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	题名	作者	年代	出处	被引量
1	Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery显示文摘AIM: To investigate the effects of an enteral supple-ment containing antioxidants on circulating levels of antioxidants and indicators of oxidative stress after major gastrointestinal surgery.METHODS: Twenty-one patients undergoing major upper gastrointestinal tract surgery were randomised in a single centre, open label study on the effect of postoperative enteral nutrition supplementedwith antioxidants. The effect on circulating levels of antioxidants and indicators of oxidative stress, such as F2-isoprostane, was studied. RESULTS: The antioxidant enteral supplement showed no adverse effects and was well tolerated. After surgery a decrease in the circulating levels of antioxidant parameters was observed. Only selenium and glutamine levels were restored to pre-operative values one week after surgery. F2-isoprostane increased in the first three postoperative days only in the antioxidant supplemented group. Lipopolysaccharide binding protein (LBP) levels decreased faster in the antioxidant group after surgery.CONCLUSION: Despite lower antioxidant levels there was no increase in the circulating markers of oxidative stress on the first day after major abdominal surgery. The rise in F2-isoprostane in patients receiving the antioxidant supplement may be related to the conversion of antioxidants to oxidants which raises questions on antioxidant supplementation. Module AOX restored the postoperative decrease in selenium levels. The rapid decrease in LBP levels in the antioxidant group suggests a possible protective effect on gut wall integrity. Further studies are needed on the role of oxidative stress on outcome and the use of antioxidants in patients undergoing major abdominal surgery.	Mireille FM van Stijn Gerdien C Ligthart-Melis Petra G Boelens Peter G Scheffer Tom Teerlink Jos WR Twisk Alexander PJ Houdijk Paul AM van Leeuwen	2008	World Journal of Gastroenterology2008，14，45：	4
2	Early seizures : causal events or predisposition to adult epilepsy? 显示文摘	Dulac O Nabbout R Plouin P Chiron C Scheffer I	2007	Lancet Neurol2007，6，7：	1
3	Peptide transport by the multidrug resistance protein MRP1 显示文摘	de Jong M C Slootstra J W Scheffer G L	2001	Cancer Res2001，61，6：	1
4	Abnormal corneal ep- ithelial wound healing inpartial-thichness removal of lim- bal epithelium 显示文摘	JAMES J Y C SCHEFFER C G T	1991	Invest Ophthalmol Vis Sci1991，32，1：	1
5	Temperature-programmed reduction of CoO/MoO3 catalysts 显示文摘	Arnoldy P Franken M C Scheffer B	1985	J Catal1985，96，：	1
6	SCN1A Mutations and Epilepsy 显示文摘	MULLEY J C SCHEFFER I E PETROU S	2005	Human Mutation2005，25，6：	1
7	The Mr 193,000 vault protein is up-regulated in multidrug-resistant cancer cell lines 显示文摘	SCHROEIJERS A B SIVA A C SCHEFFER G L	2000	Cancer Res2000，60，4：	1
8	Temperature-programmed reduction of CoO-MoO3/ Al2O3 catalysts显示文摘	ARNOLDY P FRANKEN M C SCHEFFER B	1985	J Catal1985，96，2：	1
9	Mutant GABA(A) receptor gamma- 2 - subunit in childhood absence epilepsy and febrile seizures显示文摘	Scheffer LM Marini C Petrou S	2001	Nature Genet2001，28，：	1
10	Right ventricular outflow and apical pacing comparably worsen the echocardiographic normal left ventricle显示文摘	TEN C T SCHEFFER M G SUTHERLAND G R	2008	Eur J Echocardiogr2008，9，：	1
11	Membrane transport proteins associated with drug resistance expressed in human melanoma显示文摘	Schadendorf D Makki A Stahr C van Dyck A Wanner R Scheffer GL	1995	Am J Pathol1995，147，：	1
12	Enzymie analysis of the crabtree effect in glucose-limited chemostat cultures of Saccharomyces cerevisiae显示文摘	POSTMA E VERDUYN C SCHEFFERS W A	1989	Appl Environ Microbiol1989，55，2：	1
13	Regional conlrc31 of atrial fibrillation by rapid Pacing in conscious dogs显示文摘	Allessie M Kirchhof C Scheffer GJ	1991	J Circulation1991，84，4：	1
14	The Solubility of naphthalene in supercritical ethylene 显示文摘	Diepen G A M Scheffer F E C	1948	JACS1948，70，12：	1
15	Active Hidden Markov Models for Information Extraction 显示文摘	Scheffer T Decomain C Wrobel S	2001	The Locture Notes in Computer Science2001，，：	1
16	Timing-and crosstalk-driven area routing显示文摘	Tseng H P Scheffer L Sechen C	2001	IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems2001，20，4：	1
17	Natural resistance of wood to microbial deterioration显示文摘	Scheffer T C	1966	Annual Review of Phytopathology1966，，：	1
18	SCN1A testing for epilepsy: application in clinical practice 显示文摘	Hirose S Scheffer IE Marini C	2013	Epilapsia2013，5，：	1
19	Navigating the thannels and heyond: tmraw-lling Ihe genelies of Ihe epihpsies显示文摘	Helbig I Scheffer l E Mullcy J C	2008	Luncet Neurol2008，7，3：	1
20	Induced nitric oxide impairs relaxation but not contraction in endotoxinexposed rat pulmonary arteries 显示文摘	Boer C Groeneveld A B Scheffer G J	2005	J Surg Res2005，127，2：	1

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