE Rahul MOHAN Sunil Kumar SHUKLA Sudhakar MARUTHADU Rasik RAVINDRA | 2011 | Acta Geologica Sinica(English Edition)2011，85，3： | 2 |
| 4 | Analysis of genes, transcripts, and proteins via DNA ligation显示文摘 | Conze T Shetye A Tanaka Y | 2009 | Annu Rev Anal Chern (Palo Alto Calif)2009，2，： | 1 |
| 5 | The coastal current of western India during the northeast monsoon 显示文摘 | SHETYE S R GOUVEIA A D SHENOI S S C | 1991 | Deep-Sea Res Part A1991，38，： | 1 |
| 6 | Intracerebral inflammatory response to experimental brain contusion显示文摘 | Holmen S Mathiesen T Shetye J | 1995 | Acta Neurochir Wien1995，132，13： | 1 |
| 7 | Physicochemical and biological studies of Schiff bases derived from 3-phenyl salicylaldehyde 显示文摘 | Shetye S S Manyadeo M S Laxmeshwar N B | 1999 | Research Journal of Chemistry and Environment1999，3，1： | 1 |
| 8 | Intracerebral inflammatory response to experimental brain contusion显示文摘 | Holmni S Mathiesen T Shetye J | 1995 | Acta Neurlchir1995，132，1： | 1 |
| 9 | Hydrography and circulation in the western Bay of Bengal during the northeast monsoon显示文摘 | Shetye S R Gouveia A D Shankar D | 1996 | Journal of Geophysical Research1996，101，14： | 1 |
| 10 | Nutrient characteristics of the water masses and their seasonal variability in the eastern equatorial Indian Ocean显示文摘 | SARDESSAI S SHETYE S MAYA M V | 2010 | Marine Environmental Research2010，70，3： | 1 |
| 11 | Presurgical nasoalveolar molding treatment in cleft lip and palate patients显示文摘 | Grayson B Shetye P Cutting C | 2005 | Cleft Journal2005，1，4： | 1 |
| 12 | Benign paroxysmal positional vertigo in a child: an infrequent complication following a fairground ride and post- cochlear implant surgery显示文摘 | Shetye A | 2012 | Cochlear Implants Int2012，13，： | 1 |
| 13 | Intracerebral inflam- matory response to experimental brain contusion显示文摘 | Holmen S Mathiesen T Shetye J | 1995 | Acta Neur- oehir (Wien)1995，132，13： | 1 |
| 14 | Facial growth of adults with unoperated clefts显示文摘 | Shetye PR | 2004 | Clin Plast Surg2004，31，2： | 1 |
| 15 | Presurgical nasoalveolar mold- ing treatment in cleft lip and palate patients显示文摘 | Grayson B H Shetye P R | 2009 | Indiarr J Plast Surg2009，42，： | 1 |
| 16 | Incidence oforonasal fistula formation after nasoalveolar moldingand primary cleft repair显示文摘 | Dec W Shetye PR Grayson BH | 2013 | J Craniofac Surg2013，24，1： | 1 |
| 17 | Incidence of Oronasal Fistula Formation After Nasoalveolar Mold- ing and Primary Cleft Repair显示文摘 | Dec Wojciech M D Shetye Pradip R Grayson Barry H | 2013 | Journal of Craniofacial surgery2013，24，1： | 1 |
| 18 | Benign paroxysmal positional vertigo in a child : aninfrequent complication following a fairground ride and post-cochlear implant surgery 显示文摘 | Shetye A | 2012 | Cochlear Implants Int2012，13，3： | 1 |
| 19 | Ultraviolet irradiationinitiates ectopic foot formation in regenerating hydra and promotesbudding 显示文摘 | Ghaskadbi SS Shetye L Chiplonkar S | 2005 | J Biosci2005，30，： | 1 |
| 20 | Benign paroxysmal positional vertigo in a child: an infrequent complication following a fairground ride and post-cochlear implant surgery显示文摘 | Shetye A | 2012 | Cochlear Implants Int2012，13，3： | 1 |
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