|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Structuring Nonlinear Wavefront Emitted from Monolayer Transition-Metal Dichalcogenides显示文摘The growing demand for tailored nonlinearity calls for a structure with unusual phase discontinuity that allows the realization of nonlinear optical chirality,holographic imaging,and nonlinear wavefront control.Transition-metal dichalcogenide(TMDC)monolayers offer giant optical nonlinearity within a few-angstrom thickness,but limitations in optical absorption and domain size impose restriction on wavefront control of nonlinear emissions using classical light sources.In contrast,noble metal-based plasmonic nanosieves support giant field enhancements and precise nonlinear phase control,with hundred-nanometer pixellevel resolution;however,they suffer from intrinsically weak nonlinear susceptibility.Here,we report a multifunctional nonlinear interface by integrating TMDC monolayers with plasmonic nanosieves,yielding drastically different nonlinear functionalities that cannot be accessed by either constituent.Such a hybrid nonlinear interface allows second-harmonic(SH)orbital angular momentum(OAM)generation,beam steering,versatile polarization control,and holograms,with an effective SH nonlinearityχ^((2))of~25 nm/V.This designer platform synergizes the TMDC monolayer and plasmonic nanosieves to empower tunable geometric phases and large field enhancement,paving the way toward multifunctional and ultracompact nonlinear optical devices. | Xuanmiao Hong Guangwei Hu Wenchao Zhao Kai Wang Shang Sun Rui Zhu Jing Wu Weiwei Liu Kian Ping Loh Andrew Thye Shen Wee Bing Wang Andrea Alù Cheng-Wei Qiu Peixiang Lu | 2020 | Research2020，，1： | 5 |
| 2 | Immunogenicity and safety of NVSI-06-07 as a heterologous booster after priming with BBIBP-CorV:a phase 2 trial显示文摘The increased coronavirus disease 2019(COVID-19)breakthrough cases pose the need of booster vaccination.We conducted a randomised,double-blinded,controlled,phase 2 trial to assess the immunogenicity and safety of the heterologous prime-boost vaccination with an inactivated COVID-19 vaccine(BBIBP-CorV)followed by a recombinant protein-based vaccine(NVSI-06-07),using homologous boost with BBIBP-CorV as control.Three groups of healthy adults(600 individuals per group)who had completed two-dose BBIBP-CorV vaccinations 1–3 months,4–6 months and≥6 months earlier,respectively,were randomly assigned in a 1:1 ratio to receive either NVSI-06-07 or BBIBP-CorV boost.Immunogenicity assays showed that in NVSI-06-07 groups,neutralizing antibody geometric mean titers(GMTs)against the prototype SARS-CoV-2 increased by 21.01–63.85 folds on day 28 after vaccination,whereas only 4.20–16.78 folds of increases were observed in control groups.For Omicron variant,the neutralizing antibody GMT elicited by homologous boost was 37.91 on day 14,however,a significantly higher neutralizing GMT of 292.53 was induced by heterologous booster.Similar results were obtained for other SARS-CoV-2 variants of concerns(VOCs),including Alpha,Beta and Delta.Both heterologous and homologous boosters have a good safety profile.Local and systemic adverse reactions were absent,mild or moderate in most participants,and the overall safety was quite similar between two booster schemes.Our findings indicated that NVSI-06-07 is safe and immunogenic as a heterologous booster in BBIBP-CorV recipients and was immunogenically superior to the homologous booster against not only SARS-CoV-2 prototype strain but also VOCs,including Omicron. | Nawal Al Kaabi Yun Kai Yang Jing Zhang Ke Xu Yu Liang Yun Kang Ji Guo Su Tian Yang Salah Hussein Mohamed Saif ElDein Shuai Shao Sen Sen Yang Wenwen Lei Xue Jun Gao Zhiwei Jiang Hui Wang Meng Li Hanadi Mekki Mekki Walid Zaher Sally Mahmoud Xue Zhang Chang Qu Dan Ying Liu Jing Zhang Mengjie Yang Islam Eltantawy Peng Xiao Zhao Nian Wang Jin Liang Yin Xiao Yan Mao Jin Zhang Ning Liu Fu Jie Shen Liang Qu Yun Tao Zhang Xiao Ming Yang Guizhen Wu Qi Ming Li | 2022 | Signal Transduction and Targeted Therapy2022，7，7： | 2 |
| 3 | in vitro study of DNA interaction with trichlorobenzenes by spectroscopic and voltammetric techniques显示文摘 | SHEN Haoyu SHAO Xiaoli XU Hua ct al | 2011 | Int J Electrochem Sci2011，6，3： | 1 |
| 4 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis 显示文摘 | Huang N E Shen Z Long S al | 1998 | Proceedings of the Royal Society of London1998，454，： | 1 |
| 5 | Determination of pore size distribution and adsorption of methane and CCl4 on activated carbon by molecular simulation显示文摘 | CAO D WANG W SHEN Z et al | 2002 | Carbon NY2002，40，13： | 1 |
| 6 | Pelvic fixation for adult scoliosis显示文摘 | Shen FH Mason JR Shimer AL | 2013 | Eur Spine J2013，22，2： | 1 |
| 7 | Detect overlapping and hierarchical communily structure in networks 显示文摘 | Shen H Cheng X Cai K el al | 2009 | Physiea A2009，388，8： | 1 |
| 8 | 显示文摘 | Luboshitzky R Lavie L Shen - Orr Z el al | 2005 | Obes Res2005，13，4： | 1 |
| 9 | Nanobactcria:a polliblc ctiology for type III prostatitis 显示文摘 | Shen X Min g A Li X ct al | 2010 | Urol2010，184，1： | 1 |
| 10 | Characterization of axon formation in the embryonic stem cell - derived mo- toneuron 显示文摘 | Pan HC Wu YT Shen SC el al | 2011 | Cell Transplanl2011，20，4： | 1 |
| 11 | True phosphorus digestibility and the endogenous phosphorus outputs associated with corn for growing pigs are determined with the regression analysis technique显示文摘 | Shen Y R Fan M Z Ajakaie A el al | 2002 | J Nutr2002，132，： | 1 |
| 12 | Quantitative real-time RT- PCR detection for survivin, CK20 and CEA in peripheral blood of colorectal cancer patients显示文摘 | Shen C Hu LH Xia L el al | 2008 | Jpn J Clin Oncol2008，38，11： | 1 |
| 13 | Over-expression of the special AT rich sequetace binding protein 1 (SATBI) promotes the progression of nasopharyngeal carcinoma: association with E- BV LMP-1 expression显示文摘 | SHEN ZH ZENG YM GUO JL el al | 2013 | Transl Med2013，11，1： | 1 |
| 14 | Differential galanin re- ceptor-1 and galanin expression by 5-HT neurons in dor- sal raphd nucleus of rat and mouse: evidence for spe- cies-dependent modulation of serotonin transmission显示文摘 | Lama JA Shen P J Gundlach AL | 2003 | Eur J Neurosci2003，17，3： | 1 |
| 15 | Inversion of secondary chiral alcohols in toluene with the tunable complex of R3N-R' COOH 显示文摘 | Shi X X Shen C L Yao J Z ct al | 2010 | Tetrahedron: Asymmetry2010，21，： | 1 |
| 16 | Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic:suppression of CYLD gene by LEFl显示文摘 | Liu P Xu B Shen W et al | 2011 | Leukemia2011，，： | 1 |
| 17 | Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells显示文摘 | Townsend DM Shen H Staros AL | 2002 | Mol Cancer Ther2002，1，12： | 1 |
| 18 | An intrinsic therapy of gold nanoparticles infocal cerebral ischemia-repcrfusion injury in rats显示文摘 | Liu Z Shen Y Wu Y e al | 2013 | J Biomed Nanotech-nol2013，9，6： | 1 |
| 19 | Clinical utility of wireless capsule endoscopy experience with 200 cases 显示文摘 | Tatar EL Shen EH Palance AL | 2006 | J Clin Castroen- terol2006，40，2： | 1 |
| 20 | The enhanced oral absorption and decreased food effect of new nanoemulsion of megestrol acetate 显示文摘 | SHEN QB LEE DH BAE YH YANG SG at al | 2011 | KSBB Fall Meeting2011，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员