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| 1 | Photodynamic therapy vs radiofrequency ablation for Barrett's dysplasia: Efficacy,safety and cost-comparison显示文摘AIM:To compare effectiveness,safety,and cost of photodynamic therapy(PDT)and radiofrequency ablation(RFA)in treatment of Barrett’s dysplasia(BD).METHODS:Consecutive case series of patients undergoing either PDT or RFA treatment at single center by a single investigator were compared.Thirty-three patients with high-grade dysplasia(HGD)had treatment with porfimer sodium photosensitzer and 630 nm laser(130 J/cm),with maximum of 3 treatment sessions.Fifty-three patients with BD(47 with low-grade dysplasia-LGD,6 with HGD)had step-wise circumferential and focal ablation using the HALO system with maximum of 4 treatment sessions.Both groups received proton pump inhibitors twice daily.Endoscopic biopsies were acquired at 2 and 12 mo after enrollment,with 4-quadrant biopsies every 1 cm of the original BE extent.A complete histological resolution response of BD(CR-D)was defined as all biopsies at the last endoscopy session negative for BD.Fisher’s exact test was used to assess differences between the two study groups for primary outcomes.For all outcomes,a two-sided P value of less than 0.05 was considered to indicate statistical significance.RESULTS:Thirty(91%)PDT patients and 39(74%)RFA were men(P=0.05).The mean age was 70.7±12.2 and 65.4±12.7(P=0.10)year and mean length of BE was 5.4±3.2 cm and 5.7±3.2 cm(P=0.53)for PDT and RFA patients,respectively.The CR-D was(18/33)54.5%with PDT vs(47/53)88.7%with RFA(P=0.001).One patient with PDT had an esophageal perforation and was managed with non-surgical measures and no perforation was seen with RFA.PDT was five times more costly than RFA at our institution.The two groups were not randomized and had different BD grading are the limitations of the study.CONCLUSION:In our experience,RFA had higher rate of CR-D without any serious adverse events and was less costly than PDT for endoscopic treatment of BD. | Atilla Ertan Irum Zaheer Arlene M Correa Nirav Thosani Shanda H Blackmon | 2013 | World Journal of Gastroenterology2013，19，41： | 7 |
| 2 | Extubation force depends upon angle of force application and fixation technique: a study of 7 methods显示文摘 | Wagner JL Shandas R Lanning CJ | 2014 | BMC Anesthesiol2014，14，： | 1 |
| 3 | Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors显示文摘 | Li M Stenmark K R Shandas R | 2009 | J V asc Res2009，46，6： | 1 |
| 4 | Unconstrainedrecovery characterization of shape-memory polymer net-works for cardiovascular applications 显示文摘 | Yakacki C M Shandas R Lanning C | 2007 | Biomaterials2007，28，14： | 1 |
| 5 | Development of a noninvasive ultrasound color M-mode means of estimating pulmonary vascular resistance in pediatric pulmonary hypertension:mathematical analysis,in vitro validation and preliminary clinical studies显示文摘 | SHANDAS R WEINBERG C IVY D D | 2001 | Circulation2001，104，8： | 1 |
| 6 | Integrating urban form and demographics in water-demand management: an em- pirical case study of portland, Oregon显示文摘 | Shandas V Hossein Parandvash G | 2010 | Environment and Planning B: Planning and Design2010，37，1： | 1 |
| 7 | Development of a noninvasive ul-trasound color M-mode means of estimating pulmonary vascular resist-ante in pediatric pulmonary hypertension:mathematical analysis,in vitro validation,and preliminary clinical studies显示文摘 | Weinberg C Ivy DD | 2001 | Circulation2001，104，8： | 1 |
| 8 | Integrating urban form and demographics in water-de- mand management: an empirical case study of Portland, Oregon显示文摘 | SHANDAS V HOSSEIN P G | | Environment and Planning B: Planning and Design0，37，1： | 1 |
| 9 | , Unconstrained recovery characterization of shape-memory polymer networks for cardiovascular applications 显示文摘 | Christopher Michael Yakacki Robin Shandas Craig Lanning | 2007 | Biomaterials2007，28，14： | 1 |
| 10 | Pyruvate improves redox status and decreases indicators of hepatic apoptosis during hemorrhagic shock in swine 显示文摘 | Paul D M John C Shanda W | 2002 | Am J Physiol2002，283，4： | 1 |
| 11 | Development and validation of echo PIV 显示文摘 | Kim H Hertzberg J Shandas R | 2004 | Exp Fluids2004，36，3： | 1 |
| 12 | R2R3 MYB transcription factor PtrMYB192 regulates flowering time in Arabidopsis by activating FLOWERING LOCUS C显示文摘 | Liu Shanda Wang Xiaoping Li Eryang | 2013 | Plant Bi- ol2013，56，4： | 1 |
| 13 | Capacitive micromachined ultrasonic transducers using commercial multi-user MUMPs process: Capability and limitations显示文摘 | L1U J OAKLEY C SHANDAS R | 2009 | Ultrasonics2009，49，： | 1 |
| 14 | Rates of urbanisation and the resiliency of air and water quality 显示文摘 | DUH J D SHANDAS V CHANG H | 2008 | Science of the Total Environment2008，400，： | 1 |
| 15 | Unconstrained recovery characterization of shape-memory polymer networks for cardiovascular applica tions显示文摘 | Christopher Michael Yakacki Robin Shandas Craig Lanning | 2007 | Biomaterials2007，28，14： | 1 |
| 16 | Development of A noninvasive ultrasound color M-Mode means of estimating pulmonary vascular resistance in pediatric pulmonary hypertension 显示文摘 | Shandas R Weinberg C Dunbar DI | 2001 | Circulation2001，104，8： | 1 |
| 17 | A Novel Fixation Procedure to Eliminate Covered Self-Expanding Metal Stent Migration显示文摘 | Calvin D. Lyons Min P. Kim Shanda H. Blackmon | 2012 | The Annals of Thoracic Surgery2012，，5： | 1 |
| 18 | Rates ??of urbanization and the resiliency of air and water quality显示文摘 | Duh Jiunn-Der Shandas Vivek Chang Heejun | 2008 | Science of the Total Environment2008，400，13： | 1 |
| 19 | Development and validation ofecho PIV显示文摘 | Kim HB Hertzberg JR Shandas R | 2004 | Exp Fluids2004，36，3： | 1 |
| 20 | Use of intravascular ultrasound to measure local compliance of the pediatric pulmonary artery:in vitro studies 显示文摘 | Weinberg CE Hertzberg JR Shandas R | 2002 | J Am Soc Eehocardiogr2002，15，12： | 1 |
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